keyword
MENU ▼
Read by QxMD icon Read
search

Fragility index

keyword
https://www.readbyqxmd.com/read/27907023/field-trials-reveal-ecotype-specific-responses-to-mycorrhizal-inoculation-in-rice
#1
Abdala Gamby Diedhiou, Fatou Kine Mbaye, Daouda Mbodj, Mathieu Ndigue Faye, Sarah Pignoly, Ibrahima Ndoye, Koffi Djaman, Souleymane Gaye, Aboubacry Kane, Laurent Laplaze, Baboucarr Manneh, Antony Champion
The overuse of agricultural chemicals such as fertilizer and pesticides aimed at increasing crop yield results in environmental damage, particularly in the Sahelian zone where soils are fragile. Crop inoculation with beneficial soil microbes appears as a good alternative for reducing agricultural chemical needs, especially for small farmers. This, however, requires selecting optimal combinations of crop varieties and beneficial microbes tested in field conditions. In this study, we investigated the response of rice plants to inoculation with arbuscular mycorrhizal fungi (AMF) and plant growth promoting bacteria (PGPB) under screenhouse and field conditions in two consecutive seasons in Senegal...
2016: PloS One
https://www.readbyqxmd.com/read/27903339/-effect-of-goal-directed-haemodynamic-management-on-the-postoperative-outcome-in-elderly-patients-with-fragile-cardiac-function-undergoing-abdominal-surgery
#2
L S Zheng, E W Gu, X H Peng, L Zhang, Y Y Cao
Objective: To investigate the effect of goal-directed haemodynamic management based on stroke volume variation (SVV), cardiac index (CI) and mean arterial blood pressure (MAP) on the postoperative outcome in elderly patients with fragile cardiac function undergoing gastrointestinal surgery. Methods: Ninety patients with fragile cardiac function, aged 65-90 years old, ASAⅡ or Ⅲ, NYHA Ⅱor Ⅲ, scheduled for abdominal surgery were enrolled in this study.The patients were randomly assigned to two groups: Experience anesthesia group (group E, n=45) and goal-directed hemodynamic management group (G group, n=45)...
November 22, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27895038/the-fragility-of-statistically-significant-findings-from-randomized-trials-in-sports-surgery-a-systematic-survey
#3
Moin Khan, Nathan Evaniew, Mark Gichuru, Anthony Habib, Olufemi R Ayeni, Asheesh Bedi, Michael Walsh, P J Devereaux, Mohit Bhandari
BACKGROUND: High-quality, evidence-based orthopaedic care relies on the generation and translation of robust research evidence. The Fragility Index is a novel method for evaluating the robustness of statistically significant findings from randomized controlled trials (RCTs). It is defined as the minimum number of patients in 1 arm of a trial that would have to change status from a nonevent to an event to alter the results of the trial from statistically significant to nonsignificant. PURPOSE: To calculate the Fragility Index of statistically significant results from clinical trials in sports medicine and arthroscopic surgery to characterize the robustness of the RCTs in these fields...
November 28, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27886481/correlation-between-fragility-and-the-arrhenius-crossover-phenomenon-in-metallic-molecular-and-network-liquids
#4
Abhishek Jaiswal, Takeshi Egami, K F Kelton, Kenneth S Schweizer, Yang Zhang
We report the observation of a distinct correlation between the kinetic fragility index m and the reduced Arrhenius crossover temperature θ_{A}=T_{A}/T_{g} in various glass-forming liquids, identifying three distinguishable groups. In particular, for 11 glass-forming metallic liquids, we universally observe a crossover in the mean diffusion coefficient from high-temperature Arrhenius to low-temperature super-Arrhenius behavior at approximately θ_{A}≈2 which is in the stable liquid phases. In contrast, for fragile molecular liquids, this crossover occurs at much lower θ_{A}≈1...
