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https://www.readbyqxmd.com/read/29189341/normative-data-set-of-sway-balance-mobile-assessment-in-pediatric-athletes
#1
Stevi L Anderson, Dustin Gatens, Colette Glatts, Stephen A Russo
OBJECTIVE: To examine and describe normative values for an objective, mobile measure of postural stability commonly used in concussion assessments, SWAY Balance (SWAY Medical, Tulsa, Oklahoma). DESIGN: Retrospective analysis of baseline balance assessments in a healthy pediatric population. SETTING: Baseline assessments completed by certified athletic trainers at an outpatient concussion center or sports medicine offices in Philadelphia, PA and surrounding suburban Pennsylvania and New Jersey or during an athletic trainer's baseline assessment of collegiate athletes at a National Collegiate Athletic Association (NCAA) Division-II University in Fort Lauderdale, FL...
November 16, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29047122/the-presence-of-philadelphia-chromosome-does-not-confer-poor-prognosis-in-adult-pre-b-acute-lymphoblastic-leukaemia-in-the-tyrosine-kinase-inhibitor-era-a-surveillance-epidemiology-and-end-results-database-analysis
#2
Igwe J Igwe, Dongyun Yang, Akil Merchant, Noah Merin, George Yaghmour, Kevin Kelly, Giridharan Ramsingh
The BCR-ABL1 fusion gene is caused by a translocation between chromosomes 9 and 22, resulting in an abnormal chromosome 22 (Philadelphia chromosome; Ph). Prior to the introduction of tyrosine kinase inhibitors (TKI), the presence of BCR-ABL1 conferred a poor prognosis in patients with acute lymphoblastic leukaemia (ALL). We compared the survival of Ph+ and Ph-ALL during the period when TKIs were universally available in the US for Ph+ALL, using a Surveillance, Epidemiology, and End Results (SEER) Database analysis...
October 18, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/29039548/-corrigendum-farnesoid-x-receptor-deletion-improves-cardiac-function-structure-and-remodeling-following-myocardial-infarction-in-mice
#3
Jianshu Gao, Xiaoqiang Liu, Bingjian Wang, Haiyan Xu, Qiang Xia, Tianfei Lu, Fang Wang
Following the publication of this article, an interested reader drew to our attention that we had incorrectly reported (in the Materials and methods section, 'Western blot analysis', on p. 674) that the anti-farnesoid X receptor (FXR) antibody of Cell Signalling Technology, Inc., cat. no. #12295, had been used in this study to probe for FXR. In fact, the antibodies used in the above-mentioned study were a gift from the group of Dr Xin-Liang Ma at Thomas Jefferson University (Philadelphia, PA, USA), as referenced in the following article: [Pul J, Yuan A, Shan P, Gao E, Wang X, Wang Y, Lau WB, Koch W, Xin-Ma XL and He B: Cardiomyocyte-expressed farnesoid-X-receptor is a novel apoptosis mediator and contributes to myocardial ischaemia/reperfusion injury...
December 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29021977/the-consensus-from-the-mycobacterium-avium-ssp-paratuberculosis-map-conference-2017
#4
J Todd Kuenstner, Saleh Naser, William Chamberlin, Thomas Borody, David Y Graham, Adrienne McNees, John Hermon-Taylor, Amy Hermon-Taylor, C Thomas Dow, Walter Thayer, James Biesecker, Michael T Collins, Leonardo A Sechi, Shoor Vir Singh, Peilin Zhang, Ira Shafran, Stuart Weg, Grzegorz Telega, Robert Rothstein, Harry Oken, Stephen Schimpff, Horacio Bach, Tim Bull, Irene Grant, Jay Ellingson, Heinrich Dahmen, Judith Lipton, Saurabh Gupta, Kundan Chaubey, Manju Singh, Prabhat Agarwal, Ashok Kumar, Jyoti Misri, Jagdip Sohal, Kuldeep Dhama, Zahra Hemati, William Davis, Michael Hier, John Aitken, Ellen Pierce, Nicole Parrish, Neil Goldberg, Maher Kali, Sachin Bendre, Gaurav Agrawal, Robert Baldassano, Preston Linn, Raymond W Sweeney, Marie Fecteau, Casey Hofstaedter, Raghava Potula, Olga Timofeeva, Steven Geier, Kuruvilla John, Najah Zayanni, Hoda M Malaty, Christopher Kahlenborn, Amanda Kravitz, Adriano Bulfon, George Daskalopoulos, Hazel Mitchell, Brett Neilan, Verlaine Timms, Davide Cossu, Giuseppe Mameli, Paul Angermeier, Tomislav Jelic, Ralph Goethe, Ramon A Juste, Lauren Kuenstner
On March 24 and 25, 2017 researchers and clinicians from around the world met at Temple University in Philadelphia to discuss the current knowledge of Mycobacterium avium ssp. paratuberculosis (MAP) and its relationship to human disease. The conference was held because of shared concern that MAP is a zoonotic bacterium that poses a threat not only to animal health but also human health. In order to further study this problem, the conferees discussed ways to improve MAP diagnostic tests and discussed potential future anti-MAP clinical trials...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/29016180/albert-pepitone-1925-2016
#5
Florence L Denmark
Presents an obituary for Albert Pepitone, who died on March 17, 2016, in Philadelphia at the age of 91. Pepitone was a renowned social psychologist and professor emeritus at the University of Pennsylvania. His expertise in social psychology opened up areas that significantly broadened its scope, in particular calling attention to cultural issues. wrote extensively, including many scholarly articles and contributions to published volumes. Pepitone's research was largely experimental, testing hypotheses in cognitive, motivational, interpersonal, and group processes...
