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https://www.readbyqxmd.com/read/28214544/can-functional-magnetic-resonance-imaging-studies-help-with-the-optimization-of-health-messaging-for-lifestyle-behavior-change-a-systematic-review
#1
REVIEW
Maxine E Whelan, Paul S Morgan, Lauren B Sherar, Mark W Orme, Dale W Esliger
Unhealthy behaviors, including smoking, poor nutrition, excessive alcohol consumption, physical inactivity and sedentary lifestyles, are global risk factors for non-communicable diseases and premature death. Functional magnetic resonance imaging (fMRI) offers a unique approach to optimize health messages by examining how the brain responds to information relating to health. Our aim was to systematically review fMRI studies that have investigated variations in brain activation in response to health messages relating to (i) smoking; (ii) alcohol consumption; (iii) physical activity; (iv) diet; and (v) sedentary behavior...
February 15, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28212984/hiv-1-vpr-disrupts-mitochondria-axonal-transport-and-accelerates-neuronal-aging
#2
Ying Wang, Maryline Santerre, Italo Tempera, Kayla Martin, Ruma Mukerjee, Bassel E Sawaya
Disruption of mitochondria axonal transport, essential for the maintenance of synaptic and neuronal integrity and function, has been identified in neurodegenerative diseases. Whether HIV-1 viral proteins affect mitochondria axonal transport is unknown, albeit HIV-associated neurocognitive disorders occur in around half of the patients living with HIV. Therefore, we sought to examine the effect of HIV-1 viral protein R (Vpr) on mitochondria axonal transport. Using mice primary neuronal cultures, we demonstrated that 4-day Vpr treatment reduced the ratio of moving mitochondria associated with (i) less energy (ATP) supply, (ii) reduction in Miro-1 and (iii) increase of α-synuclein which led to loss of microtubule stability as demonstrated by inconsecutive distribution of acetylated α-tubulin along the axons...
February 14, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28212979/degradation-of-optical-and-surface-properties-of-resin-based-composites-with-distinct-nanoparticle-sizes-but-equivalent-surface-area
#3
Vinícius Esteves Salgado, Larissa Maria Cavalcante, Rafael R Moraes, Harry B Davis, Jack L Ferracane, Luis Felipe Schneider
OBJECTIVE: To determine the optical and surface properties of model resin-based composites made with distinct nanoparticle sizes but equalized surface area, among them, before and after ageing. METHODS: Model resin-based composites based on BisGMA/TEGDMA (50:50mol%) were loaded with three different fumed silica filler content (7nm/examethyldisilazane, 12nm/octylsilane, and 16nm/dimethylchlorosilane), but with equivalent surface area (BET method). The optical and surface properties of the disk-shaped specimens were measured in 24h after photoactivation (baseline) and repeated after water storage (90days at 37°C), and after abrasion (20,000 cycles of brushing)...
February 14, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28211642/biomechanical-strain-exacerbates-inflammation-on-a-progeria-on-a-chip-model
#4
João Ribas, Yu Shrike Zhang, Patrícia R Pitrez, Jeroen Leijten, Mario Miscuglio, Jeroen Rouwkema, Mehmet Remzi Dokmeci, Xavier Nissan, Lino Ferreira, Ali Khademhosseini
Organ-on-a-chip platforms seek to recapitulate the complex microenvironment of human organs using miniaturized microfluidic devices. Besides modeling healthy organs, these devices have been used to model diseases, yielding new insights into pathophysiology. Hutchinson-Gilford progeria syndrome (HGPS) is a premature aging disease showing accelerated vascular aging, leading to the death of patients due to cardiovascular diseases. HGPS targets primarily vascular cells, which reside in mechanically active tissues...
February 17, 2017: Small
https://www.readbyqxmd.com/read/28211095/tooth-loss-among-the-elders-in-an-inner-city-area-of-ibadan-nigeria
#5
Olushola Ibiyemi, Ejiro Idiga
OBJECTIVE: To determine the prevalence and factors associated with tooth loss among elders in an inner city area of Ibadan, Nigeria. BACKGROUND: Tooth loss is an indication of the oral health of a population, and the possible effects of oral health on general health of the elders has been reported. MATERIAL AND METHODS: A cross-sectional study was undertaken among 392 consenting elders in Idikan, Ibadan, Nigeria. Information on socio-demographic characteristics, causes and effects of tooth loss was obtained using a pretested semistructured questionnaire...
