keyword
https://read.qxmd.com/read/34368630/fifteen-years-of-the-australian-imaging-biomarkers-and-lifestyle-aibl-study-progress-and-observations-from-2-359-older-adults-spanning-the-spectrum-from-cognitive-normality-to-alzheimer-s-disease
#21
JOURNAL ARTICLE
Christopher Fowler, Stephanie R Rainey-Smith, Sabine Bird, Julia Bomke, Pierrick Bourgeat, Belinda M Brown, Samantha C Burnham, Ashley I Bush, Carolyn Chadunow, Steven Collins, James Doecke, Vincent Doré, Kathryn A Ellis, Lis Evered, Amir Fazlollahi, Jurgen Fripp, Samantha L Gardener, Simon Gibson, Robert Grenfell, Elise Harrison, Richard Head, Liang Jin, Adrian Kamer, Fiona Lamb, Nicola T Lautenschlager, Simon M Laws, Qiao-Xin Li, Lucy Lim, Yen Ying Lim, Andrea Louey, S Lance Macaulay, Lucy Mackintosh, Ralph N Martins, Paul Maruff, Colin L Masters, Simon McBride, Lidija Milicic, Madeline Peretti, Kelly Pertile, Tenielle Porter, Morgan Radler, Alan Rembach, Joanne Robertson, Mark Rodrigues, Christopher C Rowe, Rebecca Rumble, Olivier Salvado, Greg Savage, Brendan Silbert, Magdalene Soh, Hamid R Sohrabi, Kevin Taddei, Tania Taddei, Christine Thai, Brett Trounson, Regan Tyrrell, Michael Vacher, Shiji Varghese, Victor L Villemagne, Michael Weinborn, Michael Woodward, Ying Xia, David Ames
BACKGROUND: The Australian Imaging, Biomarkers and Lifestyle (AIBL) Study commenced in 2006 as a prospective study of 1,112 individuals (768 cognitively normal (CN), 133 with mild cognitive impairment (MCI), and 211 with Alzheimer's disease dementia (AD)) as an 'Inception cohort' who underwent detailed ssessments every 18 months. Over the past decade, an additional 1247 subjects have been added as an 'Enrichment cohort' (as of 10 April 2019). OBJECTIVE: Here we provide an overview of these Inception and Enrichment cohorts of more than 8,500 person-years of investigation...
2021: JAD Reports
https://read.qxmd.com/read/33981947/bringing-policymakers-to-science-through-communication-a-perspective-from-latin-america
#22
JOURNAL ARTICLE
Marta Pulido-Salgado, Fátima Antonethe Castaneda Mena
Scientific knowledge should be shared beyond academic circles in order to promote science in policymaking. Science communication increases the understanding of how the natural world works and the capacity to make informed decisions. However, not every researcher has the ability to master the art of communicating, and even less in a clear, concise, and easy to understand language that society representatives appreciate. Within the huge and extraordinarily diverse Latin American region, science communication has been going on for at least 200 years, when the first science stories appeared in the newspapers, as well as the first science museums and botanical gardens were founded...
2021: Frontiers in Research Metrics and Analytics
https://read.qxmd.com/read/33935071/longitudinal-trajectories-in-cortical-thickness-and-volume-atrophy-superior-cognitive-performance-does-not-protect-against-brain-atrophy-in-older-adults
#23
JOURNAL ARTICLE
Samantha L Gardener, Michael Weinborn, Hamid R Sohrabi, James D Doecke, Pierrick Bourgeat, Stephanie R Rainey-Smith, Kai-Kai Shen, Jurgen Fripp, Kevin Taddei, Paul Maruff, Olivier Salvado, Greg Savage, David Ames, Colin L Masters, Christopher C Rowe, Ralph N Martins
BACKGROUND: Previous research has identified a small subgroup of older adults that maintain a high level of cognitive functioning well into advanced age. Investigation of those with superior cognitive performance (SCP) for their age is important, as age-related decline has previously been thought to be inevitable. OBJECTIVE: Preservation of cortical thickness and volume was evaluated in 76 older adults with SCP and 100 typical older adults (TOAs) assessed up to five times over six years...
