keyword
Keywords Nonobstructive coronary artery...

Nonobstructive coronary artery disease

https://read.qxmd.com/read/38487074/the-importance-of-nontraditional-and-sex-specific-risk-factors-in-young-women-with-vasomotor-nonobstructive-vs-obstructive-coronary-syndromes
#1
JOURNAL ARTICLE
Emilie T Théberge, Diana N Vikulova, Simon N Pimstone, Liam R Brunham, Karin H Humphries, Tara L Sedlak
BACKGROUND: Heart disease is the leading cause of premature death for women in Canada. Ischemic heart disease is categorized as myocardial infarction (MI) with no obstructive coronary artery disease (MINOCA), ischemia with no obstructive coronary arteries (INOCA), and atherosclerotic obstructive coronary artery disease (CAD) with MI (MI-CAD) or without MI (non-MI-CAD). This study aims to study the prevalence of traditional and nontraditional ischemic heart disease risk factors and their relationships with (M)INOCA, compared to MI-CAD and non-MI-CAD in young women...
February 2024: CJC open
https://read.qxmd.com/read/38487045/pathophysiology-of-myocardial-infarction-with-nonobstructive-coronary-artery-disease-a-contemporary-systematic-review
#2
REVIEW
Laurie-Anne Boivin-Proulx, Kevin Haddad, Marco Lombardi, Aun Yeong Chong, Javier Escaned, Swati Mukherjee, Jessica Forcillo, Brian J Potter, Thais Coutinho, Christine Pacheco
BACKGROUND: Myocardial infarction with nonobstructive coronary artery disease (MINOCA) is defined as acute myocardial infarction (AMI) with angiographically nonobstructive coronary artery disease. MINOCA represents 6% of all AMI cases and is associated with increased mortality and morbidity. However, the wide array of pathophysiological factors and causes associated with MINOCA presents a diagnostic conundrum. Therefore, we conducted a contemporary systematic review of the pathophysiology of MINOCA...
February 2024: CJC open
https://read.qxmd.com/read/38477865/impact-of-renal-denervation-on-patients-with-coronary-microvascular-dysfunction-study-rationale-and-design
#3
JOURNAL ARTICLE
Stefano Migliaro, Alessandro Petrolini, Simona Mariani, Fabrizio Tomai
AIMS: Long-standing hypertension may cause an impairment in microvascular coronary circulation, which is involved in many different cardiac conditions. Renal sympathetic denervation (RDN) has been successfully proven as a valuable therapeutic choice for patients with resistant hypertension; moreover, the procedure looks promising in other settings, such as heart failure and atrial fibrillation, given its ability to downregulate the sympathetic nervous system, which is a recognized driver in these conditions as well as in microvascular dysfunction progression...
March 6, 2024: Journal of Cardiovascular Medicine
https://read.qxmd.com/read/38466532/acute-coronary-syndrome-in-women-an-update
#4
REVIEW
Madeleine R Alder, Kylie E Adamek, Angela Lowenstern, Leah M Raj, Kathryn J Lindley, Nadia R Sutton
PURPOSE OF REVIEW: The goal of this manuscript is to provide a concise summary of recent developments in the approach to and treatment of women with acute coronary syndrome (ACS). RECENT FINDINGS: This review covers terminology updates relating to ACS and myocardial injury and infarction. Updates on disparities in recognition, treatments, and outcomes of women with ACS due to atherosclerotic coronary artery disease are covered. Other causes of ACS, including spontaneous coronary artery dissection and myocardial infarction with non-obstructive coronary artery disease are discussed, given the increased frequency in women compared with men...
March 11, 2024: Current Cardiology Reports
https://read.qxmd.com/read/38418054/anoca-and-the-endothelium-a-link-that-can-no-longer-be-ignored
#5
EDITORIAL
Thabo Mahendiran, Bernard De Bruyne
No abstract text is available yet for this article.
February 26, 2024: JACC. Cardiovascular Interventions
https://read.qxmd.com/read/38418053/coronary-vasomotor-dysfunction-is%C3%A2-associated-with-cardiovascular-events-in-patients-with-nonobstructive-coronary%C3%A2-artery-disease
#6
JOURNAL ARTICLE
Yoshihisa Kanaji, Ali Ahmad, Jaskanwal Deep Singh Sara, Ilke Ozcan, Nadia Akhiyat, Abhiram Prasad, Claire E Raphael, Tsunekazu Kakuta, Lilach O Lerman, Amir Lerman
BACKGROUND: Coronary vasomotor dysfunction (CVDys) can be comprehensively classified on the basis of anatomy and functional mechanisms. OBJECTIVES: The aim of this study was to evaluate the association between different CVDys phenotypes and outcomes in patients with angina and nonobstructive coronary artery disease (ANOCA). METHODS: Patients with ANOCA who underwent coronary reactivity testing using an intracoronary Doppler guidewire to assess microvascular and epicardial coronary endothelium-dependent and endothelium-independent function were enrolled...
