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https://www.readbyqxmd.com/read/28223290/nephrologists-perspectives-on-defining-and-applying-patient-centered-outcomes-in-hemodialysis
#1
Allison Tong, Wolfgang C Winkelmayer, David C Wheeler, Wim van Biesen, Peter Tugwell, Braden Manns, Brenda Hemmelgarn, Tess Harris, Sally Crowe, Angela Ju, Emma O'Lone, Nicole Evangelidis, Jonathan C Craig
BACKGROUND AND OBJECTIVES: Patient centeredness is widely advocated as a cornerstone of health care, but it is yet to be fully realized, including in nephrology. Our study aims to describe nephrologists' perspectives on defining and implementing patient-centered outcomes in hemodialysis. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Face-to-face, semistructured interviews were conducted with 58 nephrologists from 27 dialysis units across nine countries, including the United States, the United Kingdom, Australia, Austria, Belgium, Canada, Germany, Singapore, and New Zealand...
February 21, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28219061/establishing-prenatal-surgery-for-myelomeningocele-in-asia-the-singapore-consensus
#2
Tuangsit Wataganara, Suresh Seshadri, Tak Yeung Leung, Citra Matter, Monawat Ngerncham, Namtip Triyasunant, Padmakar Vidyadhar Mali, Agnhitori Biswas, Katika Nawapun, Nisarat Phithakwatchara, Alan W Flake, Mark P Johnson, Arijit Biswas, Mahesh Choolani
OBJECTIVES: The Management of Myelomeningocele Study (MOMS Trial) has inspired many fetal therapy centers (FTCs) to offer open fetal surgery for myelomeningocele (MMC). This is an initial effort to create a candidate model that can be applicable to many parts of Asia. MATERIAL AND METHODS: A limited selection of specialists from 4 established FTCs in Thailand, Hong Kong, India, and Singapore met for a round table discussion. Experts from Children's Hospital of Philadelphia (CHOP) involved in the Trial moderated the session...
February 21, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/28218288/detection-of-viral-respiratory-pathogens-in-mild-and-severe-acute-respiratory-infections-in-singapore
#3
Lili Jiang, Vernon Jian Ming Lee, Lin Cui, Raymond Lin, Chyi Lin Tan, Linda Wei Lin Tan, Wei-Yen Lim, Yee-Sin Leo, Louie Low, Martin Hibberd, Mark I-Cheng Chen
To investigate the performance of laboratory methods and clinical case definitions in detecting the viral pathogens for acute respiratory infections (ARIs) from a prospective community cohort and hospital inpatients, nasopharyngeal swabs from cohort members reporting ARIs (community-ARI) and inpatients admitted with ARIs (inpatient-ARI) were tested by Singleplex Real Time-Polymerase Chain Reaction (SRT-PCR), multiplex RT-PCR (MRT-PCR) and pathogen-chip system (PathChip) between April 2012 and December 2013...
February 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28215256/the-association-between-chronotype-and-sleep-problems-in-preschool-children
#4
Nur K Jafar, Elaine K H Tham, Derric Z H Eng, Daniel Y T Goh, Oon-Hoe Teoh, Yung S Lee, Lynette Pei-Chi Shek, Fabian Yap, Yap Seng Chong, Michael J Meaney, Joshua J Gooley, Birit F P Broekman
OBJECTIVE: Adolescents and adults who are evening-types exhibit shorter sleep duration and more sleep problems than individuals with an earlier chronotype. We hypothesized that already at a preschool age, evening-types would exhibit more sleep problems relative to children who are morning or intermediate chronotypes. The aim of this study was to examine the association between chronotype and sleep problems among preschool children. METHODS: We studied a subset of typically-developing 4...
February 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28214752/metabolic-syndrome-and-cardiovascular-risk-among-institutionalized-patients-with-schizophrenia-receiving-long-term-tertiary-care
#5
Lee Seng Esmond Seow, Siow Ann Chong, Peizhi Wang, Saleha Shafie, Hui Lin Ong, Mythily Subramaniam
BACKGROUND: Metabolic syndrome (MetS) and cardiovascular risk are highly prevalent among individuals with schizophrenia. This study aimed to determine the cardiometabolic profile and the associated risk factors in a group of institutionalized patients with schizophrenia or schizoaffective disorder receiving prolonged hospital care in the only tertiary psychiatric institution in Singapore. METHODS: Patients residing in long stay wards who were hospitalized for a minimum period of 1year were recruited...
