Eric L Simpson, Anna De Benedetto, Mark Boguniewicz, Peck Y Ong, Stephanie Lussier, Miguel Villarreal, Lynda C Schneider, Amy S Paller, Emma Guttman-Yassky, Jon M Hanifin, Jonathan M Spergel, Kathleen C Barnes, Gloria David, Briahnna Austin, Donald Y M Leung, Lisa A Beck
BACKGROUND: Atopic dermatitis (AD) is a chronic inflammatory skin condition with a highly variable clinical phenotype. OBJECTIVE: This study aimed to identify historical and clinical features and biomarkers associated with AD severity. METHODS: A US registry of extensively phenotyped AD participants (0.73-80 yrs) were enrolled at nine academic centers. Information on family and personal medical history, examination, skin swabs (culture), and serum biomarkers were collected to evaluate their association with AD severity...
May 12, 2023: Journal of Allergy and Clinical Immunology in Practice