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https://www.readbyqxmd.com/read/28098831/a-fast-multimodal-ectopic-beat-detection-method-applied-for-blood-pressure-estimation-based-on-pulse-wave-velocity-measurements-in-wearable-sensors
#1
Maik Pflugradt, Kai Geissdoerfer, Matthias Goernig, Reinhold Orglmeister
Automatic detection of ectopic beats has become a thoroughly researched topic, with literature providing manifold proposals typically incorporating morphological analysis of the electrocardiogram (ECG). Although being well understood, its utilization is often neglected, especially in practical monitoring situations like online evaluation of signals acquired in wearable sensors. Continuous blood pressure estimation based on pulse wave velocity considerations is a prominent example, which depends on careful fiducial point extraction and is therefore seriously affected during periods of increased occurring extrasystoles...
January 14, 2017: Sensors
https://www.readbyqxmd.com/read/28089192/commissioning-monte-carlo-algorithm-for-robotic-radiosurgery-using-cylindrical-3d-array-with-variable-density-inserts
#2
D Dechambre, V Baart, S Cucchiaro, C Ernst, N Jansen, P Berkovic, C Mievis, P Coucke, A Gulyban
INTRODUCTION: To commission the Monte Carlo (MC) algorithm based model of CyberKnife robotic stereotactic system (CK) and evaluate the feasibility of patient specific QA using the ArcCHECK cylindrical 3D-array (AC) with Multiplug inserts (MP). RESULTS: Four configurations were used for simple beam setup and two for patient QA, replacing water equivalent inserts by lung. For twelve collimators (5-60mm) in simple setup, mean (SD) differences between MC and RayTracing algorithm (RT) of the number of points failing the 3%/1mmgamma criteria were 1(1), 1(3), 1(2) and 1(2) for the four MP configurations...
January 11, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28078128/endoscopic-ultrasound-in-pancreatic-cancer-innovative-applications-beyond-the-basics
#3
REVIEW
Joseph Yoo, C Andrew Kistler, Linda Yan, Andrew Dargan, Ali A Siddiqui
Endoscopic ultrasound (EUS) has become a mainstay in assisting in the diagnosis and staging of pancreatic cancer. In addition, EUS provides a modality to treat chronic pain through celiac plexus neurolysis. Currently, there is growing data and utilization of EUS in more diverse and innovative applications aimed at providing more sophisticated diagnostic, prognostic and therapeutic options for patients with pancreatic cancer. EUS delivery of chemotherapy, viral and biological vectors and fiducial markers may eventually revolutionize the way clinicians approach the care of a patient with pancreatic cancer...
December 2016: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28072584/verification-of-respiratory-gated-radiotherapy-with-new-real-time-tumour-tracking-radiotherapy-system-using-cine-epid-images-and-a-log-file
#4
Takehiro Shiinoki, Hideki Hanazawa, Yuki Yuasa, Koya Fujimoto, Takuya Uehara, Keiko Shibuya
<u>Purposes:</u> A combined system comprising the TrueBeam linear accelerator and a new real-time tumour-tracking radiotherapy system, SyncTraX, was installed at our institution. The objectives of this study are to develop a method for the verification of respiratory-gated radiotherapy with SyncTraX using cine electronic portal image device (EPID) images and a log file and to verify this treatment in clinical cases. <u>Methods and Materials:</u> Respiratory-gated radiotherapy was performed using TrueBeam and the SyncTraX system...
January 10, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28071340/respiration-induced-intraorgan-deformation-of-the-liver
#5
Anna K Paulsson, Sue S Yom, Mekhail Anwar, Dilini Pinnaduwage, Atchar Sudhyadhom, Alexander R Gottschalk, Albert J Chang, Martina Descovich
Stereotactic body radiation therapy is a well-tolerated modality for the treatment of primary and metastatic liver lesions, and fiducials are often used as surrogates for tumor tracking during treatment. We evaluated respiratory-induced liver deformation by measuring the rigidity of the fiducial configuration during the breathing cycle. Seventeen patients, with 18 distinct treatment courses, were treated with stereotactic body radiosurgery using multiple fiducials. Liver deformation was empirically quantified by measuring the intrafiducial distances at different phases of respiration...
January 1, 2017: Technology in Cancer Research & Treatment
https://www.readbyqxmd.com/read/28069539/quantification-of-local-geometric-distortion-in-structural-magnetic-resonance-images-application-to-ultra-high-fields
#6
Jonathan C Lau, Ali R Khan, Tony Y Zeng, Keith MacDougall, Andrew G Parrent, Terry M Peters
Ultra-high field magnetic resonance imaging (MRI) provides superior visualization of brain structures compared to lower fields, but images may be prone to severe geometric inhomogeneity. We propose to quantify local geometric distortion at ultra-high fields in in vivo datasets of human subjects scanned at both ultra-high field and lower fields. By using the displacement field derived from nonlinear image registration between images of the same subject, focal areas of spatial uncertainty are quantified. Through group and subject-specific analysis, we were able to identify regions systematically affected by geometric distortion at air-tissue interfaces prone to magnetic susceptibility, where the gradient coil non-linearity occurs in the occipital and suboccipital regions, as well as with distance from image isocenter...
