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Keywords febrile neutropenia in emergen...

febrile neutropenia in emergency room

https://read.qxmd.com/read/37799822/a-multimodal-strategy-to-improve-health-care-for-pediatric-patients-with-cancer-and-fever-in-peru
#1
JOURNAL ARTICLE
Ana Mendieta, Ligia Rios Lopez, Maria Vargas Arteaga, Essy Maradiegue, Walter Delgadillo Arone, Carlos Rueda Bazalar, Alexis Holguin, Carlos Santillan Salas, Ivan Maza, Maysam Homsi, Frankly Farias Barrios, Claudia Assayag, Liliana Vásquez, Claudia Pascual, Miguela Caniza
OBJECTIVE: The DoTT (Decreasing Time to Therapy) project aimed to minimize the interval between fever onset and medical interventions for children with febrile neutropenia. The objective of this study was to determine the effect of implementing the DoTT project on the hospital time to antibiotic (TTA) and patient time to arrival (PTA) at the hospital in children with febrile neutropenia admitted to the emergency department. METHODS: The DoTT project was implemented at a Peruvian hospital and followed the World Health Organization (WHO) multimodal improvement strategy model...
2023: Pan American Journal of Public Health
https://read.qxmd.com/read/34882499/protecting-high-risk-oncology-patients-during-the-covid-19-pandemic-by-creating-an-isolated-outpatient-clinic
#2
JOURNAL ARTICLE
Seyed Mohammad Abedi, Manidhar Lekkala, Bahar Moftakhar, Tammy Clarke, Arpan Patel
PURPOSE: Delivering care for immunocompromised, high-risk patients with cancer during a pandemic has proven challenging. Patients with cancer on chemotherapy have a high risk of mortality if contracted COVID-19. If a patient goes directly to the emergency room, multiple contact points with other individuals can lead to unnecessary exposures from any airborne virus, such as COVID-19. Our cancer center has implemented an isolated clinic with personal protective equipment and direct access to a COVID-19 rule-out floor to manage those with febrile neutropenia (FN)...
December 9, 2021: JCO oncology practice
https://read.qxmd.com/read/34245642/association-of-an-emergency-department-febrile-neutropenia-intervention-protocol-with-time-to-initial-antibiotic-treatment
#3
JOURNAL ARTICLE
Justin A Seltzer, Olga Frankfurt, Demetrios N Kyriacou
BACKGROUND: Earlier initial antibiotic treatment for febrile neutropenia is associated with improved clinical outcomes. This study was conducted to evaluate the association of an emergency department (ED) intervention protocol with time to initial antibiotic treatment for febrile neutropenia patients. METHODS: We conducted a cohort study of adult ED febrile neutropenia patients before and after implementation of an intervention protocol. Analyses included comparison of means and medians, Kaplan-Meier estimates, multivariable regression analyses, interrupted time-series analyses, and causal mediation analyses...
January 2022: Academic Emergency Medicine
https://read.qxmd.com/read/33785710/emergency-oncology-admissions-during-covid-19-pandemic-a-major-institution-experience-from-saudi-arabia
#4
JOURNAL ARTICLE
O Elemam, E Tashkandi, S Abdelkhalek, I Shalaby, R Baraka
BACKGROUND: The WHO has declared the coronavirus disease 2019 (COVID-19) pandemic in March 2020. Cancer patients are considered a highly susceptible group. The effect of this pandemic on cancer mortality is still unknown. AIM: Our aim is to know whether or not we need to postpone cancer treatment during viral pandemics in the future. MATERIALS AND METHODS: A retrospective observational study from March 1, 2020 to June 1, 2020, included cancer patients on active treatment, who have been admitted to our oncology center through the emergency unit, and patients who received oncology treatment in the outpatient treatment unit...
