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https://www.readbyqxmd.com/read/28436326/evaluation-and-characterization-of-nutritive-properties-of-the-jelly-ear-culinary-medicinal-mushroom-auricularia-auricula-judae-agaricomycetes-from-nigeria
#1
Reginald Chibueze Ohiri, Essien Eka Bassey
This study investigated the nutritive properties of the culinary-medicinal mushroom Auricularia auricula- judae. From the analysis, among the major minerals, potassium was found in the highest concentration, with a value of 172.03 ± 8.62 mg/kg, whereas manganese had the highest concentration among trace elements, with a value of 1.66 ± 0.11 mg/kg. Glutamic acid was the amino acid detected in the largest amounts in this study, with a value of 10.09 ± 1.86 mg/kg. Although glutamine and asparagine were not detected in this mushroom, cysteine and methionine had the lowest concentrations, with values of 0...
2017: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/28372550/complementary-and-alternative-medicine-use-results-from-a-descriptive-study-of-pregnant-women-in-udi-local-government-area-of-enugu-state-nigeria
#2
Jane-Lovena Onyiapat, Chinyelu Okafor, Ijeoma Okoronkwo, Agnes Anarado, Ekene Chukwukelu, Ada Nwaneri, Pat Okpala
BACKGROUND: The use of CAM by pregnant women is very popular in developed countries. The trend is increasing globally and lack of evidence of safety particularly when used during pregnancy may lead to complications. Pregnancy is a vulnerable period especially during the first trimester. There is scarcity of empirical evidence on CAM use particularly among women in Udi LGA of Enugu State and South East Nigeria. Moreover, studies carried out in Nigeria have been limited to herbal medicine use, which is one aspect of CAM...
April 4, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28357128/impact-of-comorbidity-on-adverse-drug-reaction-profile-in-a-cohort-of-patients-treated-with-artemisinin-combination-therapies-for-uncomplicated-malaria-in-nigeria
#3
Peter U Bassi, Adeline I Osakwe, Comfort K Ogar, Cassandra Elagbaje, Biyaya B Nwankwo, Sulayman T Balogun, Godwin N Ntadom, Ambrose O Isah
Artemisinin-based combination antimalarial therapy (ACTs), is still highly effective in uncomplicated falciparum malaria, however, there remain some concerns in relation to its safety and tolerability. Comorbid disease conditions may influence susceptibility to adverse drug reactions (ADRs) as the presence of multiple disease conditions may predisposes patients to ADRs due to the use of many medicines. There is therefore need to assess the impact of comorbidities on the ADR profile of malaria patients treated with ACTs...
April 2017: Pharmacology Research & Perspectives
https://www.readbyqxmd.com/read/28336470/bioassay-guided-isolation-of-active-principles-from-nigerian-medicinal-plants-identifies-new-trypanocides-with-low-toxicity-and-no-cross-resistance-to-diamidines-and-arsenicals
#4
Godwin Unekwuojo Ebiloma, John Ogbaji Igoli, Evangelos Katsoulis, Anne-Marie Donachie, Anthonius Eze, Alexander Ian Gray, Harry P de Koning
ETHNOPHARMACOLOGICAL RELEVANCE: Leaves from the plant species studied herein are traditionally used in northern Nigeria against various protozoan infections. However, none of these herbal preparations have been standardized, nor have their toxicity to mammalian cells been investigated. In search of improved and non-toxic active antiprotozoal principles that are not cross-resistant with current anti-parasitics, we here report the results of the in vitro screening of extracts from seven selected medicinal plant species (Centrosema pubescens, Moringa oleifera, Tridax procumbens, Polyalthia longifolia, Newbouldia laevis, Eucalyptus maculate, Jathropha tanjorensis), used traditionally to treat kinetoplastid infections in Nigeria, and the isolation of their bioactive principles...