January 6, 2017: NeuroImage
https://www.readbyqxmd.com/read/28066679/image-guided-techniques-for-localizing-pulmonary-nodules-in-thoracoscopic-surgery
#7
REVIEW
Mong-Wei Lin, Jin-Shing Chen
Low-dose computed tomography (LDCT) screening has increased the detection rate for small pulmonary nodules with ground-glass opacity (GGO) in the peripheral lung parenchyma. Minimally invasive thoracoscopic surgery for these lung nodules is challenging for thoracic surgeons, and image-guided preoperative localization is mandatory for their successful resection. Image-guided localization methods primarily include two imaging tools: computed tomography (CT) and bronchoscopy. These different methods may use different localized materials, including hookwires, dyes, microcoils, fiducial markers, contrast media, and radiotracers...
October 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28057427/fiducial-marker-matching-versus-vertebral-body-matching-dosimetric-impact-of-patient-positioning-in-carbon-ion-radiotherapy-for-primary-hepatic-cancer
#8
Satoshi Abe, Yoshiki Kubota, Kei Shibuya, Yoshinari Koyama, Takanori Abe, Tatsuya Ohno, Takashi Nakano
PURPOSE: The aim of this study was to compare the dose-volume parameters of fiducial marker matching (MM) with vertebral body matching (VM) in patient positioning for carbon ion radiotherapy for primary hepatic cancer. MATERIALS AND METHODS: Twenty patients with primary hepatic cancer were retrospectively studied to assess changes in reproducibility of tumor position and dose distribution on two CT scans. One was for treatment planning and another was for dose confirmation, acquired the day before the first treatment day...
January 2, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28048932/th-b-204-03-tg-199-implanted-markers-for-radiation-treatment-verification
#9
Z Wang
: Implanted markers as target surrogates have been widely used for treatment verification, as they provide safe and reliable monitoring of the inter- and intra-fractional target motion. The rapid advancement of technology requires a critical review and recommendation for the usage of implanted surrogates in current field. The symposium, also reporting an update of AAPM TG 199 - Implanted Target Surrogates for Radiation Treatment Verification, will be focusing on all clinical aspects of using the implanted target surrogates for treatment verification and related issues...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048904/su-g-bra-02-development-of-a-learning-based-block-matching-algorithm-for-ultrasound-tracking-in-radiotherapy
#10
A Shepard, B Bednarz
PURPOSE: To develop an ultrasound learning-based tracking algorithm with the potential to provide real-time motion traces of anatomy-based fiducials that may aid in the effective delivery of external beam radiation. METHODS: The algorithm was developed in Matlab R2015a and consists of two main stages: reference frame selection, and localized block matching. Immediately following frame acquisition, a normalized cross-correlation (NCC) similarity metric is used to determine a reference frame most similar to the current frame from a series of training set images that were acquired during a pretreatment scan...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048861/su-g-jep1-09-evaluation-of-transperineal-ultrasound-imaging-as-a-potential-solution-for-target-tracking-during-ablative-body-radiotherapy-for-prostate-cancer
#11
M Najafi, B Han, D Cooper, S Hancock, D Hristov
PURPOSE: Prostate SABR is emerging as a clinically viable, potentially cost effective alternative to prostate IMRT but its adoption is contingent on providing solutions for accurate tracking during beam delivery. Our goal is to evaluate the performance of the Clarity Autoscan ultrasound monitoring system for inter-fractional prostate motion tracking in both phantoms and in-vivo. METHODS: In-vivo evaluation was performed under IRB protocol to allow data collection in prostate patients treated with VMAT whereby prostate was imaged through the acoustic window of the perineum...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048509/th-a-brc-03-aapm-tg218-measurement-methods-and-tolerance-levels-for-patient-specific-imrt-verification-qa
#12
M Miften
: AAPM TG-135U1 QA for Robotic Radiosurgery - Sonja Dieterich Since the publication of AAPM TG-135 in 2011, the technology of robotic radiosurgery has rapidly developed. AAPM TG-135U1 will provide recommendations on the clinical practice for using the IRIS collimator, fiducial-less real-time motion tracking, and Monte Carlo based treatment planning. In addition, it will summarize currently available literature about uncertainties. LEARNING OBJECTIVES: 1. Understand the progression of technology since the first TG publication 2...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048489/th-ab-202-10-quantifying-the-accuracy-and-precision-of-six-degree-of-freedom-motion-estimation-for-use-in-real-time-tumor-motion-monitoring-during-radiotherapy
#13
J Kim, D Nguyen, C Huang, R O'Brien, V Caillet, P Poulsen, J Booth, P Keall
PURPOSE: Kilovoltage intrafraction monitoring (KIM) scheme has been successfully used to simultaneously monitor 3D tumor motion during radiotherapy. Recently, an iterative closest point (ICP) algorithm was implemented in KIM to also measure rotations about three axes, enabling real-time tracking of tumor motion in six degrees-of-freedom (DoF). This study aims to evaluate the accuracy of the six DoF motion estimates of KIM by comparing it with the corresponding motion (i) measured by the Calypso; and (ii) derived from kV/MV triangulation...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048478/th-b-204-01-real-time-tracking-with-implanted-markers