March 2021: Experimental Oncology
https://read.qxmd.com/read/32853124/observational-study-of-clinical-toxicity-with-different-formulations-of-docetaxel-in-breast-cancer-patients
#5
MULTICENTER STUDY
Eva González-Haba-Peña, Margarita Garrido-Siles, María Jose Martínez-Bautista, Amparo Burgos-San José, Azucena Aldaz-Pastor, Irene Mangues-Bafalluy
OBJECTIVE: To analyze the excipients and impurities contained in the various docetaxel products available on the market and find out  whether they may be responsible for any of the different adverse events  associated with the use of docetaxel in patients with breast cancer  receiving adjuvant or neoadjuvant treatment. METHOD: This is a prospective, multicenter, longitudinal observational, study carried in 26 hospitals in Madrid, Catalonia, Andalusia, and the Valencia Region...
August 24, 2020: Farmacia Hospitalaria
https://read.qxmd.com/read/32818937/febrile-neutropenia-in-patients-with-solid-tumors-undergoing-intravenous-chemotherapy
#6
JOURNAL ARTICLE
João Moreira-Pinto, Inês Leão, Carolina Palmela, Francisco Branco, João Godinho, Pedro Simões, Luisa Leal-Costa, Fabio Lopes, Ana Faria, Mafalda Casa-Nova, Ana Escária, Filipa Costa, Isabel Galvão, José Teixeira, José Luís Passos-Coelho
INTRODUCTION: Febrile neutropenia (FN) is a potentially life-threatening complication of systemic chemotherapy (CT) that often requires hospital admission. Delay in diagnosis and treatment are associated with higher morbidity and mortality. OBJECTIVE: We aimed to determine the factors that influence FN episodes outcomes in the emergency room (ER). METHODS: This was a retrospective study of all FN episodes (with a collected blood culture [BC]) that occurred between 2012 and 2016 at our institution...
2020: Oncology Research and Treatment
https://read.qxmd.com/read/32453199/cefepime-versus-cefepime-plus-amikacin-as-an-initial-antibiotic-choice-for-pediatric-cancer-patients-with-febrile-neutropenia-in-an-era-of-increasing-cefepime-resistance
#7
JOURNAL ARTICLE
Na Hee Lee, Ji-Man Kang, Ji Won Lee, Hee Jae Huh, Nam Yong Lee, Keon Hee Yoo, Ki Woong Sung, Hong Hoe Koo, Yae-Jean Kim
BACKGROUND: We investigated the treatment outcomes before and after the addition of amikacin to cefepime monotherapy as an initial empirical antibiotic treatment in pediatric cancer patients with febrile neutropenia. METHODS: This was a retrospective historical cohort study. The subjects were pediatric cancer patients who visited the emergency room at the Samsung Medical Center, Seoul, Korea, due to chemotherapy-induced febrile neutropenia, between January 2011 and December 2016...
October 2020: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/29652973/-febrile-neutropenia-in-cancer-patients-management-in-the-emergency-room
#8
REVIEW
Daniel Rivera-Salgado, Kathia Valverde-Muñoz, María L Ávila-Agüero
Febrile neutropenia is a life-threatening condition that requires immediate attention, especially in patients with chemotherapy-related neutropenia. Patients with febrile neutropenia have a much greater risk of developing bacterial disease, and fever may be the only indicator of severe bacterial infection. Adequate management of febrile neutropenia emphasizes early recognition of patients, risk stratification, and antibiotic therapy administration during the first 60 minutes of admission to an emergency room...
2018: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://read.qxmd.com/read/28152881/setting-quality-improvement-priorities-for-women-receiving-systemic-therapy-st-for-early-stage-breast-cancer-ebc-using-population-level-administrative-data
#9
JOURNAL ARTICLE
Lingsong Yun, Alejandro Gonzalez, Melanie Powis, Nathan Taback, Christopher M Booth, Maureen E Trudeau, Monika K Krzyzanowska
299 Background: Routine evaluation of evidence informed quality measures (QM) can drive improvement in cancer systems by highlighting potential gaps in care. Targeting quality improvement at QMs that demonstrate substantial variation has the potential to make the largest impact on quality at a population level. We aimed to use variation in performance to set priorities for improving the quality of ST for women with EBC. METHODS: EBC cases diagnosed 2006 - 2010 in Ontario, Canada were identified in the Ontario Cancer Registry and linked deterministically to multiple health care databases...
