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Esophageal resection

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https://www.readbyqxmd.com/read/29774930/-advertent-problems-about-gastric-stump-cancer-surgery
#1
Han Liang
Due to different disease background of gastric stump cancer(GSC) patients (benign or malignant lesion, reconstruction of digestive tract, etc.), the GSC surgical procedure and the difficulty of lymphadenectomy are also different. The extent of radical lymphadenectomy for gastric stump cancer should extend beyond D2 lymphadenectomy, according to the different backgrounds of initial disease, reconstructions, and tumor location. A lymphadenectomy should include the lymph nodes in anterior (No.17) and posterior (No...
May 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29768079/the-spectrum-of-surgical-remediation-of-transoral-incisionless-fundoplication-related-failures
#2
Ruchir Puri, C Daniel Smith, Steven P Bowers
AIM: To evaluate outcomes of surgical remediation for symptomatic or anatomic failure after a transoral incisionless fundoplication (TIF). METHODS: This retrospective study was performed on 11 patients who underwent a remedial operation following TIF failure between June 2011 and September 2016 at the Mayo Clinic in Florida for persistent foregut symptoms. Upper gastrointestinal workup characterized 1 patient as having normal post-TIF anatomy and 10 as having anatomic failure...
May 16, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29765221/surgical-treatment-of-an-esophageal-bronchogenic-cyst-with-massive-upper-digestive-tract-hematoma-without-esophagectomy-a-case-report-and-the-review-of-the-literature
#3
Yuanjun Cheng, Donglai Chen, Li Shi, Wentao Yang, Yonghua Sang, Shanzhou Duan, Yongbing Chen
Esophageal bronchogenic cysts are extremely rare. Here we report a case of massive upper digestive tract hematoma and bronchogenic cyst mimicking aortic dissection that was safely removed without esophagectomy. A 30-year-old man was referred to our hospital for the treatment of a mediastinal cystic tumor located in the submucosa of the distal esophagus. His chief complaints were dysphagia > 1 week and severe persistent upper abdominal pain mimicking aortic dissection with constant vomiting for 1 day after gastroscopy examination...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29764483/impact-of-type-2-diabetes-mellitus-on-short-term-and-long-term-outcomes-of-patients-with-esophageal-squamous-cell-cancer-undergoing-resection-a-propensity-score-analysis
#4
Wang Yao, Yuqi Meng, Mingjian Lu, Wenzhe Fan, Jinhua Huang, Jiaping Li, Zhihua Zhu
BACKGROUND: The association between type 2 diabetes mellitus (T2DM) and the risk of esophageal cancer remains unclear. The present study aimed to evaluate the impact of T2DM on short-term outcomes and long-term survival in patients with esophageal squamous cell cancer (ESCC). METHODS: The present retrospective study included 862 patients diagnosed with ESCC between January 2001 and December 2010. Among them, 280 patients had T2DM. A 1:1 propensity score-matched cohort consisting of 280 patients with and 280 without T2DM was selected from the 862 patients...
April 27, 2018: Cancer communications
https://www.readbyqxmd.com/read/29761863/surgical-treatment-of-esophageal-cancer-in-the-era-of-multimodality-management
#5
REVIEW
Alicia S Borggreve, B Feike Kingma, Serg A Domrachev, Mikhail A Koshkin, Jelle P Ruurda, Richard van Hillegersberg, Flavio R Takeda, Lucas Goense
Over the last decades, the treatment of resectable esophageal cancer has evolved into a multidisciplinary process in which all players are essential for treatment to be successful. Medical oncologists and radiation oncologists have been increasingly involved since the implementation of neoadjuvant therapy, which has been shown to improve survival. Although esophagectomy is still considered the cornerstone of curative treatment for locally advanced esophageal cancer, it remains associated with considerable postoperative morbidity, despite promising results of minimally invasive techniques...