#14
Q Xu
: Implanted markers as target surrogates have been widely used for treatment verification, as they provide safe and reliable monitoring of the inter- and intra-fractional target motion. The rapid advancement of technology requires a critical review and recommendation for the usage of implanted surrogates in current field. The symposium, also reporting an update of AAPM TG 199 - Implanted Target Surrogates for Radiation Treatment Verification, will be focusing on all clinical aspects of using the implanted target surrogates for treatment verification and related issues...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048421/su-g-tep3-06-nanoparticle-aided-external-beam-radiotherapy-leveraging-the-cerenkov-effect
#15
Z Ouyang, B Liu, S Yasmin-Karim, E Sajo, W Ngwa
PURPOSE: This study investigates the feasibility of exploiting the Cerenkov radiation (CR) present during external beam radiotherapy (EBRT) for significant therapeutic gain, using titanium dioxide nanoparticles (titania) delivered via a new design of radiotherapy biomaterials. METHODS: Recently published work has shown that CR generated by radionuclides during PET imaging could substantially enhance damage to cancer cells in the presence of 0.625 µg/g titania. We hypothesize that equal or greater damage can be achieved during EBRT...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048355/th-cd-207a-04-optimized-respiratory-gating-for-abnormal-breathers-in-pancreatic-sbrt
#16
W Campbell, M Miften, T Schefter, K Goodman, B Jones
PURPOSE: Pancreatic SBRT is uniquely challenging due to both the erratic/unstable motion of the pancreas and the close proximity of the radiosensitive small bowel. Respiratory gating can mitigate this effect, but the irregularity of motion severely affects traditional phase-based gating. The purpose of this study was to analyze real-time motion data of pancreatic tumors to optimize the efficacy and accuracy of respiratory gating, with the overall goal of enabling dose escalated pancreatic SBRT...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048350/su-f-p-30-clinical-assessment-of-auto-beam-hold-triggered-by-fiducial-localization-during-prostate-rapidarc-delivery
#17
P Atkinson, Q Chen
PURPOSE: To assess the clinical efficacy of auto beam hold during prostate RapidArc delivery, triggered by fiducial localization on kV imaging with a Varian True Beam. METHODS: Prostate patients with four gold fiducials were candidates in this study. Daily setup was accomplished by aligning to fiducials using orthogonal kV imaging. During RapidArc delivery, a kV image was automatically acquired with a momentary beam hold every 60 degrees of gantry rotation. The position of each fiducial was identified by a search algorithm and compared to a predetermined 1...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048346/su-f-t-660-evaluating-the-benefit-of-using-dual-function-fiducial-markers-for-in-situ-delivery-of-radiosenistizing-gold-nanoparticles-during-image-guided-radiotherapy
#18
S AlMansour, J Chin, E Sajo, W Ngwa
PURPOSE: Dual-function fiducials loaded with radiosensitizers, like gold nanoparticles (GNP), offer an innovative approach for ensuring geometric accuracy during image-guided radiotherapy (IGRT) and significantly increasing therapeutic efficacy due to controlled in-situ release of the radiosensitizers. This study retrospectively investigates the dosimetric benefit of using up to two such dual-function fiducial markers instead of traditional single function fiducials during IGRT. METHODS: A computational code was developed to investigate the dosimetric benefit for 10 real patient tumor volumes of up to 6...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048292/su-g-jep4-06-evaluation-of-interfractional-and-intrafractional-tumor-motion-in-stereotactic-liver-radiotherapy-based-on-four-dimensional-cone-beam-computed-tomography-using-fiducial-markers
#19
Y Shimohigashi, F Araki, R Toya, M Maruyama, Y Nakaguchi
PURPOSE: The purpose of this study was to evaluate the interfractional and intrafractional motion of liver tumors in stereotactic body radiation therapy (SBRT), based on four-dimensional cone-beam computed tomography using fiducial markers. (4D-CBCT). METHODS: Seven patients with liver tumors were treated by SBRT with abdominal compression (AC) in five fractions with image guidance based on 4D-CBCT. The 4D-CBCT studies were performed to determine the individualized internal margin for the planning simulation...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048210/su-g-jep1-10-feasibility-of-cyberknife-tracking-using-the-previously-implanted-permanent-brachytherapy-seed-cloud
#20
J Cheung, J Cunha, A Sudhyadhom, C McGuinness, M Roach, M Descovich
PURPOSE: Robotic radiosurgery is a salvage treatment option for patients with recurrent prostate cancer. We explored the feasibility of tracking the bolus of permanent prostate implants (PPI) using image recognition software optimized to track spinal anatomy. METHODS: Forty-five inert iodine seeds were implanted into a gelatin-based prostate phantom. Four superficial gold seeds were inserted to provide ground-truth alignment. A CT scan of the phantom (120 kVp, 1 mm slice thickness) was acquired and a single-energy iterative metal artifact reduction (MAR) algorithm was used to enhance the quality of the DRR used for tracking...
June 2016: Medical Physics
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