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https://www.readbyqxmd.com/read/28092724/the-pediatric-rome-iv-criteria-what-s-new
#1
Ilan J N Koppen, Samuel Nurko, Miguel Saps, Carlo Di Lorenzo, Marc A Benninga
Functional gastrointestinal disorders (FGIDs) are common in children of all ages and comprise of a wide range of conditions related to the gastrointestinal tract that cannot be attributed to structural or biochemical abnormalities. FGIDs are diagnosed according to the symptom-based Rome criteria. Areas covered: In 2016, the revised pediatric Rome IV criteria were published, these revised criteria are discussed in this review article. For the youngest age group (neonates/toddlers), the criteria for infant colic have undergone the most notable revisions...
January 16, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28092661/interactions-between-the-microbiota-immune-and-nervous-systems-in-health-and-disease
#2
REVIEW
Thomas C Fung, Christine A Olson, Elaine Y Hsiao
The diverse collection of microorganisms that inhabit the gastrointestinal tract, collectively called the gut microbiota, profoundly influences many aspects of host physiology, including nutrient metabolism, resistance to infection and immune system development. Studies investigating the gut-brain axis demonstrate a critical role for the gut microbiota in orchestrating brain development and behavior, and the immune system is emerging as an important regulator of these interactions. Intestinal microbes modulate the maturation and function of tissue-resident immune cells in the CNS...
January 16, 2017: Nature Neuroscience
https://www.readbyqxmd.com/read/28091973/mechanisms-on-spasmolytic-and-anti-inflammatory-effects-of-a%C3%A2-herbal-medicinal-product-consisting-of-myrrh-chamomile-flower-and-coffee-charcoal
#3
Cica Vissiennon, Karl-Heinz Goos, Jürgen Arnhold, Karen Nieber
Inflammatory bowel disease or irritable bowel syndrome are chronic gastrointestinal disorders which are associated with a lifelong therapeutic need. The disease results in physical, psychological, and social problems with an impact on partnership, sexuality, education, and career. Thus, the number of patients and health care professionals relying on traditional and complementary medicines and especially phytotherapy for the treatment of these chronic conditions is increasing over recent years. One traditional herbal medicinal product consisting of chamomile flower, myrrh, and coffee charcoal has been widely used in clinical practice within this indication area...
January 13, 2017: Wiener Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28090568/pathophysiology-of-intestinal-na-h-exchange
#4
Michael A Gurney, Daniel Laubitz, Fayez K Ghishan, Pawel R Kiela
Several members of the SLC9A family of Na(+)/H(+) exchangers are expressed in the gut, with varying expression patterns and cellular localization. Not only do they participate in the regulation of basic epithelial cell functions, including control of transepithelial Na(+) absorption, intracellular pH (pH i ), cell volume, and nutrient absorption, but also in cellular proliferation, migration, and apoptosis. Additionally, they modulate the extracellular milieu in order to facilitate other nutrient absorption and to regulate the intestinal microbial microenvironment...
January 2017: Cellular and Molecular Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28090476/correction-middle-east-consensus-statement-on-the-diagnosis-and-management-of-functional-gastrointestinal-disorders-in-12-months-old-infants
#5
Yvan Vandenplas, Muath Abdurrahman Alturaiki, Wafaa Al-Qabandi, Fawaz AlRefaee, Ziad Bassil, Bassam Eid, Ahmed El Beleidy, Ali Ibrahim Almehaidib, Pierre Mouawad, Maroun Sokhn
[This corrects the article on p. 153 in vol. 19, PMID: 27738596.].
December 2016: Pediatric Gastroenterology, Hepatology & Nutrition
https://www.readbyqxmd.com/read/28090466/microbiome-linked-crosstalk-in-the-gastrointestinal-exposome-towards-host-health-and-disease
#6
REVIEW
Yuseok Moon
The gastrointestinal exposome represents the integration of all xenobiotic components and host-derived endogenous components affecting the host health, disease progression and ultimately clinical outcomes during the lifespan. The human gut microbiome as a dynamic exposome of commensalism continuously interacts with other exogenous exposome as well as host sentineling components including the immune and neuroendocrine circuit. The composition and diversity of the microbiome are established on the basis of the luminal environment (physical, chemical and biological exposome) and host surveillance at each part of the gastrointestinal lining...
December 2016: Pediatric Gastroenterology, Hepatology & Nutrition
https://www.readbyqxmd.com/read/28089766/males-with-mecp2-c-terminal-related-atypical-rett-syndromes-and-their-carrier-mothers
#7
Gabriel M Ronen, Lauren I Brady, Mark A Tarnopolsky
BACKGROUND: This communication examines the expanding phenotypes of the MECP2 C-terminal atypical Rett syndromes in males and their affected carrier mothers. DESCRIPTIONS: We describe three males with normal karyotypes who presented with congenital evolving complex neurodevelopmental encephalopathies with multifaceted symptomatology of hypotonia, epilepsy, ataxia, spasticity, movement disorders, behavioral issues, severe intellectual impairment, and communication skills, and a protracted regression phase followed by stabilization...