November 11, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27852598/frailty-and-bone-health-in-european-men
#5
Michael J Cook, Alexander Oldroyd, Stephen R Pye, Kate A Ward, Evelien Gielen, Rathi Ravindrarajah, Judith E Adams, David M Lee, Gyorgy Bartfai, Steven Boonen, Felipe Casanueva, Gianni Forti, Aleksander Giwercman, Thang S Han, Ilpo T Huhtaniemi, Krzysztof Kula, Michael E Lean, Neil Pendleton, Margus Punab, Dirk Vanderschueren, Frederick C Wu, Terence W O'Neill
BACKGROUND: frailty is associated with an increased risk of fragility fractures. Less is known, however, about the association between frailty and bone health. METHODS: men aged 40-79 years were recruited from population registers in eight European centres for participation in the European Male Aging Study. Subjects completed a comprehensive assessment which included quantitative ultrasound (QUS) scan of the heel (Hologic-SAHARA) and in two centres, dual-energy bone densitometry (dual-energy x-ray absorptiometry, DXA)...
November 16, 2016: Age and Ageing
https://www.readbyqxmd.com/read/27836532/controlled-pilot-study-of-high-impact-low-frequency-exercise-on-bone-loss-and-vital-sign-stabilization-in-adolescents-with-eating-disorders
#6
Susanne P K Martin, Laura K Bachrach, Neville H Golden
PURPOSE: Adolescents with anorexia nervosa (AN) face an increased lifetime risk of bone fragility. This randomized controlled study examined the efficacy and safety of a high-impact activity program on markers of bone turnover and stabilization of vital signs (VSS). METHODS: Forty-one hospitalized adolescents with AN were randomly assigned to routine care or routine care plus 20 jumps twice daily. Bone markers were measured at baseline days 1-3 (T1), days 4-6 (T2), and days 7-9 (T3)...
November 8, 2016: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/27832795/bone-histomorphometric-changes-in-children-with-rheumatic-disorders-on-chronic-glucocorticoids
#7
Jennifer Harrington, Douglas Holmyard, Earl Silverman, Etienne Sochett, Marc Grynpas
BACKGROUND: Rheumatic diseases are associated with an increased fracture risk. The tissue level characteristics of the bone involvement in children have not been well elucidated. Our objectives were to describe the bone micro-architectural characteristics in children with rheumatic diseases on chronic glucocorticoids, and to determine associations between micro-architectural findings with clinical and radiological variables. METHODS: Children on chronic glucocorticoids for an underlying rheumatic disease were referred for evaluation of bone fragility given the presence of vertebral compression fractures...
November 10, 2016: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/27812809/geographic-variation-in-secondary-fracture-prevention-after-a-hip-fracture-during-1999-2013-a-uk-study
#8
A Shah, D Prieto-Alhambra, S Hawley, A Delmestri, J Lippett, C Cooper, A Judge, M K Javaid
: Fragility fractures of the hip have a major impact on the lives of patients and their families. This study highlights significant geographical variation in secondary fracture prevention with even the highest performing regions failing the majority of patients despite robust evidence supporting the benefits of diagnosis and treatment. INTRODUCTION: The purpose of the study is to describe the geographic variation in anti-osteoporosis drug therapy prescriptions before and after a hip fracture during 1999-2013 in the UK...
November 3, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27801641/a-systematic-review-and-economic-evaluation-of-bisphosphonates-for-the-prevention-of-fragility-fractures
#9
Sarah Davis, Marrissa Martyn-St James, Jean Sanderson, John Stevens, Edward Goka, Andrew Rawdin, Susi Sadler, Ruth Wong, Fiona Campbell, Matt Stevenson, Mark Strong, Peter Selby, Neil Gittoes
BACKGROUND: Fragility fractures are fractures that result from mechanical forces that would not ordinarily result in fracture. OBJECTIVES: To evaluate the clinical effectiveness and safety of bisphosphonates [alendronic acid (Fosamax(®) and Fosamax(®) Once Weekly, Merck Sharp & Dohme Ltd), risedronic acid (Actonel(®) and Actonel Once a Week(®), Warner Chilcott UK Ltd), ibandronic acid (Bonviva(®), Roche Products Ltd) and zoledronic acid (Aclasta(®), Novartis Pharmaceuticals UK Ltd)] for the prevention of fragility fracture and to assess their cost-effectiveness at varying levels of fracture risk...