October 2017: American Psychologist
https://www.readbyqxmd.com/read/28987078/brief-report-stability-and-chemical-characteristics-of-injectable-ascorbic-acid-for-patients-with-cancer
#6
Daniel A Monti, Anthony J Bazzan, George Zabrecky, Andrew B Newberg
Context • Intravenous ascorbic acid (IVAA) has been used extensively as part of the management plan for cancer patients in various medical clinics throughout the United States. The current research team has evaluated its effectiveness in patients with cancer as part of an ongoing research program. However, no data are available that support the chemical stability of intravenously injectable ascorbic acid (AA) to ensure its safety and efficacy in that patient population. Its clinical use as well as its use in research conducted in US Food and Drug Administration-approved clinical trials require validation of its stability...
October 2, 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/28935387/attitudes-and-beliefs-pertaining-to-sexual-and-reproductive-health-among-unmarried-female-bhutanese-refugee-youth-in-philadelphia
#7
Cherie Priya Dhar, Dilu Kaflay, Nadia Dowshen, Victoria A Miller, Kenneth R Ginsburg, Frances K Barg, Katherine Yun
PURPOSE: We explored attitudes and beliefs pertaining to sexual and reproductive health (SRH) among unmarried, female, resettled Bhutanese refugees 16-20 years. METHODS: Fourteen interviews were analyzed using the constant comparison method, and major themes were identified. RESULTS: SRH was stigmatized for unmarried youth, making seeking information about SRH or accessing family planning difficult. There were many misconceptions about access to SRH...
September 18, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28905095/growing-canopy-on-a-college-campus-understanding-urban-forest-change-through-archival-records-and-aerial-photography
#8
Lara A Roman, Jason P Fristensky, Theodore S Eisenman, Eric J Greenfield, Robert E Lundgren, Chloe E Cerwinka, David A Hewitt, Caitlin C Welsh
Many municipalities are setting ambitious tree canopy cover goals to increase the extent of their urban forests. A historical perspective on urban forest development can help cities strategize how to establish and achieve appropriate tree cover targets. To understand how long-term urban forest change occurs, we examined the history of trees on an urban college campus: the University of Pennsylvania in Philadelphia, PA. Using a mixed methods approach, including qualitative assessments of archival records (1870-2017), complemented by quantitative analysis of tree cover from aerial imagery (1970-2012), our analysis revealed drastic canopy cover increase in the late 20th and early 21st centuries along with the principle mechanisms of that change...
December 2017: Environmental Management
https://www.readbyqxmd.com/read/28864545/first-person-luca-sardo
#9
(no author information available yet)
First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Luca Sardo is co-first author on 'Real-time visualization of chromatin modification in isolated nuclei', published in Journal of Cell Science. Dr Sardo is a Postdoctoral Fellow at the Department of Biological Sciences, University of the Sciences in Philadelphia, investigating the mechanisms of HIV neuropathogenesis and latency...
