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medicine in nigeria

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https://www.readbyqxmd.com/read/29157824/fraxetin-and-ethyl-acetate-extract-from-lawsonia-inermis-l-ameliorate-oxidative-stress-in-p-berghei-infected-mice-by-augmenting-antioxidant-defence-system
#1
Dhananjay Kumar Singh, Harveer Singh Cheema, Archana Saxena, Jyotshana, Shilpi Singh, Mahendra P Darokar, Dnyaneshwar U Bawankule, Karuna Shanker, Suaib Luqman
BACKGROUND: Lawsonia inermis L. is a well-documented plant for cosmetic as well as medicinal properties. It is used by local communities in India and Nigeria for the treatment of many parasitic diseases, including malaria. HYPOTHESIS/PURPOSE: Earlier studies on the plant's antiplasmodial activity were not assigned to any phytochemical with no quality assurance data. In this report, a recent chemically characterized extract and it's major constituent were investigated for in vitro antiplasmodial activity on chloroquine sensitive NF-54 strain...
December 1, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29078810/improving-oxygen-therapy-for-children-and-neonates-in-secondary-hospitals-in-nigeria-study-protocol-for-a-stepped-wedge-cluster-randomised-trial
#2
Hamish R Graham, Adejumoke I Ayede, Ayobami A Bakare, Oladapo B Oyewole, David Peel, Amy Gray, Barbara McPake, Eleanor Neal, Shamim Qazi, Rasa Izadnegahdar, Adegoke G Falade, Trevor Duke
BACKGROUND: Oxygen is a life-saving, essential medicine that is important for the treatment of many common childhood conditions. Improved oxygen systems can reduce childhood pneumonia mortality substantially. However, providing oxygen to children is challenging, especially in small hospitals with weak infrastructure and low human resource capacity. METHODS/DESIGN: This trial will evaluate the implementation of improved oxygen systems at secondary-level hospitals in southwest Nigeria...
October 27, 2017: Trials
https://www.readbyqxmd.com/read/29073202/questionnaire-survey-of-the-pan-african-trade-in-lion-body-parts
#3
Vivienne L Williams, Andrew J Loveridge, David J Newton, David W Macdonald
The African lion is in decline across its range, and consumptive utilisation and trade of their body parts and skins has been postulated as a cause for concern. We undertook a pan-African questionnaire and literature survey to document informed opinion and evidence for the occurrence of domestic and international trade and consumption in African lion body parts across current and former range states. Sixty-five people from 18 countries participated in the online questionnaire survey (run from July 2014 to May 2015), with information provided for 28 countries (including 20 out of 24 countries believed to have extant populations)...
2017: PloS One
https://www.readbyqxmd.com/read/29072236/knowledge-and-utilization-of-electrocardiogram-among-resident-doctors-in-family-medicine-in-nigeria
#4
G C Isiguzo, M O Iroezindu, A S Muoneme, B N Okeahialam
BACKGROUND: Electrocardiogram (ECG) is a simple, readily affordable, and noninvasive tool for the evaluation of cardiac disorders. There is a dearth of information on the utility of ECG in general practice in Nigeria. We assessed the knowledge and utilization of ECG among family medicine residents in Nigeria. MATERIALS AND METHODS: A cross-sectional evaluation was conducted between November 2011 and May 2012 in four family medicine training centers in Nigeria. A self-administered questionnaire was used to obtain information from the resident doctors regarding their ECG requests, preferred source of interpretation, most common ECG diagnosis, and update of ECG knowledge...
September 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29063634/health-care-quality-and-information-failure-evidence-from-nigeria
#5
David K Evans, Anna Welander Tärneberg
Low-quality health services are a problem across low- and middle-income countries. Information failure may contribute, as patients may have insufficient knowledge to discern the quality of health services. That decreases the likelihood that patients will sort into higher quality facilities, increasing demand for better health services. This paper presents results from a health survey in Nigeria to investigate whether patients can evaluate health service quality effectively. Specifically, this paper demonstrates that although more than 90% of patients agree with any positive statement about the quality of their local health services, satisfaction is significantly associated with the diagnostic ability of health workers at the facility...