March 2016: Journal of Clinical Oncology
https://read.qxmd.com/read/26324292/-fast-identification-of-febrile-neutropenia-improves-the-outcome
#10
REVIEW
Sofia Johansson, Lars Henrik Jensen
The purpose of this article is to describe the management of febrile neutropenia in the medical emergency room. Symptoms and signs of inflammation in patients receiving chemotherapy may be blunted or absent and fever may be the only sign of severe infection. Early initiation of empirical antibiotics is essential for the outcome. A beta-lactam antibiotic is the treatment of choice and the regimen should be re-evaluated frequently in absence of clinical improvement. The treating oncologist should always be involved for advice and for assuring adjustments in future chemotherapy...
August 31, 2015: Ugeskrift for Laeger
https://read.qxmd.com/read/25585617/emergency-room-visits-and-hospital-admission-rates-after-curative-chemotherapy-for-breast-cancer
#11
JOURNAL ARTICLE
Natalia M Pittman, Wilma M Hopman, Mihaela Mates
PURPOSE: Curative chemotherapy for breast cancer is associated with significant toxicities including emergency room (ER) visits and hospital admissions (HAs), events that are underreported in clinical trials. This study examined the reasons for, and factors associated with, ER visits and HA after curative chemotherapy for breast cancer in a tertiary Ontario hospital. PATIENTS AND METHODS: A retrospective study of all patients who completed at least one cycle of curative chemotherapy for breast cancer in 2011 and 2012 was conducted...
March 2015: Journal of Oncology Practice
https://read.qxmd.com/read/25089219/delayed-presentation-of-dpd-deficiency-in-colorectal-cancer
#12
REVIEW
Lindsey Law, Jane Rogers, Cathy Eng
Case Study  Mr. D., a 55-year-old male, presented to the medical oncology service with a diagnosis of stage III adenocarcinoma of the sigmoid colon. He presented 7 weeks post sigmoid colectomy with lymph node resection and was initiated on adjuvant chemotherapy with CAPOX (capecitabine [Xeloda] and oxaliplatin [Eloxatin]). Standard dosing was used: oxaliplatin at 130 mg/m(2) on day 1 and capecitabine at approximately 2,000 mg/m(2)/day (rounded to the nearest 500-mg tablet size) for 14 days on and 7 days off (1 cycle = 21 days)...
May 2014: Journal of the Advanced Practitioner in Oncology
https://read.qxmd.com/read/23180404/febrile-neutropenia-outline-of-management
#13
JOURNAL ARTICLE
Sapna Oberoi, Renu Suthar, Deepak Bansal, R K Marwaha
Febrile neutropenia is a common emergency encountered in children receiving chemotherapy for a malignancy. Left untreated, it can lead to serious morbidity and mortality. Febrile neutropenia is suspected in any patient on chemotherapy who presents with fever. Prompt evaluation and management by the primary contact pediatrician is essential for a successful outcome. A detailed history and physical examination is warranted to identify source of infection, although two thirds of them may not have localizing symptoms or signs...
February 2013: Indian Journal of Pediatrics
https://read.qxmd.com/read/22184489/assessment-and-management-of-febrile-neutropenia-in-emergency-departments-within-a-regional-health-authority-a-benchmark-analysis
#14
JOURNAL ARTICLE
D Szwajcer, P Czaykowski, D Turner
OBJECTIVES: Febrile neutropenia is considered an oncologic emergency, for which prompt initiation of antibiotics is essential. METHODS: We conducted a retrospective cohort study for the 2006 calendar year involving all adult oncology patients presenting with febrile neutropenia to a regional health authority's emergency departments. The objective was to determine the time from triage to antibiotic administration and its impact on patient outcomes. RESULTS: We identified 68 patients presenting with febrile neutropenia, most of whom (76%) were seen in tertiary care centers...