September 1, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/28859185/salvage-chemoimmunotherapy-with-inotuzumab-ozogamicin-combined-with-mini-hyper-cvd-for-patients-with-relapsed-or-refractory-philadelphia-chromosome-negative-acute-lymphoblastic-leukemia-a-phase-2-clinical-trial
#10
Elias Jabbour, Farhad Ravandi, Partow Kebriaei, Xuelin Huang, Nicholas J Short, Deborah Thomas, Koji Sasaki, Michael Rytting, Nitin Jain, Marina Konopleva, Guillermo Garcia-Manero, Richard Champlin, David Marin, Tapan Kadia, Jorge Cortes, Zeev Estrov, Koichi Takahashi, Yogin Patel, Maria R Khouri, Jovitta Jacob, Rebecca Garris, Susan O'Brien, Hagop Kantarjian
Importance: The outcome of patients with relapsed or refractory (R/R) acute lymphoblastic leukemia (ALL) is poor. Inotuzumab ozogamicin, a CD22 monoclonal antibody bound to calicheamicin, has single-agent activity in R/R ALL. Objective: To evaluate the efficacy and safety of inotuzumab ozogamicin plus low-intensity chemotherapy in patients with R/R ALL. Design, Setting, and Participants: A single-arm, phase 2 study of adults with R/R B-cell ALL conducted at The University of Texas MD Anderson Cancer Center, Houston...
August 31, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28801082/-how-to-videos-improve-residents-performance-of-essential-perioperative-electronic-medical-records-and-clinical-tasks
#11
Veronica Zoghbi, Robert C Caskey, Kristoffel R Dumon, Jacqueline M Soegaard Ballester, Ari D Brooks, Jon B Morris, Daniel T Dempsey
OBJECTIVE: The ability to use electronic medical records (EMR) is an essential skill for surgical residents. However, frustration and anxiety surrounding EMR tasks may detract from clinical performance. We created a series of brief, 1-3 minutes "how to" videos demonstrating 7 key perioperative EMR tasks: booking OR cases, placing preprocedure orders, ordering negative-pressure wound dressing supplies, updating day-of-surgery history and physical notes, writing brief operative notes, discharging patients from the postanesthesia care unit, and checking vital signs...
August 8, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28797266/does-growing-up-with-a-physician-influence-the-ethics-of-medical-students-relationships-with-the-pharmaceutical-industry-the-cases-of-the-us-and-poland
#12
Marta Makowska
BACKGROUND: Medical schools have a major impact on future doctors' ethics and their attitudes towards cooperation with the pharmaceutical industry. From childhood, medical students who are related to a physician are exposed to the characteristics of a medical career and learn its professional ethics not only in school but also in the family setting. The present paper sought to answer the research question: 'How does growing up with a physician influence medical students' perceptions of conflicts of interest in their relationships with industry?' METHODS: An anonymous questionnaire was completed by 451 medical students from four Philadelphia medical schools and 554 medical students from Warsaw Medical University during 2013...
August 10, 2017: BMC Medical Ethics
https://www.readbyqxmd.com/read/28627929/design-of-the-hptn-065-tlc-plus-study-a-study-to-evaluate-the-feasibility-of-an-enhanced-test-link-to-care-plus-treat-approach-for-hiv-prevention-in-the-united-states
#13
Theresa Gamble, Bernard Branson, Deborah Donnell, H Irene Hall, Georgette King, Blayne Cutler, Shannon Hader, David Burns, Jason Leider, Angela Fulwood Wood, Kevin G Volpp, Kate Buchacz, Wafaa M El-Sadr
Background/Aims HIV continues to be a major public health threat in the United States, and mathematical modeling has demonstrated that the universal effective use of antiretroviral therapy among all HIV-positive individuals (i.e. the "test and treat" approach) has the potential to control HIV. However, to accomplish this, all the steps that define the HIV care continuum must be achieved at high levels, including HIV testing and diagnosis, linkage to and retention in clinical care, antiretroviral medication initiation, and adherence to achieve and maintain viral suppression...
August 2017: Clinical Trials: Journal of the Society for Clinical Trials
https://www.readbyqxmd.com/read/28604431/characteristics-of-black-men-who-have-sex-with-men-in-baltimore-philadelphia-and-washington-d-c-geographic-diversity-in-socio-demographics-and-hiv-transmission-risk
#14
MULTICENTER STUDY
Danielle German, Kathleen Brady, Irene Kuo, Jenevieve Opoku, Colin Flynn, Rudy Patrick, Ju Nyeong Park, Joella Adams, Makeda Carroll, Ron Simmons, Carlton R Smith, Wendy W Davis
BACKGROUND: Baltimore, Philadelphia, and Washington, DC are geographically proximate cities with high HIV prevalence, including among black men who have sex with men (BMSM). Using data collected among BMSM in CDC's National HIV Behavioral Surveillance project, we compared socio-demographic characteristics, HIV risk behaviors, and service utilization to explore similarities and differences that could inform local and regional HIV intervention approaches. METHODS: BMSM were recruited through venue time location sampling, June-December, 2011...