October 25, 2016: Pediatric Neurology
https://www.readbyqxmd.com/read/28087404/mood-and-anxiety-disorders-precede-development-of-functional-gastrointestinal-disorders-in-patients-but-not-in-the-population
#8
Michael P Jones, Jan Tack, Lukas Van Oudenhove, Marjorie M Walker, Gerald Holtmann, Natasha A Koloski, Nicholas J Talley
BACKGROUND & AIMS: Understanding the interactions between brain and gastrointestinal disorders requires analysis of the order of disease onset. We analyzed data from 2 independent studies to determine the proportion of individuals with diagnoses of functional gastrointestinal disorders (FGIDs) before diagnoses of mood or anxiety disorders (gut to brain), and vice versa (brain to gut). METHODS: We collected data from a retrospective study of 4966 patients diagnosed with a FGID (irritable bowel syndrome, dyspepsia, or constipation) and mood or anxiety disorder at general practices in the United Kingdom (health care seekers) over an average period of 13...
January 10, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28081325/plasma-levels-of-serotonin-gastrointestinal-symptoms-and-sleep-problems-in-children-with-autism
#9
Sorayya Kheirouri, Parinaz Kalejahi, Seyyed Gholamreza Noorazar
BACKGROUND/AIM: Autism is a neurodevelopmental disorder identified with higher frequency of serotonin abnormalities and gastrointestinal (GI) and sleep problems. This study aimed to evaluate the plasma levels of serotonin, GI symptoms, and sleep problems, and their relationship with autism severity in children with autism. MATERIALS AND METHODS: Thirty-five children with autism and 31 healthy subjects were studied. GI problems, sleep disorders, and severity of disorder were assessed...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28081123/yersinia-enterocolitica-a-neglected-cause-of-human-enteric-infections-in-c%C3%A3-te-d-ivoire
#10
Daniel Saraka, Cyril Savin, Stephane Kouassi, Bakary Cissé, Eugène Koffi, Nicolas Cabanel, Sylvie Brémont, Hortense Faye-Kette, Mireille Dosso, Elisabeth Carniel
BACKGROUND: Enteropathogenic Yersinia circulate in the pig reservoir and are the third bacterial cause of human gastrointestinal infections in Europe. In West Africa, reports of human yersiniosis are rare. This study was conducted to determine whether pathogenic Yersinia are circulating in pig farms and are responsible for human infections in the Abidjan District. METHODOLOGY/PRINCIPAL FINDINGS: From June 2012 to December 2013, pig feces were collected monthly in 41 swine farms of the Abidjan district...
January 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28078679/diet-induced-dysmotility-and-neuropathy-in-the-gut-precedes-endotoxemia-and-metabolic-syndrome-the-chicken-and-the-egg-revisited
#11
Yvonne Elikplim Akua Nyavor, Onesmo Begira Balemba
Neuropathy of the enteric nervous system (ENS) is one of the major underlying causes of debilitating gastrointestinal (GI) motility disorders in diabetic patients. This article is protected by copyright. All rights reserved.
January 11, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28077565/mahmi-database-a-comprehensive-metahit-based-resource-for-the-study-of-the-mechanism-of-action-of-the-human-microbiota
#12
Aitor Blanco-Míguez, Alberto Gutiérrez-Jácome, Florentino Fdez-Riverola, Anália Lourenço, Borja Sánchez
The Mechanism of Action of the Human Microbiome (MAHMI) database is a unique resource that provides comprehensive information about the sequence of potential immunomodulatory and antiproliferative peptides encrypted in the proteins produced by the human gut microbiota. Currently, MAHMI database contains over 300 hundred million peptide entries, with detailed information about peptide sequence, sources and potential bioactivity. The reference peptide data section is curated manually by domain experts. The in silico peptide data section is populated automatically through the systematic processing of publicly available exoproteomes of the human microbiome...
2017: Database: the Journal of Biological Databases and Curation
https://www.readbyqxmd.com/read/28075092/diabetes-mellitus-management-of-gastrointestinal-complications
#13
Beth Careyva, Brian Stello
Gastrointestinal disorders are common complications of diabetes mellitus and include gastroparesis, nonalcoholic fatty liver disease, gastroesophageal reflux disease, and chronic diarrhea. Symptoms of gastroparesis include early satiety, postprandial fullness, nausea, vomiting of undigested food, bloating, and abdominal pain. Gastroparesis is diagnosed based on clinical symptoms and a delay in gastric emptying in the absence of mechanical obstruction. Gastric emptying scintigraphy is the preferred diagnostic test...
