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"Katz, J"

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https://www.readbyqxmd.com/read/27910656/the-design-of-the-optical-thomson-scattering-diagnostic-for-the-national-ignition-facility
#1
P S Datte, J S Ross, D H Froula, K D Daub, J Galbraith, S Glenzer, B Hatch, J Katz, J Kilkenny, O Landen, D Manha, A M Manuel, W Molander, D Montgomery, J Moody, G F Swadling, J Weaver
The National Ignition Facility (NIF) is a 192 laser beam facility designed to support the Stockpile Stewardship, High Energy Density and Inertial Confinement Fusion (ICF) programs. We report on the design of an Optical Thomson Scattering (OTS) diagnostic that has the potential to transform the community's understanding of NIF hohlraum physics by providing first principle, local, time-resolved measurements of under-dense plasma conditions. The system design allows operation with different probe laser wavelengths by manual selection of the appropriate beam splitter and gratings before the shot...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910648/simulated-performance-of-the-optical-thomson-scattering-diagnostic-designed-for-the-national-ignition-facility
#2
J S Ross, P Datte, L Divol, J Galbraith, D H Froula, S H Glenzer, B Hatch, J Katz, J Kilkenny, O Landen, A M Manuel, W Molander, D S Montgomery, J D Moody, G Swadling, J Weaver
An optical Thomson scattering diagnostic has been designed for the National Ignition Facility to characterize under-dense plasmas. We report on the design of the system and the expected performance for different target configurations. The diagnostic is designed to spatially and temporally resolve the Thomson scattered light from laser driven targets. The diagnostic will collect scattered light from a 50 × 50 × 200 μm volume. The optical design allows operation with different probe laser wavelengths. A deep-UV probe beam (λ0 = 210 nm) will be used to Thomson scatter from electron plasma densities of ∼5 × 10(20) cm(-3) while a 3ω probe will be used for plasma densities of ∼1 × 10(19) cm(-3)...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910508/a-particle-x-ray-temporal-diagnostic-pxtd-for-studies-of-kinetic-multi-ion-effects-and-ion-electron-equilibration-rates-in-inertial-confinement-fusion-plasmas-at-omega-invited
#3
H Sio, J A Frenje, J Katz, C Stoeckl, D Weiner, M Bedzyk, V Glebov, C Sorce, M Gatu Johnson, H G Rinderknecht, A B Zylstra, T C Sangster, S P Regan, T Kwan, A Le, A N Simakov, W T Taitano, L Chacòn, B Keenan, R Shah, G Sutcliffe, R D Petrasso
A Particle X-ray Temporal Diagnostic (PXTD) has been implemented on OMEGA for simultaneous time-resolved measurements of several nuclear products as well as the x-ray continuum produced in High Energy Density Plasmas and Inertial Confinement Fusion implosions. The PXTD removes systematic timing uncertainties typically introduced by using multiple instruments, and it has been used to measure DD, DT, D(3)He, and T(3)He reaction histories and the emission history of the x-ray core continuum with relative timing uncertainties within ±10-20 ps...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910493/plasma-characterization-using-ultraviolet-thomson-scattering-from-ion-acoustic-and-electron-plasma-waves-invited
#4
R K Follett, J A Delettrez, D H Edgell, R J Henchen, J Katz, J F Myatt, D H Froula
Collective Thomson scattering is a technique for measuring the plasma conditions in laser-plasma experiments. Simultaneous measurements of ion-acoustic and electron plasma-wave spectra were obtained using a 263.25-nm Thomson-scattering probe beam. A fully reflective collection system was used to record light scattered from electron plasma waves at electron densities greater than 10(21) cm(-3), which produced scattering peaks near 200 nm. An accurate analysis of the experimental Thomson-scattering spectra required accounting for plasma gradients, instrument sensitivity, optical effects, and background radiation...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910314/a-pulse-front-tilt-compensated-streaked-optical-spectrometer-with-high-throughput-and-picosecond-time-resolution
#5
J Katz, R Boni, R Rivlis, C Muir, D H Froula
