keyword
MENU ▼
Read by QxMD icon Read
search

joint supplement

keyword
https://www.readbyqxmd.com/read/28303758/beneficial-effect-of-n-3-polyunsaturated-fatty-acids-on-inflammation-and-analgesic-use-in-psoriatic-arthritis-a-randomized-double-blind-placebo-controlled-trial
#1
S Kristensen, E B Schmidt, A Schlemmer, C Rasmussen, M B Johansen, J H Christensen
OBJECTIVE: This study aimed to investigate the effects of marine n-3 polyunsaturated fatty acids (PUFAs) on disease activity, use of analgesics, and inflammatory biomarkers in patients with psoriatic arthritis (PsA). METHOD: Patients with established PsA (n = 145) were investigated in a randomized, double-blind, placebo-controlled study. The participants received a supplement of 3 g n-3 PUFA/day or 3 g olive oil/day (control) for 24 weeks. Outcome measures for disease activity, use of analgesics, and leukotriene formation from activated granulocytes were assessed at baseline and at study end...
March 17, 2017: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/28302406/docosahexaenoic-acid-in-the-treatment-of-rheumatoid-arthritis-a%C3%A2-double-blind-placebo-controlled-randomized-cross-over-study-with-microalgae-vs-sunflower-oil
#2
C Dawczynski, M Dittrich, T Neumann, K Goetze, A Welzel, P Oelzner, S Völker, A M Schaible, F Troisi, L Thomas, S Pace, A Koeberle, O Werz, P Schlattmann, S Lorkowski, G Jahreis
The potential of fish or fish oil as supplier for eicosapentaenoic acid (EPA, C20:5n3) and docosahexaenoic acid (DHA, C22:6n3) for reducing cardiovascular risk factors and supporting therapy of chronic inflammatory diseases, has been investigated intensively, but our knowledge about the physiological effects of the individual compounds EPA and DHA are limited. STUDY DESIGN: In this double-blind pilot study, thirty-eight patients with defined RA were allocated to consume foods enriched with microalgae oil from Schizochytrium sp...
March 6, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28300758/methylsulfonylmethane-applications-and-safety-of-a-novel-dietary-supplement
#3
REVIEW
Matthew Butawan, Rodney L Benjamin, Richard J Bloomer
Methylsulfonylmethane (MSM) has become a popular dietary supplement used for a variety of purposes, including its most common use as an anti-inflammatory agent. It has been well-investigated in animal models, as well as in human clinical trials and experiments. A variety of health-specific outcome measures are improved with MSM supplementation, including inflammation, joint/muscle pain, oxidative stress, and antioxidant capacity. Initial evidence is available regarding the dose of MSM needed to provide benefit, although additional work is underway to determine the precise dose and time course of treatment needed to provide optimal benefits...
March 16, 2017: Nutrients
https://www.readbyqxmd.com/read/28281772/response-of-cattle-with-clinical-osteochondrosis-to-mineral-supplementation
#4
RANDOMIZED CONTROLLED TRIAL
Gerjan Van der Veen, Geoffrey T Fosgate, Frederick K Botha, Heinz H Meissner, Lubbe Jacobs, Leon Prozesky
Since 1982, farmers in the North West province and other parts of South Africa have noticed an increase in the incidence of lameness in cattle. Macro- and microscopical lesions of joints resembled osteochondrosis. Pre-trial data indicated that cattle with osteochondrotic lesions recovered almost completely when fed a supplement containing bio-available micro- and macrominerals of high quality. In the present trial, 43 clinically affected cattle of varying ages (1-5 years) and sexes were randomly divided into three groups...
February 24, 2017: Onderstepoort Journal of Veterinary Research
https://www.readbyqxmd.com/read/28274889/knee-effusion-synovitis-volume-measurement-and-effects-of-vitamin-d-supplementation-in-patients-with-knee-osteoarthritis
#5
X Wang, F Cicuttini, X Jin, A E Wluka, W Han, Z Zhu, L Blizzard, B Antony, T Winzenberg, G Jones, C Ding
OBJECTIVE: To develop a measure of knee joint effusion-synovitis volume and to examine the effect of vitamin D supplementation on effusion-synovitis in patients with knee osteoarthritis (OA) and low vitamin D levels over 24 months. METHOD: Symptomatic knee OA patients with a low 25-(OH)D level (12.5-60 nmol/l) were recruited for a multi-centre, randomised, placebo-controlled and double-blind trial. Participants (age 63 ± 7 years, 208 females) were allocated to either 50,000 IU monthly vitamin D3 (n = 209) or placebo (n = 204) for 24 months...
