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https://www.readbyqxmd.com/read/28823111/welfare-to-work-interventions-and-their-effects-on-the-mental-and-physical-health-of-lone-parents-and-their-children
#1
REVIEW
Marcia Gibson, Hilary Thomson, Kasia Banas, Vittoria Lutje, Martin J McKee, Susan P Martin, Candida Fenton, Clare Bambra, Lyndal Bond
BACKGROUND: Lone parents in high-income countries have high rates of poverty (including in-work poverty) and poor health. Employment requirements for these parents are increasingly common. 'Welfare-to-work' (WtW) interventions involving financial sanctions and incentives, training, childcare subsidies and lifetime limits on benefit receipt have been used to support or mandate employment among lone parents. These and other interventions that affect employment and income may also affect people's health, and it is important to understand the available evidence on these effects in lone parents...
August 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28821377/ischemic-stroke-and-impact-of-thyroid-profile-at-presentation-a-systematic-review-and-meta-analysis-of-observational-studies
#2
Rashmi Dhital, Dilli Ram Poudel, Niranjan Tachamo, Bishal Gyawali, Sijan Basnet, Pragya Shrestha, Paras Karmacharya
BACKGROUND: Stroke is the fifth leading cause of mortality in the United States and a leading cause of disability. A complex relationship between thyroid hormone levels and severity of, and outcome after, stroke has been described. AIM: Our objective is to identify the association between baseline thyroid function profile and outcome after acute ischemic stroke. METHODS: Studies looking at the association between thyroid function and functional stroke outcomes were identified from available electronic databases from inception to December 16, 2016...
August 15, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28821244/the-effect-of-dietary-bacterial-organic-selenium-on-growth-performance-antioxidant-capacity-and-selenoproteins-gene-expression-in-broiler-chickens
#3
A M Dalia, T C Loh, A Q Sazili, M F Jahromi, A A Samsudin
BACKGROUND: Selenium (Se) is an essential trace mineral in broilers, which has several important roles in biological processes. Organic forms of Se are more efficient than inorganic forms and can be produced biologically via Se microbial reduction. Hence, the possibility of using Se-enriched bacteria as feed supplement may provide an interesting source of organic Se, and benefit broiler antioxidant system and other biological processes. The objective of this study was to examine the impacts of inorganic Se and different bacterial organic Se sources on the performance, serum and tissues Se status, antioxidant capacity, and liver mRNA expression of selenoproteins in broilers...
August 18, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28818092/associations-of-thyroid-hormone-serum-levels-with-in-vivo-alzheimer-s-disease-pathologies
#4
Hyo Jung Choi, Min Soo Byun, Dahyun Yi, Bo Kyung Sohn, Jun Ho Lee, Jun-Young Lee, Yu Kyung Kim, Dong Young Lee
BACKGROUND: The present study investigated the relationships between thyroid hormone serum levels or thyroid-stimulating hormone (TSH) and two Alzheimer's disease (AD)-specific biomarkers, cerebral amyloid beta (Aβ) burden and glucose metabolism, in AD-signature brain regions in cognitively normal (CN) middle-aged and older individuals. METHODS: This study assessed 148 CN individuals who received comprehensive clinical and neuropsychological assessments that included (11)C-Pittsburgh Compound B (PiB)-positron emission tomography (PET) scans, (18)F-deoxyglucose (FDG)-PET scans, and the quantification of serum triiodothyronine (T3), free T3, free thyroxine (fT4), and TSH levels...
August 17, 2017: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/28816171/effect-of-magnesium-supplementation-on-muscular-damage-markers-in-basketball-players-during-a-full-season
#5
Alfredo Córdova Martínez, Diego Fernández-Lázaro, Juan Mielgo-Ayuso, Jesús Seco Calvo, Alberto Caballero García
Although it has been widely accepted that Mg has a positive effect on muscle function, studies on the efficacy of Mg supplementation in young athletes have generated contrasting results. The aim of this work was to examine the effect of Mg supplementation on muscular damage markers and the association between serum Mg levels with these muscular markers. Twelve elite male basketball players (PB) from a team of Spanish Professional Basketball League and a control group (CG) comprising twelve university students who practiced regularly recreational basketball and competed in minor university leagues participated in this study...