A high-throughput, broadband optical spectrometer coupled to the Rochester optical streak system equipped with a Photonis P820 streak tube was designed to record time-resolved spectra with 1-ps time resolution. Spectral resolution of 0.8 nm is achieved over a wavelength coverage range of 480 to 580 nm, using a 300-groove/mm diffraction grating in conjunction with a pair of 225-mm-focal-length doublets operating at an f/2.9 aperture. Overall pulse-front tilt across the beam diameter generated by the diffraction grating is reduced by preferentially delaying discrete segments of the collimated input beam using a 34-element reflective echelon optic...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27497697/cross-cultural-validation-of-the-icoap-and-physical-function-short-forms-of-the-hoos-and-koos-in-a-multi-country-study-of-patients-with-hip-and-knee-osteoarthritis
#6
S P Mehta, A Sankar, V Venkataramanan, L S Lohmander, J N Katz, G A Hawker, L Gossec, E M Roos, J-F Maillefert, M Kloppenburg, M Dougados, A M Davis
OBJECTIVE: To evaluate the internal consistency and construct validity of the Physical Function short-forms for the Hip and Knee Injury Osteoarthritis Outcome Scores (HOOS-PS/KOOS-PS) and the Intermittent and Constant Osteoarthritis Pain (ICOAP) in a nine country study of patients consulting for total hip or knee replacement (THR or TKR). METHODS: Patients completed HOOS-PS or KOOS-PS, ICOAP and Western Ontario and McMaster Universities' Osteoarthritis Index (WOMAC) pain and physical function subscales at their consultation visit...
August 4, 2016: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/27465702/validation-of-an-obstetric-fistula-screening-questionnaire-in-rural-nepal-a-community-based-cross-sectional-and-nested-case-control-study-with-clinical-examination
#7
Ccg Chen, D Barry, S K Khatry, E M Klasen, M Singh, S C LeClerq, J Katz, J M Tielsch, L C Mullany
OBJECTIVE: To validate a symptom-based fistula screening questionnaire and estimate obstetric fistula (OF) prevalence in rural Nepal. DESIGN: Cross-sectional and nested case-control study. SETTING: Sarlahi District, Nepal. POPULATION: Parous, reproductive age women. METHODS: The questionnaire assessed symptoms of vesicovaginal and rectovaginal fistula (VVF and RVF, respectively), stress and urge urinary incontinence (SUI and UUI, respectively), fecal incontinence (FI), and included interviewer observations on the smell and presence of urine and/or stool...
July 27, 2016: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27421978/factors-associated-with-fractures-in-hiv-infected-persons-which-factors-matter
#8
L Gedmintas, E A Wright, Y Dong, E Lehmann, J N Katz, D H Solomon, E Losina
: This study aims to determine what factors are associated with increased risk of fracture among patients with HIV, in particular whether an important medication used to treat HIV, tenofovir, is associated with fracture. Our study found that while co-infection with hepatitis C and markers of HIV severity were associated with fracture, tenofovir was not. INTRODUCTION: Growing evidence suggests that tenofovir disoproxil fumarate decreases bone density among patients with HIV, but there are conflicting reports as to whether this decrease in bone density translates to higher fracture risk...
July 15, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27341238/experimental-evidence-of-the-collective-brillouin-scattering-of-multiple-laser-beams-sharing-acoustic-waves
#9
C Neuville, V Tassin, D Pesme, M-C Monteil, P-E Masson-Laborde, C Baccou, P Fremerye, F Philippe, P Seytor, D Teychenné, W Seka, J Katz, R Bahr, S Depierreux
The indirect-drive scheme to inertial confinement fusion uses a large number of laser beams arranged in a symmetric angular distribution. Collective laser plasma instabilities can therefore develop that couple all the incident laser waves located in a cone to the daughter wave growing along the cone symmetry axis [D. F. DuBois et al., Phys. Fluids B 4, 241 (1992)]. With complementary diagnostics of Thomson scattering and of the scattered light, we demonstrate the occurrence of collective stimulated Brillouin sidescattering driving collective acoustic waves in indirect-drive experiments...
June 10, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27258040/what-is-a-complex-innovation-system
#10
J Sylvan Katz
Innovation systems are sometimes referred to as complex systems, something that is intuitively understood but poorly defined. A complex system dynamically evolves in non-linear ways giving it unique properties that distinguish it from other systems. In particular, a common signature of complex systems is scale-invariant emergent properties. A scale-invariant property can be identified because it is solely described by a power law function, f(x) = kxα, where the exponent, α, is a measure of scale-invariance...
