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Probiotic microbiota

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https://www.readbyqxmd.com/read/28217701/gut-microbiota-and-oxalate-homeostasis
#1
Marguerite Hatch
This perspective focuses on how the gut microbiota can impact urinary oxalate excretion in the context of hyperoxaluria, a major risk factor in kidney stone disease. In the genetic disease of Primary Hyperoxaluria Type 1 (PH1), an increased endogenous production of oxalate, due to a deficiency of the liver enzyme alanine-glyoxylate aminotransferase (AGT), results in hyperoxaluria and oxalate kidney stones. The constant elevation in urinary oxalate in PH1 patients ultimately leads to tissue deposition of oxalate, renal failure and death and the only known cure for PH1 is a liver or liver-kidney transplant...
January 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28215759/impact-of-ageing-and-a-synbiotic-on-the-immune-response-to-seasonal-influenza-vaccination-a-randomised-controlled-trial
#2
Sumia Enani, Agnieszka Przemska-Kosicka, Caroline E Childs, Catherine Maidens, Honglin Dong, Lorenza Conterno, Kieran Tuohy, Susan Todd, Margot Gosney, Parveen Yaqoob
BACKGROUND & AIMS: Ageing increases risk of respiratory infections and impairs the response to influenza vaccination. Pre- and pro-biotics offer an opportunity to modulate anti-viral defenses and the response to vaccination via alteration of the gut microbiota. This study investigated the effect of a novel probiotic, Bifidobacterium longum bv. infantis CCUG 52486, combined with a prebiotic, gluco-oligosaccharide, on the B and T cell response to seasonal influenza vaccination in young and older subjects ...
January 28, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28215310/review-of-the-mechanisms-of-probiotic-actions-in-the-prevention-of-colorectal-cancer
#3
REVIEW
Sandra A Dos Reis, Lisiane L da Conceição, Nathane P Siqueira, Damiana D Rosa, Letícia L da Silva, Maria do Carmo G Peluzio
The purpose of this review is to discuss the potential mechanisms of probiotics action in colorectal cancer prevention. In this regard, the composition of the intestinal microbiota is considered as an important risk factor in the development of colorectal cancer, and probiotics are able to positively modulate the composition of this microbiota. Studies have shown that the regular consumption of probiotics could prevent the development of colorectal cancer. In this respect, in vitro and experimental studies suggest some potential mechanisms responsible for this anticarcinogenic action...
January 2017: Nutrition Research
https://www.readbyqxmd.com/read/28215066/how-to-modulate-gut-microbiota-diet-pre-probiotics-or-antibiotics
#4
Francesca R Ponziani, Cecilia Binda, Antonio Gasbarrini
The gut microbiota is involved in the maintenance of humans' health and its alterations have been associated to several intestinal and extra intestinal disorders. For this reason, there is increasing interest on gut microbiota modulation as both a preventive strategy or as a therapeutic option in different gastrointestinal, hepatic and systemic diseases. Many studies have tried to find out the impact of diet, prebiotic, probiotic and antibiotics on gut microbiota composition and function, obtaining very heterogeneous and sometimes conflicting results, especially as regards the effect on clinical outcomes...
February 17, 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28212267/effects-of-dietary-yogurt-on-the-healthy-human-gastrointestinal-gi-microbiome
#5
Daniel J Lisko, G Patricia Johnston, Carl G Johnston
The gastrointestinal (GI) tract performs key functions that regulate the relationship between the host and the microbiota. Research has shown numerous benefits of probiotic intake in the modulation of immune responses and human metabolic processes. However, unfavorable attention has been paid to temporal changes of the microbial composition and diversity of the GI tract. This study aimed to investigate the effects of yogurt consumption on the GI microbiome bacteria community composition, structure and diversity during and after a short-term period (42 days)...