February 16, 2017: Gerodontology
https://www.readbyqxmd.com/read/28210519/achondroplasia-in-the-premature-infant-an-elusive-diagnosis-in-the-neonatal-intensive-care-unit
#6
Kimberly E Fagen, Anna R Blask, Eva I Rubio, Dorothy I Bulas
Achondroplasia is a difficult prenatal diagnosis to make before the late second and third trimester. We describe two cases where an infant was born prematurely with no overt signs of achondroplasia. Despite multiple chest and abdominal radiographs during the neonatal course, the diagnosis was not made until term equivalent age was reached. We retrospectively reviewed these two cases to highlight the elusive findings of achondroplasia in the premature infant.
January 2017: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/28210479/pregnant-after-assisted-reproduction-a-risk-pregnancy-is-born-18-years-perinatal-outcome-results-from-a-population-based-registry-in-flanders-belgium
#7
W Ombelet, G Martens, L Bruckers
BACKGROUND: Although the increased risk for perinatal morbidity and mortality of babies born after ART is largely attributed to a higher rate of multiple gestations, a significantly worse perinatal outcome for singleton pregnancies following ART compared to pregnancies after natural conception has been reported as well. Most studies only include IVF/ICSI pregnancies; studies describing the perinatal outcome of pregnancies after non-IVF assisted reproduction are scarce. METHODS AND MATERIALS: Population-based cohort study with three exposure groups: a study group of pregnancies (1) after ovarian stimulation (OS), with or without artificial insemination (AI), (2) after IFV or ICSI and (3) a naturally conceived (NC) comparison group...
December 2016: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/28210452/ewing-sarcoma-of-the-oral-cavity-a-review
#8
REVIEW
Maria Margaix-Muñoz, José Bagán, Rafael Poveda-Roda
OBJECTIVES: A review is made of the clinical, diagnostic, therapeutic and survival characteristics of Ewing sarcoma (ES) of the oral cavity. MATERIAL AND METHODS: A systematic literature search was carried out, with restrictions referred to time (1960-2014), language (English and Spanish) and type of study (case reports, letters, datasets, reviews). The following MeSH terms and boolean operators were used: Ewing AND Sarcoma AND [tongue, jaw, maxilla, cheek, condyle OR temporomandibular, floor AND mouth, gum OR gingiva, palate OR palatal, lip, uvula, head AND neck]...
February 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28210010/evaluation-and-treatment-of-anemia-in-premature-infants
#9
Edo Hasanbegovic, Nermana Cengic, Snijezana Hasanbegovic, Jasmina Heljic, Ismail Lutolli, Edin Begic
INTRODUCTION: Anemia in preterm infants is the pathophysiological process with greater and more rapid decline in hemoglobin compared to the physiological anemia in infants. There is a need for transfusions and administration of human recombinant erythropoietin. AIM: To determine the frequency of anemia in premature infants at the Pediatric Clinic, University Clinical Center Sarajevo, as well as parameter values in the blood count of premature infants and to explore a relationship between blood transfusions with the advent of intraventricular hemorrhage (determine treatment outcome in preterm infants)...
December 2016: Medical Archives
https://www.readbyqxmd.com/read/28209927/improved-health-span-and-lifespan-in-mtdna-mutator-mice-treated-with-the-mitochondrially-targeted-antioxidant-skq1
#10
Irina G Shabalina, Mikhail Yu Vyssokikh, Natalia Gibanova, Robert I Csikasz, Daniel Edgar, Anne Hallden-Waldemarson, Zinaida Rozhdestvenskaya, Lora E Bakeeva, Valeria B Vays, Antonina V Pustovidko, Maxim V Skulachev, Barbara Cannon, Vladimir P Skulachev, Jan Nedergaard
MtDNA mutator mice exhibit marked features of premature aging. We find that these mice treated from age of ≈100 days with the mitochondria-targeted antioxidant SkQ1 showed a delayed appearance of traits of aging such as kyphosis, alopecia, lowering of body temperature, body weight loss, as well as ameliorated heart, kidney and liver pathologies. These effects of SkQ1 are suggested to be related to an alleviation of the effects of an enhanced reactive oxygen species (ROS) level in mtDNA mutator mice: the increased mitochondrial ROS released due to mitochondrial mutations probably interact with polyunsaturated fatty acids in cardiolipin, releasing malondialdehyde and 4-hydroxynonenal that form protein adducts and thus diminishes mitochondrial functions...
