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https://www.readbyqxmd.com/read/29159751/septal-and-turbinate-surgery-is-overnight-essential
#1
Ana Sousa Menezes, Joana R Guimarães, Miguel Breda, Vicente Vieira, Luís Dias
INTRODUCTION: The performance of septoplasty and turbinate surgery in an outpatient basis is an increasingly established practice, although is still a controversial topic. METHODS: Retrospective analysis of 227 patients who underwent septoplasty ± inferior and/or middle turbinoplasty. Demographic, clinical, surgical, and anesthetic data were collected. Our primary outcomes were rates of perioperative complications, prolongation of hospital stay (PHS), unexpected hospital revisits (UHR), or readmissions within 30 days of surgery...
November 20, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28772011/brain-molecular-changes-and-behavioral-alterations-induced-by-propofol-anesthesia-exposure-in-peripubertal-rats
#2
Željko Pavković, Kosara Smiljanić, Selma Kanazir, Desanka Milanović, Vesna Pešić, Sabera Ruždijić
BACKGROUND: Propofol is commonly used in modern anesthesiology. Some findings suggest that it is highly addictive. AIM: In this study it was examined whether propofol anesthesia exposure was able to induce behavioral alterations and brain molecular changes already described in addictive drug usage in peripubertal rats, during the onset of mid/periadolescence as a developmental period with increasing vulnerability to drug addiction. METHODS: The expression of D1 dopamine receptor, a dopamine, and cAMP-regulated phosphoprotein with a Mr 32 000; Ca(2+) /calmodulin-dependent protein kinase IIα; and Finkel-Biskis-Jinkins murine osteosarcoma viral oncogene homolog-B was examined in peripubertal rats 4, 24, and 48 hour after propofol anesthesia exposure by Western blot and immunohistochemistry...
September 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28413287/de-addiction-a-new-risk-for-anesthesia
#3
Gurkaran Kaur, Seema Jindal, Gurpreet Kaur
No abstract text is available yet for this article.
January 2017: Journal of Anaesthesiology, Clinical Pharmacology
https://www.readbyqxmd.com/read/28333299/bilateral-breast-reduction-without-opioid-analgesics-a-comparative-study
#4
Fereydoun Don Parsa, Justin Cheng, Brad Stephan, Nikki Castel, Leslie Kim, Daniel Murariu, Alan A Parsa
Background: Breast reduction has traditionally been performed under general anesthesia with adjunct opioid use. However, opioids are associated with a wide variety of adverse effects, including nausea, vomiting, constipation, postoperative sedation, dizziness, and addiction. Objectives: This study compares bilateral breast reduction using a multimodal opioid-free pain management regimen vs traditional general anesthesia with adjunct opioids. Methods: A total of 83 female patients were enrolled in this study...
September 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28257514/analysis-of-print-news-media-framing-of-ketamine-treatment-in-the-united-states-and-canada-from-2000-to-2015
#5
Melvyn W B Zhang, Ying X Hong, Syeda F Husain, Keith M Harris, Roger C M Ho
OBJECTIVES: There are multifaceted views on the use of ketamine, a potentially addictive substance, to treat mental health problems. The past 15 years have seen growing media coverage of ketamine for medical and other purposes. This study examined the print news media coverage of medical and other uses of ketamine in North America to determine orientations and trends over time. METHODS: Print newspaper coverage of ketamine from 2000 to 2015 was reviewed, resulting in 43 print news articles from 28 North American newspapers...
2017: PloS One
https://www.readbyqxmd.com/read/28251524/pain-management-of-patients-with-substance-abuse-in-the-ambulatory-setting
#6
REVIEW
Nalini Vadivelu, Alice M Kai, Vijay Kodumudi, Richard Zhu, Roberta Hines
PURPOSE OF REVIEW: Abuse of illicit substances and prescription opioids is a growing problem that presents challenges for pain management in the inpatient and outpatient setting. With future patient care models shifting toward shorter hospital stays and more same-day surgeries, it is crucial that clinicians learn to manage this patient population and strike a balance between the overtreatment of pain that can subsequently worsen tolerance and addiction, and the undertreatment of pain that can lead to pseudoaddiction...
