keyword
https://read.qxmd.com/read/38530302/octa-signal-quality-augmentation-using-the-isometric-handgrip-test-to-maximize-vascular-flow%C3%A2-squeeze-a%C3%A2-randomized-crossover-trial
#21
RANDOMIZED CONTROLLED TRIAL
Matt Trinh, Judy Nam, Meenakshi Kumar, Lisa Nivison-Smith
PURPOSE: To determine if performing the isometric handgrip test (IHGT) can augment optical coherence tomography angiography (OCTA) vascular signal quality in eyes with macular abnormalities. METHODS: A randomized, single-blinded crossover trial was conducted including 36 participants with macular abnormalities, randomized to undergo OCTA with or without the IHGT, then crossed over to the alternate "intervention" after 1 minute. The primary outcome was OCTA signal quality after 1 minute of squeezing at 50% maximum grip strength...
March 1, 2024: Translational Vision Science & Technology
https://read.qxmd.com/read/38530020/intra-operative-duplex-ultrasound-scanning-in-renal-transplantation-protocol-and-service-requirements
#22
Linda Thebridge, Charles Fisher, Vikram Puttaswamy, Carol Pollock, Jillian Clarke
Intra-operative duplex ultrasound in renal transplantation was first described in 1998 and whilst reported in problematic cases, there are few reports of its routine use and no current published protocols. Since 2013, we have used intra-operative ultrasound in all renal transplants. The formal protocol used since August 2020 is presented as a reference document for other transplant centres. A Canon Aplio 800 ultrasound system with an i22LH8 hockey-stick transducer is used to image the renal cortex and major vessels, and an i8CX1 matrix transducer to image the graft during and after fascial closure...
March 26, 2024: Journal of Medical Radiation Sciences
https://read.qxmd.com/read/38529996/rapid-intervention-team-strategy-improves-intervention-quality-for-patients-undergoing-hemodialysis-with-arteriovenous-shunt-dysfunction-or-failure
#23
JOURNAL ARTICLE
Szu-Han Wang, Chih-Chang Ko, Yi-Ling Kuo, Yu-Wen Chiu, Jih-Sheng Wen, Ming-Cheng Wang, Ting-Hsing Chao, Hsien-Yuan Chang
BACKGROUND: Vascular access dysfunction is a great burden for hemodialysis patients. Early intervention of a dysfunctional arteriovenous shunt is associated with higher technical success and may improve midterm patency. This trial aimed to estimate the feasibility of a new system, the "rapid intervention team" (RIT) strategy. METHODS: We recruited hemodialysis patients who visited our hospital because of arteriovenous shunt dysfunction or failure to undergo an RIT strategy from September 1, 2019, to December 31, 2022...
March 26, 2024: Journal of the Chinese Medical Association: JCMA
https://read.qxmd.com/read/38529458/improving-the-quality-of-operative-notes-in-vascular-surgery-a-retrospective-analysis
#24
JOURNAL ARTICLE
Munzir Akasha, Ahmmad Alfatih, Mohamedali Mohamed, Yogesh Acharya, Mahmoud Alawy
Background and objective Missing information or mistakes in patients' medical records, including those related to intraoperative and postoperative information, in an operative note can have profound clinical, ethical, and medicolegal implications. Operative notes should be informative, clear, and inclusive of the necessary data and should be collated immediately following surgery. In this study, we aimed to determine the ways to improve the quality of operative notes in the field of vascular surgery. Methods In this retrospective analysis, we compared the operative notes of 32 patients in the Department of Vascular and Endovascular Surgery, University Hospital Galway, against the standard set by the Royal College of Surgeons in Ireland (RCSI) (Code of Practice for Surgeons RCSI, 2018) and presented the results to our departmental staff...
February 2024: Curēus
https://read.qxmd.com/read/38529446/topical-dorzolamide-as-adjunctive-treatment-with-intravitreal-bevacizumab-in-bilateral-diabetic-macular-edema
#25
JOURNAL ARTICLE
Ata Sadr, Meisam Sargazi, Shahram Banaie, Mahdi Asani, Hassan Mehrad Majd, Seyed Omid Mohammadi, Alireza Maleki
BACKGROUND:  Intravitreal injection of anti-vascular endothelial growth factor (VEGF) agents is accepted as the gold standard treatment for center-involving diabetic macular edema (CI-DME). Adjunctive administration of topical dorzolamide may enhance the therapeutic effects of anti-VEGF agents. In this study, we compared the efficacy of topical dorzolamide plus intravitreal injection of bevacizumab (IVB) versus IVB alone in patients with bilateral DME. METHODS: This prospective, randomized contralateral eye study was carried out in a tertiary referral ophthalmology center, Al-Zahra Eye Hospital, Zahedan, Iran, between April 2021 and April 2022...