October 23, 2017: Health Economics
https://www.readbyqxmd.com/read/29062173/effect-of-ethanolic-extract-from-seeds-or-pods-of-xylopia-aethiopica-dunal-a-rich-annonaceae-on-the-testicular-function-of-adult-male-rats
#6
Sunny O Abarikwu, Aemere Ogunlaja, Chiagoziem A Otuechere, OlatunBosun Gideon
Xylopia aethiopica (Annonaceae) is used in some folk medicines and widely consumed as a spice in some parts of Nigeria. Its efficacy as an anti-androgenic substance has warranted the attention of African scholars. This study evaluated the enzymatic activity of lactate dehydrogenase (LDH), γ-glutamyl transferase (γ-GT), sperm quality (motility, count, morphology), testosterone level and histo-pathological changes of the testis of rats chronically treated with ethanolic extract of the pods (without seeds), seeds, and fruits (pods + seeds) of Xylopia aethiopica...
October 2017: Indian Journal of Clinical Biochemistry: IJCB
https://www.readbyqxmd.com/read/29050491/some-antidiabetic-medicinal-plants-used-by-traditional-healers-in-ado-ekiti-nigeria
#7
F C Akharaiyi, A J Akinyemi, C C Isitua, O T Ogunmefun, S O Opakunle, J K Fasae
OBJECTIVES: The work described plants collection, preparation and administration for diabetes cure in Ado Ekiti in Nigeria. METHODS: Twenty three plant samples were identified for the use in the treatment of diabetes by the herbalists. The plants that are common among the healers are Anthocleista djalonensis, Vernonia amygdalina, Ocimum gratissimum, Momordica charantia. RESULTS: The most preferred method of preparation by the healers is concoction and decoction of fresh leaves, stem bark and roots...
2017: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/28980008/challenges-and-barriers-for-implementation-of-the-world-health-organization-global-disability-action-plan-in-low-and-middle-income-countries
#8
Fary Khan, Mayowa Ojo Owolabi, Bhasker Amatya, Talhatu Kolapo Hamzat, Adesola Ogunniyi, Helen Oshinowo, Alaeldin Elmalik, Mary P Galea
OBJECTIVE: To identify potential barriers and facilitators for implementation of the World Health Organization Global Disability Action Plan (GDAP) in Nigeria and compare these with other low- and middle-income countries. METHODS: A rehabilitation team from the Royal Melbourne Hospital, Parkville, Australia, conducted intensive workshops at medical/academic institutions in Nigeria for healthcare professionals from various local Physical Medicine and Rehabilitation facilities...
October 5, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28976064/benefits-and-extent-of-cam-use-among-persons-living-with-hiv-attending-an-antiretroviral-therapy-clinic-in-warri-nigeria
#9
Ufuoma S Ahwinahwi, Valentine U Odili, Jeremiah Ogubere
PURPOSE: The objective of this study was to assess the use of complementary and alternative medicine (CAM) therapies among patients on anti-retroviral therapies as well as the possible reasons for their use. METHOD: This cross-sectional survey was conducted with the aid of an interviewer-administered questionnaire on HIV-positive patients attending the antiretroviral therapy clinic (Heart-to-Heart centre) of the Central Hospital, Warri, Nigeria. Patients who were 18 years and over were included after a brief introductory talk on the nature of the study...
October 4, 2017: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28971606/methionine-and-vitamin-b-complex-ameliorate-antitubercular-drugs-induced-toxicity-in-exposed-patients
#10
Kennedy I Amagon, Olufunsho Awodele, Abidemi J Akindele
Tuberculosis therapy utilizes drugs that while effective cause treatment-related toxicity. Modulation of antitubercular drugs-induced toxicity by methionine and vitamin B-complex in patients was evaluated. 285 treatment-naïve tuberculosis patients at the Chest Clinics of Infectious Diseases Hospital, Yaba and General Hospital, Lagos in Lagos, Nigeria was prospectively recruited and allotted into test (antitubercular medicines, methionine and vitamin B-complex) and control groups (antitubercular medicines)...
