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https://www.readbyqxmd.com/read/28545114/different-adaptation-strategies-of-two-citrus-scion-rootstock-combinations-in-response-to-drought-stress
#1
Joadson Dutra de Souza, Edson Mario de Andrade Silva, Mauricio Antônio Coelho Filho, Raphaël Morillon, Diego Bonatto, Fabienne Micheli, Abelmon da Silva Gesteira
Scion/rootstock interaction is important for plant development and for breeding programs. In this context, polyploid rootstocks presented several advantages, mainly in relation to biotic and abiotic stresses. Here we analyzed the response to drought of two different scion/rootstock combinations presenting different polyploidy: the diploid (2x) and autotetraploid (4x) Rangpur lime (Citrus limonia, Osbeck) rootstocks grafted with 2x Valencia Delta sweet orange (Citrus sinensis) scions, named V/2xRL and V/4xRL, respectively...
2017: PloS One
https://www.readbyqxmd.com/read/28544964/biophysical-and-biological-studies-of-some-polymer-grafted-metallo-intercalators
#2
Yesaiyan Manojkumar, Subramanian Ambika, Rajendran Senthilkumar, Sankaralingam Arunachalam
Two water-soluble polymer-copper(II) complexes, [Cu(ip)2(BPEI)](ClO4)2·H2O (Complex 1) and [Cu(dppz)2BPEI](ClO4)2·H2O (Complex 2) with different degree of coordination have been synthesized and characterized. The interaction between the prepared complexes and CTDNA has been assessed by various physico-chemical methods The spectroscopic and the cyclic voltammetry studies have revealed that both the complexes interact with CTDNA through intercalation binding mode. Among the two complexes, Complex 2 has higher binding affinity with CTDNA...
May 15, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28544959/effect-of-different-mineralization-processes-on-in-vitro-and-in-vivo-bone-regeneration-and-osteoblast-macrophage-cross-talk-in-co-culture-system-using-dual-growth-factor-mediated-non-mulberry-silk-fibroin-grafted-poly-%C3%B0-caprolactone-nanofibrous-scaffold
#3
Promita Bhattacharjee, Tapas K Maiti, Debasis Bhattacharya, Samit Kumar Nandi
This study evaluates mineralized nanofibrous polymeric scaffolds at supporting in vitro osteogenic differentiation of human mesenchymal stem cells (hMSCs) and in vivo bone tissue regeneration. Co-electrospin, alternative soaking, and electrodeposition were used to introduce hydroxyapatite in non-mulberry silk fibroin grafted poly(Є-caprolactone) nanofibrous scaffolds. Bone morphogenic protein-2 and Transforming growth factor-β, at a potency ratio of 1:1, are covalently coupled onto the scaffolds. hMSCs proliferation and interactions are studied through MTT and Alamar blue assay and scanning electron and confocal microscopy...
May 16, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28544831/aortic-root-surgery-in-marfan-syndrome-medium-term-outcome-in-a-single-center-experience
#4
Christine H Attenhofer Jost, Heidi M Connolly, Christopher G Scott, Naser M Ammash, Juan M Bowen, Hartzell V Schaff
BACKGROUND: The study aim was to analyze the authors' experience with aortic root surgery in Marfan syndrome (MFS), and to expand the surgical outcome data of patients meeting the Ghent criteria (Marfan registry). METHODS: Analyses were performed of data acquired from MFS patients (who met the Ghent criteria), including an aortic root surgery and Kaplan-Meier survival. RESULTS: Between April 2004 and February 2012, a total of 59 MFS patients (mean age at surgery 36 ± 13 years) underwent 67 operations for aortic root aneurysm (n = 52), aortic valve (AV) regurgitation (n = 15), acute aortic dissection (n = 2), and/or mitral valve (MV) regurgitation resulting from MV prolapse (n = 7)...
January 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28544815/fabrication-of-viable-and-functional-pre-vascularized-modular-bone-tissues-by-coculturing-mscs-and-huvecs-on-microcarriers-in-spinner-flasks
#5
Songjie Zhang, Min Zhou, Zhaoyang Ye, Yan Zhou, Wen-Song Tan
BACKGROUND AND AIM: Slow vascularization often impedes the viability and function of engineered bone replacements. Prevascularization is a promising way to solve this problem. In this study, a new process was developed by integrating microcarrier culture and coculture to fabricate pre-vascularized bone microtissues with mesenchymal stem cells (MSCs) and human umbilical vein endotheli-al cells (HUVECs). METHODOLOGY: Initially, coculture medium and cell ratio between MSCs and HUVECs were optimized in tissue culture plates concerning cell proliferation, osteogenesis and angiogenesis...
