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umbilical artery S/D ratio

Guofang Shen, Yajuan Huang, Lixin Jiang, Jinghong Gu, Yaxin Wang, Bing Hu
The objective was to assess the sensitivities and accuracies of Doppler ultrasound parameters in the second and third trimester of hypertensive pregnancies in determining perinatal outcomes. 1,054 pregnancies were retrospectively categorized into three groups (healthy pregnancies (HP, n = 988), pregnancies of hypertensive women (HypP, n = 30) and high-risk hypertension pregnancies (HRHypP, n = 36), depending on gestational hypertension as well as fetal birth weights and pregnancy outcomes. Systolic/diastolic ratio (S/D), resistance index (RI), pulsatility index (PI) of the bilateral uterine artery, umbilical artery and vein as well as venous flow velocity data were monitored by Doppler ultrasound...
January 16, 2017: Scientific Reports
Alison Stalzer, Dara Seybold, Deena Hossino, Mike Broce, Byron Calhoun
OBJECTIVE: The purpose of this study was to investigate associations between Doppler measurements and adverse outcomes in an obstetric population with high tobacco use. METHODS: This retrospective study included patients with Doppler data (umbilical systolic/diastolic velocity ratios (S/D), uterine S/D, uterine left/right ratio index (RI)). Receiver operator characteristic curve analysis determined cut-off elevated Doppler indices. Stepwise logistic regression was used to predict adverse outcomes...
November 9, 2016: Reproductive Toxicology
Oluwagbemiga Oluwole Ayoola, Peter Bulus, Olabisi Morebisi Loto, Bukunmi Michael Idowu
AIM: To determine the Doppler indices of the umbilical arteries in normal singleton pregnancy with a view to generating local reference ranges. METHODS: In this prospective, cross-sectional study, 400 pregnant women at 15-39 weeks' gestational age, with estimated fetal weight within the 10th and 90th percentile, no fetal malformation(s), and without any history of maternal medical disease, were recruited. Umbilical arteries were assessed on ultrasound, with the subjects in the supine position...
December 2016: Journal of Obstetrics and Gynaecology Research
P G Blanco, R Vercellini, A Rube, R Rodríguez, D O Arias, C Gobello
The aim of this study was to describe resistance index (RI) and systolic/diastolic ratio (S/D ratio) of uterine and umbilical arteries in an experimental model of abnormal pregnancy in felids. On days 30 to 35 (32 ± 2.9) after mating, 20 domestic short-hair pregnant queens were randomly assigned to one of the following treatment groups: a treated group (TG; n = 8), which received 10 mg/kg of aglepristone subcutaneously twice, 24 hours apart, and a control nontreated group (CG; n = 12). M-mode and Doppler ultrasonographic evaluations were performed at the initiation of the treatment (Day 0) and then every other day during 8 days...
December 2016: Theriogenology
Fang Liu, Yong Liu, Ya-Ping Lai, Xiao-Ning Gu, Dong-Mei Liu, Min Yang
BACKGROUND: The offspring of women with gestational diabetes mellitus (GDM) are prone to macrosomia. However, birth weight is difficult to be correctly estimated by ultrasound because of fetal asymmetric growth characteristics. This study aimed to investigate the correlations between fetal hemodynamics, fetal growth indices in late pregnancy, and birth weight in GDM. METHODS: A total of 147 women with GDM and 124 normal controls (NC) were enrolled in this study...
September 5, 2016: Chinese Medical Journal
Ertugrul Karahanoglu, Orhan Altinboga, Funda Akpinar, Erhan Demirdag, Safak Ozdemirci, Aysegul Akyol, Serdar Yalvac
AIM: Our aim is to evaluate the effect of nifedipine on fetoplacental hemodynamic parameters. METHODS: A retrospective study was conducted at a tertiary center with 30 patients for whom nifedipine treatment was used as a tocolytic therapy for preterm labor. Initiation of this treatment was at 31.6±2.5 weeks of gestation. We combined the pulse Doppler imaging parameters with grayscale imaging via the Bernoulli theorem, which is called the "continuity equation", to get the fetoplacental perfusion (FPP)...
January 1, 2017: Journal of Perinatal Medicine
Rehana Najam, Sarika Gupta, Shalini
OBJECTIVE: To assess the predictive value of cerebroplacental ratio (i.e., S/D ratio of middle cerebral artery to S/D ratio of Umbilical artery) in detection of perinatal outcome in high-risk pregnancies. MATERIAL AND METHOD: This retrospective study was conducted on 150 patients between 28 and 40 weeks of gestation (25 low risk and 125 high risk) who attended OPD and indoor wards of Teerthanker Mahaveer medical college and research center, Moradabad. All patients had serial color Doppler ultrasounds done after taking informed consent which was repeated at 2 weeks interval, and data were collected with regard to perinatal outcome...
