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https://www.readbyqxmd.com/read/28231267/accuracy-of-optical-biometry-combined-with-placido-disc-corneal-topography-for-intraocular-lens-power-calculation
#1
Giacomo Savini, Kenneth J Hoffer, Piero Barboni, Nicole Balducci, Domenico Schiano-Lomoriello, Pietro Ducoli
PURPOSE: To investigate the accuracy of a new optical biometer for intraocular lens (IOL) power calculation in eyes undergoing cataract surgery. METHODS: Consecutive eyes of patients undergoing cataract surgery with the same IOL model were enrolled in a prospective cohort study. Axial length (AL) and corneal power were measured with an optical biometer based on optical low-coherence interferometry and Placido-disc corneal topography. IOL power was calculated with the Hoffer Q, Holladay 1 and SRK/T formulas...
2017: PloS One
https://www.readbyqxmd.com/read/28166298/estimation-of-chronic-kidney-disease-incidence-from-prevalence-and-mortality-data-in-american-indians-with-type-2-diabetes
#2
Pavithra Vijayakumar, Annika Hoyer, Robert G Nelson, Ralph Brinks, Meda E Pavkov
The objective was to estimate chronic kidney disease (CKD) incidence rates from prevalence and mortality data, and compare the estimates with observed (true) incidence rates in a well-characterized population with diabetes. Pima Indians aged 20 years and older with type 2 diabetes were followed from 1982 through 2007. CKD was defined by estimated GFR (eGFR) <60 ml/min/1.72 m2 or albumin-to-creatinine ratio (ACR) ≥30 mg/g. True CKD incidence and mortality rates were computed for the whole study period, and prevalence for the intervals 1982-1994 and 1995-2007...
2017: PloS One
https://www.readbyqxmd.com/read/28155777/-local-culture-and-community-participation-djandioba-family-planning-day-in-burkina-faso
#3
Souleymane Kaboré, Léon Blaise Savadogo, Ziemlé Clément Méda, Koabié Bakouan, Emanuel Lankoandé, Bernard Zongo, Norbert Coulibaly, Alain Kaboré, Alexandrine Boissier, Djénéba Sanon-Ouédraogo
The combination of “local culture and community participation” as implementation support for health programmes is an effective approach to reduce cultural barriers of access to health services. These events have reduced the negative impact of perceptions, erroneous beliefs and misinformation about modern contraceptive methods commonly observed in target populations.</ce:para>.
December 19, 2016: Santé Publique: Revue Multidisciplinaire Pour la Recherche et L'action
https://www.readbyqxmd.com/read/28155757/-introduction-despite-health-education-efforts-young-people-are-still-faced-with-major-health-problems-the-objective-of-this-study-was-to-assess-the-knowledge-and-attitude-regarding-hiv-prevention-and-unwanted-pregnancy-among-young-people-in-bobo-dioulasso
#4
Clétus Come Yélian Adohinzin, Nicolas Meda, Georges Anicet Ouédraogo, Adrien Marie Gaston Belem, Issiaka Sombié, Abdramane Berthé, Ngianga Bakwin Kandala, Georgette Damienne Avimadjenon, Laurence Fond-Harmant
A significant proportion of young people still has incomplete knowledge about HIV/AIDS and contraception. Actions designed to reinforce the knowledge of young people are of paramount importance. The capacities of parents and healthcare providers also need to be reinforced to improve the quality of relationship with young people.</ce:para>.
October 19, 2016: Santé Publique: Revue Multidisciplinaire Pour la Recherche et L'action
https://www.readbyqxmd.com/read/28140784/the-prevalence-serogroup-distribution-and-risk-factors-of-meningococcal-carriage-in-adolescents-and-young-adults-in-turkey
#5
Rahmi Tuna Tekin, Ener Cagri Dinleyici, Mehmet Ceyhan, Adem Karbuz, Nuran Salman, Murat Sutçu, Zafer Kurugol, Yasemin Balliel, Melda Celik, Mustafa Hacimustafaoglu, Necdet Kuyucu, Meda Kondolot, Gülnar Sensoy, Ozge Metin, Soner Sertan Kara, Meltem Dinleyici, Omer Kılıç, Cihangul Bayhan, Venhar Gurbuz, Emre Aycan, Aygun Memedova, Arzu Karli, Gulçin Bozlu, Solmaz Celebi
The serogroup epidemiology of invasive meningococcal disease (IMD), which varies considerably by geographic region and immunization schedule, changes continuously. Meningococcal carriage data are crucial for assessing IMD epidemiology and designing f potential vaccination strategies. Meningococcal seroepidemiology in Turkey differs from that in other countries: serogroups W and B are the predominant strains for IMD during childhood, whereas no serogroup C cases were identified over the last 10 years and no adolescent peak for IMD was found...
