keyword
MENU ▼
Read by QxMD icon Read
search

"Red yeast"

keyword
https://www.readbyqxmd.com/read/29739570/high-throughput-screening-and-profiling-of-high-value-carotenoids-from-a-wide-diversity-of-bacteria-in-surface-seawater
#1
Dalal Asker
Carotenoids are valuable natural colorants that exhibit numerous health promoting properties, and thus are widely used in food, feeds, pharmaceutical and nutraceuticals industries. In this study, we isolated and identified novel microbial sources that produced high-value carotenoids using high throughput screening (HTS). A total of 701 pigmented microbial strains library including marine bacteria and red yeast was constructed. Carotenoids profiling using HPLC-DAD-MS methods showed 88 marine bacterial strains with potential for the production of high-value carotenoids including astaxanthin (28 strains), zeaxanthin (21 strains), lutein (1 strains) and canthaxanthin (2 strains)...
September 30, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29609929/red-yeast-rice-ryr-supplementation-in-patients-treated-with-second-generation-antipsychotics
#2
Antonio Bruno, Gianluca Pandolfo, Manuela Crucitti, Giulia Maria Troili, Edoardo Spina, Rocco Antonio Zoccali, Maria Rosaria Anna Muscatello
OBJECTIVE: Second-generation antipsychotics (SGAs) have a negative impact on metabolic syndrome (MetS) risk factors for their effects on body weight and on metabolic parameters. Statins are widely used in the treatment of dyslipidemia; less is known on the ability of statins to treat SGAs-induced dyslipidemia, and nutraceutical approaches may represent promising strategies in SGAs-treated patients. Red Yeast Rice (RYR), the fermented product of the Aspergillaceae mold Monascus purpureus (red yeast) grown on white rice, has been shown to have a cholesterol-lowering effect which can be ascribed to monacolin K, although other active compounds may play a role management of hyperlipidemia...
April 2018: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/29600651/-trace-phenolic-compounds-from-red-yeast-rice
#3
Yu-Bin Ji, Fei Xu, Bing-Yu Liu, Qian Wei, Yong-Zhi Guo, Yu Dong, Ying Sun, You-Cai Hu
Trace chemical constituents from the ethyl acetate extract of Red Yeast Rice were investigated. Four phenolic compounds were isolated by various column chromatographies, and their structures were identified on the basis of spectroscopic analysis including UV, MS, IR and NMR. The four compounds were identified as 2-methyl-5-(2'R-methyl-4'-hydroxy-butyl)-cinnamic acid(1), 5-(2'-hydroxy-6'-methyl phenyl)-3-methylfuran-2-carboxylic acid(2), daidzein(3), and genistein(4). Compound 1 was new and 2 was firstly discovered from the genus Monascus, while 3-4 were obtained from Red Yeast Rice for the first time...
February 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29582393/adverse-events-to-food-supplements-containing-red-yeast-rice-comparative-analysis-of-faers-and-caers-reporting-systems
#4
Emanuel Raschi, Anna Girardi, Elisabetta Poluzzi, Emanuele Forcesi, Francesca Menniti-Ippolito, Gabriela Mazzanti, Fabrizio De Ponti
INTRODUCTION: Food supplements containing red yeast rice (RYR) are proposed as an alternative in statin-intolerant patients, although they actually contain natural statin(s) and their safety in clinical practice is still incompletely characterized. We described and compared adverse events (AEs) associated with RYR products submitted to reporting systems maintained by the Food and Drug Administration (FDA), with a focus on liver and muscular events. METHODS: We extracted RYR-related AEs from the FDA Adverse Event Reporting System (FAERS) [first quarter (Q1)-2004 to Q2-2016], a drug-based archive, and the Center for Food Safety and Applied Nutrition Adverse Event Reporting System (CAERS) (Q1-2004 to Q1-2017)...
March 26, 2018: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/29552653/engineering-of-yarrowia-lipolytica-for-production-of-astaxanthin
#5
Kanchana Rueksomtawin Kildegaard, Belén Adiego-Pérez, David Doménech Belda, Jaspreet Kaur Khangura, Carina Holkenbrink, Irina Borodina
Astaxanthin is a red-colored carotenoid, used as food and feed additive. Astaxanthin is mainly produced by chemical synthesis, however, the process is expensive and synthetic astaxanthin is not approved for human consumption. In this study, we engineered the oleaginous yeast Yarrowia lipolytica for de novo production of astaxanthin by fermentation. First, we screened 12 different Y. lipolytica isolates for β-carotene production by introducing two genes for β-carotene biosynthesis: bi-functional phytoene synthase/lycopene cyclase ( crtYB ) and phytoene desaturase ( crtI ) from the red yeast Xanthophyllomyces dendrorhous ...