2016: PloS One
https://www.readbyqxmd.com/read/27250427/a-picosecond-beam-timing-system-for-the-omega-laser
#11
W R Donaldson, J Katz, R Huff, E M Hill, J H Kelly, J Kwiatkowski, R B Brannon, R Boni
A timing system is demonstrated for the OMEGA Laser System that guarantees all 60 beams will arrive on target simultaneously with a root mean square variability of 4 ps. The system relies on placing a scattering sphere at the target position to couple the ultraviolet light from each beam into a single photodetector.
May 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27250417/neutron-temporal-diagnostic-for-high-yield-deuterium-tritium-cryogenic-implosions-on-omega
#12
C Stoeckl, R Boni, F Ehrne, C J Forrest, V Yu Glebov, J Katz, D J Lonobile, J Magoon, S P Regan, M J Shoup, A Sorce, C Sorce, T C Sangster, D Weiner
A next-generation neutron temporal diagnostic (NTD) capable of recording high-quality data for the highest anticipated yield cryogenic deuterium-tritium (DT) implosion experiments was recently installed at the Omega Laser Facility. A high-quality measurement of the neutron production width is required to determine the hot-spot pressure achieved in inertial confinement fusion experiments-a key metric in assessing the quality of these implosions. The design of this NTD is based on a fast-rise-time plastic scintillator, which converts the neutron kinetic energy to 350- to 450-nm-wavelength light...
May 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27127973/two-plasmon-decay-mitigation-in-direct-drive-inertial-confinement-fusion-experiments-using-multilayer-targets
#13
R K Follett, J A Delettrez, D H Edgell, V N Goncharov, R J Henchen, J Katz, D T Michel, J F Myatt, J Shaw, A A Solodov, C Stoeckl, B Yaakobi, D H Froula
Multilayer direct-drive inertial-confinement-fusion targets are shown to significantly reduce two-plasmon decay (TPD) driven hot-electron production while maintaining high hydrodynamic efficiency. Implosion experiments on the OMEGA laser used targets with silicon layered between an inner beryllium and outer silicon-doped plastic ablator. A factor-of-5 reduction in hot-electron generation (>50  keV) was observed in the multilayer targets relative to pure CH targets. Three-dimensional simulations of the TPD-driven hot-electron production using a laser-plasma interaction code (lpse) that includes nonlinear and kinetic effects show good agreement with the measurements...
April 15, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27105136/similar-white-matter-but-opposite-grey-matter-changes-in-schizophrenia-and-high-functioning-autism
#14
J Katz, M-A d'Albis, J Boisgontier, C Poupon, J-F Mangin, P Guevara, D Duclap, N Hamdani, J Petit, D Monnet, P Le Corvoisier, M Leboyer, R Delorme, J Houenou
OBJECTIVE: High-functioning autism (HFA) and schizophrenia (SZ) are two of the main neurodevelopmental disorders, sharing several clinical dimensions and risk factors. Their exact relationship is poorly understood, and few studies have directly compared both disorders. Our aim was thus to directly compare neuroanatomy of HFA and SZ using a multimodal MRI design. METHODS: We scanned 79 male adult subjects with 3T MRI (23 with HFA, 24 with SZ and 32 healthy controls, with similar non-verbal IQ)...
July 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/26933094/changes-in-pain-sensitivity-and-pain-modulation-during-oral-opioid-treatment-the-impact-of-negative-affect
#15
R R Edwards, A J Dolman, E Michna, J N Katz, S S Nedeljkovic, D Janfaza, Z Isaac, M O Martel, R N Jamison, A D Wasan
OBJECTIVE: Opioids are frequently prescribed for chronic low back pain (CLBP), but there are broad individual differences in the benefits and risks of opioid therapy, including the development opioid-induced hyperalgesia. This study examined quantitative sensory testing (QST) data among a group of CLBP patients undergoing sustained oral opioid treatment. We investigated whether individual differences in psychological characteristics were related to opioid-induced changes in pain perception and pain modulation...