October 2017: Pharmacology Research & Perspectives
https://www.readbyqxmd.com/read/28955102/social-support-treatment-adherence-and-outcome-among-hypertensive-and-type-2-diabetes-patients-in-ambulatory-care-settings-in-southwestern-nigeria
#11
Rasaq Adisa, Olamide O Olajide, Titilayo O Fakeye
OBJECTIVES: To evaluate available and desired sources and types of social-support among hypertensive and type-2-diabetes (T2D) patients. Associations of medication adherence and clinical outcome with access to most available social-support and medicine affordability were subsequently investigated. DESIGN: Cross-sectional questionnaire-guided interview among 250-hypertensive and 200-T2D patients, and review of medical records to retrieve disease-specific clinical parameters...
June 2017: Ghana Medical Journal
https://www.readbyqxmd.com/read/28930265/a-review-on-ethno-medicinal-and-pharmacological-activities-of-sphenocentrum-jollyanum-pierre
#12
REVIEW
Olubukola Sinbad Olorunnisola, Olumide Samuel Fadahunsi, Peter Adegbola
Sphenocentrum jollyanum Pierre is a member of a diverse family of plants known as Menispermaceae. They are famous for a plethora of important biological functions. S. jollyanum is a shrub native to the tropical forest zones of West Africa and thrives in deep shade. It is widely cultivated in Cameroun, Sierra Leone, Nigeria, Ghana, and Côte d'Ivoire. S. jollyanum is employed in folk medicine as a cure for wounds, fever, coughs, high blood pressure, breast tumor, constipation, and as an aphrodisiac. Phytochemical investigations revealed that the plant is a rich source of secondary metabolites such as annin, alkaloids, saponins, and flavonoids...
July 3, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28930239/eryngium-foetidum-l-essential-oils-chemical-composition-and-antioxidant-capacity
#13
Paul S Thomas, Emmanuel E Essien, Samuel J Ntuk, Mohammad I Choudhary
Background:Eryngium foetidum essential oils from Nigeria were investigated for the first time in order to ascertain their potency as natural antioxidants. E. foetidum is an aromatic and medicinal herb used in ethno-medicine and as a traditional spice for foods. Methods: The hydro-distilled oils of E. foetidum were subjected to gas chromatography-mass spectrometry (GC-MS) analysis. Free radical scavenging capacity of the volatile oils was determined using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays...
April 28, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28903757/access-to-medicines-and-hepatitis-c-in-africa-can-tiered-pricing-and-voluntary-licencing-assure-universal-access-health-equity-and-fairness
#14
Yibeltal Assefa, Peter S Hill, Anar Ulikpan, Owain D Williams
BACKGROUND: The recent introduction of Direct Acting Antivirals (DAAs) for treating Hepatitis C Virus (HCV) can significantly assist in the world reaching the international target of elimination by 2030. Yet, the challenge facing many individuals and countries today lies with their ability to access these treatments due to their relatively high prices. Gilead Sciences applies differential pricing and licensing strategies arguing that this provides fairer and more equitable access to these life-saving medicines...
September 13, 2017: Globalization and Health
https://www.readbyqxmd.com/read/28888089/antidiabetic-potential-of-polyphenolic-rich-fraction-of-tamarindus-indica-seed-coat-in-alloxan-induced-diabetic-rats
#15
Santosh Singh Bhadoriya, Aditya Ganeshpurkar, Ravi Pratap Singh Bhadoriya, Sanjeev Kumar Sahu, Jay Ram Patel
BACKGROUND: Tamarindus is a monotypic genus and belongs to the subfamily Caesalpinioideae of the family Leguminosae (Fabaceae), Tamarindus indica L., commonly known as Tamarind tree is one of the most important multipurpose tropical fruit tree species in the India, Sudan, Nigeria, Bangladesh and entire subcontinent. METHODS: Hydroethanolic seed coat extract of Tamarindus indica (HETI) was assessed for presence of phytoconstituents and selection of optimum dose through acute and sub acute toxicity study...