December 2017: Synthetic and Systems Biotechnology
https://www.readbyqxmd.com/read/29531380/-nutraceuticals-a-useful-tool-for-cardiologists-to-improve-lipid-profile
#6
Elisa Covolo, Claudio Bilato
Hyperlipidemia is a major risk factor for cardiovascular morbidity and mortality. Treatment strategies include both lifestyle modification and pharmacological therapy. Statins are among the most effective agents to achieve optimal LDL-cholesterol levels, but, not infrequently, patients suffer from myalgia or other side effects. The proven or perceived intolerance to statins requires, therefore, alternative lipid-lowering strategies. In recent years, nutraceuticals have become extensively accepted, and a growing number of molecules with hypothetical cholesterol-lowering activity have been proposed, sometimes with no scientific evidence and/or no methodological accuracy, based only on the belief that these agents are "natural" and do not show side effects...
February 2018: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/29509070/direct-bioconversion-of-rice-residue-from-canteen-waste-into-lipids-by-new-amylolytic-oleaginous-yeast-sporidiobolus-pararoseus-kx709872
#7
Thanongsak Chaiyaso, Wimada Srisuwan, Charin Techapun, Masanori Watanabe, Shinji Takenaka
The new amylolytic oleaginous red yeast, Sporidiobolus pararoseus KX709872, produced both α-amylase (540 ± 0.09 mU/mL) and amyloglucosidase (23 ± 0.00 mU/mL) and showed good ability to directly convert rice residue from canteen waste to biomass and lipids. Effects of medium composition and cultivation conditions on growth and lipid accumulation for strain KX709872 were investigated under shaking flask and upscaling levels. At C : N ratio of 25 : 1, pH 5.45, 22.36°C, and 199.40 rpm for 7 days, volumetric production of biomass and lipids, lipid content, and lipid productivity reached 17...
April 21, 2018: Preparative Biochemistry & Biotechnology
https://www.readbyqxmd.com/read/29493648/-red-yeast-rice-monacolin-k-and-pleiotropic-effects
#8
Arrigo Francesco Giuseppe Cicero
The extracts of red yeast rice represent a nutraceutical with proven cholesterol lowering effect. Its efficacy is proportional to the concentration on monacolin K in the extract that could reach the amount of 10 mg per daily dose. The daily assumption of monacolin K could then reduce LDL-cholesterol plasma levels by 15-25% in 6-8 weeks. The LDL-cholesterol reduction is associated with a proportional reduction in total cholesterolemia, non-HDL cholesterolemia, plasma apolipoprotein B, high-sensitivity C-reactive protein, and matrix metalloproteinases 2 and 9...
February 2018: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/29414159/enhanced-single-cell-oil-production-by-mixed-culture-of-chlorella-pyrenoidosa-and-rhodotorula-glutinis-using-cassava-bagasse-hydrolysate-as-carbon-source
#9
Lu Liu, Junhui Chen, Phaik-Eem Lim, Dong Wei
The single cell oil (SCO) production by the mono and mixed culture of microalgae Chlorella pyrenoidosa and red yeast Rhodotorula glutinis was investigated using non-detoxified cassava bagasse hydrolysate (CBH) as carbon source. The results suggested that the two strains were able to tolerate and even degrade some byproducts presented in the CBH, and the mixed culture approach enhanced the degradation of certain byproducts. Biomass (20.37 ± 0.38 g/L) and lipid yield (10.42 ± 1.21 g/L) of the mixed culture achieved in the batch culture were significantly higher than that of the mono-cultures (p < 0...
May 2018: Bioresource Technology
https://www.readbyqxmd.com/read/29371528/combinatorial-biosynthesis-of-novel-multi-hydroxy-carotenoids-in-the-red-yeast-xanthophyllomyces-dendrorhous
#10
Hendrik Pollmann, Jürgen Breitenbach, Hendrik Wolff, Helge B Bode, Gerhard Sandmann
The red yeast Xanthophyllomyces dendrorhous is an established platform for the synthesis of carotenoids. It was used for the generation of novel multi oxygenated carotenoid structures. This was achieved by a combinatorial approach starting with the selection of a β-carotene accumulating mutant, stepwise pathway engineering by integration of three microbial genes into the genome and finally the chemical reduction of the resulting 4,4'-diketo-nostoxanthin (2,3,2',3'-tetrahydroxy-4,4'-diketo-β-carotene) and 4-keto-nostoxanthin (2,3,2',3'-tetrahydroxy-4-monoketo-β-carotene)...