February 2, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28214237/knowledge-attitudes-and-preferences-of-advance-decisions-end-of-life-care-and-place-of-care-and-death-in-hong-kong-a%C3%A2-population-based-telephone-survey-of-1067-adults
#6
Roger Yat-Nork Chung, Eliza Lai-Yi Wong, Nicole Kiang, Patsy Yuen-Kwan Chau, Janice Y C Lau, Samuel Yeung-Shan Wong, Eng-Kiong Yeoh, Jean W Woo
OBJECTIVES: According to the 2015 Quality of Death Index published by the Intelligence Unit of the Economist, Hong Kong is ranked 22nd in terms of quality of palliative care in the world, behind many other major developed countries in Asia, including Taiwan, Singapore, Japan, and South Korea. The objectives of the present study were to describe the knowledge, attitude, and preferences of the general Hong Kong adult population across different age groups regarding end-of-life (EOL) care decisions, place of care and death, as well as advance directive (AD)...
February 14, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28213204/a-description-of-an-obesogenic-eating-style-that-promotes-higher-energy-intake-and-is-associated-with-greater-adiposity-in-4-5year-old-children-results-from-the-gusto-cohort
#7
Anna Fogel, Ai Ting Goh, Lisa R Fries, Suresh Anand Sadananthan, S Sendhil Velan, Navin Michael, Mya Thway Tint, Marielle Valerie Fortier, Mei Jun Chan, Jia Ying Toh, Yap-Seng Chong, Kok Hian Tan, Fabian Yap, Lynette P Shek, Michael J Meaney, Birit F P Broekman, Yung Seng Lee, Keith M Godfrey, Mary Foong Fong Chong, Ciarán G Forde
Recent findings confirm that faster eating rates support higher energy intakes within a meal and are associated with increased body weight and adiposity in children. The current study sought to identify the eating behaviours that underpin faster eating rates and energy intake in children, and to investigate their variations by weight status and other individual differences. Children (N=386) from the Growing Up in Singapore towards Healthy Outcomes (GUSTO) cohort took part in a video-recorded ad libitum lunch at 4...
February 14, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28212409/pathogenic-waterborne-free-living-amoebae-an-update-from-selected-southeast-asian-countries
#8
Mohamad Azlan Abdul Majid, Tooba Mahboob, Brandon G J Mong, Narong Jaturas, Reena Leeba Richard, Tan Tian-Chye, Anusorn Phimphila, Panomphanh Mahaphonh, Kyaw Nyein Aye, Wai Lynn Aung, Joon Chuah, Alan D Ziegler, Atipat Yasiri, Nongyao Sawangjaroen, Yvonne A L Lim, Veeranoot Nissapatorn
Data on the distribution of free-living amoebae is still lacking especially in Southeast Asian region. The aquatic environment revealed a high occurrence of free-living amoebae (FLA) due to its suitable condition and availability of food source, which subsequently causes infection to humans. A total of 94 water samples consisted of both treated and untreated from Laos (31), Myanmar (42), and Singapore (21) were investigated for the presence of pathogenic FLA. Each water sample was filtered and cultured onto non-nutrient agar seeded with live suspension of Escherichia coli and incubated at room temperature...
2017: PloS One
https://www.readbyqxmd.com/read/28210744/comment-on-zika-in-singapore-insights-from-one-health-and-social-medicine
#9
John H Lange, Luca Cegolon
No abstract text is available yet for this article.
February 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28209196/personal-values-marketing-attitudes-and-nutrition-trust-are-associated-with-patronage-of-convenience-food-outlets-in-the-asia-pacific-region-a-cross-sectional-study
#10
Breanna De Jong, Anthony Worsley, Wei Chun Wang, Rani Sarmugam, Quynh Pham, Judhiastuty Februhartanty, Stacey Ridley
BACKGROUND: An online cross-sectional survey examined the relationships between the demographic characteristics, personal values, trust in sources of nutrition information and the use of convenience food outlets among middle-class household food providers in the Asia-Pacific region. METHODS: The survey was administered to 3945 household food providers in Melbourne, Singapore, Shanghai, Vietnam and Indonesia in late 2013. Information about demographics, personal values, trust in sources of nutrition information and use of convenience food outlets was elicited...
