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https://www.readbyqxmd.com/read/29145536/the-effects-of-vitamin-d-supplementation-in-newly-diagnosed-type-1-diabetes-patients-systematic-review-of-randomized-controlled-trials
#1
Elina Gregoriou, Ioannis Mamais, Irene Tzanetakou, Giagkos Lavranos, Stavri Chrysostomou
AIM: The aim of this study was to examine the effects of vitamin D supplementation in patients newly diagnosed with type 1 diabetes (T1D) assessed by insulin needs and changes in glycemic indices, as evidenced by randomized controlled trials (RCTs). METHODS: A total of 7 RCTs were retrieved from PubMed/Medline and EBSCO databases by MeSH term search, and were reviewed systematically. The RCTs included examined the effects of alphacalcidole (n = 2), cholecalciferol (n = 2), and calcitriol (n = 3) supplementation on changes in daily insulin dose (DID), fasting Cpeptide (FCP), stimulated C-peptide (SCP), and HbA1c...
July 2017: Review of Diabetic Studies: RDS
https://www.readbyqxmd.com/read/29144812/increased-bone-turnover-in-type-2-diabetes-patients-randomized-to-bariatric-surgery-vs-medical-therapy-at-5-years
#2
Megan R Crawford, Nathan Pham, Leila Khan, James F Bena, Philip R Schauer, Sangeeta R Kashyap
OBJECTIVE: The aim of our study was to determine the 5 year outcomes of bariatric surgery vs. intensive medical therapy on bone turnover in patients with type 2 diabetes (T2DM) from the STAMPEDE trial. METHODS: This is an ancillary investigation of a 5 year randomized control trial at a single tertiary care center involving 95 patients aged 48.5 ± 8 years with obesity (BMI: 36.5±3.6 kg/m(2)) and uncontrolled T2DM (HbA1C: 9.3 ±1.6%). Patients were randomized to intensive medical therapy (IMT; N=25), Roux-en-Y gastric bypass (RYGB; N=37), or sleeve gastrectomy (SG; N=33) for diabetes treatment...
November 16, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/29129039/combined-diet-and-exercise-interventions-for-preventing-gestational-diabetes-mellitus
#3
REVIEW
Emily Shepherd, Judith C Gomersall, Joanna Tieu, Shanshan Han, Caroline A Crowther, Philippa Middleton
BACKGROUND: Gestational diabetes mellitus (GDM) is associated with a wide range of adverse health consequences for women and their infants in the short and long term. With an increasing prevalence of GDM worldwide, there is an urgent need to assess strategies for GDM prevention, such as combined diet and exercise interventions. This is an update of a Cochrane review that was first published in 2015. OBJECTIVES: To assess the effects of diet interventions in combination with exercise interventions for pregnant women for preventing GDM, and associated adverse health consequences for the mother and her infant/child...
November 13, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29128995/a-systematic-review-of-dietary-interventions-for-gestational-weight-gain-and-gestational-diabetes-in-overweight-and-obese-pregnant-women
#4
REVIEW
Reeta Lamminpää, Katri Vehviläinen-Julkunen, Ursula Schwab
PURPOSE: The number of overweight and obese women is increasing in the obstetric population. The aim of this study was to review studies that reported results related to the efficacy of dietary interventions on gestational weight gain (GWG) or the prevention of gestational diabetes (GDM) in overweight and obese women. METHODS: The search was performed using the CINAHL, PubMed, Scopus and Medic electronic databases and limited to the years between 2000 and March 2016...
November 11, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/29125636/very-tight-versus-tight-control-which-should-be-the-criteria-for-pharmacologic-therapy-dose-adjustment-in-diabetes-in-pregnancy-evidence-from-randomized-controlled-trials
#5
Claudia Caissutti, Gabriele Saccone, Andrea Ciardulli, Vincenzo Berghella
INTRODUCTION: There is inconclusive evidence from randomized controlled trials (RCTs) to support any specific criteria for pharmacologic therapy dose adjustment in diabetes in pregnancy. Our objective was to analyze the criteria for dose adjustment of pharmacologic treatment for diabetes mellitus (DM) in pregnancy. MATERIAL AND METHODS: Data sources: MEDLINE, OVID and Cochrane Library were searched from their inception to September 2017. Selection criteria included all trials of DM in pregnancy managed by oral hypoglycemic agents or insulin reporting criteria for pharmacologic therapy dose adjustment...