February 22, 2017: Journal of Fungi (Basel, Switzerland)
https://www.readbyqxmd.com/read/29365452/efficacy-and-safety-of-a-nutraceutical-with-probiotic-and-red-yeast-rice-extract-in-patients-with-moderate-hypercholesterolemia-a-randomized-double-blind-placebo-controlled-study
#11
Chiara Macchi, Margherita Botta, Raffaella Bosisio, Chiara Pavanello, Chiara Maria Toldo, Giuliana Mombelli, Laura Calabresi, Massimiliano Ruscica, Paolo Magni
No abstract text is available yet for this article.
August 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29350661/retrospective-analysis-of-the-effects-of-a-highly-standardized-mixture-of-berberis-aristata-silybum-marianum-and-monacolins-k-and-ka-in-diabetic-patients-with-dyslipidemia
#12
Francesco Di Pierro, Pietro Putignano, Nicola Villanova
BACKGROUND: Berberine, an alkaloid with both glucose- and cholesterol-lowering action, is also characterized by an anti-diarrheal effect. Consequently, berberine-based therapies are recommended for diabetic patients with irritable bowel syndrome (IBS) or gut discomfort caused by metformin. AIM: As the anti-glycemic and cholesterol-lowering action of berberine is improved by co-administration with P-glycoprotein inhibitors and naturally derived statins, we have analyzed the effect of the food supplement Berberol®K (hereafter referred to as BSM) containing, berberine, silymarin, and a highly standardized red yeast rice containing monacolins K and KA in the ratio 1:1 but no secondary monacolins, dehydromonacolins, or citrinin (Monakopure™-K20)...
January 16, 2018: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29290214/dietary-management-of-dyslipidaemias-is-there-any-evidence-for-cardiovascular-benefit
#13
REVIEW
Panagiotis Anagnostis, Stavroula A Paschou, Dimitrios G Goulis, Vasilios G Athyros, Asterios Karagiannis
Specific dietary strategies are the mainstay of management in most cases of dyslipidaemia, prior to or simultaneously with the initiation of a lipid-lowering agent. The exact approach differs according to the type of dyslipidaemia. In particular, a reduction in carbohydrates (mainly foods with a high glycaemic index) and their substitution with mono- and polyunsaturated fatty acids is the main strategy in patients with high levels of triglycerides (Tg) and/or low levels of high-density lipoprotein cholesterol (HDL-c)...
February 2018: Maturitas
https://www.readbyqxmd.com/read/29239815/provider-recommendations-for-patient-reported-muscle-symptoms-on-statin-therapy-insights-from-the-understanding-statin-use-in-america-and-gaps-in-patient-education-survey
#14
Terry A Jacobson, Abdullah Khan, Kevin C Maki, Eliot A Brinton, Jerome D Cohen
BACKGROUND: Statin-associated muscle symptoms are reported by 10% to 29% of patients in clinical practice and are a major determinant of statin nonadherence, discontinuation, and switching. Little is known about what advice patients receive from their providers when dealing with these symptoms. OBJECTIVE: The objective of the study was to assess patient's reports of provider advice when experiencing new or worsened muscle symptoms while taking a statin. METHODS: Data were analyzed from the Understanding Statin Use in America and Gaps in Education survey, a self-administered internet-based survey of 10,138 adults with a reported history of high cholesterol and statin use...
January 2018: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/29190732/xuezhikang-an-extract-from-red-yeast-rice-attenuates-vulnerable-plaque-progression-by-suppressing-endoplasmic-reticulum-stress-mediated-apoptosis-and-inflammation
#15
Linghong Shen, Zhe Sun, Shichun Chu, Zhaohua Cai, Peng Nie, Caizhe Wu, Ruosen Yuan, Liuhua Hu, Ben He
Xuezhikang (XZK), an extract of red yeast rice, is a traditional Chinese medicine widely used for the treatment of cardiovascular diseases in China and other countries. However, whether XZK treatment can improve atherosclerotic plaque stability is not fully understood. Based on our previously developed mouse model of spontaneous vulnerable plaque formation and rupture in carotid arteries in ApoE-/- mice. We showed that low-dose (600 mg/kg/d) XZK improved plaque stability without decreasing plaque area, whereas high-dose (1200 mg/kg/d) XZK dramatically inhibited vulnerable plaque progression accompanied by decreased plaque area...