March 20, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28327163/injuries-in-male-and-female-semi-professional-football-soccer-players-in-nigeria-prospective-study-of-a-national-tournament
#5
Oluwatoyosi Babatunde Alex Owoeye, Ayoola Ibifubara Aiyegbusi, Oluwaseun Akinleye Fapojuwo, Oluwaseun Abdulganiyu Badru, Anike Rasheedat Babalola
BACKGROUND: Research on the epidemiology of football injuries in Africa is very sparse despite its importance for injury prevention planning in a continent with limited sports medicine resources. The vast majority of studies available in literature were conducted in Europe and only a very few studies have prospectively reported the pattern of football injury in Africa. The purpose of this study was to evaluate the incidence and pattern of injuries in a cohort of male and female semi-professional football players in Nigeria...
March 21, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28326840/a-new-benzophenone-glycoside-from-the-leaves-of-mitracarpus-villosus
#6
Kenneth G Ngwoke, Njideka Orame, Shuai Liu, Festus B C Okoye, Georgios Daletos, Peter Proksch
A new benzophenone glycoside, mitraphenone A (1), together with three known compounds (2-4) were isolated from the leaves of the traditionally used medicinal plant Mitracarpus villosus (Rubiaceae) collected in Nigeria. A combination of one- and two-dimensional NMR spectroscopic and mass spectrometric measurements were carried out to identify the structure of 1. All isolated compounds (1-4) were screened for their antibacterial activity against several Gram-positive and Gram-negative bacteria. Compound 1 exhibited moderate activity against Enterococcus faecium (strains ATCC 35667 and ATCC 700221) and Staphylococcus aureus ATCC 25923 with MIC values ranging from 25 to 50 μM...
March 22, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28256303/polyphenol-rich-fraction-of-parquetina-nigrescens-mitigates-dichlorvos-induced-neurotoxicity-and-apoptosis
#7
Grace Onyeche Ochigbo, Adebowale Bernard Saba, Ademola Adetokunbo Oyagbemi, Temidayo Olutayo Omobowale, Ebunoluwa Racheal Asenuga
BACKGROUND: Parquetina nigrescens (Afzel.) Bullock of the family Asclepiadaceae is known for its antioxidant effects with wide range of uses in Southwestern Nigeria especially in traditional medicine. This study was undertaken to explore if polyphenol-rich fraction (prf) from P. nigrescens will ameliorate dichlorvos-induced neurotoxicity and apoptosis. The exploration utilized evaluation of markers of oxidative stress, apoptosis and serum acetylcholinesterase (AchE) levels. METHODS: Forty Wistar rats randomly placed in four groups were utilized for the study...
January 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28207051/access-to-age-appropriate-essential-medicines-a-retrospective-survey-of-compounding-of-medicines-for-children-in-hospitals-in-nigeria-and-implications-for-policy-development
#8
Ebiowei Samuel F Orubu, Chinyere Okwelogu, Olabisi Opanuga, Tony Nunn, Catherine Tuleu
No abstract text is available yet for this article.
March 1, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28202479/improving-services-for-glaucoma-care-in-nigeria-implications-for-policy-and-programmes-to-achieve-universal-health-coverage
#9
Fatima Kyari, Clare Gilbert, Karl Blanchet, Richard Wormald
Glaucoma in Africa is sometimes referred to as the silent thief of sight. In Nigeria, glaucoma is common, it is serious, ophthalmologists face many constraints in managing it, people do not even know they have it until it is advanced, patients do not understand or comply with treatment after they are diagnosed and the poor are more likely to be glaucoma blind. Available evidence indicates that the health system in Nigeria is failing to meet the needs of patients with glaucoma. Based on evidence, we propose future directions for improving services for glaucoma care in Nigeria, and the implications for policy and programmes to control glaucoma blindness, using a health system-oriented approach...
