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https://www.readbyqxmd.com/read/28164044/accidental-bolt-gun-injury-to-femur-a-case-report
#1
Ravi Prasad Kattimani, Sanath Shetty, Humayun Mirza
INTRODUCTION: Bolt gun or slaughterer's guns are used in meat industry for "humane killing" of animals. Injuries caused by bolt gun are rare, reported exclusively from central European countries. We report a case of 28 year old male, who accidentally shot himself with a bolt gun to his right thigh. CASE REPORT: A 28 years old male presented to our Accident and Emergency department after accidental injury to his right thigh with bolt gun. He had an entry wound measuring 2 cm in length and 1 cm in breadth over anterior aspect of lower one third of thigh at lower and sustained Grade II compound fracture of right femur shaft at distal one third...
September 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28107990/combined-use-of-peptide-ion-and-normalized-delta-scores-to-evaluate-milk-authenticity-by-ion-trap-based-proteomics-coupled-with-error-tolerant-searching
#2
Donatella Nardiello, Anna Natale, Carmen Palermo, Maurizio Quinto, Diego Centonze
A fundamental issue in proteomics is the peptide identification by database searching and the assessment of the goodness of fit between experimental and theoretical data. Despite the different number of ways to measure the quality of search results, the definition of a scoring criterion is still highly desirable in ion-trap based proteomics. Indeed, in order to fully take advantage of a low resolution MS/MS dataset, it is essential to strike a balance between greater information capture and reduced number of incorrect peptide assignments...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28105494/suicide-with-two-makes-of-captive-bolt-guns-livestock-stunners-fired-simultaneously-to-the-forehead
#3
Rebecca Pircher, Dorothee Geisenberger, Markus Große Perdekamp, Merja Neukamm, Stefan Pollak, Ulrike Schmidt, Annette Thierauf-Emberger
In humans, most fatalities from slaughterer's guns are suicides committed by persons familiar with stunning devices. The great majority of cases accounts for shots to the head, especially the frontal region. Only a small number of two subsequent cranial shots from captive-bolt humane killers have been reported up to now. In the case presented by the authors, a suicide by simultaneous shots to the head fired from two different makes of captive-bolt guns (one of them having two separate outlets for the combustion gases in the muzzle plane, the other type having no additional openings) is described for the first time...
January 20, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28078445/energy-dependent-expansion-of-177-caliber-hollow-point-air-gun-projectiles
#4
Ronald Werner, Benno Schultz, Britta Bockholdt, Axel Ekkernkamp, Matthias Frank
Amongst hundreds of different projectiles for air guns available on the market, hollow-point air gun pellets are of special interest. These pellets are characterized by a tip or a hollowed-out shape in their tip which, when fired, makes the projectiles expand to an increased diameter upon entering the target medium. This results in an increase in release of energy which, in turn, has the potential to cause more serious injuries than non-hollow-point projectiles. To the best of the authors' knowledge, reliable data on the terminal ballistic features of hollow-point air gun projectiles compared to standard diabolo pellets have not yet been published in the forensic literature...
January 11, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28055070/modeling-contagion-through-social-networks-to-explain-and-predict-gunshot-violence-in-chicago-2006-to-2014
#5
Ben Green, Thibaut Horel, Andrew V Papachristos
Importance: Every day in the United States, more than 200 people are murdered or assaulted with a firearm. Little research has considered the role of interpersonal ties in the pathways through which gun violence spreads. Objective: To evaluate the extent to which the people who will become subjects of gun violence can be predicted by modeling gun violence as an epidemic that is transmitted between individuals through social interactions. Design, Setting, and Participants: This study was an epidemiological analysis of a social network of individuals who were arrested during an 8-year period in Chicago, Illinois, with connections between people who were arrested together for the same offense...
January 3, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28028921/oscillospira-and-related-bacteria-from-metagenomics-species-to-metabolic-features
#6
Uri Gophna, Tom Konikoff, Henrik Bjørn Nielsen
Oscillospira is an under-studied anaerobic bacterial genus from Clostridial cluster IV that has resisted cultivation for over a decade since the first time it was observed. In recent years its 16S rRNA gene was identified in several human gut microbiota studies where it was often associated with interesting traits, especially leanness. However, very little is known about its metabolism or physiology. Here we use nearly complete genomes derived from shot-gun metagenomic data from the human gut to analyze Oscillospira and related bacteria...
December 28, 2016: Environmental Microbiology
https://www.readbyqxmd.com/read/27964989/heavy-metals-in-the-mallard-anas-platyrhynchos-from-eastern-austria
#7
Christof Plessl, Peter Jandrisits, Regina Krachler, Bernhard K Keppler, Franz Jirsa
A total of 77 specimens of the mallard Anas platyrhynchos were sampled from the eastern part of Austria before the ban on lead gun shot for hunting water fowl. Samples of muscle and liver were analyzed for their content of Cr, Cu, Zn, Ag, Cd, Hg and Pb using atomic absorption spectrometry. In addition the Hg content of feather samples from this aquatic bird species was evaluated. Results generally show higher concentrations of the metals in the liver compared to muscle; for mercury the concentrations were feathers>liver>muscle...