February 2017: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/27928715/the-impaired-anesthesiologist-what-you-should-know-about-substance-abuse
#7
Stefan T Samuelson, Ethan O Bryson
PURPOSE: Despite our considerable experience with the problem of addiction in our specialty, most anesthesia care providers don't know how to identify or help an impaired colleague. The purpose of this article to provide sufficient information on substance use disorder (SUD) to aid in its identification amongst colleagues and to assist in its management. PRINCIPAL FINDINGS: Depending on the region, 10-15% of the general population is prone to developing a SUD and will abuse drugs or alcohol at some point in their life...
February 2017: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/27790356/moderate-hypothermia-and-its-effects-in-reducing-the-applied-dose-of-anesthetics-for-patients-with-opium-dependence-in-cardiac-surgery-a-randomized-controlled-trial
#8
Reza Jalaian Taghadomi, Ebrahim Golmakani, Kambiz Alizadeh, Behrooz Mottahedi, Ali Rahdari, Shima Sheybani
BACKGROUND: An increasing number of patients addicted to opium are experiencing awareness during coronary artery bypass surgery (CABG) as a result of tolerance to anesthetics. OBJECTIVES: This research was primarily intended to determine the potential diminishing effects of moderate hypothermia on anesthetic dosage and recall of anesthesia during the procedure. METHODS: In this double-blind randomized controlled trial, a total of 80 CABG candidates with known addiction to opium were divided into two groups: one normothermic (N) and the other moderately hypothermic (H), both undergoing induction as well as close monitoring from September 2014 to January 2016...
September 2016: Electronic Physician
https://www.readbyqxmd.com/read/27579281/the-cortisol-level-and-its-relationship-with-depression-stress-and-anxiety-indices-in-chronic-methamphetamine-dependent-patients-and-normal-individuals-undergoing-inguinal-hernia-surgery
#9
Bijan Pirnia, Fatemeh Givi, Rasool Roshan, Kambiz Pirnia, Ali Akbar Soleimani
BACKGROUND: Stimulants addition and abuse can cause some functional and morphological changes in the normal function of glands and hormones. Methamphetamine as an addictive stimulant drug affects the Hypothalamic- pituitary-adrenal (HPA) axis and consequently makes some changes in the psychological state of the drug users. The present study aims to examine the relationship between plasma levels of cortisol with depression, stress and anxiety symptoms in chronic methamphetamine-dependent patients and normal individuals who have undergone the inguinal hernia surgery...
2016: Medical Journal of the Islamic Republic of Iran
https://www.readbyqxmd.com/read/27564553/mechanisms-for-research-support
#10
REVIEW
Philipp Houck, Manon Hache, Jennifer Busse
During the second day of the Pediatric Anesthesia NeuroDevelopment Assessment (PANDA) symposium 2016, 3 invited speakers focused on future directions for the PANDA group. This session, entitled "The Way Forward," included 3 talks on how other groups have organized through public-private partnerships (ACTTION), obtained NIH funding, and how to better communicate a research message. Dr Robert H. Dworkin spoke on the mission of the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities and Networks (ACTTION), which is a public-private partnership with the United States Food and Drug Administration that pushes forward research related to pain and analgesics...
October 2016: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/27460517/parental-smoking-and-children-undergoing-anesthesia-is-there-a-role-for-pediatric-hospitals-in-smoking-cessation
#11
MULTICENTER STUDY
Krista Niedermeier, Cynthia S Selleck
PURPOSE: Pediatric hospitals within the Children's Hospital Association were surveyed to determine their tobacco cessation efforts for parents/patients. DESIGN AND METHODS: Electronic surveys were sent to 75 anesthesia providers and/or preoperative surgery specialists at 41 facilities. RESULTS: A total of 52 completed surveys were returned. The majority (97%) of facilities were smoke-free, and 68% included preoperative questions about parental smoking and secondhand smoke (SHS) exposure...