November 10, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29125183/ovarian-surgery-for-symptom-relief-in-women-with-polycystic-ovary-syndrome
#6
REVIEW
Sam Lepine, Junyoung Jo, Mostafa Metwally, Ying C Cheong
BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrine condition, affecting approximately one in 10 women. PCOS is defined by two of three features: oligo- or anovulation, clinical or biochemical hyperandrogenism or both, or polycystic ovaries.Women with PCOS can have a wide range of health problems, including infrequent and irregular periods, unwanted hair growth and acne, and subnormal fertility. Long-term health concerns include an increased risk of heart disease, diabetes and the development of precancerous disease of the womb...
November 10, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29123401/psychosocial-intervention-for-patients-with-type-2-diabetes-mellitus-and-comorbid-depression-a-meta-analysis-of-randomized-controlled-trials
#7
Jing Xie, Wuquan Deng
Background: The efficacy of psychosocial intervention has been proven in treatment of diabetic patients with depression in some studies. This meta-analysis was conducted to explore the efficacy as well as additional effects of this method during diabetic management in patients with type 2 diabetes mellitus (T2DM) and comorbid depression. Methods: Electronic databases were searched from March 2000 to March 2017 for randomized controlled trials (RCTs) studying the effects of psychosocial intervention on T2DM patients with depression...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29103664/canagliflozin-in-conjunction-with-sulfonylurea-maintains-glycemic-control-and-weight-loss-over-52-weeks-a-randomized-controlled-trial-in-patients-with-type-2-diabetes-mellitus
#8
Jean-François Yale, John Xie, Stephen E Sherman, Claude Garceau
PURPOSE: Our aim was to investigate the long-term efficacy and safety of canagliflozin, a sodium-glucose co-transporter 2 inhibitor, added to background sulfonylurea (SU) monotherapy for patients with type 2 diabetes mellitus. METHODS: The CANagliflozin cardioVascularAssessment Study (CANVAS) was a double-blind, placebo-controlled cardiovascular outcomes study that randomly assigned participants to receive placebo or canagliflozin 100 or 300 mg once daily in addition to routine therapy...
November 2, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/29092883/a-systematic-review-and-meta-analysis-of-nutrition-therapy-compared-with-dietary-advice-in-patients-with-type-2-diabetes
#9
Grith Møller, Henning Keinke Andersen, Ole Snorgaard
Background: Despite recommendations, many patients with type 2 diabetes receive dietary advice from nurses or doctors instead of individualized nutrition therapy (INT) that is provided by a dietitian.Objective: We performed a meta-analysis to compare the effect of INT that is provided by a registered dietitian with the effect of dietary advice that is provided by other healthcare professionals.Design: A systematic review was conducted of Cochrane library databases, EMBASE, CINAHL, and MEDLINE in the period 2004-2017 for guidelines, reviews, and randomized controlled trials (RCTs) that assessed the outcomes glycated hemoglobin (HbA1c), weight, body mass index (BMI; in kg/m(2)), and LDL cholesterol...
November 1, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29092881/effects-of-potassium-supplements-on-glucose-metabolism-in-african-americans-with-prediabetes-a-pilot-trial
#10
Ranee Chatterjee, Cris Slentz, Clemontina A Davenport, Johanna Johnson, Pao-Hwa Lin, Michael Muehlbauer, David D'Alessio, Laura P Svetkey, David Edelman
Background: Low potassium has been identified both as a risk factor for type 2 diabetes and as a mediator of the racial disparity in diabetes risk. Low potassium could be a potentially modifiable risk factor, particularly for African Americans.Objective: We sought to determine the effects of potassium chloride (KCl) supplements, at a commonly prescribed dose, on measures of potassium and glucose metabolism.Design: Among African-American adults with prediabetes, we conducted a double-blinded pilot randomized controlled trial that compared the effects of 40 mEq K/d as KCl supplements with a matching placebo, taken for 3 mo, on measures of potassium and glucose metabolism, with measures collected from frequently sampled oral-glucose-tolerance tests (OGTTs)...