February 26, 2024: JACC. Cardiovascular Interventions
https://read.qxmd.com/read/38415135/ranolazine-for-improving-coronary-microvascular-function-in-patients-with-nonobstructive-coronary-artery-disease-a-systematic-review-and-meta-analysis-with-a-trial-sequential-analysis-of-randomized-controlled-trials
#7
JOURNAL ARTICLE
Hao Ling, Sunjing Fu, Mengting Xu, Bing Wang, Bingwei Li, Yuan Li, Xueting Liu, Xiaoyan Zhang, Qin Wang, Ailing Li, Mingming Liu
BACKGROUND: Microvascular dysfunction in patients with nonobstructive coronary artery disease is increasingly being recognized as an important health issue. This systematic review and meta-analysis evaluated the effectiveness of ranolazine, an antianginal agent, in improving coronary microvascular function. METHODS: We conducted a comprehensive literature search of the Cochrane Library, PubMed, Embase, China National Knowledge Infrastructure, the Chinese BioMedical Literature Database, and gray literature databases until September 30, 2023...
February 1, 2024: Quantitative Imaging in Medicine and Surgery
https://read.qxmd.com/read/38385055/myocardial-infarction-with-nonobstructive-coronaries-minoca-following-rabies-postexposure-prophylaxis-a-case-report
#8
Reechashree Dhungana, Prajjwal Pokharel, Chandra Mani Poudel, Raja Ram Khanal, Smriti Shakya, Ratna Mani Gajurel
KEY CLINICAL MESSAGE: This case underscores the importance of considering myocardial infarction with nonobstructive coronary arteries (MINOCA) in patients experiencing acute chest pain following rabies vaccination, emphasizing the need for heightened awareness and further research into the association between MINOCA and Rabies vaccination. ABSTRACT: Rabies is a vaccine-preventable deadly viral disease prevalent in Asia and Africa that causes thousands of deaths annually...
February 2024: Clinical Case Reports
https://read.qxmd.com/read/38346669/innervation-of-the-coronary-arteries-and-its-role-in-controlling-microvascular-resistance
#9
REVIEW
Takanori Sato, Peter Hanna, Shumpei Mori
The coronary circulation plays a crucial role in balancing myocardial perfusion and oxygen demand to prevent myocardial ischemia. Extravascular compressive forces, coronary perfusion pressure, and microvascular resistance are involved to regulate coronary blood flow throughout the cardiac cycle. Autoregulation of the coronary blood flow through dynamic adjustment of microvascular resistance is maintained by complex interactions among mechanical, endothelial, metabolic, neural, and hormonal mechanisms. This review focuses on the neural mechanism...
February 10, 2024: Journal of Cardiology
https://read.qxmd.com/read/38320905/the-importance-of-nonobstructive-plaque-characteristics-in-symptomatic-and-asymptomatic-coronary-artery-disease
#10
JOURNAL ARTICLE
Martina C de Knegt, Jesper J Linde, Per E Sigvardsen, Thomas Engstrøm, Andreas Fuchs, Andreas K Jensen, Hanne Elming, J Tobias Kühl, Peter R Hansen, Dan E Høfsten, Henning Kelbæk, Børge G Nordestgaard, Jens D Hove, Lars V Køber, Klaus F Kofoed
BACKGROUND: We examined obstructive and nonobstructive plaque volumes in populations with subclinical and clinically manifested coronary artery disease (CAD) using quantitative computed tomography (QCT). METHODS: 855 participants with CAD (274 asymptomatic individuals, 254 acute chest pain patients without acute coronary syndrome (ACS), and 327 patients with ACS) underwent QCT of proximal coronary segments to assess participant-level plaque volumes of dense calcium, fibrous, fibrofatty, and necrotic core tissue...