August 2016: Journal of Obstetrics and Gynaecology of India
Ahmed M Maged, Ahmed M T Hashem, Sherine H Gad Allah, Mohamed El Mahy, Walaa A I Mostafa, Amal Kotb
UNLABELLED: SYNOPSIS IV MgSO4 administration in women with severe preeclampsia resulted in a decrease in umbilical artery, uterine artery, and fetal middle cerebral artery Doppler indices. OBJECTIVE: To evaluate Doppler parameters of the umbilical artery (UmA), uterine artery (UA), and fetal middle cerebral artery (MCA) before and after MgSO4 administration in women with severe preeclampsia. METHODS: A case control study included 100 pregnant women with severe preeclampsia...
2016: Hypertension in Pregnancy
Guomin Hu, Rui Guan, Li Li
OBJECTIVE: We investigated the correlations of nucleated red blood cell (NRBC) counts with hypertensive disorders in pregnancy (HDP) and fetal umbilical blood flow velocity. MATERIALS AND METHODS: We recruited 282 patients with HDP as experimental group including 107 with mild pre-eclampsia (A1 group), 100 with severe pre-eclampsia (A2 group) and 75 with eclampsia (A3 group), and 215 normal pregnant women as control group. Maternal peripheral venous blood was collected and isolated cells were stained with Wright-Giemsa...
February 2016: American Journal of the Medical Sciences
Zoya Gordon, Lilia Glaubach, David Elad, Uri Zaretsky, Ariel J Jaffa
OBJECTIVES: The purpose of this study was to develop an ex vivo placental perfusion model to assess changes in the umbilical artery systolic-to-diastolic (S/D) ratio due to progressive occlusion of the placental arterial system. METHODS: Ex vivo human placentas were connected to a computerized pulse duplicator mimicking pulsatile flow from the fetal heart. Doppler sonographic measurements were conducted on the umbilical and chorionic arteries of 25 mature placentas...
March 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Atilla Karateke, Mustafa Kaplanoglu, Fazil Avci, Raziye Keskin Kurt, Ali Baloglu
OBJECTIVE: To evaluate the effects of Ramadan fasting on fetal development and outcomes of pregnancy. METHODS: We performed this study in Antakya State Hospital of Obstetrics and Child Care, between 28 June 2014 and 27 July 2014 (during the month of Ramadan). A total of two hundred forty healthy pregnant women who were fasting during Ramadan, were included in the groups. The three groups were divided according to the trimesters. The each group was consisted of 40 healthy pregnant women with fasting and 40 healthy pregnant women without fasting...
November 2015: Pakistan Journal of Medical Sciences Quarterly
Fangui Zhao, Qiuying Geng, Fanbin Kong, Yan Ning
The perinatal outcomes of pregnancies with nuchal cord (NC) are uncertain and reports disagree about the incidence of cesarean section due to NC. Variable tightness of the NC may be a contributor to this controversy. The study was to examine whether the tightness of NC affect fetal intrauterine distress by determining valuable ultrasonic indicators. Total 149 singleton pregnancies between 36 and 41 weeks without pregnancy complications were recruited. The pregnant women, whose fetuses have NC, formed the study group and the others made up the control group...
2015: International Journal of Clinical and Experimental Medicine
Chong-xin Tong, Xiao-fen Xing, Shu-hua Qiao, Lin Liu, Ling Shan
OBJECTIVE: To observe the effect of low molecular weight heparin calcium (LMWHC) combined Compound Danshen Injection (DI) on nephrotic syndrome patients with early onset severe preeclampsia. METHODS: Totally 80 nephrotic syndrome patients with early onset severe pre-eclampsia were randomly assigned to four groups voluntarily, i.e., Group A (22 cases, treated by magnesium sulfate), B (19 cases, treated by magnesium sulfate plus LMWHC), C (21 cases, magnesium sulfate plus DI), D (18 cases, magnesium sulfate plus LMWHC and DI)...
August 2015: Chinese Journal of Integrated Traditional and Western Medicine
Ting Yuan, Ting Zhang, Zhen Han
BACKGROUND: Hypertensive disorders complicating pregnancy (HDCP) continues to be a leading cause of maternal and neonatal mortality and morbidity. The clinical value of placental three-dimensional power Doppler (3DPD) in assessing HDCP requires further confirmation. The research was developed to assess changes of placental vascularity in HDCP using 3DPD and to investigate the placental vascularity in small for gestational age (SGA) compared with not-SGA in patients with HDCP. METHODS: There were 126 normotensive and 128 hypertensive pregnant women included in this prospective case-control study from March 2011 to March 2013...