November 1, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29090600/comparison-between-insulin-degludec-liraglutide-treatment-and-insulin-glargine-lixisenatide-treatment-in-type-2-diabetes-a-systematic-review-and-meta-analysis
#11
Xiaoling Cai, Xueying Gao, Wenjia Yang, Linong Ji
AIM: To evaluate the efficacy and adverse effects of IDegLira and IGlarLixi treatment and to perform a comparison between two strategies. METHODS: The registration number is CRD42017053952. Randomized controlled trials of IGlarLixi treatment or IDegLira treatment compared with placebo or active hypoglycemic agents in type 2 diabetes were included. RESULTS: Eight trials were included. The absolute HbA1c change relative to baseline after IGlarLixi treatment was -1...
November 1, 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/29081069/different-methods-and-settings-for-glucose-monitoring-for-gestational-diabetes-during-pregnancy
#12
REVIEW
Puvaneswary Raman, Emily Shepherd, Therese Dowswell, Philippa Middleton, Caroline A Crowther
BACKGROUND: Incidence of gestational diabetes mellitus (GDM) is increasing worldwide. Blood glucose monitoring plays a crucial part in maintaining glycaemic control in women with GDM and is generally recommended by healthcare professionals. There are several different methods for monitoring blood glucose which can be carried out in different settings (e.g. at home versus in hospital). OBJECTIVES: The objective of this review is to compare the effects of different methods and settings for glucose monitoring for women with GDM on maternal and fetal, neonatal, child and adult outcomes, and use and costs of health care...
October 29, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29078817/long-term-effects-of-high-dose-pitavastatin-on-diabetogenicity-in-comparison-with-atorvastatin-in-patients-with-metabolic-syndrome-less-dm-study-protocol-for-a-randomized-controlled-trial
#13
Jun-Bean Park, Ji-Hyun Jung, Yeonyee E Yoon, Hack-Lyong Kim, Seung-Pyo Lee, Hyung-Kwan Kim, Yong-Jin Kim, Goo-Yeong Cho, Dae-Won Sohn
BACKGROUND: The diabetogenic action of statins remains a concern, particularly in patients at high risk for diabetes receiving intensive statin therapy. Despite the risk of diabetes with statin use being considered a potential class effect, recent studies have suggested that pitavastatin exerts neutral or favorable effects on diabetogenicity. However, no randomized trial has compared the long-term effects of pitavastatin with those of other statins on glycemic control in populations at high risk for diabetes...
October 27, 2017: Trials
https://www.readbyqxmd.com/read/29072812/anti-interleukin-1-therapy-has-mild-hypoglycemic-effect-in-type-2-diabetes
#14
Jinya Huang, Yehong Yang, Renming Hu, Lili Chen
OBJECTIVE: To systematically evaluate the efficacy and safety of anti-interleukin-1 therapy for type 2 diabetes. METHODS: A literature search from Pubmed and Embase for available trials on anti-interleukin-1 therapy in type 2 diabetes was performed. The baseline characteristics, changes of HbA1c and other metabolic parameters and adverse events were extracted from included randomized controlled trials (RCTs) and analyzed with Review Manager. Mean differences (MDs) and 95% CIs were calculated to measure differences of metabolic parameters...
October 26, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/29069022/prevalence-risk-factors-and-prognostic-significance-of-masked-hypertension-in-diabetic-patients
#15
Honglei Zhao, Fanfang Zeng, Xiang Wang, Lili Wang
The aims of present study were to evaluate the prevalence, risk factors, and prognostic significance of masked hypertension in diabetic patients. Using a cross-sectional design, 266 patients with documented type 2 diabetes mellitus and clinic blood pressure (BP) <140/90 mm Hg without antihypertension treatment were enrolled; 24-hour ambulatory BP monitoring was applied to evaluate mean 24-hour systolic/diastolic BP. Demographics, medical histories, and medications usage were obtained using questionnaire...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29067243/treating-psychological-insulin-resistance-in-type-2-diabetes
#16
Nancy A Allen, Sofija E Zagarins, Rebecca G Feinberg, Garry Welch
AIMS: The phenomenon of psychological insulin resistance (PIR) has been well documented for two decades, but interventions to treat PIR have not been well described. The aim of this study was to describe interventions used to treat psychological insulin resistance by certified diabetes educators (CDE's). METHODS: A secondary data analysis study using empirical data from a trial (N = 234) that included four CDEs providing counseling for psychological insulin resistance...