September 9, 2017: Journal of Basic and Clinical Physiology and Pharmacology
https://www.readbyqxmd.com/read/28877208/surveillance-for-falsified-and-substandard-medicines-in-africa-and-asia-by-local-organizations-using-the-low-cost-gphf-minilab
#16
Albert Petersen, Nadja Held, Lutz Heide
BACKGROUND: Substandard and falsified medical products present a serious threat to public health, especially in low- and middle-income countries. Their identification using pharmacopeial analysis is expensive and requires sophisticated equipment and highly trained personnel. Simple, low-cost technologies are required in addition to full pharmacopeial analysis in order to accomplish widespread routine surveillance for poor-quality medicines in low- and middle-income countries. METHODS: Ten faith-based drug supply organizations in seven countries of Africa and Asia were each equipped with a Minilab of the Global Pharma Health Fund (GPHF, Frankfurt, Germany), suitable for the analysis of about 85 different essential medicines by thin-layer chromatography...
2017: PloS One
https://www.readbyqxmd.com/read/28843873/the-islamification-of-antiretroviral-therapy-reconciling-hiv-treatment-and-religion-in-northern-nigeria
#17
Jack Ume Tocco
Access and adherence to antiretroviral therapy (ART) are essential to HIV treatment success and epidemic control. This article is about how HIV-positive Muslims and providers balance ART with religious tenets and obligations. I conducted 17 months of multi-site ethnographic research between 2007 and 2010, including participant-observation in an urban HIV clinic in Kano, Nigeria and a support group for people living with HIV, as well as in-depth interviews with 30 HIV-positive men and 30 key informants with caregiving, clinical, or policy roles related to HIV/AIDS...
August 18, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28803088/temporary-removal-treat-the-pain-program
#18
Megan O'Brien, Amanda Schwartz, Laura Plattner
The publisher regrets that this article has been temporarily removed. A replacement will appear as soon as possible in which the reason for the removal of the article will be specified, or the article will be reinstated. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal.
August 10, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28703962/haematological-and-biochemical-studies-on-justicia-carnea-leaves-extract-in-phenylhydrazine-induced-anemia-in-albino-rats
#19
Chimaraoke Onyeabo, Ngozi K Achi, Chima A Ekeleme-Egedigwe, Chidinma U Ebere, Chidinma K Okoro
BACKGROUND: Justicia carnea is a medicinal plant used widely in Nigeria which is reported to have diverse functions, including blood-boosting potential. Aim. The effect of the ethanol extract of Justicea carnea (JC) leaves in phenylhydrazine induced-anemia albino rats on haematological and lipid profile parameters was investigated. METHODS: The experimental animals were randomly grouped into five groups of six rats each – group 1 (non-anemic control), group 2 (anemic control), group 3 (500 mg/kg of JC extract), group 4 (1000 mg/kg of JC extract) and group 5 (DMSO control)...
April 2017: Acta Scientiarum Polonorum. Technologia Alimentaria
https://www.readbyqxmd.com/read/28693591/aphrodisiac-potentials-of-the-ethanol-extract-of-aloe-barbadensis-mill-root-in-male-wistar-rats
#20
Joseph O Erhabor, MacDonald Idu
BACKGROUND: Aloe barbadensis (AB) is a short stemmed succulent medicinal herb that is being used by locals in Nigeria to enhance libido. Therefore this study evaluates the aphrodisiac potential and acute toxicological effect of A. barbadensis (AB) root in male Wistar rats. METHODS: Aphrodisiac potential was determined following the oral administration of graded doses (100, 200 and 400 mg/kg) of ethanol extract of A. barbadensis root. Sildenafil citrate (Viagra) and distilled water served as positive and negative controls respectively...
July 11, 2017: BMC Complementary and Alternative Medicine
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