February 16, 2017: Journal of Health, Population, and Nutrition
https://www.readbyqxmd.com/read/28208170/optical-coherence-tomographic-angiography-in-type-2-diabetes-and-diabetic-retinopathy
#11
Daniel Shu Wei Ting, Gavin Siew Wei Tan, Rupesh Agrawal, Yasuo Yanagi, Nicole Ming Sie, Chee Wai Wong, Ian Yew San Yeo, Shu Yen Lee, Chui Ming Gemmy Cheung, Tien Yin Wong
Importance: Optical coherence tomographic angiography (OCT-A) is able to visualize retinal microvasculature without the need for injection of fluorescein contrast dye. Nevertheless, it is only able to capture a limited view of macula and does not show leakage. Objectives: To evaluate the retinal microvasculature using OCT-A in patients with type 2 diabetes as well as the association of OCT-A characteristics with diabetic retinopathy (DR) and systemic risk factors...
February 16, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28207545/primary-hypothyroidism-in-the-community-lower-daily-dosages-of-levothyroxine-replacement-therapy-for-asian-patients
#12
Ngiap Chuan Tan, Rong Quan Chew, Yi Ling Eileen Koh, Reena Chandini Subramanian, Usha Sankari, Meykkumar Meyappan, Li Wei Cho
The goal of treatment in patients with primary hypothyroidism is to attain euthyroidism guided by the stipulated thyroid-stimulating hormone (TSH) levels range so as to minimize any potential long-term adverse effects. However, various factors may result in their Levothyroxine (T4) under and over-replacement.Our study aimed to evaluate the mean daily dose of L-T4 replacement for Asian patients with primary hypothyroidism. The secondary aims were to determine the proportion of those who were either over or under-replaced, and the factors associated with their thyroid function status and replacement adherence...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28205148/ocular-autoimmune-systemic-inflammatory-infectious-study-oasis-report-4-analysis-and-outcome-of-scleritis-in-an-east-asian-population
#13
Muhammad Amir Bin Ismail, Rachel Hui Fen Lim, Helen Mi Fang, Elizabeth Poh Ying Wong, Ho Su Ling, Wee Kiak Lim, Stephen C Teoh, Rupesh Agrawal
BACKGROUND: The purpose of this study is to evaluate the spectrum of scleritis from database of Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) at a tertiary eye referral eye institute in Singapore. Clinical records of 120 patients with scleritis from a database of 2200 patients from Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) were reviewed. RESULTS: 56.6% were females, with a mean age of 48.6 ± 15.9 years. 75 (62.5%) had diffuse anterior scleritis, 25 (20...
December 2017: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/28202383/a-randomized-controlled-trial-of-screening-risk-modification-and-physical-therapy-to-prevent-falls-among-the-elderly-recently-discharged-from-the-emergency-department-to-the-community-the-steps-to-avoid-falls-in-the-elderly-study
#14
David B Matchar, Pamela W Duncan, Christopher T C Lien, Marcus Eng Hock Ong, Mina Lee, Fei Gao, Rita Sim, Kirsten Eom
OBJECTIVE: To evaluate the effectiveness of a multifactorial, tailored program of physical therapy to reduce the occurrence of falls among a heterogeneous group of high-risk elderly Singaporeans recently discharged from the Emergency Department (ED). DESIGN: Randomized controlled trial. SETTING: Communities in Central and East regions in Singapore. PARTICIPANTS: 354 adults aged at least 65 years who were seen at ED for a fall or fall-related injuries and discharged home...
February 12, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28198787/serologic-responses-after-hepatitis-b-vaccination-in-preterm-infants-born-to-hepatitis-b-surface-antigen-positive-mothers-singapore-experience
#15
Tan Xt Christelle, Chan Si Min, Le Ye Lee, Christina Ong, Kong Boo Phua, Marion M Aw, Sharon Saw, Guan Huei Lee, Franco Wong, Koh Cheng Thoon
BACKGROUND: The Advisory Committee on Immunization Practices (ACIP) recommends a 4-dose vaccination schedule for preterm low birth weight infants (<2kg) and a 3-dose vaccination schedule for preterm infants (≥2kg) born to hepatitis B surface antigen (HBsAg) positive mothers. However, data remain limited for these high risk infants and the optimal dosing schedule in Asia is not well established. AIM: We aimed to evaluate the serologic vaccine responses in preterm infants born to HBsAg positive mothers using current vaccination guidelines...