December 10, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27943495/the-mitochondrial-complexome-of-arabidopsis-thaliana
#8
Jennifer Senkler, Michael Senkler, Holger Eubel, Tatjana Hildebrandt, Christian Lengwenus, Peter Schertl, Markus Schwarzländer, Stephan Wagner, Ilka Wittig, Hans-Peter Braun
Mitochondria are central to cellular metabolism and energy conversion. In plants they also enable photosynthesis through additional components and functional flexibility. A majority of those processes rely on the assembly of individual proteins to larger protein complexes, some of which operate as large molecular machines. There has been a strong interest in the makeup and function of mitochondrial protein complexes and protein-protein interactions in plants, but the experimental approaches used typically suffer from selectivity or bias...
December 10, 2016: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/27805995/rapid-thrombelastography-thresholds-for-goal-directed-resuscitation-of-patients-at-risk-for-massive-transfusion
#9
Peter M Einersen, Ernest E Moore, Michael P Chapman, Hunter B Moore, Eduardo Gonzalez, Christopher C Silliman, Anirban Banerjee, Angela Sauaia
BACKGROUND: Uncontrolled hemorrhage is a leading cause of mortality after trauma accounting for up to 40% of deaths. Massive transfusion protocols offer a proven benefit in resuscitation of these patients. Recently, the superiority of thrombelastography (TEG)-guided resuscitation over strategies guided by conventional clotting assays has been established. We seek to determine optimal thresholds for rapid (r)-TEG driven resuscitation. METHODS: The r-TEG data were reviewed for 190 patients presenting to our level 1 trauma center from 2010 to 2015...
January 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/27789243/proteomic-and-transcriptomic-investigation-of-acne-vulgaris-microcystic-and-papular-lesions-insights-in-the-understanding-of-its-pathophysiology
#10
Jusal Quanico, Jean-Pascal Gimeno, Florence Nadal-Wollbold, Christiane Casas, Sandrine Alvarez-Georges, Daniel Redoulès, Anne-Marie Schmitt, Isabelle Fournier, Michel Salzet
BACKGROUND: The pathogenesis of acne vulgaris involves several phases including androgen-dependent hyper-seborrhea, colonization by Propionibacterium acnes, and inflammation. Recent investigations have shown that in fact P. acnes provokes the activation of the inflammasome present in macrophages and dendritic cells. This signaling pathway leads to excessive production of interleukin IL-1β, a proinflammatory cytokine. Nevertheless, these well-studied phenomena in acne fail to elucidate the mechanisms responsible for the appearance of different lesions...
March 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27783497/classification-of-gunshot-residue-using-laser-electrospray-mass-spectrometry-and-offline-multivariate-statistical-analysis
#11
Johnny J Perez, David A Watson, Robert J Levis
Nonresonant laser vaporization combined with high-resolution electrospray time-of-flight mass spectrometry enables analysis of a casing after discharge of a firearm revealing organic signature molecules including methyl centralite (MC), diphenylamine (DPA), N-nitrosodiphenylamine (N-NO-DPA), 4-nitrodiphenylamine (4-NDPA), a DPA adduct, and multiple unidentified features not observed in previous mass spectral measurements. Collision-induced dissociation measurements of unknown GSR signature ions reveals inorganic barium and derivatives BaOH, BaOHCH3, BaCH3COO remaining from the primer...
December 6, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/27752640/near-complete-optic-nerve-transection-by-high-pressure-air
#12
Soo Won Ko, Jong Seok Lee, Han Sung Choi, Young Gwan Ko, Hoon Pyo Hong
The use of high-pressure air instruments has become more common. Consequently, there have been a number of cases of orbital emphysema caused by contact with high-pressure air. In this case, a 62-year-old male patient visited an emergency medical center after his left eye was shot by an air compressor gun that was used to wash cars. Lacerations were observed in the upper and lower eyelids of his left eye. Radiological examinations revealed orbital emphysema, optic nerve transection, pneumocephalus, and subcutaneous emphysema in the face, neck, shoulder, and mediastinum...
September 2016: Clinical and Experimental Emergency Medicine
https://www.readbyqxmd.com/read/27744527/bullet-fragmentation-preceding-a-contour-shot-case-study-and-experimental-simulation
#13
V Sterzik, B P Kneubuehl, M Bohnert, F Riva, M Glardon
In medico-legal literature, only a small number of publications deal with lethal injuries caused by shots with modified guns. This might lead to the conclusion that such cases are extremely rare. However, there are cases again and yet again. During the investigation process, the modified gun is of particular importance since it can show an unusual ballistic behaviour. The present paper reports on a suicide of a 60-year-old man, committed with a modified revolver and a lead bullet. The man had a single gunshot wound with entrance at the right temporal bone...
