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"Aloe vera"

Yi-Ran Wang, Guang-Xia Chen, Shi-Yan Yang, Ping Wei
Gastric cancer is the third leading cause of cancer-associated death worldwide. Although a decrease in its incidence is observed, gastric cancer still poses a major clinical challenge due to poor prognosis and limited treatments. Barbaloin (BBL) is a main medicinal composition of the Chinese traditional medicine aloe vera. BBL has various bioactivities, including anti-oxidant, anti-inflammatory and anti-tumor properties. Polydopamine (pD)-based surface modification is easy to functionalize polymeric nanoparticles (NPs) surfaces with ligands and/or additional polymeric layers...
March 10, 2018: Biochemical and Biophysical Research Communications
Sahar Dehdari, Homa Hajimehdipoor, Somayeh Esmaeili, Rasool Choopani, Seyed Alireza Mortazavi
Hemorrhoidal disease is a prevalent anorectal condition which is generally not managed well with current pharmacologic interventions. However, in Iranian traditional medicine (ITM) there are numerous plants with hemorrhoid-healing properties. The present research assembled plants with hemorrhoid-healing properties in ITM; their related pharmacological effects, phytochemical constituents and mechanisms of action in the modern medicine were also gathered. For this purpose, leading ITM textbooks were searched for plants with hemorrhoid-healing effects...
March 2018: Journal of Integrative Medicine
Shadi Alsadat Kheradvar, Jhamak Nourmohammadi, Hadi Tabesh, Behnam Bagheri
Core-sheath nanofibrous mat as a new vitamin E (VE) delivery system based on silk fibroin (SF)/poly(vinyl alcohol) (PVA)/aloe vera (AV) was successfully prepared by the electrospinning method. Initially, VE-loaded starch nanoparticles were produced and then incorporated into the best beadless SF-PVA-AV nanofibers. The successful loading of VE in starch nanoparticles was proved by Fourier-transform infrared spectroscopy. The scanning electron microscopy and transmission electron microscopy indicated that spherical nanoparticles were successfully embedded within the nanofibers...
March 2, 2018: Colloids and Surfaces. B, Biointerfaces
Dajeong Lee, Hyuk Soon Kim, Eunju Shin, Seon-Gil Do, Chong-Kil Lee, Young Mi Kim, Min Bum Lee, Keun Young Min, Jimo Koo, Su Jeong Kim, Seung Taek Nam, Hyun Woo Kim, Young Hwan Park, Wahn Soo Choi
An allergic reaction occurs when the immune system overreacts to harmless substance called allergen that gains access to the body. Food allergy is a hypersensitive immune reaction to food proteins and the number of patients with food allergy has recently increased. Aloe Vera is used for wellness and medicinal purposes. In particular, Aloe vera has been reported to enhance immunity. However, the effect of Aloe vera on food allergy is not yet known. In this study, we investigated the effects of processed Aloe vera gel (PAG) containing low molecular weight Aloe polysaccharide (AP) on ovalbumin (OVA)-induced food allergy in mice...
February 26, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
William C Gordon, Virginia García López, Surjyadipta Bhattacharjee, David Rodríguez Gil, Javier Alcover Díaz, Fernando Pineda de la Losa, Ricardo Palacios Peláez, Concha Tiana Ferrer, Gabriela Silvina Bacchini, Bokkyoo Jun, Hélène Varoqui, Nicolas G Bazan
INTRODUCTION: A major clinical challenge in treating allergic contact dermatitis (ACD) is that the first line of treatment is based on the use of corticosteroids. In this study, we aimed to develop a formulation that is devoid of steroids. METHODS: We used mouse ears treated with dinitrofluorobenzene (DNFB) to induce ACD. The efficacy of the test formulation to ameliorate and to prevent induced ACD was determined. RESULTS: To treat this experimentally induced ACD, we developed a formulation containing BIPxine (a mixture of Rosa moschata and Croton lechleri (antioxidants) and Aloe vera and D-panthenol (moisturizers), and hydroglycolic solutions of disodium cromoglycate...
February 16, 2018: Dermatology and Therapy
Zhongchuang Liu, Li-Ao Wang, Shimin Ding, Yuehan Li
The paper discussed the effects of growth agents and mercury on the growth of four herb species subjected to a pot experiment: Aloe vera, Setcreasea purpurea, Chlorophytum comosum, and Oxalis corniculata. We determined the height and biomass production of selected plants treated with different growth agents and different concentrations of mercury solutions. We evaluated the relative growth rate (RGR) of the experimental plants. The aim of the study was to explore potential novel solutions to the shortcoming of the low speed of phytoremediation...
