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https://www.readbyqxmd.com/read/28735384/influence-of-feeding-inorganic-vanadium-on-growth-performance-endocrine-variables-and-biomarkers-of-bone-health-in-crossbred-calves
#1
Ravi Prakash Pal, Veena Mani, Deepika Tripathi, Rajesh Kumar, Neelam J Kewalramani
The nutritional essentialities of transition element vanadium (V) as micro-nutrient in farm animals have not yet been established, though in rat model, vanadium as vanadate has been reported to exert insulin-mimetic effect and shown to be needed for proper development of bones. The objective of this study was to determine the effect of V supplementation on growth performance, plasma hormones and bone health status in calves. Twenty-four crossbred calves (body weight 72.83 ± 2.5 kg; age 3-9 months) were blocked in four groups and randomly assigned to four treatment groups (n = 6) on body weight and age basis...
July 22, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28733630/plasma-dipeptidyl-peptidase-4-activity-is-associated-with-left-ventricular-systolic-function-in-patients-with-st-segment-elevation-myocardial-infarction
#2
Jing Wei Li, Yun Dai Chen, Yu Qi Liu, Jin Da Wang, Wei Ren Chen, Ying Qian Zhang, Qiang Ma
Plasma dipeptidyl-peptidase-4 activity (DPP4a) is inversely associated with left ventricular function in patients with heart failure (HF) or diabetes. However, the association between DPP4a and left ventricular function in ST-segment elevation myocardial infarction (STEMI) patients has not been reported. We studied this association in 584 consecutive STEMI patients at a tertiary referral center from July 2014 to October 2015. DPP4a and plasma N-terminal prohormone of B-type natriuretic peptide (NT-proBNP) levels were quantified by enzymatic assays...
July 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28733538/the-abnormality-of-thyroid-hormones-in-patients-with-type-a-hepatic-encephalopathy
#3
Lin Wang, Wanyou Yu, Wukui Cao, Wei Lu
Abnormality of thyroid hormones in liver diseases is common, but data is lacking in patients with type A hepatic encephalopathy (HE). The present study was aimed to determine whether there was an abnormality in thyroid hormones among patients with type A HE. We measured the levels of thyroid hormones in 36 acute liver failure (ALF) patients with type A HE and in 29 acute liver injury patients (international normalized ratio, INR ≥ 1.5) without encephalopathy as control. The clinical parameters associated with abnormality of thyroid hormones were evaluated...
June 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/28733284/specific-signatures-of-the-gut-microbiota-and-increased-levels-of-butyrate-in-children-treated-with-fermented-cow-s-milk-containing-heat-killed-lactobacillus-paracasei-cba-l74
#4
Roberto Berni Canani, Francesca De Filippis, Rita Nocerino, Manolo Laiola, Lorella Paparo, Antonio Calignano, Carmen De Caro, Lorena Coretti, Lorenzo Chiariotti, Jack A Gilbert, Danilo Ercolini
We recently demonstrated that cow's milk fermented with the probiotic L.paracasei CBA L74 (FM-CBAL74) reduces the incidence of respiratory and gastrointestinal tract infections in young children attending school. This effect apparently derives from a complex regulation of non-immune and immune protective mechanisms. We investigated wheter FM-CBAL74 could regulate gut microbiota composition and butyrate production.We randomly selected 20 healthy children (12-48 months) from the previous randomized controlled trial, before (t0) and after 3 months (t3) of dietary treatment with FM-CBAL74 (FM), or placebo (PL)...
July 21, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28731315/hypocholesterolemic-activity-of-cornelian-cherry-cornus-mas-l-fruits
#5
Fatemeh Hosseinpour, Tahoora Shomali, Mahmoud Rafieian-Kopaei
Background Lipid profile disturbances are important risk factors for cardiovascular events in patients with diabetes mellitus and finding safe and multifaceted agents is persuaded in this regard. This study aimed to evaluate the effect of cornelian cherry dried powder (CCDP) on serum lipid profile as well as liver antioxidant capacity, HMG-CoA reductase level and activity, and LDL receptor level in streptozotocin-induced diabetic rats. Methods Forty-eight male adult Wistar rats were randomly allocated into eight equal groups and were treated for 4 weeks as follows: negative control (normal rats, basic diet); positive control (diabetic rats, basic diet), T1 to T4 groups: diabetic rats fed with basic diet containing 0...
