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Cardiovascular tomography

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https://www.readbyqxmd.com/read/29447342/diagnosing-coronary-artery-disease-after-a-positive-coronary-computed-tomography-angiography-the-dan-nicad-open-label-parallel-head-to-head-randomized-controlled-diagnostic-accuracy-trial-of-cardiovascular-magnetic-resonance-and-myocardial-perfusion-scintigraphy
#1
L Nissen, S Winther, J Westra, J A Ejlersen, C Isaksen, A Rossi, N R Holm, G Urbonaviciene, L C Gormsen, L H Madsen, E H Christiansen, M Maeng, L L Knudsen, L Frost, L Brix, H E Bøtker, S E Petersen, M Bøttcher
Aims: Perfusion scans after coronary computed tomography angiography (CCTA) in patients with suspected coronary artery disease (CAD) may reduce unnecessary invasive coronary angiographies (ICAs). However, the diagnostic accuracy of perfusion scans after primary CCTA is unknown. The aim of this study was to determine the diagnostic accuracy of cardiac magnetic resonance (CMR) and myocardial perfusion scintigraphy (MPS) against ICA with fractional flow reserve (FFR) in patients suspected of CAD by CCTA...
February 13, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29444926/high-sensitivity-cardiac-troponin-i-and-the-diagnosis-of-coronary-artery-disease-in-patients-with-suspected-angina-pectoris
#2
Philip D Adamson, Amanda Hunter, Debbie M Madsen, Anoop S V Shah, David A McAllister, Tania A Pawade, Michelle C Williams, Colin Berry, Nicholas A Boon, Marcus Flather, John Forbes, Scott McLean, Giles Roditi, Adam D Timmis, Edwin J R van Beek, Marc R Dweck, Hans Mickley, Nicholas L Mills, David E Newby
BACKGROUND: We determined whether high-sensitivity cardiac troponin I can improve the estimation of the pretest probability for obstructive coronary artery disease (CAD) in patients with suspected stable angina. METHODS AND RESULTS: In a prespecified substudy of the SCOT-HEART trial (Scottish Computed Tomography of the Heart), plasma cardiac troponin was measured using a high-sensitivity single-molecule counting assay in 943 adults with suspected stable angina who had undergone coronary computed tomographic angiography...
February 2018: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/29444586/sex-differences-in-pericardial-adipose-tissue-assessed-by-pet-ct-and-association-with-cardiometabolic-risk
#3
Corey M Gill, Debora C Azevedo, Adriana L Oliveira, Edgar L Martinez-Salazar, Martin Torriani, Miriam A Bredella
Background Recent studies suggest that pericardial adipose tissue (PAT) is associated with whole body adiposity and insulin resistance. Moreover, the incidence of cardiovascular disease (CVD) differs between men and women. Although CVD is more prevalent in men, women suffering from CVD have a higher mortality compared to men. Differences in PAT may account for some of the observed sex differences in manifestations of CVD. Purpose To assess pericardial adipose tissue (PAT) as a biomarker for cardiometabolic risk and to assess potential sex differences...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29439144/coronary-computed-tomography-angiography-detection-of-short-and-long-term-outcomes-after-heart-valve-surgery-with-high-risk-cardiovascular-patients
#4
Zhi Zhu, Shuofeng Li
Coronary computed tomography angiography (CCTA) is a promising alternative technique to detect significant coronary artery lesions in high-risk cardiovascular patients with left ventricular dysfunction (left ventricular ejection fractions < 40%) referred for elective valve surgery, while little research about the use of CCTA to detect the outcomes of heart valve surgery was performed. Forty-six consecutive high-risk cardiovascular patients with the New York Heart Association (NYHA) classification were retrospectively studied...
February 8, 2018: Bioscience Reports
https://www.readbyqxmd.com/read/29438436/assessment-of-coronary-vascular-function-with-cardiac-pet-in-relation-to-serum-uric-acid
#5
Seoyoung C Kim, Nishant R Shah, James R Rogers, Courtney F Bibbo, Marcelo F Di Carli, Daniel H Solomon
BACKGROUND: Elevated serum uric acid (SUA) levels have been independently associated with cardiovascular disease. Stress myocardial perfusion positron emission tomography (PET) allows for measurement of absolute myocardial blood flow (MBF) and quantification of global left ventricular coronary flow reserve (CFR). A CFR <2.0 is considered impaired coronary vascular function, and it is associated with increased cardiovascular risk. We evaluated the relationship between SUA and PET-measured markers of coronary vascular function...