October 2016: Journal for Specialists in Pediatric Nursing: JSPN
https://www.readbyqxmd.com/read/27378852/social-isolation-blunted-the-response-of-mesocortical-dopaminergic-neurons-to-chronic-ethanol-voluntary-intake
#12
Valeria Lallai, Letizia Manca, Laura Dazzi
Previous studies have shown that stress can increase the response of mesolimbic dopaminergic neurons to acute administration of drugs of abuse included ethanol. In this study, we investigated the possible involvement of the mesocortical dopaminergic pathway in the development of ethanol abuse under stress conditions. To this aim we trained both socially isolated (SI) and group housed (GH) rats to self administer ethanol which was made available only 2 ha day (from 11:00 to 13:00 h). Rats have been trained for 3 weeks starting at postnatal day 35...
2016: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/27343782/evaluation-of-spinal-anesthesia-blockade-time-with-0-5-hyperbaric-bupivacaine-with-or-without-sufentanil-in-chronic-opioid-users-a-randomized-clinical-trial
#13
RANDOMIZED CONTROLLED TRIAL
Mostafa Sadeghi, Reza Atef Yekta, Omid Azimaraghi, Gilda Barzin, Ali Movafegh
OBJECTIVE: The primary outcome of this study was to evaluate the effect of adding sufentanil to hyperbaric bupivacaine on duration of sensory blockade of spinal anesthesia in chronic opioid users in comparison with non-addicts. METHODS: Sixty patients scheduled for orthopedic surgery under spinal anesthesia were allocated into four groups: group 1 (no history of opium use who received intrathecal hyperbaric bupivacaine along with 1mL saline as placebo); group 2 (no history of opium use who received intrathecal bupivacaine along with 1mL sufentanil [5μg]); group 3 (positive history of opium use who received intrathecal bupivacaine along with 1mL saline as placebo) and group 4 (positive history of opium use who received intrathecal bupivacaine along with 1mL sufentanil [5μg])...
July 2016: Brazilian Journal of Anesthesiology
https://www.readbyqxmd.com/read/27321205/neural-response-differences-in-the-rat-primary-auditory-cortex-under-anesthesia-with-ketamine-versus-the-mixture-of-medetomidine-midazolam-and-butorphanol
#14
Hisayuki Osanai, Takashi Tateno
Anesthesia affects central auditory processing. However, it is unclear to what extent the choice of anesthetic agent affects neural responses to sound stimulation. A mixture of three anesthetics (medetomidine, midazolam and butorphanol; MMB) was recently developed as an alternative to ketamine owing to the latter's addictive potential, yet the effect of this combination of anesthetics on neural responses is not known. Here, we compared the spontaneous activity, tuning properties and temporal responses of primary auditory cortical neurons under these two anesthetic conditions, using electrophysiological and flavoprotein autofluorescence imaging methods...
September 2016: Hearing Research
https://www.readbyqxmd.com/read/27200514/changes-in-potassium-concentration-during-opioid-antagonist-induction-comparison-of-two-randomized-clinical-trials
#15
COMPARATIVE STUDY
Robertas Badaras, Tomas Jovaisa, Sarunas Judickas, Juozas Ivaskevicius
OBJECTIVES: Opioid antagonist induction under general anesthesia or heavy sedation has been criticized due to its associated morbidity and mortality. Information on the potential causes of these complications is limited. We aimed to compare electrolyte concentration changes during rapid opioid antagonist induction under general anesthesia and conscious sedation, and to find out whether these changes are associated with cardiovascular complications. METHODS: We used a pooled database analysis of 2 prospective randomized controlled clinical trials carried out in Lithuania between 2002 and 2014...