February 2024: Curēus
https://read.qxmd.com/read/38528599/local-alternating-heat-and-cold-stimulation-affects-hemodynamics-and-oxygenation-in-fatigued-muscle-tissue-and-autonomic-nervous-activity-a-single-arm-interventional-study
#26
JOURNAL ARTICLE
Tomonori Sawada, Hiroki Okawara, Daisuke Nakashima, Kentaro Aoki, Mira Namba, Shuhei Iwabuchi, Yoshinori Katsumata, Masaya Nakamura, Takeo Nagura
BACKGROUND: Local alternating heat and cold stimulation as an alternative to contrast bath may cause intermittent vasoconstriction and vasodilation, inducing a vascular pumping effect and consequently promoting increased tissue blood flow and oxygenation. This study aimed to examine the effects of local alternating heat and cold stimulation, using a wearable thermal device, on the hemodynamics of fatigued muscle tissue and autonomic nervous activity. METHODS: Twenty healthy individuals experienced fatigue in the periarticular muscles of the shoulder joint due to a typing task...
March 25, 2024: Journal of Physiological Anthropology
https://read.qxmd.com/read/38528277/pre-hospital-emergency-medicine-a-spectrum-of-imaging-findings
#27
REVIEW
Ryan T Whitesell, Aaron M Burnett, Sean K Johnston, Douglas H Sheafor
The goal of emergency medical services (EMS) is to provide urgent medical care and stabilization prior to patient transport to a healthcare facility for definitive treatment. The number and variety of interventions performed in the field by EMS providers continues to grow as early management of severe injuries and critical illness in the pre-hospital setting has been shown to improve patient outcomes. The sequela of many field interventions, including those associated with airway management, emergent vascular access, cardiopulmonary resuscitation (CPR), patient immobilization, and hemorrhage control may be appreciated on emergency department admission imaging...
March 26, 2024: Emergency Radiology
https://read.qxmd.com/read/38527946/endotension-following-endovascular-aneurysm-repair-retrospective-review-of-treatment-and-clinical-outcome
#28
JOURNAL ARTICLE
Joon-Young Kim, Sang Ah Lee, Jun Gyo Gwon, Youngjin Han, Yong-Pil Cho, Tae-Won Kwon
PURPOSE: : Endotension is a rare late complication characterized by an increase in sac size without any type of endoleak following endovascular aortic aneurysm repair (EVAR). Due to its rarity, few studies have demonstrated the mechanism behind and the management of endotension. In this study, we aimed to better understand the treatment and the long-term outcome of endotension in a single-center cohort. MATERIALS AND METHODS: : This study was designed for a retrospective review of the patients diagnosed with endotension between January 2006 and December 2017...
March 26, 2024: Vascular Specialist International
https://read.qxmd.com/read/38527712/exploring-the-neuroprotective-role-of-physical-activity-in-cerebral-small-vessel-disease
#29
REVIEW
Maria E Anderson, Eleanor J Wind, Lisa S Robison
Cerebral Small Vessel Disease (cSVD) is a common neurological finding characterized by abnormalities of the small blood vessels in the brain. Previous research has established a strong connection between cSVD and stroke, as well as neurodegenerative disorders, notably Alzheimer's disease (AD) and other dementias. As the search for effective interventions continues, physical activity (PA) has emerged as a potential preventative and therapeutic avenue. This review synthesizes the human and animal literature on the influence of PA on cSVD, highlighting the importance of determining optimal exercise protocols, considering aspects such as intensity, duration, timing, and exercise type...
March 23, 2024: Brain Research
https://read.qxmd.com/read/38527519/long-term-outcomes-of-the-gore-excluder-low-permeability-endoprosthesis-for-the-treatment-of-infrarenal-aortic-aneurysms
#30
JOURNAL ARTICLE
Stefan P M Smorenburg, Jorg L de Bruin, Clark J Zeebregts, Michel M P J Reijnen, Hence J M Verhagen, Jan M M Heyligers
OBJECTIVE: This study evaluated the long term outcomes of endovascular aneurysm repair using the Gore Excluder Low Permeability (LP) endoprosthesis across high volume Dutch hospitals. METHODS: A retrospective analysis was conducted of patients treated with the Excluder LP for infrarenal abdominal aortic aneurysm (AAA) in four hospitals between 2004 - 2017. Primary outcomes were overall survival, freedom from re-interventions (overall, inside/outside instructions for use, IFU), and AAA sac dynamics: growth (> 5 mm), stabilisation, and regression (< 5 mm)...