February 15, 2017: Microorganisms
https://www.readbyqxmd.com/read/28210076/potential-role-of-the-gut-microbiota-in-synthetic-torpor-and-therapeutic-hypothermia
#6
REVIEW
Claudia Sisa, Silvia Turroni, Roberto Amici, Patrizia Brigidi, Marco Candela, Matteo Cerri
Therapeutic hypothermia is today used in several clinical settings, among them the gut related diseases that are influenced by ischemia/reperfusion injury. This perspective paved the way to the study of hibernation physiology, in natural hibernators, highlighting an unexpected importance of the gut microbial ecosystem in hibernation and torpor. In natural hibernators, intestinal microbes adaptively reorganize their structural configuration during torpor, and maintain a mutualistic configuration regardless of long periods of fasting and cold temperatures...
January 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28203450/the-effect-of-probiotic-yogurt-on-constipation-in-pregnant-women-a-randomized-controlled-clinical-trial
#7
Mojgan Mirghafourvand, Aziz Homayouni Rad, Sakineh Mohammad Alizadeh Charandabi, Zahra Fardiazar, Kolsoum Shokri
BACKGROUND: Probiotics can alter the colonic microbiota and might improve bowel function. OBJECTIVES: The aim of this study was to evaluate the effect of the consumption of yogurt, enriched with Bifidobacterium and Lactobacillus 4.8 × 10(10) (CFU) on the symptoms of constipated pregnant women. MATERIALS AND METHODS: This triple-blind randomized controlled trial was conducted on 60 constipated pregnant women who were diagnosed by the ROME III criteria in Tabriz, Iran from December 2014 to July 2015...
November 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/28201936/effects-of-lactobacillus-casei-and-enterococcus-faecalis-on-growth-performance-immune-function-and-gut-microbiota-of-suckling-piglets
#8
Chaoqi Liu, Qun Zhu, Juan Chang, Qingqiang Yin, Andong Song, Zhentian Li, Erzhu Wang, Fushan Lu
This study was carried out to investigate the effects of orally administrated Lactobacillus casei and Enterococcus faecalis on performance, immune function and gut microbiota of suckling piglets. Neonatal piglets (n = 120) were randomly assigned to 4 groups, with 30 suckling piglets in each group. The piglets were from 15 litters, one male and one female piglet were selected for each group in each litter. The Control group was administrated with normal saline, the other groups with L. casei or E. faecalis or a combination of L...
April 2017: Archives of Animal Nutrition
https://www.readbyqxmd.com/read/28199741/melatonin-prevents-obesity-through-modulation-of-gut-microbiota-in-mice
#9
Pengfei Xu, Jialin Wang, Fan Hong, Sheng Wang, Xi Jin, Tingting Xue, Li Jia, Yonggong Zhai
Excess weight and obesity are severe public health threats worldwide. Recent evidence demonstrates that gut microbiota dysbiosis contributes to obesity and its comorbidities. The body weight-reducing and energy balancing effects of melatonin have been reported in several studies, but to date, no investigations toward examining whether the beneficial effects of melatonin are associated with gut microbiota have been carried out. In this study, we show that melatonin reduces body weight, liver steatosis, and low-grade inflammation as well as improving insulin resistance in high fat diet (HFD)-fed mice...
February 15, 2017: Journal of Pineal Research
https://www.readbyqxmd.com/read/28195067/the-effect-of-short-term-treatment-with-probiotic-vsl-3-on-various-clinical-and-biochemical-parameters-in-patients-with-liver-cirrhosis
#10
W Marlicz, E Wunsch, M Mydlowska, M Milkiewicz, K Serwin, M Mularczyk, P Milkiewicz, J Raszeja-Wyszomirska
The evidence is mounting that alterations of innate immunity and gut microbiota contribute to chronic liver disease and its complications. Modulation of intestinal microbiota is an emerging therapeutic strategy in hepatology. Probiotics through modulation of intestinal milieu have the potential to affect the course of liver disease. The data concerning the influence of probiotics on various plasma molecules and compounds involved in the pathogenesis of hyperdynamic circulatory state in liver cirrhosis is still not confluent and require further evaluation...