May 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28163967/pregnancy-detecting-plants-used-in-remo-and-ijebu-areas-of-ogun-state-nigeria
#10
Adediwura Fred-Jaiyesimi, Jolaade Taiwo
AIM/BACKGROUND: Plants and plants extracts are employed in cultures for religious purposes, as beauty therapies, in the detection and management/treatment of diseases. MATERIALS AND METHODOLOGY: In this study, an ethnobotanical studies of plants used in detecting pregnancy in Ijebu and Remo areas of Ogun State were carried out using semi-structured to obtain demographic data, local names of plants, the morphological parts used. Furthermore, a phytochemical analysis of two of the identified plants was performed...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28089716/a-characterization-of-the-antimalarial-activity-of-the-bark-of-cylicodiscus-gabunensis-harms
#11
Omar Aldulaimi, Fidelia I Uche, Hamza Hameed, Haddijatou Mbye, Imran Ullah, Falko Drijfhout, Timothy D W Claridge, Paul Horrocks, Wen-Wu Li
ETHNOPHARMACOLOGICAL RELEVANCE AND AIM: A decoction of the bark of Cylicodiscus gabunensis Harms is used as a traditional medicine in the treatment of malaria in Nigeria. This study aims to validate the antimalarial potency of this decoction in vitro against Plasmodium falciparum and define potential bioactive constituents within the C. gabunensis bark. MATERIALS AND METHODS: A bioassay-guided separation and fractionation protocol was applied to C. gabunensis extracts, exploiting the use of a Malaria Sybr Green I Fluorescence assay method to monitor antiproliferative effects on parasites as well as define 50% inhibition concentrations...
January 9, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28032428/antimalarial-treatment-patterns-among-pregnant-women-attending-antenatal-care-clinics-in-south-east-nigeria-and-the-future-implications
#12
Charles Ezenduka, Chizoba Nworgu, Brian Barr Godman, Amos Massele, Charles Esimone
BACKGROUND: Prompt and effective treatment of malaria in pregnancy in accordance with recommended guidelines is essential to help prevent adverse events among pregnant mothers and the foetus. AIM: The aim of this study was to assess current prescribing of antimalarial medicines in pregnancy against policy guidelines in south east Nigeria to provide future guidance. METHODS: A review of prescription records of pregnant women treated for malaria over a 6-month period between August 2013 and January 2014 was carried out to assess the prescribing patterns for both the prevention and treatment of malaria in each trimester and analyzed for conformity to recommended guidelines...
December 2016: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/27980381/prevalence-and-predictors-of-risk-factors-for-brucellosis-transmission-by-meat-handlers-and-traditional-healers-risk-practices-in-ibadan-nigeria
#13
REVIEW
H K Adesokan, P I Alabi, M A Ogundipe
INTRODUCTION: Brucellosis is endemic in Nigeria and risk factors enhancing its transmission are prevalent. METHODS: Following serological evidence of brucellosis and isolation of B. abortus from slaughtered cattle in Ibadan, Nigeria, we administered a semi-structured questionnaire to determine the prevalence and predictors of eating and selling bovine gravid uterus among 350 meat handlers from five major meat processing facilities. We conducted key informant interview for five leading traditional healers to document its use...
September 2016: Journal of Preventive Medicine and Hygiene
https://www.readbyqxmd.com/read/27976927/interview-with-sanofi-s-dr-tunde-falode
#14
Tunde Falode
Dr Tunde Falode speaks to Elena Conroy, Commissioning Editor: Dr Tunde Falode is General Manager for the Diabetes and Cardiovascular Business Unit in the UK and Ireland at Sanofi, a global pharmaceutical company. Following graduation from the University of Jos Medical School in Nigeria, he secured a basic surgical training post through Guy's and St Thomas' hospitals in London, eventually specializing in cardiac and thoracic surgery, before changing his career path. In addition to his current role at Sanofi, he recently completed his specialist training in pharmaceutical medicine and has a keen interest in sports...
January 2017: Future Cardiology
https://www.readbyqxmd.com/read/27941102/impact-of-improving-community-based-access-to-malaria-diagnosis-and-treatment-on-household-costs
#15
Joëlle Castellani, Jesca Nsungwa-Sabiiti, Borislava Mihaylova, IkeOluwapo O Ajayi, Mohamadou Siribié, Chinenye Afonne, Andrew Balyeku, Luc Sermé, Armande K Sanou, Benjamin S Sombié, Alfred B Tiono, Sodiomon B Sirima, Vanessa Kabarungi, Catherine O Falade, Josephine Kyaligonza, Silvia M A A Evers, Aggie T G Paulus, Max Petzold, Jan Singlovic, Melba Gomes
BACKGROUND:  Community health workers (CHWs) were trained in Burkina Faso, Nigeria, and Uganda to diagnose febrile children using malaria rapid diagnostic tests, and treat positive malaria cases with artemisinin-based combination therapy (ACT) and those who could not take oral medicines with rectal artesunate. We quantified the impact of this intervention on private household costs for childhood febrile illness. METHODS:  Households with recent febrile illness in a young child in previous 2 weeks were selected randomly before and during the intervention and data obtained on household costs for the illness episode...