April 27, 2021: Journal of Alzheimer's Disease: JAD
https://read.qxmd.com/read/33805778/plasma-amyloid-beta-levels-in-a-pre-symptomatic-dutch-type-hereditary-cerebral-amyloid-angiopathy-pedigree-a-cross-sectional-and-longitudinal-investigation
#24
JOURNAL ARTICLE
Pratishtha Chatterjee, Michelle Tegg, Steve Pedrini, Anne M Fagan, Chengjie Xiong, Abhay K Singh, Kevin Taddei, Samantha Gardener, Colin L Masters, Peter R Schofield, Gerhard Multhaup, Tammie L S Benzinger, John C Morris, Randall J Bateman, Steven M Greenberg, Mark A van Buchem, Erik Stoops, Hugo Vanderstichele, Charlotte E Teunissen, Graeme J Hankey, Marieke J H Wermer, Hamid R Sohrabi, Ralph N Martins, The Dominantly Inherited Alzheimer Network
Plasma amyloid-beta (Aβ) has long been investigated as a blood biomarker candidate for Cerebral Amyloid Angiopathy (CAA), however previous findings have been inconsistent which could be attributed to the use of less sensitive assays. This study investigates plasma Aβ alterations between pre-symptomatic Dutch-type hereditary CAA (D-CAA) mutation-carriers (MC) and non-carriers (NC) using two Aβ measurement platforms. Seventeen pre-symptomatic members of a D-CAA pedigree were assembled and followed up 3-4 years later (NC = 8; MC = 9)...
March 13, 2021: International Journal of Molecular Sciences
https://read.qxmd.com/read/33659763/southwest-harvest-for-health-adapting-a-mentored-vegetable-gardening-intervention-for-cancer-survivors-in-the-southwest
#25
JOURNAL ARTICLE
Cindy K Blair, Elizabeth M Harding, Prajakta Adsul, Sara Moran, Dolores Guest, Kathy Clough, Andrew L Sussman, Dorothy Duff, Linda S Cook, Joseph Rodman, Zoneddy Dayao, Ursa Brown-Glaberman, Towela V King, V Shane Pankratz, Eduardo Servin, Sally Davis, Wendy Demark-Wahnefried
Few diet and physical activity evidence-based interventions have been routinely used in community settings to achieve population health outcomes. Adapting interventions to fit the implementation context is important to achieve the desired results. Harvest for Health is a home-based vegetable gardening intervention that pairs cancer survivors with certified Master Gardeners from the Cooperative Extension Service with the ultimate goal of increasing vegetable consumption and physical activity, and improving physical functioning and health-related quality-of-life...
March 2021: Contemporary Clinical Trials Communications
https://read.qxmd.com/read/33491880/molecular-evaluation-of-toxocara-species-in-stray-cats-using-loop-mediated-isothermal-amplification-lamp-technique-as-a-rapid-sensitive-and-simple-screening-assay
#26
JOURNAL ARTICLE
Hamid Azimian, Hamidreza Shokrani, Shirzad Fallahi
Toxocara species are parasitic nematodes of dogs and cats with a worldwide distribution. The adult worm lives in the intestine, and horizontal transmission of the infection occurs through eating paratenic host or embryonated eggs. This study aimed to estimate the molecular prevalence of Toxocara species in stray cats using the loop-mediated isothermal amplification (LAMP) technique. A total of 95 stool samples were randomly collected from stray cats in Khorramabad city in western Iran. Microscopic examination was performed after the separation and extraction of supernatants...
January 25, 2021: Veterinary Medicine and Science
https://read.qxmd.com/read/33361604/presymptomatic-dutch-type-hereditary-cerebral-amyloid-angiopathy-related-blood-metabolite-alterations
#27
JOURNAL ARTICLE
Pratishtha Chatterjee, Anne M Fagan, Chengjie Xiong, Matthew McKay, Atul Bhatnagar, Yunqi Wu, Abhay K Singh, Kevin Taddei, Ian Martins, Samantha L Gardener, Mark P Molloy, Gerhard Multhaup, Colin L Masters, Peter R Schofield, Tammie L S Benzinger, John C Morris, Randall J Bateman, Steven M Greenberg, Marieke J H Wermer, Mark A van Buchem, Hamid R Sohrabi, Ralph N Martins
BACKGROUND: Cerebral amyloid angiopathy (CAA) is one of the major causes of intracerebral hemorrhage and vascular dementia in older adults. Early diagnosis will provide clinicians with an opportunity to intervene early with suitable strategies, highlighting the importance of pre-symptomatic CAA biomarkers. OBJECTIVE: Investigation of pre-symptomatic CAA related blood metabolite alterations in Dutch-type hereditary CAA mutation carriers (D-CAA MCs). METHODS: Plasma metabolites were measured using mass-spectrometry (AbsoluteIDQ® p400 HR kit) and were compared between pre-symptomatic D-CAA MCs (n = 9) and non-carriers (D-CAA NCs, n = 8) from the same pedigree...