February 15, 2018: Environmental Science and Pollution Research International
Ahmed Ibrahim El-Batal, Salwa Farid Ahmed
Radiation combined injury, a life-threatening condition, has higher mortality than simple radiation injury. The aim of the present study was to analyze the efficiency of Aloe vera and silver nanoparticles in improving the healing of ulcerated oral mucosa after irradiation. Thirty male Albino mice were divided into five groups: control, radiation, Aloe vera (AV), silver nanoparticles (NS), and AV+NS. The mice were exposed to whole body 6Gy gamma-radiation. After one hour, 20% acetic acid was injected into the submucosal layer of the lower lip for ulcer induction...
February 5, 2018: Brazilian Oral Research
Adriana Y Koga, Airton V Pereira, Leandro C Lipinski, Marcia Rp Oliveira
A new alginate dressing with Aloe vera gel was developed and used to study its cutaneous healing effect in vivo by surgical wounds in Wistar rats. The aloe-alginate film was characterized by Fourier-transform infrared spectroscopy, mechanical properties, scanning electron microscopy, hydration rate, and calcium release. The aloe-alginate film demonstrated desirable physical and mechanical characteristics for wound dressing application. The animals were divided in three groups (n = 20): gauze bandage, alginate film, and aloe-alginate film...
January 1, 2018: Journal of Biomaterials Applications
Reza Ranjbar, Alireza Yousefi
Objective: To assess effect of Aleo vera with chitosan nanoparticle biofilm on wound healing in full thickness infected wounds with antibiotic resistant gram positive bacteria. Method: Thirty rats were randomized into five groups of six rats each. Group I: Animals with uninfected wounds treated with 0.9% saline solution. Group II: Animals with infected wounds treated with saline. Group III: Animals with infected wounds were dressed with chitosan nanoparticle thin-film membranes...
January 2018: Bulletin of Emergency and Trauma
Magda I Pinzon, Omar R Garcia, Cristian C Villa
BACKGROUND: Aloe vera (AV) gel is a promising material in food conservation, given its widely reported antimicrobial and antioxidant activity; however, its application in the formation of edible films and coatings has been small due its low film forming capability. The aim of this study was to investigate the physicochemical properties of film forming solutions and films prepared using unriped banana starch-chitosan and AV Gel at different AV Gel concentration. RESULTS: Our results showed that AV gel considerably affects the rheological and optical properties of the edible coatings, mainly due to increased amounts of solids brought by the AV gel...
January 27, 2018: Journal of the Science of Food and Agriculture
Geir Bjørklund, Maryam Dadar, Natália Martins, Salvatore Chirumbolo, Bey Hing Goh, Kateryna Smetanina, Roman Lysiuk
Several studies have reported that nature-derived antioxidants may prevent free radicals over-production and therefore control the onset and prevent the exacerbation of different kinds of diseases caused by oxidative stress and redox-derived stressors, including ageing, fundamentally by suppressing the oxidative byproducts-mediated degradation. Naturally derived antioxidants exert their anti-ageing action via a panoply of signalling systems, many of which engaging reactive oxygen (ROS) and nitrogen (RNS) species scavenging, with the Nrf2/Keap1-ARE system and improving the many survival genes and functions (such as the pathway mTOR/Foxo/SIRT1) able to slow cellular senescence...
January 25, 2018: Basic & Clinical Pharmacology & Toxicology
Nabil A Ibrahim, Nahed A Abd El-Ghany, Basma M Eid, Eman M Mabrouk
This study demonstrated that antibacterial cellulosic textiles can be fabricated in eco-friendly manner by grafting of monochlorotriazinyl β-cyclodextin (MCT-βCD) onto knitted and woven cotton fabrics followed by post-loading of any of the green active ingredients namely Rosemary oil, Lavender oil, Clove oil, Cinnamon oil, Aloe vera gel, Vanillin, Ag-ions, Natural Yellow 7 and Natural Red 25 dyes into the hydrophobic cavities of grafted β-CD moieties. Some of the grafted, post-loaded fabric samples were characterized by FTIR, SEM, and EDS analysis...
January 11, 2018: International Journal of Biological Macromolecules
Younes Najafian, Zahra Mazloum, Mona Najaf Najafi, Shokouhsadat Hamedi, Marjan Mahjour, Zohre Feyzabadi
BACKGROUND: Diabetic foot ulcer (DFU) is one of the most common complications of diabetic patients. Mostly, non-healing DFU leads to infection, gangrene, amputation and even death. High costs and poor healing of the wounds need a new treatment such as alternative medicine. So, the aim of this study was to evaluate the efficacy of Aloe vera/ Plantago major gel (Plantavera gel) in healing of DFU. METHODS: Forty patients with DFU enrolled in a double-blind randomized clinical trial...