February 5, 2024: Journal of Cardiovascular Computed Tomography
https://read.qxmd.com/read/38308909/establishment-of-nonobstructive-coronary-microcirculatory-disorders-in-rabbits-using-three-established-methods-and-a-comparative-study
#11
JOURNAL ARTICLE
Jia-Xin Zhao, Guo-Dong Wang, Li-Na Guan, Yu-Ming Mu
To compare the merits and drawbacks of three approaches for establishing a rabbit model of nonobstructive coronary microcirculatory disease, namely, open thoracic subtotal ligation of coronary arteries, ultrasound-guided cardiac microsphere injection, and sodium laurate injection. New Zealand rabbits were allocated to four groups: a normal group (Blank group), an Open-chest group (Open-chest), a microsphere group (Echo-M), and a sodium laurate group (Echo-SL), each comprising 10 rabbits. The rabbits were sacrificed 24 h after the procedures, and their echocardiography, stress myocardial contrast echocardiography, pathology, and surgical times were compared...
January 19, 2024: Biochemical and Biophysical Research Communications
https://read.qxmd.com/read/38305146/prognostic-role-of-coronary-artery-ectasia-in-patients-with-nonobstructive-coronary-artery-disease
#12
JOURNAL ARTICLE
Filippo Luca Gurgoglione, Giorgio Benatti, Luigi Vignali, Iacopo Tadonio, Giulia Magnani, Andrea Denegri, Davide Lazzeroni, Domenico Tuttolomondo, Mattia De Gregorio, Elia Indrigo, Gianluca Signoretta, Vittoria Abbati, Francesco Nicolini, Diego Ardissino, Emilia Solinas, Giampaolo Niccoli
AIMS: Coronary artery ectasia (CAE) has been linked to the occurrence of adverse events in patients with ischemia/angina and no obstructive coronary arteries (INOCA/ANOCA), while the relationship between CAE and myocardial infarction with nonobstructive coronary arteries (MINOCA) has been poorly investigated. In our study we aimed at assessing differences in clinical, angiographic and prognostic features among patients with CAE and MINOCA vs. INOCA/ANOCA presentation. METHODS: Patients with angiographic evidence of CAE were enrolled at the University Hospital of Parma and divided into MINOCA vs...
January 31, 2024: Journal of Cardiovascular Medicine
https://read.qxmd.com/read/38299358/coronary-microvascular-dysfunction-is-associated-with-a-proinflammatory-circulating-transcriptome-in-patients-with-nonobstructive-coronary-arteries
#13
JOURNAL ARTICLE
Nathaniel R Smilowitz, Florencia Schlamp, Anaïs Hausvater, Amanda Joa, Claudia Serrano-Gomez, Ayman Farid, Judith S Hochman, Tessa Barrett, Harmony R Reynolds, Jeffrey S Berger
No abstract text is available yet for this article.
February 1, 2024: Arteriosclerosis, Thrombosis, and Vascular Biology
https://read.qxmd.com/read/38274903/carmustine-induced-takotsubo-cardiomyopathy
#14
Muhammad Z Khan, Muhammad Waqas, Hadia Shah, Sona Franklin, Ayesha Jamil
Carmustine is an intravenous alkylating agent that inhibits DNA synthesis and protein synthesis by forming cross-links in DNA and RNA and ultimately causing cell death. We report a rare case of Takotsubo cardiomyopathy that is thought to be related to carmustine, where the patient presented with chest pain, and ST depression within 12 hours of carmustine therapy. Workup, including echocardiography, showed global hypokinesis of the left ventricle with regional variations; mid and apical anterior septum and apex were akinetic with left ventricular ejection fraction (EF) of 30%...
December 2023: Curēus
https://read.qxmd.com/read/38274622/different-characteristics-and-interleukin-6-ratios-of-scattering-type-aortic-plaques
#15
JOURNAL ARTICLE
Sei Komatsu, Chikao Yutani, Satoru Takahashi, Tomoki Ohara, Nobuzo Iwa, Mitsuhiko Takewa, Hirotaka Noda, Kazuhisa Kodama
Background Cholesterol crystals (CCs) are related to innate inflammation in spontaneously ruptured aortic plaques (SRAPs), and variability exists in the CCs and interleukin (IL)-6 ratio in SRAPs. Methods The prevalence of scattering-type ruptures that glittered against the light of angioscopic fibers (puff-chandelier ruptures) and those that did not (puff ruptures) was analyzed in 848 patients with suspected coronary artery disease. Overall, 177 puff-chandelier ruptures and 105 puff ruptures were sampled using nonobstructive general angioscopy (NOGA)...