December 2016: Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society
https://www.readbyqxmd.com/read/28194099/gut-to-brain-dysbiosis-mechanisms-linking-western-diet-consumption-the-microbiome-and-cognitive-impairment
#11
REVIEW
Emily E Noble, Ted M Hsu, Scott E Kanoski
Consumption of a Western Diet (WD) that is high in saturated fat and added sugars negatively impacts cognitive function, particularly mnemonic processes that rely on the integrity of the hippocampus. Emerging evidence suggests that the gut microbiome influences cognitive function via the gut-brain axis, and that WD factors significantly alter the proportions of commensal bacteria in the gastrointestinal tract. Here we review mechanisms through which consuming a WD negatively impacts neurocognitive function, with a particular focus on recent evidence linking the gut microbiome with dietary- and metabolic-associated hippocampal impairment...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28188340/development-and-validation-of-a-new-dynamic-in-vitro-model-of-the-piglet-colon-pigutivm-application-to-the-study-of-probiotics
#12
Mickaël Alain Fleury, Olivier Le Goff, Sylvain Denis, Frédérique Chaucheyras-Durand, Eric Jouy, Isabelle Kempf, Monique Alric, Stéphanie Blanquet-Diot
For ethical, technical, regulatory, and cost reasons, in vitro methods are increasingly used as an alternative to in vivo experimentations. The aim of the present study was to validate, according to in vivo data in living animals, a new in vitro model of the piglet colon, the PigutIVM, under both control conditions and antibiotic disturbance by the widely used colistin. The PigutIVM reproduces the main biotic and abiotic parameters of the piglet colon: temperature, pH, retention time, supply of ileal effluents, complex, and metabolically active microbiota and self-maintained anaerobiosis...
February 10, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28185664/review-of-the-role-of-probiotics-in-gastrointestinal-diseases-in-adults
#13
Juan José Sebastián Domingo
BACKGROUND: Probiotics may act as biological agents that modify the intestinal microbiota and certain cytokine profiles, which can lead to an improvement in certain gastrointestinal diseases. OBJECTIVES: To conduct a review of the evidence of the role of probiotics in certain gastrointestinal diseases in adults. SEARCH METHODS: Review conducted using appropriate descriptors, filters and limits in the PubMed database (MEDLINE). SELECTION CRITERIA: The MeSH terms used were Probiotics [in the title] AND Gastrointestinal Diseases, with the following limits or filters: Types of study: Systematic Reviews, Meta-Analysis, Guideline, Practice Guideline, Consensus Development Conference (and Consensus Development Conference NIH), Randomized Controlled Trial, Controlled Clinical Trial and Clinical Trial; age: adults (19 or older); language: English and Spanish; in humans, and with at least one abstract...
February 6, 2017: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/28182098/antioxidant-immunomodulating-and-microbial-modulating-activities-of-the-sustainable-and-ecofriendly-spirulina
#14
REVIEW
Alberto Finamore, Maura Palmery, Sarra Bensehaila, Ilaria Peluso
The highly nutritional and ecofriendly Spirulina (Arthrospira platensis) has hypolipidemic, hypoglycemic, and antihypertensive properties. Spirulina contains functional compounds, such as phenolics, phycocyanins, and polysaccharides, with antioxidant, anti-inflammatory, and immunostimulating effects. Studies conducted on Spirulina suggest that it is safe in healthy subjects, but attitude to eating probably affects the acceptability of Spirulina containing foods. Although the antioxidant effect of Spirulina is confirmed by the intervention studies, the concerted modulation of antioxidant and inflammatory responses, suggested by in vitro and animal studies, requires more confirmation in humans...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28181012/oral-administration-of-the-lactic-acid-bacterium-pediococcus-acidilactici-attenuates-atherosclerosis-in-mice-by-inducing-tolerogenic-dendritic-cells
#15
Taiji Mizoguchi, Kazuyuki Kasahara, Tomoya Yamashita, Naoto Sasaki, Keiko Yodoi, Takuya Matsumoto, Takuo Emoto, Tomohiro Hayashi, Naoki Kitano, Naofumi Yoshida, Hilman Zulkifli Amin, Ken-Ichi Hirata
The intestinal microbiota appears to play an important role in the development of atherosclerosis. We investigated the effect of the probiotic lactic acid bacterium Pediococcus acidilactici R037 on atherosclerosis using apolipoprotein E-deficient (ApoE (-/-)) mice. Six-week-old ApoE (-/-) mice were orally administered R037 six times a week. Mice treated with R037 for 12 weeks exhibited markedly attenuated atherosclerotic lesions in the aortic root (2.3 ± 0.15 × 10(5) µm(2) vs. 3.3 ± 0.29 × 10(5) µm(2), respectively; P < 0...
