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https://www.readbyqxmd.com/read/28424860/influence-of-tibial-hybrid-fixation-on-graft-tension-and-stability-in-acl-double-bundle-reconstruction
#1
B H Drews, A Seitz, J Huth, G Bauer, A Ignatius, L Dürselen
PURPOSE: Initial graft tension in anterior cruciate ligament (ACL) reconstruction affects stability and tension loss at follow-up. This study investigated the influence of hybrid tibial fixation in 3-tunnel double-bundle ACL reconstruction on initial graft tension and tension change and stability under anterior and combined rotatory loads. METHODS: Eleven fresh-frozen cadaveric knees were reconstructed with an ACL double bundle using a 3-tunnel technique. Grafts were tightened to 80 N in 60° (AM bundle) and 15° (PL bundle) of flexion...
April 19, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28421358/vitamin-d-supplementation-for-the-management-of-knee-osteoarthritis-a-systematic-review-of-randomized-controlled-trials
#2
Salman Hussain, Ambrish Singh, Mohd Akhtar, Abul Kalam Najmi
Conflicting evidence exists concerning the supplementation of vitamin D in knee osteoarthritis condition. This systematic literature review was done to explore the effects of vitamin D supplementation in the management of knee osteoarthritis. Electronic literature search was done in databases like PubMed(®), Embase(®), and Cochrane CENTRAL from inception to 6th July 2016. The quality of included Randomized Controlled Trials (RCTs) was assessed using Cochrane risk of bias tool. We considered change in Western Ontario and McMaster Universities (WOMAC) index, Visual Analog Scale (VAS) and Functional Pain Score (FPS) as the primary outcome measure...
April 18, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28418574/inadequacy-of-joint-aspiration-for-detection-of-persistent-periprosthetic-infection-during-two-stage-septic-revision-knee-surgery
#3
Bernd Preininger, Viktor Janz, Philipp von Roth, Andrej Trampuz, Carsten F Perka, Tilman Pfitzner
Despite the lack of validation, synovial aspiration remains a common practice during 2-stage septic revision total knee arthroplasty (TKA). The goal of this study was to investigate the diagnostic validity of synovial polymethylmethacrylate (PMMA) spacer aspiration of temporary knee arthrodesis to detect persistent periprosthetic joint infection before TKA reimplantation. This retrospective cohort study included 73 consecutive patients who underwent 2-stage septic revision TKA according to a standard protocol...
April 18, 2017: Orthopedics
https://www.readbyqxmd.com/read/28413771/management-of-aromatase-inhibitor-associated-bone-loss-aibl-in-postmenopausal-women-with-hormone-sensitive-breast-cancer-joint-position-statement-of-the-iof-cabs-ects-ieg-esceo-ims-and-siog
#4
REVIEW
Peyman Hadji, Matti S Aapro, Jean-Jacques Body, Michael Gnant, Maria Luisa Brandi, Jean Yves Reginster, M Carola Zillikens, Claus-C Glüer, Tobie de Villiers, Rod Baber, G David Roodman, Cyrus Cooper, Bente Langdahl, Santiago Palacios, John Kanis, Nasser Al-Daghri, Xavier Nogues, Erik Fink Eriksen, Andreas Kurth, Rene Rizzoli, Robert E Coleman
BACKGROUND: Several guidelines have been reported for bone-directed treatment in women with early breast cancer (EBC) for averting fractures, particularly during aromatase inhibitor (AI) therapy. Recently, a number of studies on additional fracture related risk factors, new treatment options as well as real world studies demonstrating a much higher fracture rate than suggested by randomized clinical controlled trials (RCTs). Therefore, this updated algorithm was developed to better assess fracture risk and direct treatment as a position statement of several interdisciplinary cancer and bone societies involved in the management of AI-associated bone loss (AIBL)...