March 6, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28261616/the-protective-effect-of-chrysanthemum-indicum-extract-against-ankylosing-spondylitis-in-mouse-models
#6
Mei Dong, Dongsheng Yu, Veeramuthu Duraipandiyan, Naif Abdullah Al-Dhabi
In traditional Chinese and Korean homeopathic medicine, Chrysanthemum indicum Linné (Asteraceae) is a time-honored herb, prescribed for the resolution of symptoms associated with inflammatory and hypertensive conditions as well as those affecting the lungs and its associated structures. The goal of this work is to investigate the defensive role of Chrysanthemum indicum extract in fighting ankylosing spondylitis (AS) using mouse models, through which the manifestation and extent of the disease progression were measured with quantitative analysis of the intervertebral joints...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28258078/a-short-term-low-magnesium-diet-reduces-autoimmune-arthritis-severity-and-synovial-tissue-gene-expression
#7
Max Brenner, Teresina Laragione, Percio S Gulko
Magnesium has been suggested to have anti-inflammatory properties in short-term mostly in vitro studies. To examined the effect of dietary magnesium modifications in arthritis severity and joint damage DA rats were placed on one of three diet regimens before the induction of autoimmune pristane-induced arthritis (PIA): a four-week low-magnesium diet, normal diet and a magnesium-supplemented diet. The diets were switched to a normal diet fourteen days after the induction of PIA (typical time of disease onset)...
March 3, 2017: Physiological Genomics
https://www.readbyqxmd.com/read/28250278/glucosamine-suppresses-osteoclast-differentiation-through-the-modulation-of-glycosylation-including-o-glcnacylation
#8
Tomoharu Takeuchi, Aya Sugimoto, Nao Imazato, Mayumi Tamura, Sachie Nakatani, Kenji Kobata, Yoichiro Arata
Osteoclasts represent the only bone resorbing cells in an organism. In this study, we investigated the effect of glucosamine (GlcN), a nutrient used to prevent joint pain and bone loss, on the osteoclastogenesis of murine macrophage-like RAW264 cells. GlcN supplementation suppressed the upregulation of osteoclast-specific genes (tartrate-resistant acid phosphatase (TRAP), cathepsin K, matrix metallopeptidase 9, and nuclear factor of activated T cell c1 (NFATc1)), receptor activator of nuclear factor-κB ligand (RANKL)-dependent upregulation of TRAP enzyme activity, and the formation of TRAP-positive multinuclear cells more effectively than N-acetylglucosamine (GlcNAc), which we have previously shown to inhibit osteoclast differentiation...
2017: Biological & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28249967/atypical-femoral-fractures-related-to-bisphosphonate-treatment-issues-and-controversies-related-to-their-surgical-management
#9
A Koh, E Guerado, P V Giannoudis
AIMS: Treatment guidelines for atypical femoral fractures associated with bisphosphonates have not been established. We conducted a systematic review of the treatment of atypical femoral fractures first, to evaluate the outcomes of surgical fixation of complete atypical fractures and secondly, to assess whether prophylactic surgery is necessary for incomplete atypical fractures. MATERIALS AND METHODS: Case reports and series were identified from the PubMed database and were included if they described the treatment of atypical femoral fractures...
March 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28245746/cervical-traction-for-managing-neck-pain-a-survey-of-physical-therapists-in-the-united-states
#10
Timothy J Madson, John H Hollman
Study Design Cross-sectional survey. Objective To examine the use of traction by physical therapists for patients with neck pain, including how and when traction is used, the delivery modes and parameters, supplemental interventions, and influence of professional demographics on usage. Background Systematic reviews provide little support for traction in managing neck pain. While traction usage among physical therapists in other countries has been described, usage in the United States has not been examined. Methods A random sample of 4000 Orthopaedic Section members of the American Physical Therapy Association were surveyed...
