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diabetes probiotic

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https://www.readbyqxmd.com/read/28326881/the-effects-of-probiotic-supplementation-on-biomarkers-of-inflammation-oxidative-stress-and-pregnancy-outcomes-in-gestational-diabetes
#1
Bita Badehnoosh, Maryam Karamali, Mitra Zarrati, Mehri Jamilian, Fereshteh Bahmani, Maryam Tajabadi-Ebrahimi, Parvaneh Jafari, Elham Rahmani, Zatollah Asemi
OBJECTIVE: This study was designed to evaluate the effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes among subjects with gestational diabetes (GDM). METHODS: This randomized, double-blind, placebo-controlled clinical trial was done among 60 subjects with GDM who were not on oral hypoglycemic agents. Patients were randomly allocated to intake either probiotic capsule containing Lactobacillus acidophilus, Lactobacillus casei and Bifidobacterium bifidum (2 × 10(9) CFU/g each) (n = 30) or placebo (n = 30) for 6 weeks...
March 22, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28318686/probiotic-supplementation-for-management-of-cardiovascular-risk-factors-in-adults-with-type-ii-diabetes-a-systematic-review-and-meta-analysis
#2
Fatemeh Hendijani, Vajihe Akbari
BACKGROUND & AIMS: The effectiveness of probiotics in control of hypertension and dyslipidemia in diabetic patients remains unclear. Therefore, we systematically reviewed relevant data to elucidate the effects of probiotics on blood pressure and lipid profile of type 2 diabetic patients. METHODS: We searched PubMed, ISI Web of Knowledge, Scopus, The Cochrane Library, ClinicalTrials.gov, ProQuest Dissertations and Theses databases until May 2016. The primary outcomes were systolic blood pressure (SBP) and diastolic blood pressure (DBP), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG)...
February 24, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28317483/a-critical-review-of-bioactive-food-components-and-of-their-functional-mechanisms-biological-effects-and-health-outcomes
#3
Rosa Pérez-Gregorio, Jesús Simal-Gándara
BACKGROUND: Eating behaviours are closely related to some medical conditions potentially leading to death such as cancer, cardiovascular disease and diabetes. Healthy eating practices, maintaining a normal weight, and regular physical activity could prevent up to 80% of coronary heart disease, 90% of type-2 diabetes and one-third of all cancers[1]. METHOD: Over the last two decades, the food industry has invested much effort in research and development of healthier, more nutritious foods...
March 17, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28271466/intestinal-microbiota-in-type-2-diabetes-and-chronic-kidney-disease
#4
REVIEW
Alice Sabatino, Giuseppe Regolisti, Carmela Cosola, Loreto Gesualdo, Enrico Fiaccadori
PURPOSE OF THE REVIEW: Diabetes mellitus is a major cause of kidney disease [chronic kidney disease (CKD) and end-stage renal disease (ESRD)] and are both characterized by an increased risk of cardiovascular events. Diabetes and kidney disease are also commonly associated with a chronic inflammatory state, which is now considered a non-traditional risk factor for atherosclerosis. In the case of type 2 diabetes mellitus (T2DM), inflammation is mainly a consequence of visceral obesity, while in the case of CKD or ESRD patients on dialysis, inflammation is caused by multiple factors, classically grouped as dialysis-related and non-dialysis-related...
March 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28266114/interaction-of-lifestyle-behaviour-or-systemic-diseases-with-dental-caries-and-periodontal-diseases-consensus-report-of-group-2-of-the-joint-efp-orca-workshop-on-the-boundaries-between-caries-and-periodontal-diseases
#5
Iain L C Chapple, Philippe Bouchard, Maria Grazia Cagetti, Guglielmo Campus, Maria-Clotilde Carra, Fabio Cocco, Luigi Nibali, Philippe Hujoel, Marja L Laine, Peter Lingstrom, David J Manton, Eduardo Montero, Nigel Pitts, Hélène Rangé, Nadine Schlueter, Wim Teughels, Svante Twetman, Cor Van Loveren, Fridus Van der Weijden, Alexandre R Vieira, Andreas G Schulte
Periodontal diseases and dental caries are the most common diseases of humans and the main cause of tooth loss. Both diseases can lead to nutritional compromise and negative impacts upon self-esteem and quality of life. As complex chronic diseases, they share common risk factors, such as a requirement for a pathogenic plaque biofilm, yet they exhibit distinct pathophysiologies. Multiple exposures contribute to their causal pathways, and susceptibility involves risk factors that are inherited (e.g. genetic variants), and those that are acquired (e...
