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https://www.readbyqxmd.com/read/29034599/process-and-impact-of-dialectical-behaviour-therapy-a-systematic-review-of-perceptions-of-clients-with-a-diagnosis-of-borderline-personality-disorder
#1
REVIEW
Hannah Little, Anna Tickle, Roshan das Nair
PURPOSE: To identify, appraise, and synthesize findings from qualitative studies of individuals diagnosed with borderline personality disorder who have experienced dialectical behaviour therapy, to gain further understanding of their perceptions of the process and impact of therapy. METHODS: We conducted a comprehensive systematic search of the literature from several online databases, and appraised them using an adapted version of the Critical Appraisal Skills Programme tool...
October 16, 2017: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/28988193/using-the-esexual-health-clinic-to-access-chlamydia-treatment-and-care-via-the-internet-a-qualitative-interview-study
#2
Catherine R H Aicken, Lorna J Sutcliffe, Jo Gibbs, Laura J Tickle, Kate Hone, Emma M Harding-Esch, Catherine H Mercer, Pam Sonnenberg, S Tariq Sadiq, Claudia S Estcourt, Maryam Shahmanesh
OBJECTIVE: We developed the eSexual Health Clinic (eSHC), an innovative, complex clinical and public health intervention, embedded within a specialist sexual health service. Patients with genital chlamydia access their results online and are offered medical management via an automated online clinical consultation, leading to antibiotic collection from community pharmacy. A telephone helpline, staffed by Sexual Health Advisers, is available to support patients and direct them to conventional services if appropriate...
October 7, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28934614/development-of-mother-infant-interaction-in-tickling-play-the-relationship-between-infants-ticklishness-and-social-behaviors
#3
Konomi Ishijima, Koichi Negayama
This study examined the development of mother-infant tickling interaction and the relationship between infants' ticklishness and social behaviors including infants' looking at mothers' face, mothers' narrative tickling, and mothers' laughter. Twenty-two Japanese infants aged 5 months (n=10, five girls) and 7 months (n=12, four girls) and their mothers were videotaped. Results revealed that the mothers' narrative tickling was more frequent at 7 than at 5 months and the infants' strong ticklishness showed the same tendency...
September 18, 2017: Infant Behavior & Development
https://www.readbyqxmd.com/read/28927396/socioeconomic-disparities-in-orthodontic-treatment-outcomes-and-expenditure-on-orthodontics-in-england-s-state-funded-national-health-service-a-retrospective-observational-study
#4
Juliet Price, William Whittaker, Stephen Birch, Paul Brocklehurst, Martin Tickle
BACKGROUND: This study aimed to assess whether there are potential areas for efficiency improvements in the National Health Service (NHS) orthodontic service in North West England and to assess the socioeconomic status (SES)-related equity of the outcomes achieved by the NHS. METHODS: The study involved a retrospective analysis of 2008-2012 administrative data, and the study population comprised patients aged ≥10 who started NHS primary care orthodontic treatment in North West England in 2008...
September 19, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28902842/the-neuropeptide-nmu-amplifies-ilc2-driven-allergic-lung-inflammation
#5
Antonia Wallrapp, Samantha J Riesenfeld, Patrick R Burkett, Raja-Elie E Abdulnour, Jackson Nyman, Danielle Dionne, Matan Hofree, Michael S Cuoco, Christopher Rodman, Daneyal Farouq, Brian J Haas, Timothy L Tickle, John J Trombetta, Pankaj Baral, Christoph S N Klose, Tanel Mahlakõiv, David Artis, Orit Rozenblatt-Rosen, Isaac M Chiu, Bruce D Levy, Monika S Kowalczyk, Aviv Regev, Vijay K Kuchroo
Type 2 innate lymphoid cells (ILC2s) both contribute to mucosal homeostasis and initiate pathologic inflammation in allergic asthma. However, the signals that direct ILC2s to promote homeostasis versus inflammation are unclear. To identify such molecular cues, we profiled mouse lung-resident ILCs using single-cell RNA sequencing at steady state and after in vivo stimulation with the alarmin cytokines IL-25 and IL-33. ILC2s were transcriptionally heterogeneous after activation, with subpopulations distinguished by expression of proliferative, homeostatic and effector genes...