May 15, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29757564/-re-operation-treatment-in-uremic-patients-complicated-with-persistent-secondary-hyperparathyroidism-after-parathyroidectomy-with-autotransplantation
#6
Shao Jun Bo, Xian Fa Xu, Chuan Ya Qiu, Tian Tian Wang, Yu Dong Ning, Hong Yue Li
Objective: To analyze the clinical profile and therapeutic effect of re-operation treatment in uremic patients complicated with persistent secondary hyperparathyroidism(SHPT)after parathyroidectomy with autotransplantation. Method: Twelve persistent SHPT patients who were treated with reoperation of paramyroidectomy(PTX)were enrolled in this study during the period from Jan 2014 to Jul 2017 in our hospital.We evaluated the location of the remaining parathyroid glands by ultrasonography,dual-phase 99 Tcm-sestamibi scintigraphy,CT and MR imaging of the neck before the operation...
January 20, 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29752721/can-endoscopic-resection-for-barrett-s-dysplasia-and-early-cancer-be-curative
#7
REVIEW
Shai Friedland, George Triadafilopoulos
Effective endoscopic treatments for dysplasia and early (intramucosal) cancer, together with expanded and rigorous screening programs to detect Barrett's esophagus, could help reverse the increase in the incidence of esophageal cancer and reduce esophageal cancer-related mortality. In this review, we discuss the long-term outcomes for mucosal resection for dysplasia and early cancer and compares them to esophagectomy as the standard of care choice. Eendoscopic resection for Barrett's dysplasia and early cancer can be curative but only when the lesion can be classified as: Paris type I (polypoid); Paris IIa (slightly elevated); Paris IIb (flat); Paris IIc (slightly depressed); histological grades G1 and G2; high-grade dysplasia...
May 11, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29752605/influence-of-incomplete-neoadjuvant-chemotherapy-on-esophageal-carcinoma
#8
Yushi Fujiwara, Shigeru Lee, Satoru Kishida, Ryoya Hashiba, Ken Gyobu, Ryoko Naka, Masaki Nishiyama, Toshio Ihara, Masashi Takemura, Harushi Osugi
BACKGROUND: Neoadjuvant chemotherapy (NAC) involving two cycles of cisplatin plus fluorouracil is recommended in Japan as a standard treatment for resectable, locally advanced esophageal squamous cell carcinoma (ESCC). We have encountered patients who were administered incomplete chemotherapy because of adverse events or the patient's refusal of treatment. Here, we retrospectively investigated the influence on perioperative outcomes and long-term prognosis of patients with ESCC who underwent complete (two cycles) or incomplete (one cycle) NAC...
May 11, 2018: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29750982/technical-feasibility-and-oncological-safety-of-diagnostic-endoscopic-resection-for-superficial-esophageal-cancer
#9
Masashi Takeuchi, Koichi Suda, Yasuo Hamamoto, Motohiko Kato, Shuhei Mayanagi, Kayo Yoshida, Kazumasa Fukuda, Rieko Nakamura, Norihito Wada, Hirofumi Kawakubo, Hiroya Takeuchi, Naohisa Yahagi, Yuko Kitagawa
BACKGROUND: Active use of endoscopic resection (ER) for cM3-SM2 esophageal cancer may enable sufficient extent of esophageal resection and help determine the need for lymph node dissection based on histopathological findings. However, ER preceding esophagectomy may have an adverse impact on outcomes. This study was designed to determine the technical feasibility and oncological safety of diagnostic ER. METHODS: A single-institution retrospective cohort study was performed between July 2008 and June 2014...
May 8, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29749321/prevalence-of-the-integration-status-for-human-papillomavirus-16-in-esophageal-carcinoma-samples
#10
Shuying Li, Haie Shen, Ji Li, Xiaoli Hou, Ke Zhang, Jintao Li
BACKGROUND/AIMS: To investigate the etiology of esophageal cancer (EC) related with human papillomavirus (HPV) infection. MATERIALS AND METHODS: Fresh surgically resected tissue samples and clinical information were obtained from 189 patients. Genomic DNA was extracted, and HPV was detected using polymerase chain reaction (PCR) with HPV L1 gene primers of MY09/11; HPV16 was detected using HPV16 E6 type-specific primer sets. Copies of HPV16 E2, E6, and the human housekeeping gene β-actin were tested using quantitative PCR to analyze the relationship between HPV16 integration and esophageal squamous cell carcinoma and the relationship between the HPV16 integration status and clinical information of patients...