January 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/27721003/quadriparesis-caused-by-lead-poisoning-nine-years-after-a-gunshot-wound-with-retained-bullet-fragments-a-case-report
#14
Emma Nally, James Jelinek, Robert D Bunning
: Lead toxicity in adults is characterized by nonspecific symptoms of abdominal pain, vomiting, constipation, fatigue, and weight loss. We present a case of severe lead toxicity that developed subacutely, causing quadriparesis 9 years after a gunshot wound with retained bullet fragments. The onset of symptoms may have been related to the development of a pseudocyst. The long interval between the gunshot wound and the onset of symptoms contributed to a delay in suspecting that the retained bullet was a source of lead toxicity...
October 6, 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27720822/genetic-basis-for-high-population-diversity-in-protea-associated-knoxdaviesia
#15
Janneke Aylward, Emma T Steenkamp, Léanne L Dreyer, Francois Roets, Michael J Wingfield, Brenda D Wingfield
Sexual reproduction is necessary to generate genetic diversity and, in ascomycete fungi, this process is controlled by a mating type (MAT) locus with two complementary idiomorphs. Knoxdaviesia capensis and K. proteae (Sordariomycetes; Microascales; Gondwanamycetaceae) are host-specific saprophytic fungi that show high population diversity within their Protea plant hosts in the Cape Floristic Region of South Africa. We hypothesise that this diversity is the result of outcrossing driven by a heterothallic mating system and sought to describe the MAT1 loci of both species...
November 2016: Fungal Genetics and Biology: FG & B
https://www.readbyqxmd.com/read/27715652/the-effect-of-body-armor-on-saving-officers-lives-an-analysis-using-leoka-data
#16
Weiwei Liu, Bruce Taylor
Using the Law Enforcement Officers Killed and Assaulted (LEOKA; 2002-2011) database, we examined the life-saving effectiveness of body armor while adjusting for a range of confounders not assessed in previous studies. Among the 637 officers who were shot by a firearm at the torso, those who wore body armor were 76% less likely to be killed than those who did not wear armor, controlling for an array of individual and incident characteristics. A number of factors influenced officers' armor wearing behavior include age, BMI, rank, geographic region, and type of assignment...
February 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/27673104/poster-350-persistent-pneumocephalus-after-gun-shot-wound-to-the-head
#17
Kunj G Patel, Lauren E Brandes, Srikanth Kurapati, Emily Boyd, Andrew C Dennison
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27663479/using-reverse-phase-protein-arrays-as-pharmacodynamic-assays-for-functional-proteomics-biomarker-discovery-and-drug-development-in-cancer
#18
REVIEW
Yiling Lu, Shiyun Ling, Apurva M Hegde, Lauren A Byers, Kevin Coombes, Gordon B Mills, Rehan Akbani
The majority of the targeted therapeutic agents in clinical use target proteins and protein function. Although DNA and RNA analyses have been used extensively to identify novel targets and patients likely to benefit from targeted therapies, these are indirect measures of the levels and functions of most therapeutic targets. More importantly, DNA and RNA analysis is ill-suited for determining the pharmacodynamic effects of target inhibition. Assessing changes in protein levels and function is the most efficient way to evaluate the mechanisms underlying sensitivity and resistance to targeted agents...
August 2016: Seminars in Oncology
https://www.readbyqxmd.com/read/27630138/nonfatal-gun-use-in-intimate-partner-violence-a-systematic-review-of-the-literature
#19
Susan B Sorenson, Rebecca A Schut
Guns figure prominently in the homicide of women by an intimate partner. Less is known, however, about their nonfatal use against an intimate partner. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we searched eight electronic databases and identified 10 original research articles that reported the prevalence of the nonfatal use of firearms against an intimate partner. Results indicate that (1) there is relatively little research on the subject of intimate partners' nonfatal gun use against women...
September 14, 2016: Trauma, Violence & Abuse
https://www.readbyqxmd.com/read/27622112/pediatric-arm-reconstruction-after-shot-gun-injury-using-peroneal-free-flap-and-pedicled-latissimus-dorsi-muscle-flap-late-follow-up
#20
Carlos Olvera-Caballero, Abel Ortiz-Dominguez
A 15-year-old patient harmed himself upon firing a shotgun that he was carrying when he slipped and fell, causing a destructive wound in the right arm with a medial entry hole and a posterolateral exit hole. The biceps, coracobrachialis, triceps, deltoids, skin cover, and humerus were injured; however, the blood vessels and major nerves of the area were surprisingly not affected. The residual skin muscle defect after debridements was 16 × 5 cm medially and posteriorly, and the bone loss was 7 cm. The wound was reconstructed during a single surgery with a free fibula flap and a pedicled flap of latissimus dorsi...
August 2016: Plastic and Reconstructive Surgery. Global Open
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