September 21, 2017: Nature
https://www.readbyqxmd.com/read/28882594/terbinafine-is-a-novel-and-selective-activator-of-the-two-pore-domain-potassium-channel-task3
#6
Paul D Wright, Emma L Veale, David McCoull, David C Tickle, Jonathan M Large, Emma Ococks, Gemma Gothard, Catherine Kettleborough, Alistair Mathie, Jeffrey Jerman
Two-pore domain potassium channels (K2Ps) are characterized by their four transmembrane domain and two-pore topology. They carry background (or leak) potassium current in a variety of cell types. Despite a number of important roles there is currently a lack of pharmacological tools with which to further probe K2P function. We have developed a cell-based thallium flux assay, using baculovirus delivered TASK3 (TWIK-related acid-sensitive K(+) channel 3, KCNK9, K2P9.1) with the aim of identifying novel, selective TASK3 activators...
November 4, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28873769/reconnecting-people-with-dementia-by-using-the-interactive-instrument-crdl
#7
Lisanne Teunissen, Tom Luyten, Luc de Witte
Dementia is a progressive brain disease with a decline in functioning over time. CRDL (pronounced as Cradle) is an interactive instrument, developed to stimulate communication between users through sound and touch. It recognises the intention of the touch (tickle, holding, grabbing, fondling, kneading, and tapping) and will adjust the sound accordingly. This qualitative observational study explores whether this innovative product has the potential to be used in elderly care to create a moment of interaction between the person with dementia and someone else or multiple others...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28811307/an-interview-with-jenny-nichols
#8
Aidan Maartens
Jennifer Nichols is a Principal Investigator at the Cambridge Stem Cell Institute and Department of Physiology, Development and Neuroscience at the University of Cambridge, UK. Her lab works on lineage segregation and the establishment of pluripotency in the mammalian embryo. In 2017 she was awarded the British Society for Developmental Biology's Cheryll Tickle Medal, given to mid-career female scientists with outstanding achievements in developmental biology. We met Jenny in her Cambridge office to talk about pluripotency in vitro and in vivo, the importance of collaboration in her career path, and what playing a musical instrument has in common with research...
August 15, 2017: Development
https://www.readbyqxmd.com/read/28761514/microsurgical-management-of-benign-lesions-interior-to-the-cavernous-sinus-a-case-series
#9
Forhad Hossain Chowdhury, Mohammod Raziul Haque
BACKGROUND: Benign lesion interior to the cavernous sinus (CS) is very rare. OBJECTIVE: In this series we found nonneoplastic lymphatic aggregation and osteoclastoma inside the CS which is very rare and probably not reported in literature. One interesting postoperative complaint of feeling of tickling down of warm water under the skin forehead was found in the patient of inflammatory disease of CS which is not reported in literature. Here we also describe our experiences of microsurgical management of series of benign lesions inside the CS...
July 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28748624/the-relationship-between-coping-style-and-psychological-distress-in-people-with-head-and-neck-cancer-a-systematic-review
#10
REVIEW
Nicolle Morris, Nima Moghaddam, Anna Tickle, Sanchia Biswas
OBJECTIVE: Individuals diagnosed with head and neck cancer (HNC) are at an elevated risk of experiencing psychological distress and a reduced quality of life. The aim of this review was to systematically examine and assess the quality of empirical evidence on the associations between coping mechanisms and psychological distress among people with HNC. METHODS: CINAHL, MEDLINE, PsycINFO, EMBASE and Web of Science were accessed to conduct this review. Studies were included if they used reliable and valid measures to investigate the relationship between coping style and psychological distress...