March 2018: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/29740725/a-case-of-mixed-adenoneuroendocrine-carcinoma-manec-arising-in-barrett-s-esophagus-literature-and-review
#11
Tetsuro Kawazoe, Hiroshi Saeki, Keitaro Edahiro, Shotaro Korehisa, Daisuke Taniguchi, Kensuke Kudou, Ryota Nakanishi, Nobuhide Kubo, Koji Ando, Yuichiro Nakashima, Eiji Oki, Minako Fujiwara, Yoshinao Oda, Yoshihiko Maehara
BACKGROUND: Mixed adenoneuroendocrine carcinoma (MANEC) is defined as a neoplasm composed of both exocrine and endocrine carcinomas, each comprising at least 30% of the tumor. MANEC can occur in various organs of the gastrointestinal tract, including the esophagus, stomach, and colon. We herein provide the first case report of surgically resected MANEC arising in Barrett's esophagus (BE). CASE PRESENTATION: A 70-year-old man presenting with abdominal pain was referred to our hospital...
May 8, 2018: Surgical Case Reports
https://www.readbyqxmd.com/read/29739952/translational-study-identifies-xpf-and-mus81-as-predictive-biomarkers-for-oxaliplatin-based-peri-operative-chemotherapy-in-patients-with-esophageal-adenocarcinoma
#12
T P MacGregor, R Carter, R S Gillies, J M Findlay, C Kartsonaki, F Castro-Giner, N Sahgal, L M Wang, R Chetty, N D Maynard, J B Cazier, F Buffa, P J McHugh, I Tomlinson, M R Middleton, R A Sharma
Oxaliplatin-based chemotherapy is used to treat patients with esophageal adenocarcinoma (EAC), but no biomarkers are currently available for patient selection. We performed a prospective, clinical trial to identify potential biomarkers associated with clinical outcomes. Tumor tissue was obtained from 38 patients with resectable EAC before and after 2 cycles of oxaliplatin-fluorouracil chemotherapy. Pre-treatment mRNA expression of 280 DNA repair (DNAR) genes was tested for association with histopathological regression at surgery, disease-free survival (DFS) and overall survival (OS)...
May 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29739048/sirtuin-2-sirt2-expression-predicts-lymph-node-metastasis-and-poor-overall-survival-of-patients-with-esophageal-squamous-cell-carcinoma
#13
Li Yan, Xuemei Zhan, Zhongyao Jia, Lili Liu, Ning Jin
BACKGROUND: Altered expression of Sirtuin 2 (Sirt2) was associated with cancer development and progression. This study further assessed the association of Sirt2 expression with clinicopathological data and prognosis of patients with esophageal squamous cell carcinoma (ESCC) after postoperative concurrent chemoradiotherapy. METHODS: Tissue specimens from 95 ESCC patients were collected for immunohistochemical analysis of Sirt2 expression, which was used to determine association with patient clinicopathological and survival data...
May 1, 2018: Clinical Laboratory
https://www.readbyqxmd.com/read/29738757/centralizing-esophagectomy-to-improve-outcomes-and-enhance-clinical-research-invited-expert-review
#14
REVIEW
Andrew C Chang
Since the 1970s studies have demonstrated a strong association between operative volume and outcomes such as mortality and complications particularly for complex cancer resections such as esophagectomy. The denouement has been to suggest that this operation should be directed towards specialized centers of esophageal cancer care, with operative volume thresholds being the primary basis for evidence-based hospital referral. In this article, early efforts to centralize esophagectomy as reported from other countries such as England, Canada and the Netherlands, as well as the potential impact on access to care from instituting such policies in the United States are reviewed...