June 1, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28728405/effect-of-rapeseed-meal-supplementation-to-gestation-diet-on-reproductive-rerformance-blood-profiles-and-milk-composition-of-sows
#6
Hyunbong Choi, Song Shan Jin, Sung Woong Jung, Jae Cheol Jang, Jin Su Hong, Jae Hark Jeong, Y Y Kim
Objective: This experiment was conducted to evaluate the effect of dietary supplementation levels of rapeseed meal (RSM) in gestation diets on reproductive performance, blood profiles and milk composition of sows and performance of their progeny. Methods: A total of 55 mixed-parity sows (Yorkshire × Landrace; average parity = 3.82) with an initial body weight (BW) of 193.0 kg were used in this experiment. Sows were allotted to one of 5 treatments at breeding based on BW and backfat thickness in a completely randomized design...
July 17, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28727982/genome-wide-dna-methylation-profile-of-prepubertal-porcine-testis
#7
Xi Chen, Liu-Hong Shen, Li-Xuan Gui, Fang Yang, Jie Li, Sui-Zhong Cao, Zhi-Cai Zuo, Xiao-Ping Ma, Jun-Liang Deng, Zhi-Hua Ren, Zhong-Xu Chen, Shu-Min Yu
The biological structure and function of the mammalian testis undergo important developmental changes during prepuberty and DNA methylation is dynamically regulated during testis development. In this study, we generated the first genome-wide DNA methylation profile of prepubertal porcine testis using methyl-DNA immunoprecipitation (MeDIP) combined with high-throughput sequencing (MeDIP-seq). Over 190 million high-quality reads were generated, containing 43642 CpG islands. There was an overall downtrend of methylation during development, which was clear in promoter regions but less so in gene-body regions...
July 21, 2017: Reproduction, Fertility, and Development
https://www.readbyqxmd.com/read/28726184/hormetic-effect-of-triiodothyronine-in-metabolically-healthy-obese-persons
#8
Ji Eun Jun, Tae Hyuk Kim, Seung-Eun Lee, You-Bin Lee, Jae Hwan Jee, Ji Cheol Bae, Sang-Man Jin, Kyu Yeon Hur, Jae Hyeon Kim, Sun Wook Kim, Jae Hoon Chung, Yong-Ki Min, Moon-Kyu Lee
PURPOSE: Metabolically healthy obese is the designation for a subgroup of obese individuals with normal metabolic features. However, metabolically healthy obese individuals are prone to developing metabolic syndrome. Serum triiodothyronine (T3) levels are associated with various metabolic risk factors including obesity. Therefore, this longitudinal study aimed to explore the possible correlation between serum T3 concentration and the onset of MetS in metabolically healthy obese persons...
July 19, 2017: Endocrine
https://www.readbyqxmd.com/read/28724410/identification-and-characterization-of-long-non-coding-rnas-in-subcutaneous-adipose-tissue-from-castrated-and-intact-full-sib-pair-huainan-male-pigs
#9
Jing Wang, Liushuai Hua, Junfeng Chen, Jiaqing Zhang, Xianxiao Bai, Binwen Gao, Congjun Li, Zhihai Shi, Weidong Sheng, Yuan Gao, Baosong Xing
BACKGROUND: Long non-coding RNAs (lncRNAs) regulate adipose tissue metabolism, however, their function on testosterone deficiency related obesity in humans is less understood. For this research, intact and castrated male pigs are the best model animal because of their similar proportional organ sizes, cardiovascular systems and metabolic features. RESULTS: We identified lncRNAs in subcutaneous adipose tissue by deep RNA-sequencing using the intact and castrated Huainan male pigs...
July 19, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28723842/reduced-neuromuscular-performance-in-amenorrheic-elite-endurance-athletes
#10
Åsa B Tornberg, Anna Melin, Fiona Manderson Koivula, Anders Johansson, Sven Skouby, Jens Faber, Anders Sjödin
INTRODUCTION: Secondary functional hypothalamic amenorrhea (SFHA) is common among female athletes, especially in weight-sensitive sports. The aim of this study was to investigate the link between SFHA and neuromuscular performance in elite endurance athletes. METHODS: Sixteen eumenorrheic (EUM) and 14 SFHA athletes from national teams and competitive clubs participated. Methods included gynecological examination; body composition (DXA);; resting metabolic rate and work efficiency; exercise capacity; knee muscular strength (KMS) and knee muscular endurance (KME); reaction time (RT); blood sampling performed on the 3rd-5th day of the menstrual cycle, and 7-day assessment of energy availability...