July 27, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28671715/the-critically-endangered-western-chimpanzee-declines-by-80
#11
Hjalmar S Kühl, Tenekwetche Sop, Elizabeth A Williamson, Roger Mundry, David Brugière, Genevieve Campbell, Heather Cohen, Emmanuel Danquah, Laura Ginn, Ilka Herbinger, Sorrel Jones, Jessica Junker, Rebecca Kormos, Celestin Y Kouakou, Paul K N'Goran, Emma Normand, Kathryn Shutt-Phillips, Alexander Tickle, Elleni Vendras, Adam Welsh, Erin G Wessling, Christophe Boesch
African large mammals are under extreme pressure from unsustainable hunting and habitat loss. Certain traits make large mammals particularly vulnerable. These include late age at first reproduction, long inter-birth intervals, and low population density. Great apes are a prime example of such vulnerability, exhibiting all of these traits. Here we assess the rate of population change for the western chimpanzee, Pan troglodytes verus, over a 24-year period. As a proxy for change in abundance, we used transect nest count data from 20 different sites archived in the IUCN SSC A...
September 2017: American Journal of Primatology
https://www.readbyqxmd.com/read/28652793/evaluation-of-a-novel-very-high-sun-protection-factor-moisturizer-in-adults-with-rosacea-prone-sensitive-skin
#12
Mathieu Grivet-Seyve, Francine Santoro, Nadège Lachmann
BACKGROUND/OBJECTIVE: Rosacea-prone sensitive skin requires high sun-protection factor (SPF) moisturizers. This study evaluated Daylong Extreme SPF 50+ lotion, a novel cream containing five ultraviolet filters, two emollients, and three skin conditioners. SUBJECTS AND METHODS: This was an open-label, single-center study. On day 1, before treatment, subjects answered a questionnaire on their skin conditions and sunscreen habits, and both subjects and dermatologist evaluated skin status...
2017: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/28628536/forging-alliances-in-interdisciplinary-rehabilitation-research-fairr-a-logic-model
#13
Simone V Gill, Mary A Khetani, Leanne Yinusa-Nyahkoon, Beth McManus, Paula M Gardiner, Linda Tickle-Degnen
In a patient-centered care era, rehabilitation can benefit from researcher-clinician collaboration to effectively and efficiently produce the interdisciplinary science that is needed to improve patient-centered outcomes. The authors propose the use of the Forging Alliances in Interdisciplinary Rehabilitation Research (FAIRR) logic model to provide guidance to rehabilitation scientists and clinicians who are committed to growing their involvement in interdisciplinary rehabilitation research. We describe the importance and key characteristics of the FAIRR model for conducting interdisciplinary rehabilitation research...
July 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28625869/an-historical-perspective-on-the-pioneering-experiments-of-john-saunders
#14
REVIEW
Cheryll Tickle
John Saunders was a highly skilled embryologist who pioneered the study of limb development. His studies on chick embryos provided the fundamental framework for understanding how vertebrate limbs develop. This framework inspired generations of scientists and formed the bridge from experimental embryology to molecular mechanisms. Saunders investigated how feathers become organized into tracts in the skin of the chick wing and also identified regions of programmed cell death. He discovered that a region of thickened ectoderm that rims the chick wing bud - the apical ectodermal ridge - is required for outgrowth and the laying down of structures along the proximo-distal axis (long axis) of the wing, identified the zone of polarizing activity (ZPA; polarizing region) that controls development across the anteroposterior axis ("thumb to little finger "axis) and contributed to uncovering the importance of the ectoderm in development of structures along the dorso-ventral axis ( "back of hand to palm" axis)...
September 15, 2017: Developmental Biology
https://www.readbyqxmd.com/read/28573841/productive-efficiency-and-its-determinants-in-the-community-dental-service-in-the-north-west-of-england
#15
H Hill, S Birch, M Tickle, R McDonald, P Brocklehurst
OBJECTIVES: To assess the efficiency of service provision in the Community Dental Services and its determinants in the North-West of England. SETTING AND SAMPLE: 40 Community Dental Services sites operating across the North-West of England. BASIC RESEARCH DESIGN: A data envelopment analysis was undertaken of inputs (number of surgeries, hours worked by dental officers, therapists, hygienists and others) and outputs (treatments delivered, number of courses of treatment and patients seen) of the Community Dental Services to produce relative efficiency ratings by health authority...