March 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28245338/boswellia-serrata-resin-extract-alleviates-azoxymethane-aom-dextran-sodium-sulfate-dss-induced-colon-tumorigenesis
#11
Ya-Chun Chou, Joon Hyuk Suh, Yu Wang, Manoj Pahwa, Vladimir Badmeav, Chi-Tang Ho, Min-Hsiung Pan
SCOPE: Boswellia serrata (BS) resin is a popular dietary supplement for joint nourishment. In this study, we investigated the chemopreventive effects of dietary BS extract and its impact of gut microbiota on azoxymethane/dextran sulfate sodium (AOM/DSS)-induced colitis-associated colon cancer in mice. METHODS AND RESULTS: Male ICR mice were injected with AOM and 2% DSS via drinking water. The mice were fed with 0.25% or 0.5% BS extract, and colonic tissue were collected at 15 wk...
February 28, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28243364/biomechanical-assessment-of-stabilization-of-simulated-type-ii-odontoid-fracture-with-case-study
#12
Roy T Daniel, Mir M Hussain, Noelle Klocke, Soumya S Yandamuri, Lukas Bobinski, John M Duff, Brandon S Bucklen
STUDY DESIGN: Researchers created a proper type II dens fracture (DF) and quantified a novel current posterior fixation technique with spacers at C1-C2. A clinical case study supplements this biomechanical analysis. PURPOSE: Researchers explored their hypothesis that spacers combined with posterior instrumentation (PI) reduce range of motion significantly, possibly leading to better fusion outcomes. OVERVIEW OF LITERATURE: Literature shows that the atlantoaxial joint is unique in allowing segmental rotary motion, enabling head turning...
February 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/28235439/implementation-of-community-wide-teen-pregnancy-prevention-initiatives-focus-on-partnerships
#13
Heather D Tevendale, Taleria R Fuller, L Duane House, Deborah L Dee, Emilia H Koumans
Seeking to reduce teen pregnancy and births in communities with rates above the national average, the Centers for Disease Control and Prevention, in partnership with the U.S. Department of Health and Human Services Office of Adolescent Health Teen Pregnancy Prevention Program, developed a joint funding opportunity through which grantees worked to implement and test an approach involving community-wide teen pregnancy prevention initiatives. Once these projects had been in the field for 2.5 years, Centers for Disease Control and Prevention staff developed plans for a supplemental issue of the Journal of Adolescent Health to present findings from and lessons learned during implementation of the community-wide initiatives...
March 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28222030/sub-chronic-indomethacin-treatment-and-its-effect-on-the-male-reproductive-system-of-albino-rats-possible-protective-role-of-black-tea-extract
#14
Ishwar B Bagoji, Gavishiddappa A Hadimani, Saeed M Yendigeri, Kusal K Das
BACKGROUND: Indomethacin is commonly used as a nonsteroidal anti-inflammatory drug (NSAID) to treat inflammation, arthritis and joint pains. Unfortunately, it has a wide range of adverse effects on the physiological system, including gonads. This study aimed to assess possible beneficial effects of black tea extract (BTE) against indomethacin-induced alteration of gonadal hormone levels in male rats. MATERIALS AND METHODS: Adult male rats were divided into Group I (control), Group II (indomethacin, 5 mg/kg body weight [bwt...
February 21, 2017: Journal of Basic and Clinical Physiology and Pharmacology
https://www.readbyqxmd.com/read/28202745/plasma-levels-of-eicosapentaenoic-acid-are-associated-with-anti-tnf-responsiveness-in-rheumatoid-arthritis-and-inhibit-the-etanercept-driven-rise-in-th17-cell-differentiation-in-vitro
#15
Louisa Jeffery, Helena L Fisk, Philip C Calder, Andrew Filer, Karim Raza, Christopher D Buckley, Iain McInnes, Peter C Taylor, Benjamin A Fisher
OBJECTIVE: To determine whether levels of plasma n-3 polyunsaturated fatty acids are associated with response to antitumor necrosis factor (anti-TNF) agents in rheumatoid arthritis (RA), and whether this putative effect may have its basis in altering anti-TNF-driven Th17 cell differentiation. METHODS: Plasma was collected at baseline and after 3 months of anti-TNF treatment in 22 patients with established RA, and fatty acid composition of the phosphatidylcholine (PC) component was measured...