February 15, 2017: Aging
https://www.readbyqxmd.com/read/28209504/myopic-surface-ablation-in-asymmetrical-topographies-refractive-results-and-theoretical-corneal-elastic-response
#11
Luis F Brenner, Antonio Renna, Anna Pandolfi, Francisco C Martínez, Jorge L Alió
PURPOSE: To evaluate refractive results and the theoretical elastic response of photorefractive keratectomy in eyes with asymmetrical corneal surface and to compare such outcomes with a control-matched group of normal topographies. DESIGN: Retrospective interventional case series with matched comparison group. METHODS: 30 eyes with superior-inferior dioptric difference (SI index) > 1.40 D, were compared to 30 eyes with normal topographies...
February 13, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28208908/comparison-of-carotid-intima-media-thickness-in-children-of-patients-with-and-without-premature-coronary-artery-disease
#12
Alagesan Murali, Anith Kumar Mambatta, R R M Ranganathan, R Shanmugasundaram, K Deepalakshmi
INTRODUCTION: Increased Carotid Intima Medial Thickness (CIMT) is associated with cardiovascular risk factors and vascular events like Coronary Artery Disease (CAD) and stroke. AIM: This study was designed to identify whether CIMT is increased in the children of parents with premature coronary artery disease and compare it with age and sex matched controls who are children of normal individuals. We also tried to compare and correlate the changes in CIMT if any, among the study group with relation to family history of diabetes and hypertension...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28207960/improving-nutritional-practices-in-premature-infants-can-increase-their-growth-velocity-and-the-breastfeeding-rates
#13
Salvador Piris Borregas, María López Maestro, María José Torres Valdivieso, José Carlos Martínez Ávila, Gerardo Bustos Lozano, Carmen Rosa Pallás Alonso
AIM: This study analysed the changes in growth velocity (GV) of preterm infants weighing less than 1,500g based on different nutritional practices over a 24-year period. METHODS: A retrospective study with prospectively collected data was performed in a level three Spanish neonatal intensive care unit. Data on birth weight, gestational age (GA) and GV were collected from 1990 to 2013 and breastfeeding data was gathered from 2000. A generalised linear model corrected by GA and small for gestational age was applied...
February 16, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28207791/vitamin-d-and-mortality-individual-participant-data-meta-analysis-of-standardized-25-hydroxyvitamin-d-in-26916-individuals-from-a-european-consortium
#14
Martin Gaksch, Rolf Jorde, Guri Grimnes, Ragnar Joakimsen, Henrik Schirmer, Tom Wilsgaard, Ellisiv B Mathiesen, Inger Njølstad, Maja-Lisa Løchen, Winfried März, Marcus E Kleber, Andreas Tomaschitz, Martin Grübler, Gudny Eiriksdottir, Elias F Gudmundsson, Tamara B Harris, Mary F Cotch, Thor Aspelund, Vilmundur Gudnason, Femke Rutters, Joline W J Beulens, Esther van 't Riet, Giel Nijpels, Jacqueline M Dekker, Diana Grove-Laugesen, Lars Rejnmark, Markus A Busch, Gert B M Mensink, Christa Scheidt-Nave, Michael Thamm, Karin M A Swart, Ingeborg A Brouwer, Paul Lips, Natasja M van Schoor, Christopher T Sempos, Ramón A Durazo-Arvizu, Zuzana Škrabáková, Kirsten G Dowling, Kevin D Cashman, Mairead Kiely, Stefan Pilz
BACKGROUND: Vitamin D deficiency may be a risk factor for mortality but previous meta-analyses lacked standardization of laboratory methods for 25-hydroxyvitamin D (25[OH]D) concentrations and used aggregate data instead of individual participant data (IPD). We therefore performed an IPD meta-analysis on the association between standardized serum 25(OH)D and mortality. METHODS: In a European consortium of eight prospective studies, including seven general population cohorts, we used the Vitamin D Standardization Program (VDSP) protocols to standardize 25(OH)D data...
2017: PloS One
https://www.readbyqxmd.com/read/28206997/pulmonary-hypertension-in-preterm-infants-results-of-a-prospective-screening-program
#15
C G Weismann, J D Asnes, A Bazzy-Asaad, C Tolomeo, R A Ehrenkranz, M J Bizzarro
OBJECTIVE: Determine prevalence and associations with pulmonary hypertension (PH) in preterm infants. STUDY DESIGN: Prospective institutional echocardiographic PH screening at 36 to 38 weeks' corrected gestational age (GA) for infants born <32 weeks' GA who had bronchopulmonary dysplasia (BPD; group BPD), and infants without BPD who had a birth weight (BW) <750 g, or clinical suspicion for PH (group NoBPD). RESULTS: Two hundred and four infants were screened (GA 25...