March 2017: Journal of Clinical & Translational Endocrinology
https://www.readbyqxmd.com/read/29067058/effect-of-vitamin-d-supplementation-on-reduction-in-levels-of-hba1-in-patients-recently-diagnosed-with-type-2-diabetes-mellitus-having-asymptomatic-vitamin-d-deficiency
#17
Fawad Ahmad Randhawa, Saqib Mustafa, Dur Muhammad Khan, Shahid Hamid
OBJECTIVE: To study the effect of Vitamin D supplementation on reduction in level of HbA1 in patients recently diagnosed with diabetes mellitus Type II having asymptomatic Vitamin D deficiency. METHODS: This randomized control trial was conducted at East Medical Ward Mayo Hospital Lahore for 6 months from January 01 2016 to June 30, 2016. 114 Patients were included through non probability purposive sampling technique. Informed consent and demographic information was collected...
July 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29061552/designing-a-self-management-app-for-young-people-with-type-1-diabetes-methodological-challenges-experiences-and-recommendations
#18
Pernille Castensøe-Seidenfaden, Gitte Reventlov Husted, Grete Teilmann, Eva Hommel, Birthe Susanne Olsen, Finn Kensing
BACKGROUND: Young people with type 1 diabetes often struggle to self-manage their disease. Mobile health (mHealth) apps show promise in supporting self-management of chronic conditions such as type 1 diabetes. Many health care providers become involved in app development. Unfortunately, limited information is available to guide their selection of appropriate methods, techniques, and tools for a participatory design (PD) project in health care. OBJECTIVE: The aim of our study was to develop an mHealth app to support young people in self-managing type 1 diabetes...
October 23, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29059214/effect-of-glycemic-control-and-type-of-diabetes-treatment-on-unsuccessful-tb-treatment-outcomes-among-people-with-tb-diabetes-a-systematic-review
#19
REVIEW
Hemant Deepak Shewade, Kathiresan Jeyashree, Preetam Mahajan, Amar N Shah, Richard Kirubakaran, Raghuram Rao, Ajay M V Kumar
BACKGROUND: Stringent glycemic control by using insulin as a replacement or in addition to oral hypoglycemic agents (OHAs) has been recommended for people with tuberculosis and diabetes mellitus (TB-DM). This systematic review (PROSPERO 2016:CRD42016039101) analyses whether this improves TB treatment outcomes. OBJECTIVES: Among people with drug-susceptible TB and DM on anti-TB treatment, to determine the effect of i) glycemic control (stringent or less stringent) compared to poor glycemic control and ii) insulin (only or with OHAs) compared to 'OHAs only' on unsuccessful TB treatment outcome(s)...
2017: PloS One
https://www.readbyqxmd.com/read/29059017/baseline-characteristics-and-technology-training-of-underserved-adults-with-type-2-diabetes-in-the-mobile-diabetes-detective-modd-randomized-controlled-trial
#20
Elizabeth M Heitkemper, Lena Mamykina, Jonathan N Tobin, Andrea Cassells, Arlene Smaldone
Purpose The purpose of this study is to describe the characteristics and technology training needs of underserved adults with type 2 diabetes mellitus (T2DM) who participated in a health information technology (HIT) diabetes self-management education (DSME) intervention. Methods The baseline physiological, psychosocial, and technology use characteristics for 220 adults with poorly controlled T2DM were evaluated. Intervention participants received a 1-time intervention training, which included basic technology help, introduction to the Mobile Diabetes Detective (MoDD) website and text message features, and account activation that included subject-specific tailoring...
December 2017: Diabetes Educator
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