October 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/26782054/sexual-divergence-in-microtubule-function-the-novel-intranasal-microtubule-targeting-skip-normalizes-axonal-transport-and-enhances-memory
#16
N Amram, G Hacohen-Kleiman, S Sragovich, A Malishkevich, J Katz, O Touloumi, R Lagoudaki, N C Grigoriadis, E Giladi, A Yeheskel, M Pasmanik-Chor, Y Jouroukhin, I Gozes
Activity-dependent neuroprotective protein (ADNP), essential for brain formation, is a frequent autism spectrum disorder (ASD)-mutated gene. ADNP associates with microtubule end-binding proteins (EBs) through its SxIP motif, to regulate dendritic spine formation and brain plasticity. Here, we reveal SKIP, a novel four-amino-acid peptide representing an EB-binding site, as a replacement therapy in an outbred Adnp-deficient mouse model. We discovered, for the first time, axonal transport deficits in Adnp(+/-) mice (measured by manganese-enhanced magnetic resonance imaging), with significant male-female differences...
October 2016: Molecular Psychiatry
https://www.readbyqxmd.com/read/26582851/pregabalin-reduces-postoperative-opioid-consumption-and-pain-for-1-week-after-hospital-discharge-but-does-not-affect-function-at-6-weeks-or-3-months-after-total-hip-arthroplasty
#17
RANDOMIZED CONTROLLED TRIAL
H Clarke, G M Pagé, C J L McCartney, A Huang, P Stratford, J Andrion, D Kennedy, I T Awad, J Gollish, J Kay, J Katz
BACKGROUND: This study examined whether a perioperative regimen of pregabalin added to celecoxib improved pain scores and functional outcomes postdischarge up to 3 months after total hip arthroplasty (primary outcome) and acute postoperative pain and adverse effects (secondary outcomes). METHODS: One hundred and eighty-four patients were enrolled in a randomized, double-blind, placebo-controlled study. Two hours before receiving a spinal anaesthetic and undergoing surgery, patients received celecoxib 400 mg p...
December 2015: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/26533539/clinical-characteristics-and-patterns-of-care-among-patients-with-genotype-1-g1-hepatitis-c-virus-in-europe-eu
#18
S Narayanan, A Wilson, J Katz, S Fernando
No abstract text is available yet for this article.
November 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/26316262/brief-report-cartilage-thickness-change-as-an-imaging-biomarker-of-knee-osteoarthritis-progression-data-from-the-foundation-for-the-national-institutes-of-health-osteoarthritis-biomarkers-consortium
#19
MULTICENTER STUDY
F Eckstein, J E Collins, M C Nevitt, J A Lynch, V B Kraus, J N Katz, E Losina, W Wirth, A Guermazi, F W Roemer, D J Hunter
OBJECTIVE: To investigate the association of cartilage thickness change over 24 months, as determined by magnetic resonance imaging (MRI), with knee osteoarthritis (OA) progression at 24-48 months. METHODS: This nested case-control study included 600 knees with a baseline Kellgren/Lawrence (K/L) grade of 1-3 from 600 Osteoarthritis Initiative (OAI) participants. Case knees (n = 194) had both medial tibiofemoral radiographic joint space loss (≥0.7 mm) and a persistent increase in the Western Ontario and McMaster Universities Osteoarthritis Index pain score (≥9 on a 0-100 scale) 24-48 months from baseline...
December 2015: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/25958770/prevalence-of-cryptococcal-antigenuria-at-initial-hiv-diagnosis-in-kwazulu-natal
#20
P K Drain, J M Kleene, S M Coleman, E Losina, J N Katz, J Giddy, D Ross, K A Freedberg, I V Bassett
OBJECTIVES: The World Health Organization (WHO) recommends screening HIV-infected people for cryptococcal antigens to identify cryptococcosis, a major cause of AIDS-related deaths. As the burden of cryptococcosis is unknown in South Africa's KwaZulu-Natal province, we assessed the cryptococcal antigenuria prevalence among newly diagnosed HIV-infected adults there. METHODS: We conducted a cross-sectional study of newly diagnosed HIV-infected adults who received voluntary HIV testing in an out-patient clinic...
November 2015: HIV Medicine
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