May 24, 2017: Biotechnology Journal
https://www.readbyqxmd.com/read/28544743/deconvoluting-the-bioactivity-of-calcium-phosphate-based-bone-graft-substitutes-strategies-to-understand-the-role-of-individual-material-properties
#6
REVIEW
Víctor Pablo Galván-Chacón, Pamela Habibovic
Calcium phosphate (CaP)-based ceramics are the most widely applied synthetic biomaterials for repair and regeneration of damaged and diseased bone. CaP bioactivity is regulated by a set of largely intertwined physico-chemical and structural properties, such as the surface microstructure, surface energy, porosity, chemical composition, crystallinity and stiffness. Unravelling the role of each individual property in the interaction between the biomaterial and the biological system is a prerequisite for evolving from a trial-and-error approach to a design-driven approach in the development of new functional biomaterials...
May 23, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28544662/tracheal-replacement-therapy-with-a-stem-cell-seeded-graft-lessons-from-compassionate-use-application-of-a-gmp-compliant-tissue-engineered-medicine
#7
Martin J Elliott, Colin R Butler, Aikaterini Varanou-Jenkins, Leanne Partington, Carla Carvalho, Edward Samuel, Claire Crowley, Peggy Lange, Nicholas J Hamilton, Robert E Hynds, Tahera Ansari, Paul Sibbons, Anja Fierens, Claire McLaren, Derek Roebuck, Colin Wallis, Nagarajan Muthialu, Richard Hewitt, David Crabbe, Sam M Janes, Paolo De Coppi, Mark W Lowdell, Martin A Birchall
Tracheal replacement for the treatment of end-stage airway disease remains an elusive goal. The use of tissue-engineered tracheae in compassionate use cases suggests that such an approach is a viable option. Here, a stem cell-seeded, decellularized tissue-engineered tracheal graft was used on a compassionate basis for a girl with critical tracheal stenosis after conventional reconstructive techniques failed. The graft represents the first cell-seeded tracheal graft manufactured to full good manufacturing practice (GMP) standards...
June 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28544635/a-robust-water-based-functional-binder-framework-for-high-energy-lithium-sulfur-batteries
#8
Matthew James Lacey, Viking Österlund, Fabian Jeschull, Andreas Bergfelt, Tim Bowden, Daniel Brandell
We report here a water-based functional binder framework for the lithium-sulfur battery system, based on the general combination of a polyether and an amide-containing polymer. These binders are applied here to positive electrodes optimised towards high energy electrochemical performance based only on commercially available materials. Electrodes with up to 4 mAh cm-2 capacity and 97 - 98% coulombic efficiency are achievable in electrodes with a 65% total sulfur content and a poly(ethylene oxide):poly(vinylpyrrolidone) (PEO:PVP) binder system...
May 19, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28544623/amphoteric-ion-exchange-membranes-with-significantly-improved-vanadium-barrier-properties-for-all-vanadium-redox-flow-batteries
#9
Olga Nibel, Tomasz Rojek, Thomas J Schmidt, Lorenz Gubler
All-vanadium redox flow batteries (VRBs) have attracted considerable interest as promising energy storage devices which can allow the efficient utilization of renewable energy sources. The membrane, which separates the porous electrodes in a redox flow cell, is one of the key components in VRBs. High rates of cross-over of vanadium ions and water through the membrane impair the efficiency and capacity of a VRB. Thus, membranes with low permeation rate of vanadium species and water are required, also characterized by low resistance and stability in the VRB environment...
May 23, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28544600/effect-of-magnesium-on-arrhythmia-incidence-in-patients-undergoing-coronary-artery-bypass-grafting
#10
Alireza Mohammadzadeh, Farshad Towfighi, Naser Jafari
BACKGROUND: Cardiac arrhythmia after coronary artery bypass grafting (CABG) surgery is a common complication of cardiac surgery. The effect of serum magnesium, hypomagnesaemia treatment and prophylactic administration of magnesium in the development and prevention of arrhythmias is controversial and there are many different ideas. This study evaluates the therapeutic effects of magnesium in cardiac arrhythmia after CABG surgery. METHODS: The clinical trial enrolled 250 patients who underwent CABG...