December 15, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/27895667/attitude-to-the-menopause-and-sex-amongst-middle-aged-women-in-a-family-medicine-clinic-in-ibadan-nigeria
#16
Folasade Adenike Bello, Olufunmilola Olutosin Daramola
Background. Menopause is the expected end of reproductive life. Having a positive attitude towards it has been shown to result in a positive experience, while a negative attitude is associated with negative experiences and symptoms. Traditionally, women often abstain from sex after menopause. The study aimed to determine the level of awareness and perceptions about the menopause and sex in perimenopausal women attending a general outpatient clinic. Methods. Women over 40 years were recruited from the Family Medicine Department of University College Hospital, excluding those who were menopausal...
2016: Obstetrics and Gynecology International
https://www.readbyqxmd.com/read/27889258/unilateral-collaboration-the-practices-and-understandings-of-traditional-birth-attendants-in-southeastern-nigeria
#17
Magdalena Ohaja, Jo Murphy-Lawless
BACKGROUND: Despite the promotion of hospital-based maternity care as the safest option, for less developed countries, many women particularly those in the rural areas continue to patronise indigenous midwives or traditional birth attendants. Little is known about traditional birth attendants' perspectives regarding their pregnancy and birth practices. AIM: To explore traditional birth attendants' discourses of their pregnancy and birthing practices in southeast Nigeria...
November 23, 2016: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/27816564/community-health-workers-provide-integrated-community-case-management-using-malaria-rapid-diagnostic-test-kits
#18
Bright C Orji, Namratha Rao, Elizabeth Thompson, William R Brieger, Emmanuel 'Dipo Otolorin
BACKGROUND: Throughout Nigeria malaria is an endemic disease. Efforts to treat malaria can also be combined with other illnesses including pneumonia and diarrhea, which are killing children under five years of age. The use of Rapid Diagnostic Test (RDT) aids early diagnosis of malaria and informs when other illnesses should be considered. Those with positive RDT results should be treated with Artemisinin-based Combination Therapy (ACTs), while those with negative RDTs results are further investigated for pneumonia and diarrhea...
October 26, 2016: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/27814763/scaling-up-the-use-of-sulfadoxine-pyrimethamine-for-the-preventive-treatment-of-malaria-in-pregnancy-results-and-lessons-on-scalability-costs-and-programme-impact-from-three-local-government-areas-in-sokoto-state-nigeria
#19
Nosa Orobaton, Anne M Austin, Dele Abegunde, Mohammed Ibrahim, Zainab Mohammed, Jumare Abdul-Azeez, Hakeem Ganiyu, Zwalle Nanbol, Bolaji Fapohunda, Katherine Beal
BACKGROUND: Intermittent preventive treatment of malaria in pregnancy with 3+ doses of sulfadoxine-pyrimethamine (IPTp-SP) reduces maternal mortality and stillbirths in malaria endemic areas. Between December 2014 and December 2015, a project to scale up IPTp-SP to all pregnant women was implemented in three local government areas (LGA) of Sokoto State, Nigeria. The intervention included community education and mobilization, household distribution of SP, and community health information systems that reminded mothers of upcoming SP doses...
November 4, 2016: Malaria Journal
https://www.readbyqxmd.com/read/27812808/the-value-of-internet-tools-in-undergraduate-surgical-education-perspective-of-medical-students-in-a-developing-country
#20
S O Ekenze, C I Okafor, O S Ekenze, J N Nwosu, U F Ezepue
OBJECTIVE: Advances in information technology (IT) in the past decade present opportunities and challenges in undergraduate surgical education. There may be need to evaluate the knowledge base and the use of Internet tools among medical students in settings where traditional mode of education is preeminent. This may help to establish a conceptual framework for integrating e-learning into the traditional teaching to enhance learning experience. In this study, we evaluated the medical students' knowledge and use of Internet tools, and their opinion on the application of these tools in surgical education...
November 3, 2016: World Journal of Surgery
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