October 5, 2015: BMC Pregnancy and Childbirth
S J Eschbach, L S T M Boons, R Wolterbeek, J M Middeldorp, F J C M Klumper, E Lopriore, D Oepkes, M C Haak
OBJECTIVE: Single fetal demise (SFD) occurs in up to 20% of monochorionic pregnancies treated with laser coagulation for twin-twin transfusion syndrome (TTTS). We aimed to determine the independent factors associated with SFD to improve outcome in the care of TTTS pregnancies in the future. METHODS: This was a case-control study on twin pregnancies treated for TTTS between 2007 and 2013. Data on ultrasound, laser surgery and outcome were retrieved from our monochorionic twin database...
March 2016: Ultrasound in Obstetrics & Gynecology
D A Woelkers, R Ghashghaei, K Klisser, T Archer
INTRODUCTION: Maternal vascular adaptation to pregnancy involves the coordinated augmentation of both systemic and uteroplacental circulations, with the concomitant development of a new fetoplacental circuit. Disturbances of maternal hemodynamic adaptation in early pregnancy are often associated with compromise in the other circulations, although the assessment of maternal vascular function by conventional means is cumbersome and expensive. OBJECTIVES: We sought to assess maternal hemodynamic function with a noninvasive cardiographic monitor, and to correlate the findings to both uteroplacental and fetoplacental vascular resistance...
July 2012: Pregnancy Hypertension
D A Woelkers, R Ghashghaei, K Klisser, T Archer
INTRODUCTION: Placental Growth Factor (PlGF) is an angiogenic and vasoregulatory peptide member of the vascular endothelial growth factor family. Reduction of free, circulating PlGF is associated with preeclampsia and fetal growth restriction, and precedes the clinical manifestations of disease by several weeks. It is not known whether aberrant PlGF is related for alterations in endothelial vascular function that cause or exacerbate the placental syndromes of pregnancy. OBJECTIVES: We sought to determine if mid-pregnancy PlGF was related to, and possibly mediating, measures of maternal, fetal, or uterine hemodynamic function in women at risk for placenta-mediated complications of pregnancy...
July 2012: Pregnancy Hypertension
Johanes C Mose
Pre-eclampsia is associated with significant maternal and fetal morbidity and mortality worldwide. Pregnancy complicated by preeclampsia and/or by fetal growth restriction are reported to have inadequate maternal vascular responses to placentation. This defective vascular response was due to the failure of second wave of endovascular trophoblast migration leading to both a reduced amount and depth of trophoblast invasion of myometrium followed by the development of placental hypoxia and ischemia that can be measured biophysically by means of Doppler Ultrasound...
July 2014: Pregnancy Hypertension
Seçil Kurtulmuş, Esra Bahar Gür, Deniz Öztekin, Ebru Şahin Güleç, Duygu Okyay, İbrahim Gülhan
OBJECTIVE: The aim of this study was to evaluate changes in fetal cardiac and peripheral circulation in pregnancies complicated with intrahepatic cholestasis. MATERIAL AND METHODS: The Doppler examination results of 22 pregnant subjects complicated with intrahepatic cholestasis of pregnancy (ICP) and 44 healthy controls were compared. The parameters of fetal cardiac circulation were pulmonary artery and aortic (Ao) peak systolic velocity (PSV), pulmonary vein (Pv), peak velocity index (PVI) and pulsatility index (PI), mitral valve (MV) and tricuspid valve (TV), early diastole (E)- and atrial contraction (A)-wave peak velocity ratio (E/A), and isthmus aortic peak systolic velocity (IAo PSV)...
2015: Journal of the Turkish German Gynecological Association
Teena Nagar, Deepak Sharma, Mukesh Choudhary, Shusheela Khoiwal, Rajendra Prasad Nagar, Aakash Pandita
AIM: To study the role of Doppler imaging in prediction of high-risk pregnancies and their outcomes. METHODS AND MATERIAL: This prospective study in a setup of tertiary-level care center includes 500 high-risk pregnant women from rural and urban sectors and evaluates the predictive values of various Doppler indices. RESULTS: Out of 500 patients, 110 patients had abnormal Doppler among them, 70 patients had abnormal uterine artery Doppler, and 50 patients had abnormal umbilical artery Doppler flow indices...
2015: Clinical Medicine Insights. Reproductive Health
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