February 8, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28179092/altered-molecular-signature-of-intestinal-microbiota-in-irritable-bowel-syndrome-patients-compared-with-healthy-controls-a-systematic-review-and-meta-analysis
#16
REVIEW
Hai-Ning Liu, Hao Wu, Yu-Zhuo Chen, Yan-Jie Chen, Xi-Zhong Shen, Tao-Tao Liu
BACKGROUND: Many studies have reported significant changes in intestinal microbiota in irritable bowel syndrome (IBS) patients based on quantitative real-time PCR analysis. AIMS: We aimed to review the alterations in intestinal microbiota. METHODS: An online search up to June 9, 2016, was conducted. This systematic review and meta-analysis included differential expression of intestinal microbiota in patients with IBS versus healthy controls (HCs) and subgroup analysis...
January 21, 2017: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28178201/rett-syndrome-a-focus-on-gut-microbiota
#17
Elisa Borghi, Francesca Borgo, Marco Severgnini, Miriam Nella Savini, Maria Cristina Casiraghi, Aglaia Vignoli
Rett syndrome (RTT) is an X-linked neurodevelopmental disorder affecting 1 in 10,000 live female births. Changes in microbiota composition, as observed in other neurological disorders such as autism spectrum disorders, may account for several symptoms typically associated with RTT. We studied the relationship between disease phenotypes and microbiome by analyzing diet, gut microbiota, and short-chain fatty acid (SCFA) production. We enrolled eight RTT patients and 10 age- and sex-matched healthy women, all without dietary restrictions...
February 7, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28176664/role-of-lactic-acid-probiotic-bacteria-in-ibd
#18
Ravichandra Vemuri, Rohit Gundamaraju, Rajaraman Eri
BACKGROUND: IBD is considered as one of the major public health concerns worldwide. The pathophysiology and gut microbial alteration during inflammatory bowel disease (IBD) are still not completely understood. Gut microbiota is implicated in most of the gastro-intestinal (GI) diseases including IBD. From the time of gut microbiota establishment and through aging, it undergoes a lot of changes in the composition. METHODS: In a healthy state, the composition of beneficial microbes in the gut is comparatively higher and due to factors such as malnutrition, use of antibiotics and any underlying diseases allow the colonization and invasion of pathogens...
February 6, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28165001/microbial-shifts-in-the-porcine-distal-gut-in-response-to-diets-supplemented-with-enterococcus-faecalis-as-alternatives-to-antibiotics
#19
Pinghua Li, Qing Niu, Qingtian Wei, Yeqiu Zhang, Xiang Ma, Sung Woo Kim, Mingxin Lin, Ruihua Huang
Gut microbiota plays an important role in host health and nutrient digestion of animals. Probiotics have become one of effective alternatives to antibiotics enhancing animal health and performance through modulating gut microbiota. Previously, our research demonstrated that dietary Enterococcus Faecalis UC-100 substituting antibiotics enhanced growth and health of weaned pigs. To investigate the alterations of microbiota in the distal gut of pigs fed E. faecalis UC-100 substituting antibiotics, this study assessed fecal microbiota in pigs from different dietary treatments: the basal diet group, the E...
February 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28164854/the-microbiome-gut-brain-axis-in-health-and-disease
#20
REVIEW
Timothy G Dinan, John F Cryan
Gut microbes are capable of producing most neurotransmitters found in the human brain. Evidence is accumulating to support the view that gut microbes influence central neurochemistry and behavior. Irritable bowel syndrome is regarded as the prototypic disorder of the brain-gut-microbiota axis that can be responsive to probiotic therapy. Translational studies indicate that certain bacteria may have an impact on stress responses and cognitive functioning. Manipulating the gut microbiota with psychobiotics, prebiotics, or even antibiotics offers a novel approach to altering brain function and treating gut-brain axis disorders, such as depression and autism...
March 2017: Gastroenterology Clinics of North America
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