July 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28582852/human-anti-lipopolysaccharid-lps-antibodies-against-legionella-with-high-species-specificity
#15
Philipp Kuhn, Stefanie Thiem, Michael Steinert, Duncan Purvis, Veronika Lugmayr, Ulrich Treutlein, Lutz Plobner, Robert-Matthias Leiser, Michael Hust, Stefan Dübel
Legionella are Gram-negative bacteria that are ubiquitously present in natural and man-made water reservoirs. When humans inhale aerosolized water contaminated with Legionella, alveolar macrophages can be infected, which may lead to a life-threatening pneumonia called Legionnaires' disease. Due to the universal distribution of Legionella in water and their potential threat to human health, the Legionella concentration in water for human use must be strictly monitored, which is difficult since the standard detection still relies on lengthy cultivation and analysis of bacterial morphology...
July 19, 2017: Human Antibodies
https://www.readbyqxmd.com/read/28547782/due-to-potential-concerns-of-bias-and-conflicts-of-interest-regulatory-bodies-should-not-do-evaluation-methodology-research-related-to-their-regulatory-missions
#16
Dev P Chakraborty, Robert M Nishikawa, Colin G Orton
No abstract text is available yet for this article.
May 26, 2017: Medical Physics
https://www.readbyqxmd.com/read/28532255/outpatient-versus-inpatient-management-for-superimposed-preeclampsia-without-severe-features-a-retrospective-multicenter-study
#17
Corina N Schoen, Sindy C Moreno, Gabriele Saccone, Nora M Graham, Lauren C Hand, Giuseppe M Maruotti, Pasquale Martinelli, Vincenzo Berghella, Amanda Roman
PURPOSE: To determine if women with preterm superimposed preeclampsia without severe features can be successfully and safely triaged to outpatient management. MATERIALS AND METHODS: This was a multicenter, retrospective, cohort study of singleton pregnancies with superimposed preeclampsia without severe features diagnosed before 37 weeks managed outpatient versus inpatient at Thomas Jefferson University (Philadelphia, PA) and at University of Naples (Naples, Italy) from January 2008 to July 2015...
June 8, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28526330/going-social-success-in-online-recruitment-of-men-who-have-sex-with-men-for-prevention-hiv-vaccine-research
#18
Lindsey Buckingham, Julie Becher, Chelsea D Voytek, Danielle Fiore, Debora Dunbar, Annet Davis-Vogel, David S Metzger, Ian Frank
OBJECTIVE: To compare the use of four different social media sites to recruit men who have sex with men (MSM) and transgender women to a phase 2b HIV prevention vaccine trial, HVTN 505. DESIGN: Retrospective, observational study. METHODS: The University of Pennsylvania HIV Vaccine Trials Unit (Penn HVTU) employed street outreach and online recruitment methods to recruit participants for HVTN 505 using a combination of national recruitment images/messages with Philadelphia-specific language and imagery...
June 14, 2017: Vaccine
https://www.readbyqxmd.com/read/28514311/trends-in-esophageal-and-esophagogastric-junction-cancer-research-from-2007-to-2016-a-bibliometric-analysis
#19
REVIEW
Yan Miao, Ran Liu, Yuepu Pu, Lihong Yin
BACKGROUND: This study aimed to analyze the scientific outputs of esophageal and esophagogastric junction (EGJ) cancer and construct a model to quantitatively and qualitatively evaluate pertinent publications from the past decade. METHODS: Publications from 2007 to 2016 were retrieved from the Web of Science Core Collection database. Microsoft Excel 2016 (Redmond, WA) and the CiteSpace (Drexel University, Philadelphia, PA) software were used to analyze publication outcomes, journals, countries, institutions, authors, research areas, and research frontiers...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28443274/the-guatemala-penn-partners-an-innovative-inter-institutional-model-for-scientific-capacity-building-healthcare-education-and-public-health
#20
Maria Alejandra Paniagua-Avila, Elizabeth Messenger, Caroline A Nelson, Erwin Calgua, Frances K Barg, Kent W Bream, Charlene Compher, Anthony J Dean, Sergio Martinez-Siekavizza, Victor Puac-Polanco, Therese S Richmond, Rudolf R Roth, Charles C Branas
Population health outcomes are directly related to robust public health programs, access to basic health services, and a well-trained health-care workforce. Effective health services need to systematically identify solutions, scientifically test these solutions, and share generated knowledge. The World Health Organization (WHO)'s Global Healthcare Workforce Alliance states that the capacity to perform research is an essential factor for well-functioning public health systems. Low- and middle-income countries have greater health-care worker shortages and lower research capacity than higher-income countries...
2017: Frontiers in Public Health
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