July 19, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28721614/low-doses-of-chlorpyrifos-interfere-with-spermatogenesis-of-rats-through-reduction-of-sex-hormones
#11
Dinithi Champika Peiris, Thamali Dhanushka
Use of pesticides results in indirect effects on human health. We aimed to evaluate implications of toxicological effects of subchronic chlorpyrifos exposure on reproductive function in male rats. A total of 48 adult Wistar male rats were separated into four groups (n = 12). Animals were gavaged with 2.5 mg/kg (T1), 5 mg/kg (T2), or 10 mg/kg (T3) body weight of chlorpyrifos (CPF) or distilled water (control) daily for 30 days. Organ weights, epididymal sperm parameters, DNA integrity, sex hormonal (FHS and LH) levels, and alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyl transferase (GGT), and creatinine concentrations were determined on day 31...
July 18, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28717317/effect-of-season-on-physiological-biochemical-hormonal-and-oxidative-stress-parameters-of-indigenous-sheep
#12
Sawankumar D Rathwa, A A Vasava, M M Pathan, S P Madhira, Y G Patel, A M Pande
AIM: This study was conducted to evaluate the impact of summer and winter season on physiological, biochemical, hormonal, and antioxidant parameters in Indigenous sheep. MATERIALS AND METHODS: The research was carried out during summer and winter season. 8 adult apparently healthy female sheep (aged 2-4 years) of similar physiological status were selected. Daily ambient temperature and relative humidity were recorded to calculate the temperature-humidity index (THI)...
June 2017: Veterinary World
https://www.readbyqxmd.com/read/28713287/vitamin-a-affects-flatfish-development-in-a-thyroid-hormone-signaling-and-metamorphic-stage-dependent-manner
#13
Ignacio Fernández, Juan B Ortiz-Delgado, Maria J Darias, Francisco Hontoria, Karl B Andree, Manuel Manchado, Carmen Sarasquete, Enric Gisbert
Vitamin A (VA) and retinoid derivatives are known morphogens controlling vertebrate development. Despite the research effort conducted during the last decade, the precise mechanism of how VA induces post-natal bone changes, and particularly those operating through crosstalk with the thyroid hormones (THs) remain to be fully understood. Since effects and mechanisms seem to be dose and time-dependent, flatfish are an interesting study model as they undergo a characteristic process of metamorphosis driven by THs that can be followed by external appearance...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28712422/torturing-personification-of-chronic-pain-among-torture-survivors
#14
Noga Tsur, Golan Shahar, Ruth Defrin, Yael Lahav, Karni Ginzburg
BACKGROUND: Consistent with the human tendency to anthropomorphize objects, events, and situations, individuals might ascribe human characteristics to physical symptoms and illnesses. This manuscript presents an examination of chronic pain personification in torture survivors. Specifically, it was hypothesized that torture survivors personify chronic pain as a torturing sensation. It was further hypothesized that PTSD mediates the effect of past torture on torturing pain personification...
August 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28710785/effect-of-thyroid-hormone-on-cardiac-function-following-orthotopic-heart-transplantation-in-piglets
#15
T K Susheel Kumar, Craig Mathis, Shyam Sathanandam, David Zurakowski, Saradha Subramanian, Jerry Allen, Michael Solimine, Lindsay Berrios, Scott Jackson, Mark Landers, Ryan Sullivan, Stacey Barnett, Mark Rayburn, Christopher Loftis, Lauren Price, James B Tansey, Deepthi Hoskoppal, Christopher Knott-Craig
Studies in adult HT have demonstrated improved cardiac function in the recipient following administration of T3 to the donor. The purpose of this experiment was to assess the effects of T3 on the function of the immature donor heart following HT in a piglet model. A total of 32 piglets were divided into 16 donors and 16 recipients. Following creation of brain death, half of the donor piglets were randomized to receive three doses of T3 (0.2 μg/kg) along with hydrocortisone (1 mg/kg). The donor hearts were then transplanted into the recipient piglets on CPB...