October 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27776984/understanding-mortality-of-femoral-fractures-following-low-impact-trauma-in-persons-with-and-without-care-need
#10
Tobias Bluhmki, Raphael Simon Peter, Kilian Rapp, Hans-Helmut König, Clemens Becker, Ivonne Lindlbauer, Dietrich Rothenbacher, Jan Beyersmann, Gisela Büchele
OBJECTIVES: Persons with osteoporotic fracture history are subject to an increased risk for subsequent fractures and mortality. The aim of this retrospective study was to investigate the impact of a previous osteoporotic low-impact (fragility) index fracture (eg, forearm, lower leg) on mortality of a subsequent femoral fracture. DESIGN: Retrospective cohort study. PARTICIPANTS/MEASUREMENTS: Claims data of a German health insurance agency including >1...
October 21, 2016: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/27773524/the-slow-relaxation-dynamics-in-the-amorphous-pharmaceutical-drugs-cimetidine-nizatidine-and-famotidine
#11
M Teresa Viciosa, Joaquim J Moura Ramos, Hermínio P Diogo
The slow molecular mobility in the amorphous solid state of 3 active pharmaceutical drugs (cimetidine, nizatidine, and famotidine) has been studied using differential scanning calorimetry and the 2 dielectric-related techniques of dielectric relaxation spectroscopy and thermally stimulated depolarization currents. The glass-forming ability, the glass stability, and the tendency for crystallization from the equilibrium melt were investigated by differential scanning calorimetry, which also provided the characterization of the main relaxation of the 3 glass formers...
October 20, 2016: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27773370/improvement-in-osteoporosis-detection-in-a-fracture-liaison-service-with-integration-of-a-geriatric-hip-fracture-care-program
#12
Amrut Borade, Harish Kempegowda, Akhil Tawari, Michael Suk, Daniel S Horwitz
INTRODUCTION: Care gaps have been identified in the treatment of osteoporosis after the occurrence of a fragility hip fracture. HiROC (High Risk Osteoporosis Clinic) is a fracture liaison service implemented at our institution. In ProvenCare geriatric hip fracture care program at our institution pre-set orders for the inpatient HiROC consults were prescribed. We hypothesized that there will be a significant increase in the rate of enrollment of patients in the HiROC program after the integration of the pre-set orders...
December 2016: Injury
https://www.readbyqxmd.com/read/27755081/does-sample-size-matter-when-interpreting-the-fragility-index
#13
Wael Ahmed, Robert A Fowler, Victoria A McCredie
No abstract text is available yet for this article.
November 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27754806/the-effect-of-tsh-suppression-on-vertebral-trabecular-bone-scores-in-patients-with-differentiated-thyroid-carcinoma
#14
Jae Hoon Moon, Kyoung Min Kim, Tae Jung Oh, Sung Hee Choi, Soo Lim, Young Joo Park, Do Joon Park, Hak Chul Jang
DESIGN, SETTING, AND PARTICIPANTS: We conducted a retrospective cohort study including 273 postmenopausal women with DTC who had received TSH-suppressive therapy. Bone mineral density (BMD) and TBS at the lumbar spine were analyzed using dual-energy X-ray absorptiometry (DXA). Major Outcome Measure: The association between the parameters of TSH-suppressive therapy and bone parameters was investigated. RESULTS: Study subjects showed upper-normal free thyroxine (free T4) levels and suppressed TSH at DXA evaluation...
October 18, 2016: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27742808/how-robust-are-clinical-trials-in-heart-failure
#15
Kieran F Docherty, Ross T Campbell, Pardeep S Jhund, Mark C Petrie, John J V McMurray
AIMS: Guidelines for the management of chronic heart failure (CHF) cite the results of randomized controlled trials (RCTs) to support treatment recommendations. The significance of an observed treatment-effect relies on the use of a boundary P-value, most commonly P < 0.05. There is concern about relying on arbitrary threshold P-values to report results as 'statistically significant'. The 'fragility index' (FI) has been proposed as an additional measure of the robustness of trial findings...