March 23, 2024: European Journal of Vascular and Endovascular Surgery
https://read.qxmd.com/read/38526708/role-of-c-ebp-homologous-protein-in-vascular-stenosis-after-carotid-artery-injury
#31
JOURNAL ARTICLE
Lin Teng, Qin Qin, Zi-Yi Zhou, Fei Zhou, Cun-Yu Cao, Chao He, Jia-Wang Ding, Jian Yang
The study aims to explore the fluctuating expression of C/EBP Homologous Protein (CHOP) following rat carotid artery injury and its central role in vascular stenosis. Using in vivo rat carotid artery injury models and in vitro ischemia and hypoxia cell models employing human aortic endothelial cells (HAECs) and vascular smooth muscle cells (T/G HA-VSMCs), a comprehensive investigative framework was established. Histological analysis confirmed intimal hyperplasia in rat models. CHOP expression in vascular tissues was assessed using Western blot and immunohistochemical staining, and its presence in HAECs and T/G HA-VSMCs was determined through RT-PCR and Western blot...
March 25, 2024: Biochemical Genetics
https://read.qxmd.com/read/38526009/enhancing-root-coverage-and-esthetic-outcomes-in-isolated-gingival-recession-using-orthodontic-intervention-and-lateral-closed-tunnel-technique-an-interdisciplinary-prospective-case-series
#32
Neelima Katti, Rimsha Kp, Ashish Kumar Barik, Surya Kanta Das, Srivani Peri, Devapratim Mohanty
BACKGROUND: Gingival recession (GR) in malposed tooth in association with bone dehiscence and/or fenestration poses a challenge for successful root coverage treatment. Lateral closed tunnel (LCT) technique is particularly useful in isolated GR in mandibular anterior region, where the shallow vestibular depth prevents tension-free coronal mobilization of tissues. METHODS: Twenty patients with GR associated with tooth malposition were treated using a combined orthodontic-periodontic approach with a torquing auxiliary spring followed by LCT technique...
March 25, 2024: Clinical Advances in Periodontics
https://read.qxmd.com/read/38525944/advanced-glycation-endproducts-a-marker-of-long-term-exposure-to-glycemia
#33
JOURNAL ARTICLE
David C Klonoff, Rachel E Aaron, Tiffany Tian, Ashley Y DuNova, Ambarish Pandey, Connie Rhee, G Alexander Fleming, David B Sacks, Rodica Pop-Busui, David Kerr
This article examines the importance of advanced glycation endproducts (AGEs) and summarizes the structure of AGEs, pathological changes associated with AGEs, the contribution of AGEs to metabolic memory, and the value of AGEs as a predictor of diabetic complications and cardiovascular disease in people with and without diabetes. As a practical focus, skin autofluorescence (SAF) is examined as an attractive approach for estimating AGE burden. The measurement of AGEs may be of significant value to specific individuals and groups, including Black and Hispanic/Latino Americans, as they appear to have higher concentrations of hemoglobin A1c (HbA1c ) than would be predicted by other metrics of mean glycemia...
March 25, 2024: Journal of Diabetes Science and Technology
https://read.qxmd.com/read/38525001/a-case-of-life-threatening-rupture-of-small-renal-angiomyolipoma-with-an-unidentified-intratumoral-aneurysm-during-follow-up
#34
Masashi Tajiri, Tomoyuki Gentsu, Masato Yamaguchi, Koji Sasaki, Eisuke Ueshima, Takuya Okada, Koji Sugimoto, Takamichi Murakami
We report a case of a life-threatening ruptured renal angiomyolipoma (AML) that did not meet the criteria for prophylactic treatment (tumor >4 cm or intratumoral aneurysm >5 mm) during follow-up. A woman in her 70s was followed up for a 2.5-cm AML with a rich vascular component. An intratumoral aneurysm >5 mm was not identified for 2 years. She complained of a sudden abdominal pain with hypotension, and contrast-enhanced computed tomography revealed a retroperitoneal hematoma with contrast media extravasation from an intratumoral aneurysm...
March 1, 2024: Interventional radiology
https://read.qxmd.com/read/38524383/parieto-occipital-scalp-arteriovenous-malformation-with-drainage-into-the-posterior-superior-sagittal-sinus-a-case-report
#35
Kareem Ibraheem, Omar H Salloum, Osama Hroub, Abd Al Rahman Herbawi, Maram Albandak, Hobaib Shawar, Sharif Bassal
This case report presents the unique clinical presentation of an 18-year-old female patient with an 8-year history of a progressively enlarging pulsatile mass in the left parieto-occipital region of her scalp. Remarkably, there was no history of trauma, headache, or other associated neurological deficits. Advanced imaging techniques, including computed tomography angiography and magnetic resonance imaging, revealed a vascular lesion consistent with an arteriovenous malformation beneath the scalp. Notably, the arteriovenous malformation's nidus was primarily supplied by branches of bilateral superficial temporal and occipital arteries, with a more pronounced involvement on the left side...