February 16, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28206993/hemodynamic-effects-of-sodium-bicarbonate-administration
#16
A C Katheria, M K Brown, K Hassan, D M Poeltler, D A Patel, V K Brown, J B Sauberan
OBJECTIVE: To describe the hemodynamic changes that occur with sodium bicarbonate (NaHCO3) administration in premature neonates. STUDY DESIGN: This retrospective study included premature neonates 23 to 31+6 weeks of gestational age who underwent continuous cardiac and cerebral monitoring as participants in prospective trials at our institution, and who received NaHCO3 infused over 30 min in the first 24 h of life. Blood pressure (BP), heart rate, cardiac output (CO), SpO2 and cerebral oximetry (StO2) were captured every 2 s...
February 16, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28205331/new-insights-to-the-mechanisms-underlying-atherosclerosis-in-rheumatoid-arthritis
#17
REVIEW
Mahdi Mahmoudi, Saeed Aslani, Reza Fadaei, Ahmad Reza Jamshidi
Rheumatoid arthritis (RA) is an inflammatory circumstance, which has been associated with increased risk of cardiovascular disease (CVD). Although RA management has been promoted, mortality rate due to CVD remains remarkable. Approximately, 50% of premature death cases in RA are attributable to CVD. RA patients develop atherosclerosis in a greater amount than the general population. Moreover, atherosclerotic lesions develop rapidly in RA patients and might be more susceptible to rupture. The inflammatory condition of RA, such as cytokines, abnormally activated immune cells, play a role in the initiation, perpetuation and exacerbation of atherosclerosis...
February 16, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28205208/skin-to-skin-care-for-procedural-pain-in-neonates
#18
REVIEW
Celeste Johnston, Marsha Campbell-Yeo, Timothy Disher, Britney Benoit, Ananda Fernandes, David Streiner, Darlene Inglis, Rebekah Zee
BACKGROUND: Skin-to-skin care (SSC), often referred to as 'kangaroo care' (KC) due to its similarity with marsupial behaviour of ventral maternal-infant contact, is one non-pharmacological intervention for pain control in infants. OBJECTIVES: The primary objectives were to determine the effect of SSC alone on pain from medical or nursing procedures in neonates compared to no intervention, sucrose or other analgesics, or additions to simple SSC such as rocking; and to determine the effects of the amount of SSC (duration in minutes), method of administration (e...
February 16, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28205118/association-of-serum-gamma-glutamyltransferase-and-premature-coronary-artery-disease
#19
M Sheikh, M Tajdini, A Shafiee, M Sotoudeh Anvari, A Jalali, H Poorhosseini, A Amirzadegan
BACKGROUND: Serum gamma-glutamyltransferase (GGT) has been introduced as a predictive factor for cardiovascular disease. In this study, we investigated the association of serum GGT and premature coronary artery disease (CAD) in candidates for coronary angiography. METHODS: In this cross-sectional study, we enrolled male subjects aged ≤45 years and female subjects ≤55 years who were candidates for elective coronary angiography due to typical chest pain or a positive non-invasive test...
February 15, 2017: Netherlands Heart Journal
https://www.readbyqxmd.com/read/28204988/outcome-of-solid-state-532%C3%A2-nm-green-laser-in-high-risk-retinopathy-of-prematurity-at-a-tertiary-care-centre-in-india
#20
Kanika Chhabra, Prempal Kaur, Karamjit Singh, Anand Aggarwal, Dharamvir Chalia
PURPOSE: The purpose of this study was to analyse the outcome of solid-state green laser in high-risk retinopathy of prematurity (ROP) at a tertiary centre in India. METHODS: Fifty-nine eyes of 30 infants with high-risk ROP were recruited in this prospective, interventional study. High-risk ROP included prethreshold type 1 ROP and APROP. Laser photocoagulation was performed with 532 nm solid-state green laser (Novus Spectra, Lumenis, GmbH, Germany). RESULTS: Of the 30 infants, 18 were males (60%) and 12 were females (40%)...
February 15, 2017: International Ophthalmology
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