October 14, 2016: European Heart Journal
https://www.readbyqxmd.com/read/27725999/added-clinical-use-of-trabecular-bone-score-to-bmd-for-major-osteoporotic-fracture-prediction-in-older-chinese-people-the-mr-os-and-ms-os-cohort-study-in-hong-kong
#16
Y Su, J Leung, D Hans, B Aubry-Rozier, T Kwok
: The thresholds of trabecular bone score (TBS) require validation for clinical application in older Chinese people. The lower threshold of TBS significantly improved the accuracy of prediction by bone mineral density-based osteoporosis status for major osteoporotic fracture in older Chinese men. INTRODUCTION: Trabecular bone score (TBS) is a relatively new indicator of skeletal fragility. Its clinical application warrants further investigations. Our aim was to validate and recommend practical thresholds of TBS for fracture prediction in older Chinese people...
October 11, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27722900/comparison-of-trabecular-bone-score-and-hip-structural-analysis-with-frax-%C3%A2-in-postmenopausal-women-with-type-2-diabetes-mellitus
#17
Gloria Bonaccorsi, Enrica Fila, Carmelo Messina, Elisa Maietti, Fabio Massimo Ulivieri, Renata Caudarella, Pantaleo Greco, Giuseppe Guglielmi
PURPOSE: To evaluate (a) the performance in predicting the presence of bone fractures of trabecular bone score (TBS) and hip structural analysis (HSA) in type 2 diabetic postmenopausal women compared to a control group and (b) the fracture prediction ability of TBS versus Fracture Risk Calculator (FRAX(®)) as well as whether TBS can improve the fracture prediction ability of FRAX(®) in diabetic women. METHODS: Eighty diabetic postmenopausal women were matched with 88 controls without major diseases for age and body mass index...
October 8, 2016: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/27708960/increasing-body-fat-mass-reverses-bone-loss-in-osteopenia-as-detected-by-dual-energy-x-ray-absorptiometry-scans
#18
William P Hedges, Marwan Bukhari
OBJECTIVE: Low body mass index (BMI) is a known risk factor for osteoporosis and is part of the FRAX™ 10-year fracture risk stratification tool for predicting fragility fractures. Little is known regarding the effects of changing body composition on bone mineral density (BMD). However, increasing fat mass (FM) improves BMD in young women with anorexia nervosa. This study aimed to assess whether changes in FM over time affected BMD in the general population. MATERIAL AND METHODS: Data was collected from patients who underwent dual-energy X-ray absorptiometry (DEXA) assessment between 2004 and 2011...
March 2016: European Journal of Rheumatology
https://www.readbyqxmd.com/read/27696099/utilization-of-osteoporosis-medication-after-a-fragility-fracture-among-elderly-medicare-beneficiaries
#19
Akeem A Yusuf, Thomas J Matlon, Andreas Grauer, Richard Barron, David Chandler, Yi Peng
: Osteoporosis medications are recommended for elderly patients after a fragility fracture. However, we found substantial under-treatment in the post-fracture year, especially among patients who had not previously received such medications. Improved treatment of elderly patients experiencing fragility fractures is needed. INTRODUCTION: Osteoporosis medications are recommended for elderly patients after a fragility fracture, but under-treatment is common. We determined osteoporosis medication use after fragility fractures and examined associated factors...
December 2016: Archives of Osteoporosis
https://www.readbyqxmd.com/read/27670687/peripheral-quantitative-computed-tomography-pqct-for-the-assessment-of-bone-strength-in-most-of-bone-affecting-conditions-in-developmental-age-a-review
#20
Stefano Stagi, Loredana Cavalli, Tiziana Cavalli, Maurizio de Martino, Maria Luisa Brandi
Peripheral quantitative computed tomography provides an automatical scan analysis of trabecular and cortical bone compartments, calculating not only their bone mineral density (BMD), but also bone geometrical parameters, such as marrow and cortical Cross-Sectional Area (CSA), Cortical Thickness (CoTh), both periosteal and endosteal circumference, as well as biomechanical parameters like Cross-Sectional Moment of Inertia (CSMI), a measure of bending, polar moment of inertia, indicating bone strength in torsion, and Strength Strain Index (SSI)...
September 26, 2016: Italian Journal of Pediatrics
keyword
keyword
115761
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"