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Philadelphia University

James R McCarthy, T Sloane Guy
Mitral valve dysfunction can seriously impair patients' lives and may require valve repair or replacement. Surgery can be performed using techniques including sternotomy; right thoracotomy with or without robot assistance; and the totally endoscopic robotic technique, which requires percutaneous techniques, femoral cannulation, and endovascular aortic cross-clamping. The totally endoscopic robotic technique has been facilitated by minimally invasive surgical techniques, the evolution of endoscopic techniques, and the development of surgical robots...
October 2016: AORN Journal
Thomas M Kelley, Mohammed Kashem, He Wang, James McCarthy, Nels D Carroll, G William Moser, T Sloane Guy
BACKGROUND: This study reported on the treatment of Carpentier type IIIa and type IIIb mitral regurgitation (MR) with a large patch anterior mitral valve leaflet augmentation technique using CorMatrix (CorMatrix Cardiovascular Inc, Alpharetta, GA) extracellular matrix (ECM). METHODS: A single-site chart review was conducted on patients who underwent anterior leaflet augmentation performed with the Da Vinci surgical robot (Intuitive Surgical, Sunnyvale, CA) or through a median sternotomy...
September 9, 2016: Annals of Thoracic Surgery
Jingwen Zhang, Devon Brackbill, Sijia Yang, Joshua Becker, Natalie Herbert, Damon Centola
To identify what features of online social networks can increase physical activity, we conducted a 4-arm randomized controlled trial in 2014 in Philadelphia, PA. Students (n = 790, mean age = 25.2) at an university were randomly assigned to one of four conditions composed of either supportive or competitive relationships and either with individual or team incentives for attending exercise classes. The social comparison condition placed participants into 6-person competitive networks with individual incentives...
December 2016: Preventive Medicine Reports
(no author information available yet)
No abstract text is available yet for this article.
August 2016: Therapeutic Hypothermia and Temperature Management
Catherine Loveland-Jones, Lucas Ferrer, Scott Charles, Frederick V Ramsey, Andrea VanZandt, Jill Volgraf, Thomas Santora, Abhijit Pathak, Jay Dujon, Lars Sjoholm, Joseph Rappold, Amy Goldberg
BACKGROUND: From 2002-2011, there were over 17,000 shootings in Philadelphia. "Turning Point", Temple University Hospital's inpatient violence intervention program, takes advantage of the teachable moment that occurs after violent injury. In addition to receiving traditional social work services, Turning Point patients watch their trauma bay resuscitation video and a movie about violence, meet with a gunshot wound survivor and an outpatient case manager, and also undergo psychiatric assessment...
August 18, 2016: Journal of Trauma and Acute Care Surgery
M Alizadeh, A Intintolo, D M Middleton, C J Conklin, S H Faro, M J Mulcahey, F B Mohamed
STUDY DESIGN: Quantitative study. OBJECTIVES: To evaluate the effectiveness of pediatric spinal cord diffusion tensor tractography (DTT) generated from reduced field of view diffusion tensor imaging (DTI) data and investigate whether there are differences in these values between typically developing (TD) subjects and patients with spinal cord injury (SCI). SETTING: Temple University Hospital and Shriners Hospitals for Children-Philadelphia, USA...
August 16, 2016: Spinal Cord
Angela Toss, Juan Palazzo, Adam Berger, Frances Guiles, Jocelyn Andrel Sendecki, Nicole Simone, Rani Anne, Tiffany Avery, Rebecca Jaslow, Melissa Lazar, Theodore Tsangaris, Massimo Cristofanilli
The primary aim in the management of DCIS is the prevention of recurrence and contralateral tumor. Risk factors for DCIS recurrence and appropriate treatments are still widely debated. Adjuvant therapies after surgical resection reduce recurrences and contralateral disease, but these treatments have significant financial costs, side effects and there is a group of low-risk patients who would not gain additional benefit. The aim of our analysis was to identify clinical-pathological features and treatment modalities associated with recurrence in DCIS and microinvasive carcinoma...