June 2017: Community Dental Health
https://www.readbyqxmd.com/read/28571506/longitudinal-study-of-caries-development-from-childhood-to-adolescence
#16
E Hall-Scullin, H Whitehead, K Milsom, M Tickle, T-L Su, T Walsh
The World Health Organization (WHO) stated that globally, dental caries is the most important oral condition. To develop effective prevention strategies requires an understanding of how this condition develops and progresses over time, but there are few longitudinal studies of caries onset and progression in children. The aim of the study was to establish the pattern of caries development from childhood into adolescence and to explore the role of potential risk factors (age, sex, ethnicity, and social deprivation)...
July 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28565899/post-infectious-persistent-cough-pathogenesis-and-therapeutic-options
#17
Carlo Capristo, Giovanni A Rossi
Post-infectious cough is a common symptom associated with common colds and/or upper respiratory tract infection. This cough is expected to last for only for few days and resolve spontaneously, whilst when persists for longer than three weeks is defined "persistent" and is associated tickling or an irritating sensation in the throat which often leads to paroxysms of coughing. Persistent post-infectious cough can cause morbidity since it may interfere with usual living. Despite the recent advances in understanding the mechanisms that regulate cough, in physiological and pathological conditions, current therapeutic options for post-infectious cough are little or only moderately effective...
May 31, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/28538821/sensory-symptoms-in-patients-undergoing-thyroidectomy
#18
COMPARATIVE STUDY
Lillian Fernandes de Araújo, Leonardo Wanderley Lopes, Priscila Oliveira Costa Silva, Victor Jose Ferreira Perrusi, Vívian Lisboa de Lucena Farias, Elma Heitmann Mares Azevedo
Purpose: To verify the occurrence of sensory symptoms in thyroidectomy patients pre- and post-operatively. Methods: This is a prospective, quantitative, descriptive study conducted with a sample of twelve patients undergoing thyroidectomy. The participants underwent visual laryngeal examination and responded to the Upper Aerodigestive Symptoms (UADS) and Vocal Tract Discomfort Scale (VTDS) questionnaires before and after the surgery. Results: There was higher occurrence of vocal fatigue, hoarseness, pharyngeal bolus, dry throat, and throat clearing preoperatively, whereas higher occurrence of hoarseness, vocal fatigue, cough, and pharyngeal bolus was observed postoperatively for the UADS...
May 15, 2017: CoDAS
https://www.readbyqxmd.com/read/28521109/cost-effectiveness-of-caries-prevention-in-practice-a-randomized-controlled-trial
#19
RANDOMIZED CONTROLLED TRIAL
C O'Neill, H V Worthington, M Donaldson, S Birch, S Noble, S Killough, L Murphy, M Greer, J Brodison, R Verghis, M Tickle
A 2-arm parallel-group randomized controlled trial measured the cost-effectiveness of caries prevention in caries-free children aged 2 to 3 y attending general practice. The setting was 22 dental practices in Northern Ireland. Participants were centrally randomized into intervention (22,600 ppm fluoride varnish, toothbrush, a 50-mL tube of 1,450 ppm fluoride toothpaste, and standardized prevention advice) and control (advice only), both provided at 6-monthly intervals during a 3-y follow-up. The primary outcome measure was conversion from caries-free to caries-active states assessed by calibrated and blinded examiners; secondary outcome measures included decayed, missing, or filled teeth surfaces (dmfs); pain; and extraction...
July 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28509865/detecting-and-classifying-human-touches-in-a-social-robot-through-acoustic-sensing-and-machine-learning
#20
Fernando Alonso-Martín, Juan José Gamboa-Montero, José Carlos Castillo, Álvaro Castro-González, Miguel Ángel Salichs
An important aspect in Human-Robot Interaction is responding to different kinds of touch stimuli. To date, several technologies have been explored to determine how a touch is perceived by a social robot, usually placing a large number of sensors throughout the robot's shell. In this work, we introduce a novel approach, where the audio acquired from contact microphones located in the robot's shell is processed using machine learning techniques to distinguish between different types of touches. The system is able to determine when the robot is touched (touch detection), and to ascertain the kind of touch performed among a set of possibilities: stroke, tap, slap, and tickle (touch classification)...
May 16, 2017: Sensors
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