July 14, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/28706256/an-extremely-high-dietary-iodide-supply-forestalls-severe-hypothyroidism-in-na-i-symporter-nis-knockout-mice
#16
Giuseppe Ferrandino, Rachel R Kaspari, Andrea Reyna-Neyra, Nabil E Boutagy, Albert J Sinusas, Nancy Carrasco
The sodium/iodide symporter (NIS) mediates active iodide (I(-)) accumulation in the thyroid, the first step in thyroid hormone (TH) biosynthesis. Mutations in the SLC5A5 gene encoding NIS that result in a non-functional protein lead to congenital hypothyroidism due to I(-) transport defect (ITD). ITD is a rare autosomal disorder that, if not treated promptly in infancy, can cause mental retardation, as the TH decrease results in improper development of the nervous system. However, in some patients, hypothyroidism has been ameliorated by unusually large amounts of dietary I(-)...
July 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28702447/effects-of-physical-activity-on-debilitating-behaviours-in-13-to-20-year-old-males-with-severe-autism-spectrum-disorder
#17
Linda Duffy, Bahman Baluch, Sarah Welland, Evren Raman
The presented study investigated the extent to which engaging in a therapeutic sporting programme in males with severe autism spectrum disorder (ASD) improves the debilitating behaviours commonly associated with ASD. Furthermore, the views of parents of the autistic participants were assessed concerning the effectiveness of the programme. Participants were eight 13- to 20-year-old males born in the United Kingdom from a school and sports college for pupils with severe learning difficulties. The selection was using volunteer sampling from the "Monday Club" initiative, run by Saracens Sports Foundation in partnership with a local school and specialist sports college...
June 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/28701285/association-of-divalent-cations-and-insulin-resistance-with-thyroid-hormones-in-patients-with-type-2-diabetes-mellitus
#18
Rajendran Jayanthi, Abu Raghavan Srinivasan, Niranjan Gopal, Ramesh Ramaswamy
AIM: The study was primarily aimed at investigating the association of Magnesium and Zinc levels in the serum of adult Non- obese and Obese type 2 diabetic patients, with particular reference to thyroid comorbidity. METHODS: 108 patients with T2DM of both genders (24 Non obese and 84 Obese) were enrolled from a tertiary health care unit in Puducherry. The cardio-metabolic risk factors were assessed through body mass index, Waist hip ratio, blood pressure, fasting blood glucose, lipid profile and glycated haemoglobin...
July 3, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28699427/treatment-of-swedish-patients-with-graves-hyperthyroidism-is-associated-with-changes-in-acylcarnitine-levels
#19
Mahmoud Al-Majdoub, Mikael Lantz, Peter Spègel
Background Hyperthyroidism is associated with alterations in metabolism that currently are only partially understood. The objective of the study was to investigate changes in metabolism associated with reinstatement of euthyroidism in Swedish patients. Methods We profiled 80 metabolites in plasma from 10 subjects with Graves' disease at baseline and after 9 and 15 month of treatment to reinstate euthyroidism. Thyroid parameters, thyroid stimulating hormone (TSH), TSH receptor antibodies, free T3 and T4 were followed...
July 12, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28697769/a-nurse-delivered-clinic-based-intervention-to-address-intimate-partner-violence-among-low-income-women-in-mexico-city-findings-from-a-cluster-randomized-controlled-trial
#20
Jhumka Gupta, Kathryn L Falb, Oriana Ponta, Ziming Xuan, Paola Abril Campos, Annabel Arellano Gomez, Jimena Valades, Gisele Cariño, Claudia Diaz Olavarrieta
BACKGROUND: Rigorous evaluations of health sector interventions addressing intimate partner violence (IPV) in low- and middle-income countries are lacking. We aimed to assess whether an enhanced nurse-delivered intervention would reduce IPV and improve levels of safety planning behaviors, use of community resources, reproductive coercion, and mental quality of life. METHODS: We randomized 42 public health clinics in Mexico City to treatment or control arms. In treatment clinics, women received the nurse-delivered session (IPV screening, supportive referrals, health/safety risk assessments) at baseline (T1), and a booster counselling session after 3 months (T2)...
July 12, 2017: BMC Medicine
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