May 5, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29737225/esophageal-pyogenic-granuloma-a-case-report-and-review-of-the-literature
#15
David A Suarez-Zamora, Paula A Rodriguez-Urrego, Jaime Solano-Mariño, Fernando Sierra-Arango, Mauricio A Palau-Lazaro
Pyogenic granuloma (PG) is a capillary hemangioma mainly found in the skin and oral mucosa, but rarely described in the esophagus. We report the case of a 66-year-old man who consulted for retrosternal pain. Endoscopic studies showed a 28-mm polypoid mass located at the distal esophageal mucosa. The patient underwent endoscopic resection, and the histopathological examination showed a neoplastic proliferation of small blood vessels growing in a lobular architecture, with edematous stroma and prominent inflammatory infiltrate...
May 1, 2018: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29736832/autologous-flap-transfer-for-esophageal-stricture-prevention-after-endoscopic-submucosal-dissection-in-a-porcine-model
#16
Airong Tang, Cuiyun Ma, Pei Deng, Hanqing Zhang, Yang Xu, Min Min, Yan Liu
BACKGROUND: Esophageal stricture caused by endoscopic submucosal dissection for a mucosal defect that covers more than three quarters of the circumference of the esophagus has a high incidence. To date, no method for preventing such strictures has been widely recognized as effective in clinical practice. AIMS: We examined whether esophageal stricture caused by circumferential endoscopic submucosal dissection could be prevented by autologous flap transfer. METHODS: Six pigs (N = 6) underwent circumferential esophageal endoscopic submucosal dissection under general anesthesia...
May 8, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29733523/pattern-and-risk-factors-for-distant-metastases-in-gastrointestinal-neuroendocrine-neoplasms-a-population-based-study
#17
Wen Cai, Yinuo Tan, Weiting Ge, Kefeng Ding, Hanguang Hu
An increased incidence of gastrointestinal neuroendocrine neoplasms (GI-NENs) has been reported worldwide, and metastasis is the leading cause of GI-NEN-related death. Studies of different metastatic patterns in patients with different primary sites are limited. A population-based retrospective cohort study was conducted with the Surveillance, Epidemiology, and End Results (SEER) database. Patients with a GI-NEN diagnosis between 2010 and 2014 were included. All statistical analyses were performed using Intercooled Stata 12...
May 7, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29733013/neoadjuvant-radiochemotherapy-for-patients-with-locally-advanced-esophagogastric-junction-adenocarcinoma
#18
Cristian Daniel Marica, Rodica Birlă, Raluca Marica, Eugenia Panaitescu, Silviu Constantinoiu
SCOPE: neoadjuvant RCT influence on early and long term postoperative outcomes in patients with locally advanced esophagogastric junction adenocarcinomas. MATERIALS AND METHOD: Sixty two patients with locally advanced esophagogastric junction adenocarcinomas were treated at the Center of Excellence in Esophageal Surgery at St. Mary Hospital between 2010-2017. According to the Siewert classification, the group comprised of type I - 11 patients, type II - 18 patients and type III - 33 patients...
March 2018: Chirurgia
https://www.readbyqxmd.com/read/29733012/robotic-approach-in-benign-and-malignant-esophageal-tumors-a-preliminary-seven-case-series
#19
Victor Tomulescu, Codrut Stanescu, Cristian Blajut, Loredana Barbulescu, Gabriela Droc, Vlad Herlea, Irinel Popescu
Esophageal surgery has been recognized as very challenging for surgeons and risky for patients. Thoracoscopic approach have proved its benefit in esophageal surgery but has some drawbacks as tremor and limited degrees of freedom, contra-intuitive movements and fulcrum effect of the surgical tools. Robotic technology has been developed with the intent to overcome these limitations of the standard laparoscopy or thoracoscopy. These benefits of robotic procedure are most advantageous when operating in remote areas difficult to reach as in esophageal surgery...
March 2018: Chirurgia
https://www.readbyqxmd.com/read/29731124/corrigendum-to-endoscopic-resection-with-adjuvant-chemo-radiotherapy-for-superficial-esophageal-squamous-cell-carcinoma-a-critical-review-crit-rev-oncol-hematol-124-april-2018-61-65
#20
Tsz Yeung Kam, Melpomeni Kountouri, Arnaud Roth, Jean-Louis Frossard, Olivier Huber, Stefan Mönig, Thomas Zilli
No abstract text is available yet for this article.
May 3, 2018: Critical Reviews in Oncology/hematology
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