August 17, 2017: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/28812446/higher-dietary-intake-of-vitamin-d-may-influence-total-cholesterol-and-carbohydrate-profile-independent-of-body-composition-in-men-with-chronic-spinal-cord-injury
#6
Christopher Beal, Ashraf Gorgey, Pamela Moore, Nathan Wong, Robert A Adler, David Gater
STUDY DESIGN: A case-control design. OBJECTIVES: To determine the effects of dietary vitamin D intake on insulin sensitivity (Si), glucose effectiveness (Sg), and lipid profile in individuals with spinal cord injury (SCI). METHODS: 20 male, paraplegic (T3-L1) with chronic (> one year) motor complete SCI (AIS A or B) were recruited. Three-day dietary records were analyzed for dietary vitamin D (calciferol), and participants were assigned to one of two groups, a high vitamin D intake group and a low vitamin D intake group based on the mid-point of vitamin D frequency distribution...
August 16, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28810619/microrna-503-suppresses-cell-proliferation-and-invasion-in-osteosarcoma-via-targeting-insulin-like-growth-factor-1-receptor
#7
Zili Wang, Chenhuang Zheng, Kunqi Jiang, Jinshen He, Xu Cao, Song Wu
MicroRNAs (miRs) are a class of small non-coding RNAs and have key roles in various cancer types. Recently, miR-503 has been reported to act as a tumor suppressor in osteosarcoma. However, the detailed mechanism of the regulatory role of miR-503 in osteosarcoma cell proliferation and invasion has largely remained elusive. The present study found that miR-503 was significantly downregulated in osteosarcoma tissues compared to that in matched adjacent non-tumorous tissues. In addition, the expression of miR-503 in osteosarcoma of T3-T4 stage was significantly lower when compared with that in T1-T2 stage samples...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28809934/long-term-exposure-to-air-pollution-and-the-incidence-of-parkinson-s-disease-a-nested-case-control-study
#8
Chiu-Ying Chen, Hui-Jung Hung, Kuang-Hsi Chang, Chung Y Hsu, Chih-Hsin Muo, Chon-Haw Tsai, Trong-Neng Wu
BACKGROUND: Previous studies revealed that chronic exposure to air pollution can significantly increase the risk of the development of Parkinson's disease (PD), but this relationship is inconclusive as large-scale prospective studies are limited and the results are inconsistent. Therefore, the purpose of this study was to ascertain the adverse health effects of air pollution exposure in a nationwide population using a longitudinal approach. MATERIALS AND METHODS: We conducted a nested case-control study using the National Health Insurance Research Dataset (NHIRD), which consisted of 1,000,000 beneficiaries in the National Health Insurance Program (NHI) in the year 2000 and their medical records from 1995 to 2013 and using public data on air pollution concentrations from monitoring stations across Taiwan released from the Environmental Protection Administration to identify people with ages ≥ 40 years living in areas with monitoring stations during 1995-1999 as study subjects...
2017: PloS One
https://www.readbyqxmd.com/read/28808797/do-carer-s-levels-of-unmet-needs-change-over-time-when-caring-for-patients-diagnosed-with-high-grade-glioma-and-how-are-these-needs-correlated-with-distress
#9
G K B Halkett, E A Lobb, T Shaw, M M Sinclair, L Miller, E Hovey, A K Nowak
PURPOSE: The aim of the current study was to determine how carer needs changed longitudinally and understand associations between unmet needs and distress. METHODS: Family carers of patients with high-grade glioma (HGG) were recruited. Carers completed questionnaires during patients' chemoradiotherapy (T1), 3 months (T2) and 6 months (T3) including the following: the Distress Thermometer, the General Health Questionnaire-12, the Partner and Carer Supportive Care (PCS) Needs Scale and its supplement the Access to Services Needs Scale and the Brain Tumour Specific Supportive Care Needs Scale...
August 14, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28807447/role-of-reactive-oxygen-species-during-low-intensity-pulsed-ultrasound-application-in-mc-3-t3-e1-pre-osteoblast-cell-culture
#10
Harmanpreet Kaur, Arno G Siraki, Hasan Uludağ, Douglas N Dederich, Patrick Flood, Tarek El-Bialy
We evaluated the activation of mitogen-activated protein kinase (MAPK) activation through reactive oxygen species (ROS) by application of low-intensity ultrasound (LIPUS) to MC-3 T3 E1 pre-osteoblasts. The cells were subjected to one LIPUS application for either 10 or 20 min, and the control group was exposed to a sham transducer. For ROS inhibition, 10 μM diphenylene iodonium (DPI) was added to the cells an hour before LIPUS application. Samples were collected 1, 3, 6, 12 and 24 h after LIPUS application, and cells were evaluated for ROS generation, cell viability, gene expression and MAPK activation by immunoblot analyses...