February 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28197999/parallel-experimental-design-and-multivariate-analysis-provides-efficient-screening-of-cell-culture-media-supplements-to-improve-biosimilar-product-quality
#16
David Brühlmann, Michael Sokolov, Alessandro Butté, Markus Sauer, Jürgen Hemberger, Jonathan Souquet, Hervé Broly, Martin Jordan
Rational and high-throughput optimization of mammalian cell culture media has a great potential to modulate recombinant protein product quality. We present a process design method based on parallel design-of-experiment (DoE) of CHO fed-batch cultures in 96-deepwell plates to modulate monoclonal antibody (mAb) glycosylation using medium supplements. To reduce risk of losing valuable information in an intricate joint screening, 17 compounds were separated into five different groups, considering their mode of biological action...
February 15, 2017: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/28196322/ecosystem-services-mapping-for-sustainable-agricultural-water-management-in-california-s-central-valley
#17
Edward Matios, Jennifer Burney
Accurate information on agricultural water needs and withdrawals at appropriate spatial and temporal scales remains a key limitation to joint water and land management decision-making. We use InVEST ecosystem service mapping to estimate water yield and water consumption as functions of land use in Fresno County, a key farming region in California's Central Valley. Our calculations show that in recent years (2010-2015), the total annual water yield for the county has varied dramatically from ∼0.97 to 5.37 km(3) (all ±17%; 1 MAF ≈ 1...
February 24, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28177710/improvement-of-activity-related-knee-joint-discomfort-following-supplementation-of-specific-collagen-peptides
#18
Denise Zdzieblik, Steffen Oesser, Albert Gollhofer, Daniel Koenig
The aim of the study was to evaluate the use of specific collagen peptides in reducing pain in athletes with functional knee problems during sport. 139 athletic subjects with functional knee pain ingested 5 g of bioactive collagen peptides (BCP) or a placebo per day for 12 weeks. The primary outcome of the study was a change in pain intensity during activity was evaluated by the participants and the attending physicians using a visual analogue scale (VAS). As secondary endpoints, pain intensity under resting conditions, the range of motion (ROM) of the knee joint, and the use of additional therapeutic options were assessed...
January 24, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28174685/effects-of-arthrocen-an-avocado-soy-unsaponifiables-agent-on-inflammatory-mediators-and-gene-expression-in-human-chondrocytes
#19
Ramin Goudarzi, Jared F Taylor, Puya G Yazdi, Brian A Pedersen
Osteoarthritis (OA) is a chronic joint disease characterized by pain and stiffness. Recently, there has been great interest in the use of plant-derived compounds and supplements in managing the symptoms of OA. Arthrocen is a plant-based supplement consisting of avocado and soy unsaponifiable extracts in a 1 : 2 ratio. In an effort to unravel the potential mechanisms of its action on the cellular level, we utilized an in vitro assay to study its effects on cultured human chondrocytes. By pairing this assay with protein arrays on inflammatory markers, RNA-Seq with downstream pathway analysis, and lipidomics on eicosanoids, we were able to further define its action at the molecular level...
February 2017: FEBS Open Bio
https://www.readbyqxmd.com/read/28174189/sternal-stress-fracture-in-a-middle-aged-woman
#20
Justin Lee, Karl Bertrand Fields
A middle-aged premenopausal woman presented with 3 months of right chest wall pain after beginning a new weight training programme. Examination was significant only for mild-to-moderate tenderness to palpation over the right pectoral muscle and sternoclavicular joint. In-office musculoskeletal ultrasound scan, chest X-ray and shoulder X-rays were unremarkable. Subsequent MRI of the chest wall showed oedema in the sternum at the level of the sternoclavicular joint consistent with a sternal stress fracture...
February 7, 2017: BMJ Case Reports
keyword
keyword
115699
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"