May 22, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28544515/survival-rates-after-liver-transplantation-using-hypertensive-donor-grafts-an-analysis-of-the-scientific-registry-of-transplant-recipients-database
#11
Zhenhua Hu, Shengmin Mei, Jie Xiang, Jie Zhou, Zhiwei Li, Lin Zhou, Sheng Yan, Weilin Wang, Shusen Zheng
BACKGROUND: The use of grafts from hypertension (HTN) donors in liver transplantation (LT) has grown rapidly in recently, but whether HTN donor affects post-LT survival is unclear. METHOD: We used data from the Scientific Registry of Transplant Recipients database (2004-2008) and evaluated differences in baseline characteristics and outcomes between recipients of grafts from HTN and non-HTN donors. Kaplan-Meier and multivariate Cox regression models were used in assessing patient survival...
May 24, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28544502/cytomegalovirus-reactivation-posthematopoietic-stem-cell-transplantation-hsct-and-type-of-graft-a-step-toward-rationalizing-cmv-testing-and-positively-impacting-the-economics-of-hsct-in-developing-countries
#12
Ramya Uppuluri, Divya Subburaj, Dhaarani Jayaraman, Venkateswaran Vellaichamy Swaminathan, Khushnuma Mullanfiroze, Lakshman Vaidhyanathan, Revathi Raj
We aimed to determine a correlation between cytomegalovirus reactivation post hematopoeitic stem cell transplantation (post-HSCT) with the type of graft source, defining children at risk. We analyzed data on children less than 18 years of age undergoing HSCT from 2002 to May 2016 (n = 464). Correlation between reactivation and graft source was analyzed statistically. Reactivation occurred in 3% of children with matched-related donor (MRD) transplants, 33.3% with unrelated peripheral blood stem cells, 17.4% with unrelated cords, and 36...
May 22, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28544322/in-vitro-skin-expansion-wound-healing-assessment
#13
Peter M Prim, Han Su Kim, Lindsey E Shapiro, Jae Sung Lee, James H Kaan, John D Jackson, James J Yoo, Anthony Atala, Sang Jin Lee
For treatments requiring split-thickness skin grafts, it is preferable to mesh the grafts. This reduces the amount of excised skin and covers more wound area. The mesh technique, however, destroys surface continuity, which results in scarring. Strain-based bioreactors, on the other hand, have successfully expanded split-thickness skin grafts in vitro within a 7-day period, increasing graft coverage. After in vitro expansion, the expanded skin grafts were tested in a porcine full-thickness excisional wound model...
May 24, 2017: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/28544287/fast-clearable-nanocarriers-conducting-chemo-photothermal-combination-therapy-to-inhibit-recurrence-of-malignant-tumors
#14
Lingzhi Zhao, Wei Yuan, Huijun Phoebe Tham, Hongzhong Chen, Pengyao Xing, Huijing Xiang, Xin Yao, Xiaochen Qiu, Yu Dai, Liangliang Zhu, Fuyou Li, Yanli Zhao
Inhomogeneous heating by photothermal therapy (PTT) during cancer treatment often results in the recurrence of tumors. Thus, integrating PTT with chemotherapy (CHT) may provide a complementary treatment for enhanced therapeutic efficiency. Herein, this study develops a hollow structured polymer-silica nanohybrid (HPSN) as a nanocarrier to simultaneously deliver the anticancer drug paclitaxel and photothermal agent palladium phthalocyanine to tumors through enhanced permeation and the retention effect. A combinational CHT/PTT therapy on mice bearing aggressive tumor grafts is conducted...
May 24, 2017: Small
https://www.readbyqxmd.com/read/28544242/percutaneous-thoracic-aortic-aneurysm-repair-through-transcaval-aortic-access
#15
Zaher Fanari, Sumaya Hammami, Nilesh J Goswami, Jeffrey A Goldstein
Transcaval aortic access has been used for deployment of transcatheter aortic valves in patients in whom conventional arterial approaches are not feasible. This access can be vital in other situation when large bore access is needed. We described a case of 65-year-old man who had large thoracic descending aortic aneurysm with diffuse bilateral iliac disease precluding the arterial access required for the procedure. The patient underwent successful transcaval access with placement of 22-Fr balloon expandable sheath followed with successful deployments of 32 mm × 32 mm × 150 mm Valiant stent graft (Medtronic, Minneapolis, MN)...