July 2016: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/27155781/-evaluation-of-spinal-anesthesia-blockade-time-with-0-5-hyperbaric-bupivacaine-with-or-without-sufentanil-in-chronic-opioid-users-a-randomized-clinical-trial
#16
Mostafa Sadeghi, Reza Atef Yekta, Omid Azimaraghi, Gilda Barzin, Ali Movafegh
OBJECTIVE: The primary outcome of this study was to evaluate the effect of adding sufentanil to hyperbaric bupivacaine on duration of sensory blockade of spinal anesthesia in chronic opioid users in comparison with non-addicts. METHODS: Sixty patients scheduled for orthopedic surgery under spinal anesthesia were allocated into four groups: group 1 (no history of opium use who received intrathecal hyperbaric bupivacaine along with 1mL saline as placebo); group 2 (no history of opium use who received intrathecal bupivacaine along with 1mL sufentanil [5μg]); group 3 (positive history of opium use who received intrathecal bupivacaine along with 1mL saline as placebo) and group 4 (positive history of opium use who received intrathecal bupivacaine along with 1mL sufentanil [5μg])...
July 2016: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/27110524/intrathecal-dexmedetomidine-and-fentanyl-as-adjuvant-to-bupivacaine-on-duration-of-spinal-block-in-addicted-patients
#17
Farhad Safari, Reza Aminnejad, Seyed Amir Mohajerani, Farshad Farivar, Kamran Mottaghi, Hasan Safdari
BACKGROUND: Addicted patients have innate tolerance to local anesthetics in both neuraxial and peripheral blocks. Dexmedetomidine (Dex) is a highly selective α2 adrenergic receptor agonist used as additive to increase quality and duration of peripheral nerve blocks. OBJECTIVES: The current study aimed to compare the effect of dexmedetomidine and fentanyl additives on bupivacaine to prolong the duration of block and minimizing side effects. PATIENTS AND METHODS: Patients were candidates for elective surgery less than three hours of lower abdomen or lower extremities surgeries...
February 2016: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/26885357/what-is-the-main-reason-for-reduction-in-duration-of-action-of-local-anesthetics-used-for-spinal-anesthesia-in-opium-addicted-patients
#18
Samaneh Kouzehgaran, Amir Saber-Tanha
No abstract text is available yet for this article.
July 2015: Addiction & Health
https://www.readbyqxmd.com/read/26879874/new-pain-management-options-for-the-surgical-patient-on-methadone-and-buprenorphine
#19
REVIEW
Sudipta Sen, Sailesh Arulkumar, Elyse M Cornett, Julie A Gayle, Ronda R Flower, Charles J Fox, Alan D Kaye
Perioperative management of patients receiving opioid addiction therapy presents a unique challenge for the anesthesiologist. The goal of pain management in this patient population is to effectively manage postoperative pain, to improve patient satisfaction and outcomes, and to reduce the cost of health care. Multimodal analgesics, including nonsteroid anti-inflammatory drugs, intravenous acetaminophen, gabapentanoid agents, and low-dose ketamine infusions, have been used to improve postoperative pain and to reduce postoperative opioid use...
March 2016: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/26473101/effects-of-clonidine-premedication-on-intraoperative-blood-loss-in-patients-with-and-without-opium-addiction-during-elective-femoral-fracture-surgeries
#20
Davood Ommi, Houman Teymourian, Alireza Zali, Farzad Ashrafi, Morteza Jabbary Moghaddam, Alireza Mirkheshti
BACKGROUND: Opium is an addictive agent and one of the most common narcotics With great challenges of intraoperative hemodynamic instabilities. OBJECTIVES: The current study aimed to assess the effects of clonidine on intraoperative blood loss in patients with and without opium addiction in femoral fracture surgeries. PATIENTS AND METHODS: In a randomized clinical trial, 160 candidates for elective femoral fracture operations under general anesthesia were divided into four groups of 40 subjects: group 1 (placebo 1), subjects without addiction received placebo 90 minutes before the operation; group 2 (placebo 2), patients with opium addiction received placebo as group 1; group 3 (Clonidine 1), patients without addiction received clonidine 90 minutes before the operation and group 4 (Clonidine 2), patients with opium addiction received clonidine as premedication...
August 2015: Anesthesiology and Pain Medicine
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