2018: PloS One
https://www.readbyqxmd.com/read/29438137/visualization-of-myocardial-infarction-in-postmortem-multiphase-computed-tomography-angiography-a-feasibility-study
#6
Sara Sabatasso, Jessica Vanhaebost, Francesco Doenz, Cristian Palmiere, Katarzyna Michaud, Fabrice Dedouit, Silke Grabherr
Recent studies have indicated that multiphase postmortem computed tomography angiography (MPMCTA) allows detection of a pathological enhancement of the myocardium in regions that correlate with the localization of the infarction at histology. The aim of this study was to verify this hypothesis by examining MPMCTA images in cases of myocardial infarction. Therefore, we investigated 10 autopsy cases where death was attributed to myocardial infarction or which showed cardiovascular pathology. As a control group, we selected 10 cases of non-natural (namely, not cardiac) death...
February 12, 2018: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/29434740/a-pilot-study-of-a-cardiovascular-virtual-endoscopy-system-based-on-multi-detector-computed-tomography-in-diagnosing-tetralogy-of-fallot-in-pediatric-patients
#7
Li-Ping Yao, Li Zhang, Ju Mei, Fang-Bao Ding, Hui-Ming Li, Ming Ding, Xin Yang, Xiao-Ming Li, Kun Sun
The present study aimed to investigate the capabilities of the cardiovascular virtual endoscopy (VE) system in diagnosing tetralogy of Fallot (TOF) and performing measurements. A total of 37 patients underwent two-dimensional echocardiography (2-DE) and multi-detector computed tomography (MDCT) examinations. The obtained MDCT images were applied to a cardiovascular VE system. Diagnostic time by VE was first studied and compared with MDCT. Subsequently, with surgical findings as the ground truth, the capabilities of VE, 2-DE and MDCT in diagnosing TOF and its complications were investigated...
February 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29432063/approach-to-pulmonary-hypertension-from-ct-to-clinical-diagnosis
#8
Felipe Aluja Jaramillo, Fernando R Gutierrez, Federico G Díaz Telli, Sebastian Yevenes Aravena, Cylen Javidan-Nejad, Sanjeev Bhalla
Pulmonary hypertension (PH) is a condition characterized by increased pressure in the pulmonary circulation. It may be idiopathic or arise in the setting of other clinical conditions. Patients with PH tend to present with nonspecific cardiovascular or respiratory symptoms. The clinical classification of PH was recently revised at the World Health Organization symposium in Nice, France, in 2013. That consensus statement provided an updated classification based on the shared hemodynamic characteristics and management of the different categories of PH...
February 12, 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29430434/spontaneous-disappearance-of-a-pericardial-cyst-case-report-and-literature-review
#9
Angelo Pio Moffa, Luca Pio Stoppino, Domenico Loizzi, Paola Milillo
Pericardial cysts are rare benign anomalies generally discovered as incidental findings on radiographic images. Rarely, pericardial cysts cause symptoms and may lead to complications. A 56-year-old woman presented to the emergency department for mild chest pain. A cardiovascular and respiratory examination revealed no abnormalities, while a chest X-ray and subsequent thoracic computed tomography (CT) showed a pericardial cyst. The patient refused both percutaneous treatment and thoracic surgery. Three years later, a thoracic CT scan showed that the pericardial cyst had disappeared...
February 2018: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29430423/mid-term-results-of-minimally-invasive-direct-coronary-artery-bypass-grafting
#10
Dong Hyun Seo, Jun Sung Kim, Kay-Hyun Park, Cheong Lim, Su Ryeun Chung, Dong Jung Kim
Background: Minimally invasive direct coronary artery bypass grafting (MIDCAB) has the advantage of allowing arterial grafting on the left anterior descending artery without a sternotomy incision. We present our single-center clinical experience of 66 consecutive patients. Methods: All patients underwent MIDCAB through a left anterior small thoracotomy between August 2007 and July 2015. Preoperative, intraoperative, postoperative and follow-up data-including major adverse cardiovascular and cerebrovascular events (MACCE), graft patency, and the need for re-intervention-were collected...