May 22, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28544131/sclerocorneal-graft-and-sequential-removal-of-melted-cornea-after-severe-corneal-burn-with-perforation
#16
Anja Viestenz, Berthold Seitz, Hans-Gert Struck, Arne Viestenz
INTRODUCTION: Corneal burn grade IV usually leads to blindness. Several different surgical techniques remain challenging owing to the extensive tissue damage. Here, we introduce a novel technique with a 15 mm corneoscleral and limbal homologous graft combined with sequential autologous corneal removal ab interno, with a vitrectomy probe to save the anterior chamber angle. In vivo anatomy with optical coherence tomography is the surgical key. METHOD: A large 15 mm sclerocorneal graft is sutured on top of the remainder of the destroyed cornea and sclera after removal of the epithelium and conjunctiva, with anterior synechiolysis if necessary, peripheral iridectomy and conjunctivoplasty...
May 22, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28544118/application-of-bottlebrush-block-copolymers-as-photonic-crystals
#17
REVIEW
Allegra L Liberman-Martin, Crystal K Chu, Robert H Grubbs
Brush block copolymers are a class of comb polymers that feature polymeric side chains densely grafted to a linear backbone. These polymers display interesting properties due to their dense functionality, low entanglement, and ability to rapidly self-assemble to highly ordered nanostructures. The ability to prepare brush polymers with precise structures has been enabled by advancements in controlled polymerization techniques. This Feature Article highlights the development of brush block copolymers as photonic crystals that can reflect visible to near-infrared wavelengths of light...
May 22, 2017: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/28544101/belatacept-combined-with-transient-calcineurin-inhibitor-therapy-prevents-rejection-and-promotes-improved-long-term-renal-allograft-function
#18
A B Adams, J Goldstein, C Garrett, R Zhang, R E Patzer, K A Newell, N A Turgeon, A S Chami, A Guasch, A D Kirk, S O Pastan, T C Pearson, C P Larsen
Belatacept, a T cell costimulation-blocker demonstrated superior renal function, lower cardiovascular risk, and improved graft/patient survival in renal transplant recipients. Despite the potential benefits, adoption of belatacept has been limited in part due to concerns regarding higher rates and grades of acute rejection in clinical trials. Since July 2011 we have utilized belatacept-based immunosuppression regimens in clinical practice. In this retrospective analysis of 745 patients undergoing renal transplantation at our center, we compared patients treated with belatacept (n=535) to a historical cohort receiving a tacrolimus-based protocol (n=205)...
May 23, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28544075/dual-kidney-transplant-techniques-a-systematic-review
#19
Annelise Cocco, Sara Shahrestani, Nicholas Cocco, Ahmer Hameed, Lawrence Yuen, Brendan Ryan, Wayne Hawthorne, Vincent Lam, Henry Pleass
BACKGROUND: Dual kidney transplantation (DKT) was developed in order to improve outcomes from transplantation of extended criteria donors (ECD). This paper examined which surgical techniques have been reported for DKT, and whether any technique had superior patient and graft survival. METHOD: Electronic databases were searched for published studies mapping to MESH terms: ''kidney or renal" AND "transplan*" AND "dual or double". Single case reports; studies of patients less than 18 years old; studies which did not describe the surgical technique; and studies that did not report patient or graft survival were excluded...
May 23, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/28543812/acetylacetonatebodipy-biscyclometalated-iridium-iii-complexes-effective-strategy-towards-smarter-fluorescent-photosensitizer-agents
#20
Maria J Ortiz, Eduardo Palao, Rebeca Sola-Llano, Andrea Tabero, Hegoi Manzano, Antonia R Agarrabeitia, Angeles Villanueva, Iñigo López-Arbeloa, Virginia Martinez-Martinez
Biscyclometalated Ir(III) complexes involving BODIPY-based ancillary ligands, where the BODIPY unit is grafted to different chelating cores (acetylacetonate for Ir-1 and Ir-2, and bipyridine for Ir-3) by the BODIPY meso position, have been synthesized and characterized. Complexes having the BODIPY moiety directly grafted to acetylacetonate (Ir-1 and Ir-2) exhibit higher absorption coefficient (ca. ε = 4.46 104 M-1 cm-1 and 3.38 104 M-1cm-1 at 517 nm and 594 nm, respectively), higher moderate-fluorescence emission (ca...
May 19, 2017: Chemistry: a European Journal
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