December 15, 2016: American Family Physician
https://www.readbyqxmd.com/read/28074309/helicobacter-pylori-induced-premature-senescence-of-extragastric-cells-may-contribute-to-chronic-skin-diseases
#14
Anna Lewinska, Maciej Wnuk
Helicobacter pylori, one of the most frequently observed bacterium in the human intestinal flora, has been widely studied since Marshall and Warren documented a link between the presence of H. pylori in the gastrointestinal tract and gastritis and gastric ulcers. Interestingly, H. pylori has also been found in several other epithelial tissues, including the eyes, ears, nose and skin that may have direct or indirect effects on host physiology and may contribute to extragastric diseases, e.g. chronic skin diseases...
January 10, 2017: Biogerontology
https://www.readbyqxmd.com/read/28072952/-rome-%C3%A2-diagnostic-criteria-of-childhood-functional-gastrointestinal-disorders
#15
A Benninga Benninga, Nurko Nurko, Faure Faure
No abstract text is available yet for this article.
January 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28072728/upper-gastrointestinal-symptoms-in-autoimmune-gastritis-a-cross-sectional-study
#16
Marilia Carabotti, Edith Lahner, Gianluca Esposito, Maria Carlotta Sacchi, Carola Severi, Bruno Annibale
Autoimmune gastritis is often suspected for its hematologic findings, and rarely the diagnosis is made for the presence of gastrointestinal symptoms. Aims of this cross-sectional study were to assess in a large cohort of patients affected by autoimmune gastritis the occurrence and the pattern of gastrointestinal symptoms and to evaluate whether symptomatic patients are characterized by specific clinical features.Gastrointestinal symptoms of 379 consecutive autoimmune gastritis patients were systematically assessed and classified following Rome III Criteria...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28072460/psychosocial-interventions-for-recurrent-abdominal-pain-in-childhood
#17
REVIEW
Rebecca A Abbott, Alice E Martin, Tamsin V Newlove-Delgado, Alison Bethel, Joanna Thompson-Coon, Rebecca Whear, Stuart Logan
BACKGROUND: This review supersedes the original Cochrane review first published in 2008 (Huertas-Ceballos 2008).Between 4% and 25% of school-aged children complain of recurrent abdominal pain (RAP) severe enough to interfere with their daily activities. No organic cause for this pain can be found on physical examination or investigation for the majority of such children. Although many children are managed by reassurance and simple measures, a large range of psychosocial interventions involving cognitive and behavioural components have been recommended...
January 10, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28071023/effect-of-food-processing-on-the-physicochemical-properties-of-dietary-fibre
#18
Vasfiye Hazal Ozyurt, Semih Ötles
Products derived from the manufacturing or processing of plant based foods: cereals, fruits, vegetables, as well as algae, are sources of abundant dietary fibre. Diets high in dietary fibre have been associated with the reduced risk of cardiovascular disease, diabetes, hypertension, obesity, and gastrointestinal disorders. These fibre-rich products and byproducts can also fortify foods, increase their dietary fibre content and result in healthy products, low in calories, cholesterol and fat. Traditionally, consumers have chosen foods such as whole grains, fruits and vegetables as sources of dietary fibre...
July 2016: Acta Scientiarum Polonorum. Technologia Alimentaria
https://www.readbyqxmd.com/read/28068460/side-effects-to-antidepressant-treatment-in-patients-with-depression-and-comorbid-panic-disorder
#19
Stewart A Shankman, Stephanie M Gorka, Andrea C Katz, Daniel N Klein, John C Markowitz, Bruce A Arnow, Rachel Manber, Barbara O Rothbaum, Michael E Thase, Alan F Schatzberg, Martin B Keller, Madhukar H Trivedi, James H Kocsis
OBJECTIVE: Side effects to antidepressant medication can affect the efficacy of treatment, but few predictors foretell who experiences side effects and which side effects they experience. This secondary data analysis examined whether depressed patients with comorbid panic disorder were more likely to experience side effects than those without panic disorder. The study also examined whether greater burden of side effects predicted a poorer treatment course for patients with panic disorder than those without panic disorder...
January 3, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28068209/the-role-of-early-life-nutrition-in-the-establishment-of-gastrointestinal-microbial-composition-and-function
#20
Erin C Davis, Mei Wang, Sharon M Donovan
The development of the human infant intestinal microbiota is a sequential process that begins in utero and continues during the first 2 to 3 years of life. Microbial composition and diversity are shaped by host genetics and multiple environmental factors, of which diet is a principal contributor. An understanding of this process is of clinical importance as the microbiota acquired in early life influence gastrointestinal, immune and neural development, and reduced microbial diversity or dysbiosis during infancy is associated with disorders in infancy and later childhood...
January 9, 2017: Gut Microbes
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