December 24, 2020: Journal of Alzheimer's Disease: JAD
https://read.qxmd.com/read/32659016/leela-mulherkar-and-the-teaching-of-developmental-biology
#28
JOURNAL ARTICLE
Surendra Ghaskadbi
The formal teaching of developmental biology in India began in the late nineteen-fifties at the Department of Zoology of the University of Poona. This was due to the efforts of Leela Mulherkar, who on her return from C.H. Waddington's laboratory in Edinburgh, took up the teaching of embryology at the Master's level. Mulherkar began using locally available material to teach how animals develop. They included the embryos of chicken, frog, garden lizard and molluscs, as well as organisms such as hydra and sponges...
2020: International Journal of Developmental Biology
https://read.qxmd.com/read/32548998/history-of-islamic-medical-schools-in-turkey-s-territory
#29
JOURNAL ARTICLE
Selman Çıkmaz, Recep Mesut
In today's political borders of the Republic of Turkey there exists very old institutions that train physicians according to Islamic medical science. In this study, 19 health institutions, whose locations have been determined and documents have been finalized, are approached in chronological order and classified according to historical periods: XIIth-XIIIth centuries (Seljukian period) - 10; XIVth century (Ilkhanate dominion) - 1; XVth-XVIIth centuries (Ottoman period) - 8 institutions. Some of them have a history of 900 years (Konya Maristan-ı Atik, 1113; Mardin Eminüddin Bimaristanı, 1122)...
June 17, 2020: Balkan Medical Journal
https://read.qxmd.com/read/31891111/the-living-green-infrastructure-lab-advancing-interdisciplinary-teaching-and-experiential-learning-in-landscape-architecture-pedagogy
#30
JOURNAL ARTICLE
Zhihan Tao, Galen Newman, Michael Arnold, Ming-Han Li, Jun-Hyun Kim
Demonstrating and experimenting interdisciplinary teaching and experiential learning, faculty and students across three colleges (Agriculture and Life Sciences, Architecture and Engineering), and 4 departments (Landscape Architecture and Urban Planning, Horticultural Sciences, and Civil, Biological and Agricultural Engineering) designed, implemented, and are monitoring effects of a rain garden. This collaboration presents a model for multi-scalar, interdisciplinary studio instruction involving a project conducted by over 200 undergraduate and graduate students across allied fields...
March 2019: Landscape research record
https://read.qxmd.com/read/31743586/labels-of-insecticides-that-could-be-exposed-to-oregon-honey-bee-apis-mellifera-l-hives-do-not-align-with-federal-recommendations-in-their-communication-of-acute-and-residual-toxicity-to-honey-bees
#31
JOURNAL ARTICLE
Matthew T Bucy, Andony Melathopoulos
BACKGROUND: Teaching pesticide applicators how to determine a product's toxicity to honey bees (Apis mellifera L.) by understanding the label is a way to reduce honey bee exposure to pesticides. Applicators are currently taught how to interpret labels that follow the United States Environmental Protection Agency's (USEPA's) recommendations for how this toxicity should be communicated. To effectively educate applicators, it must be determined if labels follow USEPA recommendations in how they communicate toxicity to honey bees, and if they do not, what patterns exist in these deviations from the recommendations (hereafter, deviations)...