January 14, 2018: Current Drug Discovery Technologies
Sachin G Khatri, Srinivasan Raj Samuel, Shashidhar Acharya, Snehal T Patil
PURPOSE: Various candida species have been associated with poor oral hygiene and active carious lesions. The purpose of this study was to evaluate the effectiveness of aloe vera compared to triclosan toothpaste against total candida, C. albicans, C. tropicalis, Candida krusei, and plaque/gingivitis among intellectually disabled adolescents over 30 days. METHODS: A double-blind prospective randomized trial was conducted among 40 intellectually disabled adolescents randomly allocated into aloe vera/triclosan groups...
November 1, 2017: Pediatric Dentistry
Ayesha Noor, S Gunasekaran, M A Vijayalakshmi
Background: Diabetes mellitus is a metabolic disorder characterized by chronic hyperglycemia. Plant extracts and their products are being used as an alternative system of medicine for the treatment of diabetes. Aloe vera has been traditionally used to treat several diseases and it exhibits antioxidant, anti-inflammatory, and wound-healing effects. Streptozotocin (STZ)-induced Wistar diabetic rats were used in this study to understand the potential protective effect of A. vera extract on the pancreatic islets...
December 2017: Pharmacognosy Research
Flavia Laffleur
This present study intended to provide nasal adhesive formulations for the topical treatment of dry nasal syndrome. Mucoadhesive films were prepared according to solvent evaporation method consisting of well-known polymers such as gellan and carboxymethyl cellulose. Mucoadhesive films (A-E) were evaluated in respect to their physicochemical properties, stability, disintegration behavior and tensile strength. Moreover, uptake capacity of adhesive films was investigated according to three assays vapor uptake/ permeability and water uptake...
January 9, 2018: International Journal of Biological Macromolecules
Utari Kresnoadi, Retno Pudji Rahayu, M Rubianto, Subijanto Marto Sudarmo, Hendrik Setia Budi
The aim of this study was to find the role of TLR2 signaling pathway in reducing osteoclast activity and promoting osteoblast growth by inducing a combination of Aloe vera and cancellous bovine xenograft (XCB) into dental extraction socket. Forty-eight Cavia cobayas were used. They were divided into eight groups (n=6). For control group, their mandibular incisors were extracted and filled with PEG. For treatment groups, they were extracted and filled with XCB, Aloe vera and the combination of Aloe vera and XCB...
May 2017: Brazilian Dental Journal
Herin Mawarti, Mukhamad Rajin, Zulfikar Asumta
Background: The present study was undertaken to investigate the hepatoprotective effect of Aloe vera against side effect of antituberculosis drug. Material and methods: Twenty-five rats will be divided into five groups, namely the control group (without any treatment), the group of rats treated with anti-tuberculosis drugs, and a group of rats were treated antituberculosis drugs and got Aloe vera extract at a dose of 40; 80; and 120 mg/kg body weight. Antituberculosis drugs are isoniazid and rifampicin a dose of 50 mg/kg body weight...
October 2017: Medical Archives
Tao Chen, Li Wang, Chunyan Hu
Aloe vera is a widely used natural herb from which many sorts of commercial products have been derived using different preparation technologies. Aloe whole-leaf powder is one of the most popular subtypes. The long-term impact of aloe products has already been reported; however, there have been few studies about short-term exposure, and especially about the relative impact of Aloe vera whole-leaf freeze-dried powder (AWFP). To provide more toxicological data and to document the early changes induced by AWFP, in this study 120 SD rats were divided into four groups (control and 400/1200/2000 mg/kg treatment groups) and were administered AWFP once daily by oral gavage for 28 consecutive days, followed by a two week recovery phase...
October 2017: International Journal of Experimental Pathology
Wei-Song Kong, Jing Li, Xin Liu, Qi-Li Mi, Jian-Hua Chen, Xue-Mei Li, Guang-Yu Yang, Qiu-Fen Hu, Tao Li, Ye-Kun Yang
A new naphthalene derivative has been isolated from Aloe vera by using various chromatographic techniques, including silica gel, sephadex, MCI-gel resin, and RP-HPLC. The new compound was determined as 3-hydroxy-1-(1,7-dihydroxy-3,6-dimethoxynaphthalen-2-yl)propan-1-one (1). In the biological activity assay, compound 1 disglayed prominent antibacterial activity with a MIC90 value of (48±4) mg•L⁻¹ for methicillin resistant Staphylococcus aureus (MRSA) strain which was stronger than that of the positive control levofloxacin with a MIC90 value (58±5) mg•L⁻¹...
October 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
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