January 31, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28115736/an-algorithm-recommendation-for-the-pharmacological-management-of-allergic-rhinitis-in-the-uk-a-consensus-statement-from-an-expert-panel
#6
REVIEW
Brian Lipworth, Jon Newton, Bhaskar Ram, Iain Small, Jürgen Schwarze
Allergic rhinitis is a frequent presenting problem in primary care in the UK, and has increased in prevalence over the last 30 years. When symptomatic, patients report significant reduction in their quality of life and impairment in school and work performance. Achieving adequate symptom control is pivotal to successful allergic rhinitis management, and relies mostly on pharmacotherapy. While it is recognised that most mild-moderate allergic rhinitis symptoms can be managed successfully in primary care, important gaps in general practitioner training in relation to allergic rhinitis have been identified...
December 2017: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/28034414/the-effect-of-short-message-system-sms-reminder-on-adherence-to-a-healthy-diet-medication-and-cessation-of-smoking-among-adult-patients-with-cardiovascular-diseases
#7
Laila M Akhu-Zaheya, Wa'ed Y Shiyab
BACKGROUND: Cardiovascular Disease is the leading cause of death worldwide. Non-adherence to a recommended regimen among patients with Cardiovascular Diseases represents a significant problem which could lead to an increase in Cardiovascular Diseases. PURPOSE: This study aimed to assess the effects of Short Message System (SMS) reminders on adherence to a healthy diet, medication, and cessation of smoking among adult patients with Cardiovascular Diseases. METHODS: Randomized controlled trial design with three groups was used for this study...
February 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28018917/micronucleated-erythrocytes-in-peripheral-blood-from-neonate-rats-exposed-by-breastfeeding-to-cyclophosphamide-colchicine-or-cytosine-arabinoside
#8
Belinda C Gómez-Meda, Luis R Bañales-Martínez, Ana L Zamora-Perez, María de Lourdes Lemus-Varela, Xóchitl Trujillo, María G Sánchez-Parada, Blanca M Torres-Mendoza, Juan Armendáriz-Borunda, Guillermo M Zúñiga-González
Genotoxic exposure to chemical substances is common, and nursing mothers could transmit harmful substances or their metabolites to their offspring through breast milk. We explored the possibility of determining genotoxic effects in the erythrocytes of breastfeeding rat pups whose mothers received a genotoxic compound while nursing. Ten groups of female rats and five pups per dam were studied. The control group received sterile water, and the experimental groups received one of three different doses of cyclophosphamide, colchicine, or cytosine-arabinoside...
2016: BioMed Research International
https://www.readbyqxmd.com/read/28017910/nutrition-knowledge-and-mediterranean-diet-adherence-in-the-southeast-united-states-validation-of-a-field-based-survey-instrument
#9
Mary Rose Bottcher, Patricia Z Marincic, Katie L Nahay, Brittany E Baerlocher, Amy W Willis, Jieun Park, Philippe Gaillard, Michael W Greene
The Mediterranean diet (MD) can reduce chronic disease risk and is a recommended diet for prevention and management of diabetes. Adherence to the MD in the southeast United States where obesity and diabetes are highly prevalent is unknown. The purpose of the present study was to: 1) construct a survey instrument relevant to the general population integrating both MD related nutrition knowledge and adherence questions from previously validated instruments, and 2) assess MD related nutrition knowledge and adherence in a sample population in the southest United States...
December 23, 2016: Appetite
https://www.readbyqxmd.com/read/28006000/glibenclamide-prevents-diabetes-in-nod-mice
#10
Smaragda Lamprianou, Conny Gysemans, Joanna Bou Saab, Helena Pontes, Chantal Mathieu, Paolo Meda
Previous work has revealed that Cx36, the sole connexin expressed in the insulin-producing beta cells, enhances the secretion of insulin, and promotes the resistance of beta cells against pro-inflammatory cytokines. In parallel, the anti-diabetic sulphonylurea glibenclamide was shown to promote the assembly and function of Cx36 channels. Here, we assessed whether glibenclamide could protect the insulin-producing cells against conditions mimicking those expected at the onset of type 1 diabetes. We found that the drug 1) protected in vitro the mouse MIN6 cells from the apoptosis and loss of Cx36, which are induced by Th1 cytokines; 2) prevented the development of hyperglycemia as well as the loss of beta cells and Cx36, which rapidly develop with aging in untreated NOD mice; 3) modified the proportion of effector CD4+ and CD8+ T cells in pancreatic draining lymph nodes...