January 2024: Curēus
https://read.qxmd.com/read/38245257/role-of-nuclear-cardiology-in-diagnosis-and-risk-stratification-of-coronary-microvascular-disease
#16
REVIEW
Terrence D Ruddy, Anahita Tavoosi, Viviany R Taqueti
Coronary flow reserve (CFR) with positron emission tomography/computed tomography (PET/CT) has an important role in the diagnosis of coronary microvascular disease (CMD), aids risk stratification and may be useful in monitoring therapy. CMD contributes to symptoms and a worse prognosis in patients with coronary artery disease (CAD), nonischemic cardiomyopathies, and heart failure. CFR measurements may improve our understanding of the role of CMD in symptoms and prognosis in CAD and other cardiovascular diseases...
August 2023: Journal of Nuclear Cardiology
https://read.qxmd.com/read/38243161/triglyceride-glucose-body-mass-index-as-a-novel-predictor-of-slow-coronary-flow-phenomenon-in-patients-with-ischemia-and-nonobstructive-coronary-arteries-inoca
#17
JOURNAL ARTICLE
Zhi-Peng Li, Juan Chen, Qi Xin, Xiao-Yang Pei, Hong-Li Wu, Zhi-Xu Tan
BACKGROUND: The triglyceride glucose-body mass index (TyG-BMI index) has been suggested as a novel predictor of insulin resistance. However, its predictive value for slow coronary flow phenomenon (SCFP) in patients with ischemia and nonobstructive coronary arteries (INOCA) remains unclear. METHODS: We consecutively recruited 1625 patients with INOCA from February 2019 to February 2023 and divided them into two groups based on thrombolysis in myocardial infarction (TIMI) frame counts (TFCs): the SCFP group (n = 79) and the control group...
January 19, 2024: BMC Cardiovascular Disorders
https://read.qxmd.com/read/38232023/men-with-nonobstructive-coronary-disease-have-higher-burden-of-ischemic-heart-disease-detected-by-cardiopulmonary-exercise-test
#18
JOURNAL ARTICLE
Siyuan Li, Yifang Yuan, Lanting Zhao, Tingting Lv, Fei She, Fang Liu, Yajun Xue, Boda Zhou, Ying Xie, Yu Geng, Ping Zhang
BACKGROUND: Nonobstructive coronary artery disease (NOCAD), characterized by the presence of myocardial ischemic symptoms and signs without obstructive coronaries, is a common clinical condition, but it is less well understood. Few studies have analyzed the gender differences in inducible myocardial ischemia assessed by cardiopulmonary exercise test (CPET) in NOCAD. METHODS: We conducted a study of 289 NOCAD patients (mean age 60, 56% women) with ischemic symptoms and confirmed ⫹50% coronaries stenoses by coronary angiography who underwent symptom-limited CPET...
February 2024: Microcirculation: the Official Journal of the Microcirculatory Society, Inc
https://read.qxmd.com/read/38229310/andrographolide-protect-against-lipopolysacharides-induced-vascular-endothelium-dysfunction-by-abrogation-of-oxidative-stress-and-chronic-inflammation-in-sprague-dawley-rats
#19
JOURNAL ARTICLE
Debiprasad Padhy, Satyam Sharma, Sanjiv Singh
The development of heart disease involves interconnected factors such as oxidative stress, inflammation, and vascular dysfunction. Andrographolide (AG), known for its potent antioxidant and anti-inflammatory properties, has the potential to counteract lipopolysaccharides (LPS)-induced endothelial dysfunction by reducing oxidative stress and inflammation. Our research aimed to investigate the effects of AG on alleviating vascular endothelium dysfunction, oxidative stress, and inflammation in an experimental model induced by LPS...
January 2024: Journal of Biochemical and Molecular Toxicology
https://read.qxmd.com/read/38199706/rethinking-false-positive-exercise-electrocardiographic-stress-tests%C3%A2-by%C3%A2-assessing-coronary-microvascular-function
#20
JOURNAL ARTICLE
Aish Sinha, Utkarsh Dutta, Ozan M Demir, Kalpa De Silva, Howard Ellis, Samuel Belford, Mark Ogden, Matthew Li Kam Wa, Holly P Morgan, Ajay M Shah, Amedeo Chiribiri, Andrew J Webb, Michael Marber, Haseeb Rahman, Divaka Perera
BACKGROUND: Exercise electrocardiographic stress testing (EST) has historically been validated against the demonstration of obstructive coronary artery disease. However, myocardial ischemia can occur because of coronary microvascular dysfunction (CMD) in the absence of obstructive coronary artery disease. OBJECTIVES: The aim of this study was to assess the specificity of EST to detect an ischemic substrate against the reference standard of coronary endothelium-independent and endothelium-dependent microvascular function in patients with angina with nonobstructive coronary arteries (ANOCA)...
January 16, 2024: Journal of the American College of Cardiology
keyword
keyword
115637
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.