February 2018: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29428714/%C3%AE-amyloid-deposition-is-associated-with-gait-variability-in-usual-aging
#11
Qu Tian, Woei-Nan Bair, Susan M Resnick, Murat Bilgel, Dean F Wong, Stephanie A Studenski
BACKGROUND: Higher amyloid burden predicts gait slowing in aging. Whether and which gait characteristics are associated with amyloid burden is less clear. Gait variability may be more sensitive to amyloid burden than mean gait characteristics. METHODS: In the Baltimore Longitudinal Study of Aging, 99 older participants without neurological disease had concurrent amyloid imaging and assessment of gait characteristics. β-amyloid burden was measured using 11C-Pittsburgh compound B (PiB) positron emission tomography...
February 6, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29426687/coronary-manifestations-of-kawasaki-disease-in-computed-tomography-coronary-angiography
#12
Yong Geng Goh, Ching Ching Ong, Grace Tan, Chong Ri Liang, Sanah Merchant Soomar, Chee Wen Terence Lim, Swee Chye Quek, Li San Lynette Teo
Coronary arteritis in Kawasaki disease can lead to serious complications such myocardial infarction and sudden death. The identification of coronary manifestations with a method that is minimally invasive and of low radiation exposure is therefore important in paediatric patients with Kawasaki disease. Coronary CT angiography can be an attractive alternative to invasive coronary angiography. This paper describes imaging techniques for coronary CT angiography in pediatric patients and demonstrates the spectrum of cardiovascular manifestations in patients with Kawasaki disease...
December 11, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/29424731/efficacy-of-cardiac-shock-wave-therapy-in-patients-with-stable-angina-the-design-of-randomized-triple-blind-sham-procedure-controlled-study
#13
Evgeny Shkolnik, Greta Burneikaite, Jelena Celutkiene, Mikhail Scherbak, Gitana Zuoziene, Birute Petrauskiene, Ekaterina Trush, Aleksandras Laucevicius, Yury Vasyuk
OBJECTIVE: Despite revascularization and optimal medical treatment (OMT), patients with angina often have a reduced quality of life due to inadequate relief from symptoms. Recent studies have shown that the application of shock waves may reduce angina symptoms and improve quality of life, exercise capacity, and myocardial perfusion due to the stimulation of angiogenesis. However, there is limited evidence due to small, single-arm, single-center studies of low to moderate quality. The purpose of this study is to evaluate the impact of cardiac shock wave therapy (CSWT) on exercise tolerance and angina symptoms in patients with coronary artery disease and objective evidence of myocardial ischemia who cannot undergo traditional revascularization and experience angina despite OMT in comparison to sham procedure...
February 2018: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/29422416/incidence-and-predictors-of-lesion-specific-ischemia-by-ffrct-learnings-from-the-international-advance-registry
#14
Hironori Kitabata, Jonathon Leipsic, Manesh R Patel, Koen Nieman, Bernard De Bruyne, Campbell Rogers, Gianluca Pontone, Bjarne L Nørgaard, Jeroen J Bax, Gilbert Raff, Kavitha M Chinnaiyan, Mark Rabbat, Niels Peter Rønnow Sand, Philipp Blanke, Timothy A Fairbairn, Hitoshi Matsuo, Tetsuya Amano, Tomohiro Kawasaki, Yoshihiro Morino, Takashi Akasaka
BACKGROUND: To date, the clinical utility of coronary computed tomography angiography (CTA)-derived fractional flow reserve (FFRCT) has been limited to trials and single center experiences. We herein report the incidence of abnormal FFRCT (≤0.80) and the relationship of lesion-specific ischemia to subject demographics, symptoms, and degree of stenosis in the multicenter, prospective ADVANCE registry. METHODS: One thousand patients with suspected angina having documented coronary artery disease on coronary CTA and clinically referred for FFRCT were prospectively enrolled in the registry...
February 2, 2018: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/29415207/progression-of-calcium-density-in-the-ascending-thoracic-aorta-is-inversely-associated-with-incident-cardiovascular-disease-events
#15
Isac C Thomas, Robyn L McClelland, Matthew A Allison, Joachim H Ix, Erin D Michos, Nketi I Forbang, Wendy S Post, Nathan D Wong, Matthew J Budoff, Michael H Criqui
Aims: Little is known regarding the risk of atherosclerotic cardiovascular disease (ASCVD) conferred by changes in the volume and density of ascending thoracic aorta calcium (ATAC) over time. We evaluated changes in ATAC volume and density scores and incident ASCVD events. Methods and results: The Multi-Ethnic Study of Atherosclerosis is a prospective cohort study of individuals without baseline clinical ASCVD. Ascending thoracic aorta calcium was measured from baseline and follow-up (mean interval 2...