August 11, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28806937/prognostic-value-of-pretreatment-serum-alanine-aminotransferase-aspartate-aminotransferase-alt-ast-ratio-and-gamma-glutamyltransferase-ggt-in-patients-with-esophageal-squamous-cell-carcinoma
#11
Hao Huang, Xue-Ping Wang, Xiao-Hui Li, Hao Chen, Xin Zheng, Jian-Hua Lin, Ting Kang, Lin Zhang, Pei-Song Chen
BACKGROUND: The levels of liver function tests (LFTs) are often used to assess liver injury and non-liver disease-related mortality. In our study, the relationship between pretreatment serum LFTs and overall survival (OS) was evaluated in esophageal squamous cell carcinoma (ESCC) patients. METHODS: Our purpose was to investigate the prognostic value of the preoperative alanine aminotransferase/aspartate aminotransferase (ALT/AST) ratio and gamma glutamyltransferase (GGT) in ESCC patients...
August 14, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28806111/-effectiveness-of-mindfulness-based-cancer-recovery-mbcr-program-among-hungarian-cancer-patients
#12
Magda Rohánszky, Károly Berényi, Dóra Fridrik, Henriette Pusztafalvi
INTRODUCTION AND AIM: Employment of mindfulness-based programs and techniques in the treatment of cancer patients have spread exponentially in the past decade. A large number of studies have proved the effectiveness of the program in the reduction of stress symptoms, depression and anxiety, and the improvement of sleep and mood patterns. The present study was done at Firebird Foundation and examines the effectiveness of the complex, MBCR (mindfulness-based cancer recovery)-based psycho-social intervention in the treatment of cancer patients...
August 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28805160/clinical-implications-of-immunoglobulin-g4-to-graves-ophthalmopathy
#13
Sung Hoon Yu, Jun Goo Kang, Chul Sik Kim, Sung-Hee Ihm, Moon Gi Choi, Hyung Joon Yoo, Seong Jin Lee
BACKGROUND: This study aimed to explore relation of immunoglobulin G4 (IgG4) to clinical and laboratory characteristics of patients newly diagnosed with Graves' disease (GD) without or with Graves' ophthalmopathy (GO), and to analyze association of IgG4 with development and grade of GO in GD patients. METHODS: Sixty-four GD patients and 64 sex- and age-matched euthyroid subjects were enrolled. Serum levels of thyroid hormones, thyroid autoantibodies, immunoglobulin G (IgG) and IgG4 were measured, and ophthalmological and ultrasonographical evaluation was performed...
August 12, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28802802/nodal-stage-migration-and-prognosis-in-anal-cancer-a-systematic-review-meta-regression-and-simulation-study
#14
Hema Sekhar, Marcel Zwahlen, Sven Trelle, Lee Malcomson, Rohit Kochhar, Mark P Saunders, Matthew Sperrin, Marcel van Herk, David Sebag-Montefiore, Matthias Egger, Andrew G Renehan
BACKGROUND: In patients with squamous cell carcinoma of the anus (SCCA), lymph node positivity (LNP) indicates poor prognosis for survival and is central to radiotherapy planning. Over the past three decades, LNP proportion has increased, mainly reflecting enhanced detection with newer imaging modalities; a process known as nodal stage migration. If accompanied by constant T stage distributions, prognosis for both lymph node-positive and lymph node-negative groups may improve without any increase in overall survival for individual patients; a paradox termed the Will Rogers phenomenon...
August 9, 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28801328/cytomegalovirus-related-transverse-myelitis-in-an-immunocompetent-host-a-subacute-onset-of-an-immune-mediated-disease
#15
Xavier Merchan-Del Hierro, Alexandra Halalau
We report a case of transverse myelitis in an immunocompetent host with an atypical long onset of symptoms. A 56-year-old man was admitted to the hospital reporting 5 months of progressive ascending lower extremity weakness and numbness, inability to walk, bowel incontinence,urinary retention and several episodes of nausea and vomiting. MRI showed moderate spinal swelling and multiple hyperintense signal changes on cervical levels C2-C5 and thoracic levels T1-T3. Cerebrospinal fluid (CSF) showed pleocytosis and was positive for anti-cytomegalovirus (CMV) IgG intrathecal antibodies, but the CSF PCR for CMV was negative...