June 2017: Journal of Bone Oncology
https://www.readbyqxmd.com/read/28407660/the-effects-of-calcium-vitamins-d-and-k-co-supplementation-on-markers-of-insulin-metabolism-and-lipid-profiles-in-vitamin-d-deficient-women-with-polycystic-ovary-syndrome
#5
Maryam Karamali, Mahnaz Ashrafi, Maryamalsadat Razavi, Mehri Jamilian, Maryam Kashanian, Maryam Akbari, Zatollah Asemi
Data on the effects of calcium, vitamins D and K co-supplementation on markers of insulin metabolism and lipid profiles among vitamin D-deficient women with polycystic ovary syndrome (PCOS) are scarce. This study was done to determine the effects of calcium, vitamins D and K co-supplementation on markers of insulin metabolism and lipid profiles in vitamin D-deficient women with PCOS. This randomized double-blind, placebo-controlled trial was conducted among 55 vitamin D-deficient women diagnosed with PCOS aged 18-40 years old...
April 13, 2017: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/28402447/infectious-disease-dynamics-inferred-from-genetic-data-via-sequential-monte-carlo
#6
R A Smith, E L Ionides, A A King
Genetic sequences from pathogens can provide information about infectious disease dynamics that may supplement or replace information from other epidemiological observations. Most currently available methods first estimate phylogenetic trees from sequence data, then estimate a transmission model conditional on these phylogenies. Outside limited classes of models, existing methods are unable to enforce logical consistency between the model of transmission and that underlying the phylogenetic reconstruction. Such conicts in assumptions can lead to bias in the resulting inferences...
April 8, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/28392152/how-exercise-influences-equine-joint-homeostasis
#7
REVIEW
Nikae C R Te Moller, P René van Weeren
The maintenance of joint homeostasis is integral to joint health. Knowledge of the influence of exercise on joint homeostasis is not only relevant for determining sustainable levels of equine athletic training, but also for the study of early development of osteoarthritis or cartilage repair in animal models. This review provides an overview of findings derived from in vivo studies and postmortem analyses investigating exercise effects on various joint tissue components in the horse, supplemented where appropriate with data from small animal models...
March 28, 2017: Veterinary Journal
https://www.readbyqxmd.com/read/28388531/stiffness-and-proprioceptive-contributions-of-ankle-braces-and-the-influence-of-localized-muscle-fatigue
#8
Courtney A Webster, Maury A Nussbaum, Michael L Madigan
Ankle braces are a common treatment to reduce ankle sprain recurrence among individuals with chronic ankle instability (CAI). Bracing provides supplemental external joint stiffness and/or improved proprioceptive acuity. The goals of this study were to assess the effects of two ankle braces on joint position sense (JPS) and ankle stiffness, and determine whether bracing effects are reduced with localized muscle fatigue. Measures of JPS and ankle stiffness were obtained from participants with CAI (n=12) for three conditions (no brace, a neoprene wrap brace, and a semi-rigid brace), before and after inducing localized muscle fatigue at the ankle...
March 2, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/28384524/reliability-and-validity-of-the-dsm-5-anxious-distress-specifier-interview
#9
Mark Zimmerman, Heather Clark, Patrick McGonigal, Lauren Harris, Carolina Guzman Holst, Jacob Martin
BACKGROUND: To acknowledge the clinical significance of anxiety in depressed patients, DSM-5 included an anxious distress specifier for major depressive disorder (MDD). In the present report we describe the reliability and validity of a semi-structured interview assessing the features of the anxious distress specifier. Our goal was to develop an instrument that could be used for both diagnostic and outcome measurement purposes. METHODS: One hundred seventy-three psychiatric patients with MDD were interviewed by a trained diagnostic rater who administered the Structured Clinical Interview for DSM-IV (SCID) supplemented with questions from the DSM-5 Anxious Distress Specifier Interview (DADSI)...
March 2, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28384173/daily-oral-consumption-of-hydrolyzed-type-1-collagen-is-chondroprotective-and-anti-inflammatory-in-murine-posttraumatic-osteoarthritis
#10
Qurratul-Ain Dar, Eric M Schott, Sarah E Catheline, Robert D Maynard, Zhaoyang Liu, Fadia Kamal, Christopher W Farnsworth, John P Ketz, Robert A Mooney, Matthew J Hilton, Jennifer H Jonason, Janne Prawitt, Michael J Zuscik
Osteoarthritis (OA) is a degenerative joint disease for which there are no disease modifying therapies. Thus, strategies that offer chondroprotective or regenerative capability represent a critical unmet need. Recently, oral consumption of a hydrolyzed type 1 collagen (hCol1) preparation has been reported to reduce pain in human OA and support a positive influence on chondrocyte function. To evaluate the tissue and cellular basis for these effects, we examined the impact of orally administered hCol1 in a model of posttraumatic OA (PTOA)...