2017: PloS One
https://www.readbyqxmd.com/read/29154060/efficacy-and-safety-of-a-combination-of-red-yeast-rice-and-olive-extract-in-hypercholesterolemic-patients-with-and-without-statin-associated-myalgia
#16
Christian Tshongo Muhindo, Sylvie A Ahn, Michel F Rousseau, Yvan Dierckxsens, Michel P Hermans
Cholesfytol®, a lipid-lowering dietary supplement with antioxidant and anti-atherosclerotic properties, combines red yeast rice (RYR) and olive extract (5mg hydroxytyrosol equivalent) and represents an alternative for patients who do not wish or are unable to use chemical statins, including individuals with previous statin-associated muscle symptoms (SAMS). A 2-months observational non-randomized study was performed to evaluate the efficacy, tolerance and safety of Cholesfytol® (1 tablet/day) in 642 hypercholesterolemic patients (mean age: 59 yrs; total cholesterol (TC) ≥200; LDL-C ≥140mg/dl)...
December 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/29035150/enhancement-of-carotenoids-and-lipids-production-by-oleaginous-red-yeast-sporidiobolus-pararoseus-km281507
#17
Thanongsak Chaiyaso, Atchara Manowattana
Bioconversion of biodiesel-derived crude glycerol into carotenoids and lipids was investigated by a microbial conversion of an oleaginous red yeast Sporidiobolus pararoseus KM281507. The methanol content in crude glycerol (0.5%, w/v) did not show a significant effect on biomass production by strain KM281507. However, demethanolized crude glycerol significantly supported the production of biomass (8.64 ± 0.13 g/L), lipids (2.92 ± 0.03 g/L), β-carotene (15.76 ± 0.85 mg/L), and total carotenoids (33...
January 2, 2018: Preparative Biochemistry & Biotechnology
https://www.readbyqxmd.com/read/29021813/effect-of-a-short-term-dietary-supplementation-with-phytosterols-red-yeast-rice-or-both-on-lipid-pattern-in-moderately-hypercholesterolemic-subjects-a-three-arm-double-blind-randomized-clinical-trial
#18
Arrigo F G Cicero, Federica Fogacci, Martina Rosticci, Angelo Parini, Marina Giovannini, Maddalena Veronesi, Sergio D'Addato, Claudio Borghi
BACKGROUND: Phytosterols and red yeast rice are largely studied cholesterol-lowering nutraceuticals, respectively inhibiting the bowel absorption and liver synthesis of cholesterol. Our aim was to test the effect on lipid profile of phytosterols, red yeast rice and their association. METHODS: We performed a three parallel arms, double blind, clinical trial randomizing 90 moderately hypercholesterolemic subjects to treatment with phytosterols 800 mg (group 1), red yeast rice standardized to contain 5 mg monacolins from Monascus purpureus (group 2), or both combined nutraceuticals (group 3)...
2017: Nutrition & Metabolism
https://www.readbyqxmd.com/read/28944737/alginate-gelatin-formulation-to-modify-lovastatin-release-profile-from-red-yeast-rice-for-hypercholesterolemia-therapy
#19
Gemma Leone, Marco Consumi, Simone Pepi, Stefania Lamponi, Claudia Bonechi, Gabriella Tamasi, Alessandro Donati, Claudio Rossi, Agnese Magnani
AIM: The preparation of a delivery system able to guarantee a delayed release of lovastatin from red yeast rice (RYR) is mandatory to counteract cholesterol biosynthesis effectively. MATERIALS & METHODS: Polymeric formulations were prepared mixing alginate and gelatin, in different ratios, with RYR. The effect of different composition on stiffness, viscosity, swelling behavior and mesostructure of matrices was analyzed. RESULTS: Formulations obtained combining polymers in comparable amount (i...
October 2017: Therapeutic Delivery
https://www.readbyqxmd.com/read/28934253/xuezhikang-contributes-to-greater-triglyceride-reduction-than-simvastatin-in-hypertriglyceridemia-rats-by-up-regulating-apolipoprotein-a5-via-the-ppar%C3%AE-signaling-pathway
#20
Shui-Ping Zhao, Rong Li, Wen Dai, Bi-Lian Yu, Lu-Zhu Chen, Xian-Sheng Huang
Xuezhikang (XZK), an extract of Chinese red yeast rice, is recommended as an optimal choice for patients with coronary heart disease (CHD) with markedly elevated triglyceride (TG) levels. This study was designed to compare the hypotriglyceridemic effects between XZK and simvastatin. The role of apolipoprotein A5 (apoA5), a key regulator of TG metabolism and a target gene of peroxisome proliferator-activated receptor α (PPARα), was to be identified in XZK-related hypotriglyceridemic actions. For these goals, hypertriglyceridemia of rats was induced by a high-fructose diet...
2017: PloS One
keyword
keyword
115819
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"