March 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28252037/a-proliferative-probiotic-bifidobacterium-strain-in-the-gut-ameliorates-progression-of-metabolic-disorders-via-microbiota-modulation-and-acetate-elevation
#6
Ryo Aoki, Kohei Kamikado, Wataru Suda, Hiroshi Takii, Yumiko Mikami, Natsuki Suganuma, Masahira Hattori, Yasuhiro Koga
The gut microbiota is an important contributor to the worldwide prevalence of metabolic syndrome (MS), which includes obesity and diabetes. The anti-MS effects exerted by Bifidobacterium animalis ssp. lactis GCL2505 (BlaG), a highly proliferative Bifidobacterium strain in the gut, and B. longum ssp. longum JCM1217(T) (BloJ) were comparatively examined. BlaG treatment reduced visceral fat accumulation and improved glucose tolerance, whereas BloJ had no effect on these parameters. Gut microbial analysis revealed that BlaG exerted stronger effects on the overall bacterial structure of the gut microbiota than BloJ, including enrichment of the genus Bifidobacterium...
March 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28237613/effects-of-probiotics-supplement-in-patients-with-type-2-diabetes-mellitus-a-meta-analysis-of-randomized-trials
#7
REVIEW
Yi-Meng Hu, Feng Zhou, Yin Yuan, Yan-Cheng Xu
BACKGROUND AND OBJECTIVE: To objectively evaluate the effects of probiotics supplement on glycemic control and lipid metabolism in patients with type 2 diabetes mellitus (T2DM). MATERIAL AND METHODS: The randomized controlled trials (RCTs) with regard to the probiotics or synbiotics for the treatment of T2DM were collected through retrieving 5 databases from their establishment to March 2016. After study selection, quality assessment and data extraction were performed by 2 authors independently; and STATA software was used for statistical analysis...
February 22, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28139139/roseburia-spp-a-marker-of-health
#8
Zohreh Tamanai-Shacoori, Imen Smida, Latifa Bousarghin, Olivier Loreal, Vincent Meuric, Shao Bing Fong, Martine Bonnaure-Mallet, Anne Jolivet-Gougeon
The genus Roseburia consists of obligate Gram-positive anaerobic bacteria that are slightly curved, rod-shaped and motile by means of multiple subterminal flagella. It includes five species: Roseburia intestinalis, R. hominis, R. inulinivorans, R. faecis and R. cecicola. Gut Roseburia spp. metabolize dietary components that stimulate their proliferation and metabolic activities. They are part of commensal bacteria producing short-chain fatty acids, especially butyrate, affecting colonic motility, immunity maintenance and anti-inflammatory properties...
February 2017: Future Microbiology
https://www.readbyqxmd.com/read/28120718/nutraceuticals-and-dietary-supplements-to-improve-quality-of-life-and-outcomes-in-heart-failure-patients
#9
Arrigo Fg Cicero, Alessandro Colletti
BACKGROUND: Heart failure (HF) is a complex clinical syndrome that can result from any structural or functional cardiac disorder that impairs the ability of the ventricle to fill or eject blood. It represents a major public health issue, with a prevalence of over 23 million worldwide. The lifetime risk of developing HF is one in five and the most important risk factors identified are ischemic heart disease, hypertension, smoking, obesity and diabetes. Preventive approaches are based on improvements of lifestyle, associated with pharmacological therapy...
January 24, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28109835/gut-microbiota-a-player-in-aging-and-a-target-for-anti-aging-intervention
#10
REVIEW
Alexander M Vaiserman, Alexander K Koliada, Francesco Marotta
Aging-associated alterations in composition, diversity and functional features of intestinal microbiota are well-described in the modern literature. They are suggested to be caused by an age-related decline in immune system functioning (immunosenescence) and a low-grade chronic inflammation (inflammaging), which accompany many aging-associated pathologies. The microbiota-targeted dietary and probiotic interventions have been shown to favorably affect the host health and aging by an enhancement of antioxidant activity, improving immune homeostasis, suppression of chronic inflammation, regulation of fat deposition and metabolism and prevention of insulin resistance...