2017: PloS One
https://www.readbyqxmd.com/read/28376768/long-term-effects-of-vitamin-d-supplementation-in-vitamin-d-deficient-obese-children-participating-in-an-integrated-weight-loss-programme-a-double-blind-placebo-controlled-study-rationale-for-the-study-design
#11
Agnieszka Szlagatys-Sidorkiewicz, Michał Brzeziński, Agnieszka Jankowska, Paulina Metelska, Magdalena Słomińska-Frączek, Piotr Socha
BACKGROUND: Obesity is associated not only with an array of metabolic disorders (e.g. insulin resistance, hiperinsulinemia, impaired tolerance of glucose, lipid disorders) but also skeletal and joint abnormalities. Recently, a pleiotropic role of vitamin D has been emphasized. Obese children frequently present with vitamin D deficiency, and greater fat mass is associated with lower serum concentration of this vitamin. Although some evidence suggests that weight loss may affect vitamin D status, this issue has not been studied extensively thus far...
April 4, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28370209/clinical-instruments-and-methods-for-assessing-physical-oral-health-a-systematic-review
#12
L-K Pauli, G Aarabi, L Kriston, A Jansen, G Heydecke, D R Reissmann
OBJECTIVE: This study aimed at exploring available clinical instruments and methods for assessing physical oral health, and at identifying those with sufficient diagnostic performance. METHODS: A systematic literature search was conducted in Embase and MEDLINE. Identified instruments and methods were critically appraised, and quality of diagnostic performance was rated by two independent reviewers as A (sufficient diagnostic performance), B (either sufficient reliability or validity) or C (insufficient quality, or empirical results unsatisfactory and/or inconsistent)...
March 31, 2017: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/28368931/vitamin-d-and-tibiofemoral-joint-orientation-angles-in-children
#13
Nedal Alkhatib, Fadi Bouri, Abdelsalam Hegazy, Talal Ibrahim
Vitamin D is an important component in musculoskeletal development and function in children. The aim of our study was to investigate vitamin D levels and tibiofemoral joint orientation angles in children. We performed a retrospective review on a consecutive series of children presenting with lower limb complaints. The children underwent an assessment of serum vitamin D level and full-length standing lower limb anteroposterior radiographs, and were divided into normal and deficient vitamin D groups. Tibiofemoral angles (TFAs) [lateral distal femoral angle (LDFA); medial proximal tibial angle (MPTA)] were measured by three independent observers and compared between the groups...
March 31, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28366315/prevention-of-periprosthetic-joint-infection-examining-the-recent-guidelines
#14
Noam Shohat, Javad Parvizi
BACKGROUND: The global rise in infectious disease has led the Center for Disease Control and Prevention and the World Health Organization to release new guidelines for the prevention of surgical site infection. METHODS: In this article, we summarize current recommendations based on level of evidence, review unresolved and unaddressed issues, and supplement them with new literature. RESULTS: Although the guidelines discuss major issues in reducing surgical site infection, many questions remain unanswered...
March 6, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28361713/the-joint-nettab-integrative-bioinformatics-2015-meeting-aims-topics-and-outcomes
#15
EDITORIAL
Paolo Romano, Ralf Hofestädt, Matthias Lange, Domenica D'Elia
The 15(th) International NETTAB workshop and the 11(th) Integrative Bioinformatics Symposium were held together in Bari, on October 14-16, 2016, as Joint NETTAB/IB 2015 Meeting. A special topic for the meeting was "Bioinformatics for ncRNA", but the traditional topics of both meetings series were also included in the event.About 60 scientific contributions were presented, including six keynote lectures, one special guest lecture, and many oral communications and posters. A "Two-Day Hands-on Tutorial" event was organised before the workshop...