2016: PloS One
https://www.readbyqxmd.com/read/28002526/micro-ct-and-optical-microscopy-imagistic-investigations-of-root-canal-morphology
#11
Emanuela Lidia Crăciunescu, Marius Boariu, Ciprian IoniŢă, Daniela Maria Pop, Cosmin Sinescu, Mihai Romînu, Meda Lavinia NegruŢiu
Protecting the root's internal morphology is the first key toward the success of the endodontic treatment. Due to the vast diversity of endodontic space, it is difficult to visualize and to establish the shape and limits of the root canal, especially the morphology of apical area and lateral root canals. Optical microscopy is a classical imagistic investigation method, widely used along classical methods like radiographs that also offer limited information about root morphology and extension of decay. Micro-computed tomography (micro-CT), a modern imagistic investigation method can provide detailed three-dimensional reconstructions of root canal...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28002510/caspase-3-expression-and-plasma-level-of-fas-ligand-as-apoptosis-biomarkers-in-inflammatory-endotoxemic-lung-injury
#12
Raluca Ştefania Fodor, Anca Meda Georgescu, Bianca Liana Grigorescu, Adrian Dan Cioc, Mihaly Veres, Ovidiu Simion Cotoi, Pal Fodor, Sanda Maria Copotoiu, Leonard Azamfirei
OBJECTIVE: The objective of this study is to evaluate if the immunohistochemical expression of a pulmonary apoptosis marker and plasma level of Fas ligand (FasL) correlates with the dose- and time-dependent severity of lung injury, induced by the administration of lipo-polysaccharide (LPS) in an endotoxemic rat model. MATERIALS AND METHODS: Our study included 30 male Wistar rats, randomly divided into three groups: one control group (n=6) and two experimental groups (n=12÷group), in whom we induced endotoxemia by intraperitoneal injection of progressively increasing doses of LPS (5, 10 mg÷kg)...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27943298/a-physiologically-based-pharmacokinetic-model-for-chickens-exposed-to-feed-supplemented-with-monensin-during-their-lifetime
#13
J Henri, R Carrez, B Méda, M Laurentie, P Sanders
We developed a flow-limited physiologically based pharmacokinetic model for residues of monensin in chickens and evaluated its predictive ability by comparing it with an external data set describing concentration decays after the end of treatment. One advantage of this model is that the values for most parameters (34 of 38) were taken directly from the literature or from field data (for growth and feed intake). Our model included growth (changes in body weight) to describe exposure throughout the life of the chicken...
December 12, 2016: Journal of Veterinary Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/27938530/surgical-management-of-gynecomastia-experience-of-a-general-surgery-center
#14
A Longheu, F Medas, F Corrias, S Farris, A Tatti, G Pisano, E Erdas, P G Calò
AIM: Gynecomastia is a common finding in male population of all ages. The aim of our study was to present our experience and goals in surgical treatment of gynecomastia. PATIENTS AND METHODS: Clinical records of patients affected by gynecomastia referred to our Department of Surgery between September 2008 and January 2015 were analyzed. 50 patients were included in this study. RESULTS: Gynecomastia was monolateral in 12 patients (24%) and bilateral in 38 (76%); idiopathic in 41 patients (82%) and secondary in 9 (18%)...
July 2016: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/27922171/connexins-and-pannexins-from-biology-towards-clinical-targets
#15
Paolo Meda, Jacques-Antoine Haefliger
Efficient cell communication is a prerequisite for the coordinated function of tissues and organs. In vertebrates, this communication is mediated by a variety of mechanisms, including the exchange of molecules between cells, and between cells and the extracellular medium, via membrane channels made of connexin and pannexin proteins. These channels are a necessary component of all human tissues. Here, we review the biological essentials of the connexin and pannexin families, and the roles of these proteins in the function of cells which are central to major human diseases...
2016: Swiss Medical Weekly
https://www.readbyqxmd.com/read/27908286/cost-analysis-of-large-scale-implementation-of-the-helping-babies-breathe-newborn-resuscitation-training-program-in-tanzania
#16
Sumona Chaudhury, Lauren Arlington, Shelby Brenan, Allan Kaijunga Kairuki, Amunga Robson Meda, Kahabi G Isangula, Victor Mponzi, Dunstan Bishanga, Erica Thomas, Georgina Msemo, Mary Azayo, Alice Molinier, Brett D Nelson
BACKGROUND: Helping Babies Breathe (HBB) has become the gold standard globally for training birth-attendants in neonatal resuscitation in low-resource settings in efforts to reduce early newborn asphyxia and mortality. The purpose of this study was to do a first-ever activity-based cost-analysis of at-scale HBB program implementation and initial follow-up in a large region of Tanzania and evaluate costs of national scale-up as one component of a multi-method external evaluation of the implementation of HBB at scale in Tanzania...