November 19, 2019: Pest Management Science
https://read.qxmd.com/read/31580754/opportunities-for-growth-evaluating-the-feasibility-of-a-community-gardening-intervention-pairing-adolescent-and-young-adult-cancer-survivors-with-experienced-gardeners
#32
JOURNAL ARTICLE
Renate M Winkels, Rick Artrip, Maegan Tupinio, Susan Veldheer, Smita C Dandekar, Daniel R George
We evaluated the feasibility of a mentored gardening intervention for adolescent and young adult (AYA) cancer survivors in a hospital-based community garden as a way to improve diet and physical activity, using qualitative data to assess the challenges, facilitators, and areas for future programmatic improvement and replication. Over the course of growing season 2018, AYA cancer survivors tended a garden plot in a community garden under the mentorship of an experienced (master) gardener. AYA cancer survivors were successful in planting and harvesting vegetables from the garden in partnership with their mentors...
October 3, 2019: Journal of Adolescent and Young Adult Oncology
https://read.qxmd.com/read/31106175/shaping-plastic-surgery-in-british-columbia-the-courtemanche-legacy
#33
JOURNAL ARTICLE
Yaeesh Sardiwalla, Steven F Morris
Dr Albert Douglas Courtemanche was born in Gravenhurst, Ontario on November 16, 1929. In 1949, he was accepted to the University of Toronto Medical School, graduating in 1955. After completing his internship at the Toronto General Hospital and at the Hospital for Sick Children, he completed his surgical training in Vancouver and in the United Kingdom. When Dr Courtemanche returned from his training in 1962, he joined Dr Cowan on the surgical staff at the Vancouver General Hospital. He was responsible for establishing a new plastic surgery ward, a dedicated operating room (OR), an integrated burn unit and also starting the UBC plastic surgery training program...
May 2019: Plastic Surgery
https://read.qxmd.com/read/30375373/mediterranean-diet-adherence-and-rate-of-cerebral-a%C3%AE-amyloid-accumulation-data-from-the-australian-imaging-biomarkers-and-lifestyle-study-of-ageing
#34
JOURNAL ARTICLE
Stephanie R Rainey-Smith, Yian Gu, Samantha L Gardener, James D Doecke, Victor L Villemagne, Belinda M Brown, Kevin Taddei, Simon M Laws, Hamid R Sohrabi, Michael Weinborn, David Ames, Christopher Fowler, S Lance Macaulay, Paul Maruff, Colin L Masters, Olivier Salvado, Christopher C Rowe, Nikolaos Scarmeas, Ralph N Martins
Accumulating research has linked Mediterranean diet (MeDi) adherence with slower cognitive decline and reduced Alzheimer's disease (AD) risk. However, no study to-date has examined the relationship between MeDi adherence and accumulation of cerebral Aβ-amyloid (Aβ; a pathological hallmark of AD) in older adults. Cognitively normal healthy control participants of the Australian Imaging, Biomarkers and Lifestyle (AIBL) Study of Ageing completed the Cancer Council of Victoria Food Frequency Questionnaire at baseline, which was used to construct a MeDi score for each participant (score range 0-9; higher score indicating higher adherence)...
October 30, 2018: Translational Psychiatry
https://read.qxmd.com/read/30281801/functional-trait-divergence-and-trait-plasticity-confer-polyploid-advantage-in-heterogeneous-environments
#35
JOURNAL ARTICLE
Na Wei, Richard Cronn, Aaron Liston, Tia-Lynn Ashman
Polyploidy, or whole-genome duplication often with hybridization, is common in eukaryotes and is thought to drive ecological and evolutionary success, especially in plants. The mechanisms of polyploid success in ecologically relevant contexts, however, remain largely unknown. We conducted an extensive test of functional trait divergence and plasticity in conferring polyploid fitness advantage in heterogeneous environments, by growing clonal replicates of a worldwide genotype collection of six allopolyploid and five diploid wild strawberry (Fragaria) taxa in three climatically different common gardens...
October 3, 2018: New Phytologist
https://read.qxmd.com/read/29970838/development-of-igrow-a-curriculum-for-youth-adult-dyads-to-increase-gardening-skills-culinary-competence-and-family-meal-time-for-youths-and-their-adult-caregivers
#36
JOURNAL ARTICLE
Jade A White, Rebecca L Hagedorn, Nicole L Waterland, Makenzie L Barr, Oluremi A Famodu, Amy E Root, Adrienne A White, Sarah E Colby, Lisa Franzen-Castle, Kendra K Kattelmann, Melissa D Olfert
This manuscript describes the development of a “learn by actively participating” curriculum for youth and their adult caregivers (dyad pair) to increase gardening skills, culinary competence, and family meal time. The curriculum was developed by integrating “iCook 4-H” and Junior Masters Gardener “Health and Nutrition from the Garden”, and “Essential Elements of 4-H Youth Development” curriculums with additional resources for gardening activities from the USDA’s My Plate and garden-based recipes...