January 18, 2017: Ageing Research Reviews
https://www.readbyqxmd.com/read/28104104/role-of-gastrointestinal-microbiota-on-kidney-injury-and-the-obese-condition
#11
REVIEW
Keerati Wanchai, Anchalee Pongchaidecha, Varanuj Chatsudthipong, Siriporn C Chattipakorn, Nipon Chattipakorn, Anusorn Lungkaphin
Obesity is associated with kidney disease, probably due to obesity-mediated inflammation, podocyte injury and oxidative stress in the kidney It is also linked to other diseases, for example, diabetes and hypertension, which are associated with the development and progression of chronic kidney disease. Interestingly, gastrointestinal dysbiosis has been demonstrated in cases of obesity with the development and progression of kidney disease. Thus, modification of gastrointestinal microbiota using probiotics or prebiotics or both to improve the balance of bacterial flora is a potential approach for the management of obesity-associated kidney disease...
January 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28102115/can-probiotics-modulate-human-disease-by-impacting-intestinal-barrier-function
#12
Peter A Bron, Michiel Kleerebezem, Robert-Jan Brummer, Patrice D Cani, Annick Mercenier, Thomas T MacDonald, Clara L Garcia-Ródenas, Jerry M Wells
Intestinal barrier integrity is a prerequisite for homeostasis of mucosal function, which is balanced to maximise absorptive capacity, while maintaining efficient defensive reactions against chemical and microbial challenges. Evidence is mounting that disruption of epithelial barrier integrity is one of the major aetiological factors associated with several gastrointestinal diseases, including infection by pathogens, obesity and diabetes, necrotising enterocolitis, irritable bowel syndrome and inflammatory bowel disease...
January 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28096139/potential-health-benefits-of-combining-yogurt-and-fruits-based-on-their-probiotic-and-prebiotic-properties
#13
REVIEW
Melissa Anne Fernandez, André Marette
Fruit and yogurt have been identified individually as indicators of healthy dietary patterns. Fruits are relatively low in energy density and are an excellent source of antioxidants and prebiotic fibers and polyphenols, which can promote digestive health. Yogurt, on the other hand, is a nutrient-dense food that is a good source of dairy protein, calcium, magnesium, vitamin B-12, conjugated linoleic acid, and other key fatty acids. In addition, it contains beneficial bacterial cultures, making it a potential source of probiotics...
January 2017: Advances in Nutrition
https://www.readbyqxmd.com/read/28086768/probiotic-mixture-improves-fatty-liver-disease-by-virtue-of-its-action-on-lipid-profiles-leptin-and-inflammatory-biomarkers
#14
Hessah Mohammed Al-Muzafar, Kamal Adel Amin
BACKGROUND: A high fat diet has an essential role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). This condition is characterized by hepatic fat accumulation (steatosis) and is associated with obesity, diabetes, and fibrosis or cirrhosis of the liver. Probiotics may be useful in the treatment of steatosis. This study examined the effects of an ingested probiotic formulation on the lipid profiles, liver functions, leptin levels, and inflammatory marker levels of rats with NAFLD that had been induced via high fat and sucrose diet (HFSD)...
January 13, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28069054/the-effect-of-a-novel-probiotic-on-metabolic-biomarkers-in-adults-with-prediabetes-and-recently-diagnosed-type-2-diabetes-mellitus-study-protocol-for-a-randomized-controlled-trial
#15
Talia Palacios, Luis Vitetta, Samantha Coulson, Claire D Madigan, Gareth S Denyer, Ian D Caterson
BACKGROUND: Shifts in the gastrointestinal microbiome have been shown to contribute to the progression of metabolic diseases including prediabetes and type 2 diabetes mellitus. Research suggests that in-vivo modulation of the gut microbiome by specific probiotic microorganisms may improve insulin sensitivity and blood sugar management, preventing or delaying the development of type 2 diabetes mellitus. However, further research is needed to understand the effect of probiotics as a therapy for the treatment of metabolic diseases...
January 9, 2017: Trials
https://www.readbyqxmd.com/read/28042926/the-potential-impact-of-gut-microbiota-on-your-health-current-status-and-future-challenges
#16
Stitaya Sirisinha
Our health and probably also our behaviors and mood depend not only on what we eat or what we do (lifestyle behaviors), but also on what we host. It is well established for decades that all vertebrates including humans are colonized by a wide array of bacteria, fungi, eukaryotic parasites and viruses, and that, at steady state (homeostasis), this community of microbes establishes a friendly mutual relationship with the host. The term microbiota was originally meant to represent an ecological community of commensals and potentially pathogenic microbes that live within our bodies, but it is now used interchangeably with the term microbiome which was initially meant to represent a collective genome of the microbiota...