October 2016: Breast: Official Journal of the European Society of Mastology
Devanshi Mehta, Sarah E Noon, Emily Schwartz, Alisha Wilkens, Emma C Bedoukian, Irene Scarano, E Bryan Crenshaw, Ian D Krantz
Hearing loss is a relatively common condition in children, occurring in approximately 2 out of every 1,000 births with approximately 50% of reported diagnoses having a primary genetic etiology. Given the prevalence and genetic component of hearing loss, coupled with a trend toward early diagnosis with the institution of universal newborn hearing screening, The Genetics of Hearing Loss Clinic was established at The Children's Hospital of Philadelphia to manage the diagnosis, testing, and genetic counseling for individuals and families...
October 2016: American Journal of Medical Genetics. Part A
Barbara Milrod, Dianne L Chambless, Robert Gallop, Fredric N Busch, Michael Schwalberg, Kevin S McCarthy, Charles Gross, Brian A Sharpless, Andrew C Leon, Jacques P Barber
OBJECTIVE: To compare cognitive-behavioral therapy (CBT), panic-focused psychodynamic psychotherapy (PFPP), and applied relaxation training (ART) for primary DSM-IV panic disorder with and without agoraphobia in a 2-site randomized controlled trial. METHOD: 201 patients were stratified for site and DSM-IV agoraphobia and depression and were randomized to CBT, PFPP, or ART (19-24 sessions) over 12 weeks in a 2:2:1 ratio at Weill Cornell Medical College (New York, New York) and University of Pennsylvania ("Penn"; Philadelphia, Pennsylvania)...
July 2016: Journal of Clinical Psychiatry
A Kaifie, S Isfort, N Gattermann, W Hollburg, M Klausmann, D Wolf, C Maintz, M Hänel, E Goekkurt, J R Göthert, U Platzbecker, T Geer, S Parmentier, E Jost, H Serve, G Ehninger, W E Berdel, T H Brümmendorf, Steffen Koschmieder
Philadelphia-negative myeloproliferative neoplasms (MPN) comprise a heterogeneous group of chronic hematological malignancies with significant variations in clinical characteristics. Due to the long survival and the feasibility of oral or subcutaneous therapy, these patients are frequently treated outside of larger academic centers. This analysis was performed to elucidate differences in MPN patients in three different health care settings: university hospitals (UH), community hospitals (CH), and office-based physicians (OBP)...
September 2016: Annals of Hematology
Robert J Karp, Bobby Gearing
ACKNOWLEDGEMENTS: Laura Dattner, John Krai and Linda Oppenheim provided assistance in obtaining archival material and manuscript review. Edwin Rosenthal's decedents, Robert, Eleanore Jane and Edwin Rosenthal II, provided information about their distinguished grandfather's life and commitments. Linda Oppenheim, Michael Angelo, Jessica Lydon, and Sofie Serada, archivists at Princeton University, Thomas Jefferson University, Temple University, and the College of Physicians of Philadelphia provided access to material on Edwin Rosenthal and medical care in Philadelphia at the turn of the 20th century...
February 2015: Journal of the National Medical Association
Nathan J Pauly, Jeffery C Talbert, Joshua Brown
BACKGROUND: Administrative claims data are used for a wide variety of research and quality assurance purposes; however, they are prone to medication exposure misclassification if medications are purchased without using an insurance benefit. Low-cost generic drug programs (LCGPs) offered at major chain pharmacies are a relatively new and sparsely investigated source of exposure misclassification. LCGP medications are often purchased out of pocket; thus, a pharmacy claim may never be submitted, and the exposure may go unobserved in claims data...