July 3, 2018: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/29932460/a-home-based-mentored-vegetable-gardening-intervention-demonstrates-feasibility-and-improvements-in-physical-activity-and-performance-among-breast-cancer-survivors
#37
JOURNAL ARTICLE
Jennifer R Bail, Andrew D Frugé, Mallory G Cases, Jennifer F De Los Santos, Julie L Locher, Kerry P Smith, Alan B Cantor, Harvey J Cohen, Wendy Demark-Wahnefried
BACKGROUND: The current study assessed the feasibility of a mentored home-based vegetable gardening intervention and examined changes in health-related outcomes among breast cancer survivors (BCS). METHODS: BCS were randomized to either a year-long vegetable gardening intervention to begin immediately or a wait-list control. Master Gardeners mentored participants in planning, planting, and maintaining 3 seasonal gardens over the course of 1 year. Participant accrual, retention, and satisfaction rates of ≥80% served as feasibility (primary outcome) benchmarks...
August 2018: Cancer
https://read.qxmd.com/read/29904038/-that-guy-is-he-really-sick-at-all-an-analysis-of-how-veterans-with-ptsd-experience-nature-based-therapy
#38
JOURNAL ARTICLE
Dorthe Varning Poulsen, Ulrika K Stigsdotter, Annette Sofie Davidsen
Serving in the military leads to mental diseases, such as post-traumatic stress disorder (PTSD), for a percentage of soldiers globally. The number of veterans with PTSD is increasing and, although medication and psychological treatments are offered, treatment results could be improved. Historically, different forms of nature-based therapy have been used for this target group. However, in spite of anecdotally good results, studies measuring the effect of this form of therapy are still lacking. The aim of this study is to explore how veterans with PTSD manage their everyday lives during and after a ten-week nature-based intervention in a therapy garden...
June 14, 2018: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/29781669/trajectories-of-irregular-word-reading-ability-as-a-proxy-for-premorbid-intelligence-in-alzheimer-s-disease-mild-cognitive-impairment-and-healthy-aging-a-longitudinal-study
#39
JOURNAL ARTICLE
Michael Weinborn, Romola S Bucks, Hamid R Sohrabi, Stephanie R Rainey-Smith, Belinda M Brown, Samantha L Gardener, Aleksandra Gozt, Daniel Christensen, Greg Savage, Simon M Laws, Kevin Taddei, Paul Maruff, Joanne S Robertson, Kathryn A Ellis, David Ames, Colin L Masters, Christopher C Rowe, Ralph N Martins
The ability to read irregularly spelled words is commonly used to estimate premorbid intelligence, as this ability has been thought to be resistant to early effects of neurodegenerative disorders. However, studies evaluating decline of this skill in Alzheimer's disease (AD) have produced conflicting results. Irregular word reading was assessed three times over 36 months in a large (N = 995) sample, including healthy control, AD, and Mild Cognitive Impairment (MCI) groups. At baseline, MCI and AD groups read correctly an average of 3...
October 2018: Psychological Assessment
https://read.qxmd.com/read/29576999/the-effect-of-chitosan-pmaa-npk-nanofertilizer-on-pisum-sativum-plants
#40
JOURNAL ARTICLE
Noha S Khalifa, Mohammed N Hasaneen
The use of chitosan (CS) as a carrier for slow fertilizer release is a novel trend. The potential effect of this system in agriculture is still debatable. Here, chitosan (CS) nanoparticles were obtained by polymerizing methacrylic acid (PMAA) for the entrapment of nitrogen, phosphorous and potassium (NPK) nanoparticles (NP), each at a time to form CS-PMAA-NPK NPs complex. The impact of this complex was evaluated using garden pea ( Pisum sativum var. Master B) plants. Five-day-old pea seedlings were treated through their root system with CS-PMAA-NPK NPs at concentrations of 1, 0...
April 2018: 3 Biotech
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