February 5, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29414260/computed-tomography-scanning-for-early-detection-of-lung-cancer
#16
Francine L Jacobson, Michael T Jaklitsch
Parallel and often unrelated developments in health care and technology have all been necessary to bring about early detection of lung cancer and the opportunity to decrease mortality from lung cancer through early detection of the disease by computed tomography. Lung cancer screening programs provide education for patients and clinicians, support smoking cessation as primary prevention for lung cancer, and facilitate health care for tobacco-associated diseases, including cardiovascular and chronic lung diseases...
January 29, 2018: Annual Review of Medicine
https://www.readbyqxmd.com/read/29413496/subclinical-atherosclerosis-in-adults-with-steady-state-bronchiectasis-a-case-control-study
#17
Yong-Hua Gao, Shao-Xia Liu, Juan-Juan Cui, Ling-Yun Wang, Ke-Qin Yin, Li Wang, Su-Ying Ding, Wei-Jie Guan, Guo-Jun Zhang
BACKGROUND AND OBJECTIVE: Bronchiectasis has been associated with increased risks of cardiovascular disease, in which early-stage endothelial dysfunction might have played pivotal roles. We aimed to investigate endothelial function in bronchiectasis patients, by measuring flow-mediated dilatation (FMD) and carotid intima-media thickness (CIMT) as compared with control subjects, and to elucidate the impact of different risk factors on subclinical atherosclerosis. METHODS: The study included 80 bronchiectasis patients and 80 age- and sex-matched healthy subjects...
January 2018: Respiratory Medicine
https://www.readbyqxmd.com/read/29413443/cardiovascular-imaging-with-18f-fluorodeoxyglucose-positron-emission%C3%A2-tomography-computed-tomography-in-patients-with-fibroinflammatory-disorders
#18
Marat Fudim, Matthew P Thorpe, Leslie L Chang, E William St Clair, Lynne M Hurwitz Koweek, Andrew Wang
No abstract text is available yet for this article.
February 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29407600/impact-of-cd14-cd16-monocytes-on-coronary-plaque-vulnerability-assessed-by-optical-coherence-tomography-in-coronary-artery-disease-patients
#19
Hiroyuki Yamamoto, Naofumi Yoshida, Toshiro Shinke, Hiromasa Otake, Masaru Kuroda, Kazuhiko Sakaguchi, Yushi Hirota, Takayoshi Toba, Hachidai Takahashi, Daisuke Terashita, Kenzo Uzu, Natsuko Tahara, Yuto Shinkura, Kouji Kuroda, Yoshinori Nagasawa, Yuichiro Nagano, Yoshiro Tsukiyama, Ken-Ichi Yanaka, Takuo Emoto, Naoto Sasaki, Tomoya Yamashita, Wataru Ogawa, Ken-Ichi Hirata
BACKGROUND AND AIMS: This study examined the impact of CD14++CD16+ monocytes on coronary plaque vulnerability, as assessed by optical coherence tomography (OCT), and investigated their association with daily glucose fluctuation. Although increased CD14++CD16+ monocyte levels have been reported to increase cardiovascular events, their impact on coronary plaque vulnerability in coronary artery disease (CAD) patients with or without diabetes mellitus (DM) remains unclear. METHODS: This prospective observational study included 50 consecutive patients with CAD, receiving lipid-lowering therapy and undergoing coronary angiography and OCT...
January 17, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29406941/cardiac-imaging-modalities-and-appropriate-use
#20
REVIEW
Paul Gabriel Peterson, Michael Berge, John P Lichtenberger, Maureen N Hood, Vincent B Ho
Cardiovascular imaging with calcium scoring computed tomography (CT), coronary CT angiography (CCTA), and cardiac MRI (CMR) have advanced rapidly over recent years. These imaging modalities have increased in availability, accessibility, and clinical practicality due to technological advances allowing for significant radiation dose reduction for high-quality CCTA and for rapid and reliable imaging techniques in CMR. Hardware and software developments are continually increasing efficiency and accuracy of postprocessing...
March 2018: Primary Care
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