August 11, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28800768/3d-printing-assisted-preoperative-plan-of-pedicle-screw-placement-for-middle-upper-thoracic-trauma-a-cohort-study
#16
Wei Xu, Xuming Zhang, Tie Ke, Hongru Cai, Xiang Gao
BACKGROUND: This study aimed to evaluate the application of 3D printing in assisting preoperative plan of pedicle screw placement for treating middle-upper thoracic trauma. METHODS: A preoperative plan was implemented in seven patients suffering from middle-upper thoracic (T3-T7) trauma between March 2013 and February 2016. In the 3D printing models, entry points of 56 pedicle screws (Magerl method) and 4 important parameters of the pedicle screws were measured, including optimal diameter (ϕ, mm), length (L, mm), inclined angle (α), head-tilting angle (+β), and tail-tilting angle (-β)...
August 11, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28799136/silver-nanoparticles-cause-osmoregulatory-impairment-and-oxidative-stress-in-caspian-kutum-rutilus-kutum-kamensky-1901
#17
Fatemeh F Masouleh, Bagher M Amiri, Alireza Mirvaghefi, Hossein Ghafoori, Steffen S Madsen
Silver nanoparticles (AgNPs) are increasingly used in several industrial and household products because of their antibacterial and antifungal properties. Hence, there is an inevitable risk that these chemicals may end up in aquatic biotopes and have adverse effects on the fauna. In order to assess potential health effects on aquatic organisms, this study evaluated the effects of waterborne AgNP exposure for 7 days on a set of critical stress parameters in juvenile Caspian kutum (Rutilus kutum), an economically important fish in the Caspian Sea...
August 11, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28797983/rationalisation-of-the-irrational-neuropathological-basis-of-hypothyroidism-olfaction-disorders-paradox-experimental-study
#18
Nazan Aydin, Leyla Ramazanoglu, Mehmet Resid Onen, Ilhan Yilmaz, Mehmet Dumlu Aydin, Konca Altinkaynak, Muhammet Calik
OBJECTIVE: Hypothyroidism is defined as an underactive thyroid gland and one of the reasons for inadequate stimulation of thyroid is dysfunction of the hormone regulating brain centers. Olfaction disorders have been considered as a problem in hypothyroidism. It has been hypothesised that olfaction disorders reduce olfactory stimulation and diminished olfactory stimulus may trigger hypothyroidism. In this study an examination was made of the thyroid hormone levels, histological features of thyroid glands and vagal nerve network degradation in an experimental animal model of olfactory bulbectomy (OBX)...
August 7, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28795268/management-of-a-high-thoracic-chance-fracture
#19
Anouar Bourghli, Ibrahim Obeid, Louis Boissiere, Jean-Marc Vital, Zafer Tabboush, Mohammed Al Sarawan
PURPOSE: Chance fracture of the high thoracic spine is rare, and its impact on the adjacent cervical spine can be important. METHODS: We present the case of a 16-year-old male, who fell down from a 2 m height, in an unknown context as he has a mental retardation, and no witness saw the accident. Initial CT scan revealed a comminuted depressed fracture of the right parietal bone, associated with a chance fracture at the level of T3 with a kyphosis and bilateral lung contusion...
August 9, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28791193/spinal-thoracic-extradural-angiolipoma-manifesting-as-acute-onset-of-paraparesis-case-report-and-review-of-literature
#20
Franz Jooji Onishi, Flavio Augusto Sekeff Salem, Diogo Luis de Melo Lins, Rafi Felicio Bauab Dauar, João Norberto Stavale
BACKGROUND: Angiolipomas are benign tumors most commonly found in the thoracic spine. They are composed of mature adipocytes and abnormal vascular elements that usually present with a slowly progressive course of neurological deterioration. CASE DESCRIPTION: A 35-year-old female, with a prior history of back pain, acutely developed paraparesis. When the thoracic magnetic resonance imaging (MRI) revealed a dorsal epidural mass at the T3-T5 level, she underwent a laminectomy for gross total excision of the lesion that proved to be an angiolipoma...
2017: Surgical Neurology International
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