2024: SAGE Open Medical Case Reports
https://read.qxmd.com/read/38524125/distinct-functional-neutrophil-phenotypes-in-sepsis-patients-correlate-with-disease-severity
#36
JOURNAL ARTICLE
Qingliang Yang, Jordan C Langston, Roman Prosniak, Samantha Pettigrew, Huaqing Zhao, Edwin Perez, Hannah Edelmann, Nadia Mansoor, Carmen Merali, Salim Merali, Nathaniel Marchetti, Balabhaskar Prabhakarpandian, Mohammad F Kiani, Laurie E Kilpatrick
PURPOSE: Sepsis is a clinical syndrome defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis is a highly heterogeneous syndrome with distinct phenotypes that impact immune function and response to infection. To develop targeted therapeutics, immunophenotyping is needed to identify distinct functional phenotypes of immune cells. In this study, we utilized our Organ-on-Chip assay to categorize sepsis patients into distinct phenotypes using patient data, neutrophil functional analysis, and proteomics...
2024: Frontiers in Immunology
https://read.qxmd.com/read/38523956/innovations-in-diabetic-macular-edema-management-a-comprehensive-review-of-automated-quantification-and-anti-vascular-endothelial-growth-factor-intervention
#37
REVIEW
Soumya Sharma, Sachin Daigavane, Pranaykumar Shinde
Diabetic macular edema (DME) poses a significant threat to the vision and quality of life of individuals with diabetes. This comprehensive review explores recent advancements in DME management, focusing on integrating automated quantification techniques and anti-vascular endothelial growth factor (anti-VEGF) interventions. The review begins with an overview of DME, emphasizing its prevalence, impact on diabetic patients, and current challenges in management. It then delves into the potential of automated quantification, leveraging machine learning and artificial intelligence to improve early detection and monitoring...
February 2024: Curēus
https://read.qxmd.com/read/38523720/parry-romberg-syndrome-a-case-report-and-literature-review
#38
Praveen K Sharma, Aadithiyan Sekar, Aashika Parveen Amir, Ajay Lucas Rubben Prabhu
Parry-Romberg syndrome (PRS) is a rare neurocutaneous and craniofacial disorder characterized by progressive hemifacial wasting and atrophy that predominantly affects children and young adults, with an estimated prevalence of 1 in 700,000 individuals. Despite its rarity, PRS poses significant challenges for patients, their families, and healthcare providers due to its unpredictable course and potential functional and aesthetic impairments. The main aim is to provide a comprehensive overview of PRS, encompassing its clinical features, pathogenesis, and management techniques...
June 2024: Radiology Case Reports
https://read.qxmd.com/read/38523692/-caterpillar-sign-in-corpus-callosum-associated-with-curvilinear-pericallosal-lipoma-in-mri-a-case-report
#39
Kazutoshi Konomatsu, Yosuke Kakisaka, Shiho Sato, Takafumi Kubota, Temma Soga, Kazushi Ukishiro, Kazutaka Jin, Shunji Mugikura, Masashi Aoki, Nobukazu Nakasato
Lipoma of the corpus callosum, also known as pericallosal lipoma, is a rare congenital brain abnormality associated with corpus callosum dysgenesis or agenesis. Two morphological types are described: tubulonodular and curvilinear, with the latter being mostly asymptomatic. We present the case of a 30-year-old woman with epilepsy, whose magnetic resonance imaging revealed a "caterpillar sign" in the corpus callosum associated with a curvilinear pericallosal lipoma. The "caterpillar sign" in the corpus callosum showed low signal intensity on magnetization prepared rapid acquisition with gradient echo, high signal on fluid-attenuated inversion recovery, and low on susceptibility-weighted imaging, possibly indicating abnormal blood vessels penetrating from the ventricle to the posterior callosal vein...
May 2024: Radiology Case Reports
https://read.qxmd.com/read/38523367/sirolimus-experience-in-adult-patients-with-vascular-malformations
#40
JOURNAL ARTICLE
Arif Akyildiz, Rashad Ismayilov, Deniz Can Guven, Hasan Cagri Yildirim, Omer Denizhan Tatar, Fatih Kus, Elvin Chalabiyev, Fatma Alev Turker, Omer Dizdar, Suayib Yalcin, Halil Ibrahim Gullu
AIM: Sirolimus, a mammalian target of rapamycin inhibitor, inhibits cell growth and proliferation by controlling ribosome biogenesis and protein synthesis in vascular anomalies and cancers. However, most sirolimus studies on vascular anomalies were conducted in the pediatric population, with limited data in adults. In this study, we assessed the effectiveness and safety of sirolimus in adult patients with vascular malformation, a subtype of vascular anomaly. METHODS: We conducted a retrospective analysis of adult vascular malformation patients aged over 16, treated at Hacettepe University Cancer Institute from January 2013 to September 2022...
March 24, 2024: Vascular
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