February 13, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28196785/clinical-and-socio-demographic-predictors-of-home-hospice-patients-dying-at-home-a-retrospective-analysis-of-hospice-care-association-s-database-in-singapore
#16
Yee Song Lee, Ramaswamy Akhileswaran, Marcus Ong Eng Hock, Win Wah, David Hui, Sheryl Hui-Xian Ng, Gerald Koh
CONTEXT: Hospice care can be delivered in different settings but many patients choose to receive it at home because of familiar surroundings. Despite their preferences, not every home hospice patient manages to die at home. OBJECTIVE: To examine the independent factors associated with home hospice patient dying at home. METHOD: Retrospective analysis of Hospice Care Association (HCA)'s database. HCA is the largest home hospice provider in Singapore...
February 11, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28193663/results-from-a-patient-based-health-education-intervention-in-reducing-antibiotic-use-for-acute-upper-respiratory-tract-infections-in-the-private-sector-primary-care-setting-in-singapore
#17
Magdalene Hui Min Lee, Darius Shaw Teng Pan, Joyce Huixin Huang, Mark I-Cheng Chen, Joash Wen Chen Chong, Ee Hui Goh, Lili Jiang, Yee Sin Leo, Tau Hong Lee, Chia Siong Wong, Victor Weng Keong Loh, Fong Seng Lim, Adrian Zhongxian Poh, Tat Yean Tham, Wei Mon Wong, Yue Yu
We investigated the efficacy of patient-targeted education in reducing antibiotic prescriptions for upper respiratory tract infections (URTIs) amongst adults in the private primary care setting in Singapore. Our randomized controlled trial enrolled patients aged 21 years and above presenting at GP (general practitioner) clinics with URTI symptoms for 7 days or less. Intervention arm patients were verbally educated via pamphlets about the aetiology of URTIs, role of antibiotics in treating URTIs, and consequences of inappropriate antibiotic use...
February 13, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28193259/acute-kidney-injury-increases-the-risk-of-end-stage-renal-disease-after-cardiac-surgery-in-an-asian-population-a-prospective-cohort-study
#18
Sophia Tsong Huey Chew, Roderica Rui Ge Ng, Weiling Liu, Khuan Yew Chow, Lian Kah Ti
BACKGROUND: Acute kidney injury (AKI) after cardiac surgery is associated with increased morbidity and mortality. The long-term association between AKI and end-stage renal disease (ESRD) in an Asian population is unknown. Given the high prevalence of diabetes and a younger age of presentation for cardiac surgery, it is important to track this progression of kidney disease. Therefore, we studied the long-term risk of ESRD and mortality in our Asian patients who developed AKI after cardiac surgery...
February 13, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28192631/thyroid-cytology-nuclear-versus-architectural-atypia-within-the-atypia-of-undetermined-significance-follicular-lesion-of-undetermined-significance-bethesda-category-have-significantly-different-rates-of-malignancy
#19
Tiffany Rui Xuan Gan, Min En Nga, Jeffrey Huey Yew Lum, Wendy Meihua Wong, Wee Boon Tan, Rajeev Parameswaran, Kee Yuan Ngiam
BACKGROUND: The Bethesda System for Reporting Thyroid Cytopathology is the most widely used classification system for the reporting of thyroid fine-needle aspiration cytology (FNAC) specimens. However, the "atypical" category ("atypia of undetermined significance" [AUS] or "follicular lesion of undetermined significance" [FLUS]) continues to cause diagnostic and therapeutic dilemmas. The objectives of this study were to describe the differential malignancy rates of FNACs diagnosed as AUS/FLUS based on nuclear or architectural atypia and to assess the significance of demographic and ultrasonographic features in predicting malignancy in this category...
February 13, 2017: Cancer
https://www.readbyqxmd.com/read/28192367/the-occurrence-of-enhanced-biological-phosphorus-removal-in-a-200-000-m-3-day-partial-nitration-and-anammox-activated-sludge-process-at-the-changi-water-reclamation-plant-singapore
#20
Yeshi Cao, Bee Hong Kwok, Mark C M van Loosdrecht, Glen T Daigger, Hui Yi Png, Wah Yuen Long, Chua Seng Chye, Yahya A B D Ghani
Mainstream partial nitritation and Anammox (PN/A) has been observed and studied in the step-feed activated sludge process at the Changi water reclamation plant (WRP), which is the largest WRP (800,000 m(3)/d) in Singapore. This paper presents the study results for enhanced biological phosphorus removal (EBPR) co-existing with PN/A in the activated sludge process. Both the in-situ EBPR efficiency and ex-situ activities of phosphorus release and uptake were high. The phosphorus accumulating organisms were dominant, with little presence of glycogen accumulating organisms in the activated sludge...
February 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
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