December 2016: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28029082/probiotics-in-curing-allergic-and-inflammatory-conditions-research-progress-and-futuristic-vision
#17
Kuldeep Dhama, Shyma K Latheef, Ashok Kumar Munjal, Rekha Khandia, Hari Abdul Samad, Hafiz M N Iqbal, Sunil K Joshi
BACKGROUND: Probiotics constitute the viable and beneficial microbes, which offer a dietary means to sustain the balance of gastro-intestinal (GI) microflora. Owing to their multiple health benefits, these have recently gained wide attention among researchers for exploring their potential in safeguarding the health of humans and animals. Probiotics could also modulate host-immune responses, thereby help in counteracting the immunological dysfunctions. Probiotics can inhibit the systemic invasion of pathogens entering through the GI mucosa/ oral cavity and have been found to possess effective prophylactic and therapeutic utilities against various infectious pathogens as well as non-infectious diseases and disorders...
December 26, 2016: Recent Patents on Inflammation & Allergy Drug Discovery
https://www.readbyqxmd.com/read/28009106/metabolic-effects-of-lactobacillus-reuteri-dsm-17938-in-people-with-type-2-diabetes-a-randomized-controlled-trial
#18
Reza Mobini, Valentina Tremaroli, Marcus Ståhlman, Fredrik Karlsson, Max Levin, Maria Ljungberg, Maja Sohlin, Heléne Bertéus Forslund, Rosie Perkins, Fredrik Bäckhed, Per-Anders Jansson
AIMS: To investigate the metabolic effects of 12-week oral supplementation with Lactobacillus reuteri DSM 17938 in patients with type 2 diabetes on insulin therapy. MATERIALS AND METHODS: In a double-blind trial, we randomized 46 people with type 2 diabetes to placebo or a low (10(8)  CFU/d) or high dose (10(10)  CFU/d) of L. reuteri DSM 17938 for 12 weeks. The primary endpoint was the effect of supplementation on glycated haemoglobin (HbA1c). Secondary endpoints were insulin sensitivity (assessed by glucose clamp), liver fat content, body composition, body fat distribution, faecal microbiota composition and serum bile acids...
December 23, 2016: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28008783/lactobacillus-rhamnosus-ncdc17-ameliorates-type-2-diabetes-by-improving-gut-function-oxidative-stress-and-inflammation-in-high-fat-diet-fed-and-streptozotocintreated-rats
#19
S Singh, R K Sharma, S Malhotra, R Pothuraju, U K Shandilya
Restoration of dysbiosed gut microbiota through probiotic may have profound effect on type 2 diabetes. In the present study, rats were fed high fat diet (HFD) for 3 weeks and injected with low dose streptozotocin to induce type 2 diabetes. Diabetic rats were then fed Lactobacillus rhamnosus NCDC 17 and L. rhamnosus GG with HFD for six weeks. L. rhamnosus NCDC 17 improved oral glucose tolerance test, biochemical parameters (fasting blood glucose, plasma insulin, glycosylated haemoglobin, free fatty acids, triglycerides, total cholesterol, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol), oxidative stress (thiobarbituric acid reactive substance and activities of catalase, superoxide dismutase and glutathione peroxidase in blood and liver), bifidobacteria and lactobacilli in cecum, expression of glucagon like peptide-1 producing genes in cecum, and adiponection in epididymal fat, while decreased propionate proportions (%) in caecum, and expression of tumour necrosis factor-α and interlukin-6 in epididymal fat of diabetic rats as compared to diabetes control group...
December 23, 2016: Beneficial Microbes
https://www.readbyqxmd.com/read/28001147/effects-of-weight-loss-using-supplementation-with-lactobacillus-strains-on-body-fat-and-medium-chain-acylcarnitines-in-overweight-individuals
#20
Minkyung Kim, Minjoo Kim, Miso Kang, Hye Jin Yoo, Min Sun Kim, Young-Tae Ahn, Jae-Hun Sim, Sun Ha Jee, Jong Ho Lee
Our previous study showed that supplementation with a combination of Lactobacillus curvatus (L. curvatus) HY7601 and Lactobacillus plantarum (L. plantarum) KY1032 reduced the body weight, body fat percentage, body fat mass and L1 subcutaneous fat area in overweight subjects. We aimed to evaluate whether the changes in adiposity after supplementation with Lactobacillus strains were associated with metabolic intermediates. A randomized, double-blind, placebo-controlled study was conducted on 66 non-diabetic and overweight individuals...
December 21, 2016: Food & Function
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