March 23, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28351509/adequate-calcium-intake-during-long-periods-improves-bone-mineral-density-in-healthy-children-data-from-the-childhood-obesity-project
#16
Ricardo Closa-Monasterolo, Marta Zaragoza-Jordana, Natàlia Ferré, Veronica Luque, Veit Grote, Berthold Koletzko, Elvira Verduci, Fiammetta Vecchi, Joaquin Escribano
BACKGROUND: Bone mineralization can be influenced by genetic factors, hormonal status, nutrition, physical activity and body composition. The association of higher calcium (Ca) intake or Ca supplementation with better bone mineral density (BMD) remains controversial. Furthermore, it has been speculated that maintaining long-term adequate Ca intake rather than having a brief supplementation period is more effective. The aim of the study was to prospectively analyse the influence of adequate Ca intake on BMD at 7 years of age in European children...
March 16, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28350759/resveratrol-supplementation-reduces-pain-experience-by-postmenopausal-women
#17
Rachel H X Wong, Hamish M Evans, Peter R C Howe
OBJECTIVE: Pain is a common complaint among postmenopausal women. It has been postulated that vascular dysfunction caused by estrogen decline at menopause plays a key role in the initiation and progression of degradative joint disease, namely age-related osteoarthritis. We evaluated whether supplementation with resveratrol, a phytoestrogen, could improve aspects of well-being such as chronic pain that is commonly experienced by postmenopausal women. METHODS: A 14-week randomized, double-blind, placebo-controlled intervention with trans-resveratrol (75 mg, twice daily) was conducted in 80 healthy postmenopausal women...
March 27, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28346333/clinical-benefits-of-n-3-pufa-and-%C3%A9-linolenic-acid-in-patients-with-rheumatoid-arthritis
#18
Mirjana Veselinovic, Dragan Vasiljevic, Vesna Vucic, Aleksandra Arsic, Snjezana Petrovic, Aleksandra Tomic-Lucic, Maja Savic, Sandra Zivanovic, Vladislava Stojic, Vladimir Jakovljevic
(1) Background: Marine n-3 polyunsaturated fatty acids (PUFA) and ɤ-linolenic acid (GLA) are well-known anti-inflammatory agents that may help in the treatment of inflammatory disorders. Their effects were examined in patients with rheumatoid arthritis; (2) Methods: Sixty patients with active rheumatoid arthritis were involved in a prospective, randomized trial of a 12 week supplementation with fish oil (group I), fish oil with primrose evening oil (group II), or with no supplementation (group III). Clinical and laboratory evaluations were done at the beginning and at the end of the study; (3) Results: The Disease Activity Score 28 (DAS 28 score), number of tender joints and visual analogue scale (VAS) score decreased notably after supplementation in groups I and II (p < 0...
March 25, 2017: Nutrients
https://www.readbyqxmd.com/read/28344755/effect-of-topical-application-of-nigella-sativa-oil-and-oral-acetaminophen-on-pain-in-elderly-with-knee-osteoarthritis-a-crossover-clinical-trial
#19
Akram Kooshki, Reza Forouzan, Mohammad Hassan Rakhshani, Maryam Mohammadi
BACKGROUND: Limited evidence supports Nigella sativa's role as an effective complementary and alternative medicine and the anti-inflammatory effects of Nigella sativa on patients with allergic rhinitis. OBJECTIVE: The aim of this study was to investigate the effect of topical application of Nigella sativa oil and oral acetaminophen on pain in the elderly with knee osteoarthritis residing in a parents' home in Sabzevar. METHODS: This study is done as a crossover clinical trial...
November 2016: Electronic Physician
https://www.readbyqxmd.com/read/28336154/socioeconomic-and-therapy-factor-influence-on-self-reported-fatigue-anxiety-and-depression-in-rheumatoid-arthritis-patients
#20
Mirjana Lapčević, Mira Vuković, Branislav S Gvozdenović, Vesna Mioljević, Snežana Marjanović
INTRODUCTION: Fatigue, anxiety and depression are very frequent symptoms in patients with rheumatoid arthritis (RA). GOALS: In this study we evaluated the influence of socioeconomic characteristics, therapy and comorbidities on the self-reported high fatigue, anxiety and depression in patients with RA. METHOD: Multicenter cross-sectional study was performed in 22 health institutions in Serbia during the period from April-August 2014 in population of older RA patients...
February 27, 2017: Revista Brasileira de Reumatologia
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