December 2011: Current Oncology
https://read.qxmd.com/read/21945189/a-european-survey-relating-to-cancer-therapy-and-neutropenic-infections-nurse-and-patient-viewpoints
#15
JOURNAL ARTICLE
Kay Leonard
PURPOSE: Severe neutropenia and febrile neutropenia (FN) are the major causes of morbidity, treatment interruptions and dose reductions in patients undergoing chemotherapy. The European Oncology Nursing Society (EONS) conducted an European survey to evaluate nurse perspectives on prevention of infection and FN in this setting, and how much they educate their patients about this. A separate survey explored these issues in patients receiving chemotherapy. METHODS: 217 nurse participants were identified by EONS from the membership database and 473 cancer patients who were receiving/had received chemotherapy were identified through patient advocacy groups...
September 2012: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://read.qxmd.com/read/21418423/clinical-practice-guidelines-for-children-with-cancer-presenting-with-fever-to-the-emergency-room
#16
COMPARATIVE STUDY
Samart Pakakasama, Kulvadee Surayuthpreecha, Uthen Pandee, Usanarat Anurathapan, Vimolratne Maleewan, Umaporn Udomsubpayakul, Punnee Butthep, Pitak Santanirand, Nongnuch Sirachainan, Suradej Hongeng
BACKGROUND: Patients with febrile neutropenia (FN) may develop severe infection, septic shock, and death. To improve the outcome of pediatric oncology patients with suspected FN, clinical practice guidelines were developed for these patients at the emergency room (ER). The objective of the present study was to evaluate compliance of the clinical practice guidelines for children with cancer presenting with fever to the ER and adverse outcomes after using the guidelines. METHODS: A retrospective cohort study was undertaken of children with cancer presenting with fever to the ER from January 2007 to December 2008 after the clinical guidelines were implemented...
December 2011: Pediatrics International: Official Journal of the Japan Pediatric Society
https://read.qxmd.com/read/16045870/-hospitalizations-for-varicella-in-the-hospital-infantil-la-fe-valencia-spain-2001-2004
#17
JOURNAL ARTICLE
A I Piqueras Arenas, M C Otero Reigada, D Pérez-Tamarit, F Asensi Botet, N Diosdado Ortín, M Santos Durantez
INTRODUCTION: Varicella is a common, highly contagious disease. It is usually benign but has potentially serious complications. PATIENTS AND METHODS: To assess the clinical characteristics and the associated cost of varicella hospitalization, we reviewed the medical records of children hospitalized for varicella between 2001 and 2004. Children with coincidental varicella hospitalized for a different reason were excluded. RESULTS: Of 1177 children with varicella attended at the emergency room, 101 (8...
August 2005: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://read.qxmd.com/read/15762370/overdose-of-lomustine-report-of-two-cases
#18
JOURNAL ARTICLE
Abdullah Büyükçelik, Hakan Akbulut, Bülent Yalçin, Feyyaz Ozdemir, Fikri Içli
Two male patients with high-grade gliomas were treated with subtotal or total resection and radiotherapy followed by a lomustine-containing chemotherapy regimen. Both patients took lomustine at an oral dose of 800 mg over five days instead of their regular doses of 200 and 240 mg. Grade 4 neutropenia and thrombocytopenia developed in both patients within two weeks of the last lomustine dose. One of them was admitted to hospital because of febrile neutropenia. Neutropenia and thrombocytopenia were detected in the other patient when he was examined in the emergency room following a generalized convulsion...
November 2004: Tumori
https://read.qxmd.com/read/9403017/home-intravenous-antibiotic-treatment-for-febrile-episodes-in-immune-compromised-pediatric-patients
#19
JOURNAL ARTICLE
E Shemesh, I Yaniv, M Drucker, S Hadad, Y Goshen, J Stein, S Ash, S Fisher, R Zaizov
The purpose of this work was to assess the feasibility of home intravenous antibiotic treatment (HIAT) for febrile episodes in immune-compromised (neutropenic, splenectomized), low-risk pediatric patients. Thirty hematology-oncology patients who presented to our emergency room from January 1993 to January 1995 and who suffered from a febrile episode and were considered at low risk for septic complications were immediately discharged on HIAT. Patients were followed for at least 3 weeks after recovery. Patients and parents were retrospectively questioned about adverse effects and about their degree of satisfaction with home treatment...
February 1998: Medical and Pediatric Oncology
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