December 1, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27895016/are-prophylactic-and-therapeutic-target-concentrations-different-the-case-of-lopinavir-ritonavir-or-lamivudine-administered-to-infants-for-prevention-of-mother-to-child-hiv-1-transmission-during-breastfeeding
#17
Frantz Foissac, Jörn Blume, Jean-Marc Tréluyer, Thorkild Tylleskär, Chipepo Kankasa, Nicolas Meda, James K Tumwine, Mandisa Singata-Madliki, Kim Harper, Silvia M Illamola, Naïm Bouazza, Nicolas Nagot, Philippe Van de Perre, Stéphane Blanche, Déborah Hirt
The ANRS 12174 trial assessed the efficacy and tolerance of lopinavir (LPV)-ritonavir (LPV/r) prophylaxis versus those of lamivudine (3TC) prophylaxis administered to breastfed infants whose HIV-infected mothers were not on antiretroviral therapy. In this substudy, we assessed LPV/r and 3TC pharmacokinetics to evaluate the percentage of infants with therapeutic plasma concentrations and to discuss these data in the context of a prophylactic treatment. Infants from the South African trial site underwent blood sampling for pharmacokinetic study at weeks 6, 26, and 38 of life...
February 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/27889159/exposure-to-minimally-processed-pear-and-melon-during-shelf-life-could-modify-the-pathogenic-potential-of-listeria-monocytogenes
#18
Pilar Colás-Medà, Inmaculada Viñas, Márcia Oliveira, Marina Anguera, Jose C E Serrano, Maribel Abadias
Survival and virulence of foodborne pathogens can be influenced by environmental factors such as the intrinsic properties of food as well as the extrinsic properties that contribute to food shelf life (e.g., temperature and gas atmosphere). The direct contribution of food matrix characteristics on the survival of L. monocytogenes during fresh-cut fruit shelf life is not very well understood. In addition, the gastrointestinal tract is the primary route of listeriosis infection and penetration of the intestinal epithelial cell barrier is the first step in the infection process...
April 2017: Food Microbiology
https://www.readbyqxmd.com/read/27882840/a-comparison-of-health-care-resource-utilization-and-costs-for-patients-with-allergic-rhinitis-on-single-product-or-free-combination-therapy-of-intranasal-steroids-and-intranasal-antihistamines
#19
Brooke Harrow, Ahmad R Sedaghat, Amanda Caldwell-Tarr, Robert Dufour
BACKGROUND: Allergic rhinitis (AR) is a common condition that can be treated with a number of different therapies. Treatments such as intranasal antihistamines (INAs) and intranasal steroids (INSs) are widely used by AR patients. For some allergy sufferers, a combination of therapies, specifically an INA and an INS, is required to address their symptoms. A new treatment, the formulation of azelastine hydrochloride and fluticasone pro-pionate used as a single spray (MP-AzeFlu), has become available for AR patients who need both types of treatment...
December 2016: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/27870761/disease-activity-score-on-28-joints-and-polypharmacy-are-independent-predictors-for-health-related-quality-of-life-evaluated-by-incavisa-in-patients-with-rheumatoid-arthritis
#20
Linda Mariana González-Gamboa, Ana Karen Barocio-Ramírez, Alberto Daniel Rocha-Muñoz, Fabiola de Santos-Ávila, Rosa M Meda-Lara, Laura González-López, Jorge Iván Gámez-Nava, Eduardo Gómez-Bañuelos, Efrain Chavarria-Avila, Sergio Durán-Barragán, Rosa Elena Navarro-Hernández, Oscar Enrique Pizano-Martínez, Lourdes Nuñez-Atahualpa, Mónica Vázquez-Del Mercado
OBJECTIVE: The aim of this study was to investigate the main factors associated to a diminished health-related quality of life (HRQoL) evaluated by INCAVISA (Health-Related Quality of Life Inventory for Latin American Patients) in patients with rheumatoid arthritis (RA). METHODS: Female, 18 years or older, RA (American College of Rheumatology 1987 criteria and American College of Rheumatology/European League against Rheumatism 2010 criteria) patients who attended the outpatient rheumatology department of the Hospital Civil "Dr...
December 2016: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
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