June 2016: Journal of Managed Care & Specialty Pharmacy
Adisak Tantiworawit, Supanat Kongjarern, Ekarat Rattarittamrong, Suree Lekawanvijit, Kanokkan Bumroongkit, Nonglak Boonma, Thanawat Rattanathammethee, Sasinee Hantrakool, Chatree Chai-Adisaksopha, Lalita Norasetthada
BACKGROUND: A diagnosis of chronic myeloid leukemia (CML) is made on discovery of the presence of a Philadelphia (Ph) chromosome. The success of the treatment of this form of leukemia with tyrosine kinase inhibitor (TKI) is monitored by reduction of the Ph chromosome. OBJECTIVE: To compare the role of conventional cytogenetic (CC) methods with a real time quantitative polymerase chain reaction (RQ-PCR) and fluorescence in situ hybridization (FISH) for diagnosis and treatment monitoring of CML patients...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
J Wang, Yanli Zhang, J Zhou, Y L Zu, Z Li, Y P Song
OBJECTIVE: To observe the clinical features, characteristics and outcomes of chromosomal abnormalities in Philadelphia negative cells (Ph(-)CA) of chronic myeloid leukemia (CML) patients treated with tyrosine kinase inhibitor (TKI), and provide the evidence for clinical treatment. METHODS: We collected and analyzed the clinical and laboratory data of 8 CML patients treated in the affiliated Tumor Hospital of Zhengzhou University from September 2011 to July 2015 and Ph(-)CA occurred after TKI therapy...
May 14, 2016: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
Catherine Jones
This chapter explores the place of Scottish medicine in the autobiographical writing of the Philadelphia physician and signer of the American Declaration of Independence, Benjamin Rush, who studied at the University of Edinburgh from 1766 to 1768. It focuses on Rush's 'Scottish journal' (his account of his period of study in Edinburgh), his protracted feud from 1797 over his treatment of yellow fever with the English journalist, politician and agriculturalist William Cobbett, and his account in 'Travels through Life' of that feud and of the influence of Cullen on his medical theory and practice...
2014: Clio Medica: Acta Academiae Internationalis Historiae Medicinae
Ahmed M Soliman, Machaon Bonafede, Amanda M Farr, Jane Castelli-Haley, Craig Winkel
BACKGROUND: Endometriosis affects over 10 million women in the United States. Depot leuprolide acetate (LA), a gonadotropin-releasing hormone agonist, has been used extensively for the treatment of women with endometriosis but is associated with hypoestrogenic symptoms and bone mineral density loss. The concomitant use of add-back therapies, specifically norethindrone acetate (NETA), can alleviate these adverse effects. OBJECTIVE: To compare adherence to and persistence with LA treatment and time to endometriosis-related surgery among women treated with NETA and women treated with LA plus other add-back therapies or LA only...
May 2016: Journal of Managed Care & Specialty Pharmacy
Konrad Sarosiek, Ankit V Gandhi, Shivam Saxena, Christopher Y Kang, Galina I Chipitsyna, Charles J Yeo, Hwyda A Arafat
According to the epidemiological studies, about 4.4% of American general elderly population has a pronounced hypothyroidism and relies on thyroid hormone supplements daily. The prevalence of hypothyroidism in our patients with pancreatic cancer was much higher, 14.1%. A retrospective analysis was performed on patients who underwent pancreaticoduodenectomy (Whipple procedure) or distal pancreatectomy and splenectomy (DPS) at Thomas Jefferson University Hospital, Philadelphia, from 2005 to 2012. The diagnosis of hypothyroidism was correlated with clinicopathologic parameters including tumor stage, grade, and survival...
2016: Journal of Thyroid Research
Eric W Schrimshaw, Nadav Antebi-Gruszka, Martin J Downing
The last decade has seen a dramatic increase in the availability of sexually explicit media (SEM) on the Internet. Men who have sex with men (MSM) report near universal use of SEM. However, this widespread use of SEM among MSM may contribute to more condomless anal sex. To examine the association of viewing SEM on the Internet and the number of condomless anal sex encounters among MSM, in 2012, an online survey was conducted of 265 MSM from New York, Philadelphia, Baltimore, or Washington D.C. who reported viewing SEM online in the past 3 months...
2016: PloS One
Irum Khan, Ardaman Shergill, Santosh L Saraf, Yi-Fan Chen, Pritesh R Patel, John G Quigley, David Peace, Victor R Gordeuk, Ronald Hoffman, Damiano Rondelli
BACKGROUND: The Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs) are characterized by an increased risk of thrombotic and hemorrhagic complications. Large retrospective studies have demonstrated racial disparities in MPN outcomes and attributed this to differences in access to health care. Utilizing a single institution experience, we report outcomes in patients with polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis in relation to ethno-racial background...
June 2016: Clinical Lymphoma, Myeloma & Leukemia
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