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https://www.readbyqxmd.com/read/29468771/home-blood-pressure-monitoring-in-a-hypertensive-pregnant-population
#1
H Perry, E Sheehan, B Thilaganathan, A Khalil
OBJECTIVE: The majority of patients with chronic or gestational hypertension do not develop pre-eclampsia. Home blood-pressure monitoring (HBPM) has the potential to offer a more accurate and acceptable means of monitoring hypertensive patients during pregnancy compared with traditional pathways of frequent outpatient monitoring. The aim of this study was to determine whether HBPM reduces visits to antenatal services and is safe in pregnancy. METHODS: This was a case-control study of 166 hypertensive pregnant women, which took place at St George's Hospital, University of London...
February 22, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29456580/the-accuracy-of-ultrasound-estimation-of-fetal-weight-in-comparison-to-birth-weight-a-systematic-review
#2
Julia Milner, Jane Arezina
Ultrasound estimation of fetal weight is a highly influential factor in antenatal management, guiding both the timing and mode of delivery of a pregnancy. Although substantial research has investigated the most accurate ultrasound formula for calculating estimated fetal weight, current evidence indicates significant error levels. The aim of this systematic review was to identify the most accurate method, whilst identifying sources of inaccuracy in order to facilitate recommendations for future practice. Seven studies met the inclusion criteria and 11 different formulae were assessed; ultrasound calculation of fetal weight was most commonly overestimated...
February 2018: Ultrasound: Journal of the British Medical Ultrasound Society
https://www.readbyqxmd.com/read/29455616/is-the-fetal-cerebroplacental-ratio-better-that-the-estimated-fetal-weight-in-predicting-adverse-perinatal-outcomes-in-a-low-risk-cohort
#3
Christopher Flatley, Sailesh Kumar
OBJECTIVE: In high-risk pregnancies combining the cerebro-placental ratio (CPR) with the estimated fetal weight (EFW) improves the identification of vulnerable fetuses. The purpose of this study was to assess the CPR and EFW's ability to predict adverse obstetric and perinatal outcomes in a low-risk pregnancy, when measured late in gestation. METHODS: This was a retrospective study of women who birthed at Mater Mothers Hospitals, Brisbane, Australia between 2010 and 2015...
February 18, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29455594/vaginal-birth-after-a-cesarean-delivery-for-arrest-of-descent
#4
Nathan S Fox, Amalia G Namath, Munira Ali, Mariam Naqvi, Simi Gupta, Andrei Rebarber
OBJECTIVE: To determine vaginal birth after cesarean (VBAC) success rates for patients with a prior cesarean delivery (CD) for arrest of descent, as well as determine any predictors for success. STUDY DESIGN: This was a retrospective cohort study of all patients delivered by a single MFM practice from 2005-2017 with a singleton pregnancy and one prior CD for arrest of descent. We estimated the rate and associated risk factors for successful VBAC. RESULTS: We included 208 patients with one prior CD for arrest of descent, 100 (48...
February 18, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29455122/benzotriazoles-and-benzothiazoles-in-paired-maternal-urine-and-amniotic-fluid-samples-from-tianjin-china
#5
Xiaoying Li, Lei Wang, Alexandros G Asimakopoulos, Hongwen Sun, Zhen Zhao, Junjie Zhang, Lu Zhang, Qi Wang
Benzotriazoles (BTRs) and benzothiazoles (BTHs) are two groups of heterocyclic compounds that are widely detected in the environment. In this study, the levels of BTRs and BTHs in 79 paired maternal urine and amniotic fluid samples from Tianjin were investigated. BTRs were detected in most maternal urine samples, with a median concentration of ∑BTRs of 0.88 ng/mL. BTH was detected in all maternal urine samples, with a median concentration of 1.35 ng/mL. Tolyltriazole (TTR, i.e., the sum of 4-methyl-1H-benzotriazole and 5-methyl-1H-benzotriazole) and BTH were detected in amniotic fluid with detection rates (DRs) > 50% and median concentrations of 0...
February 12, 2018: Chemosphere
https://www.readbyqxmd.com/read/29449665/prediction-of-vaginal-birth-after-cesarean-delivery-in-chinese-parturients
#6
Juan Wen, Xuejing Song, Hongjuan Ding, Xiaofeng Shen, Rong Shen, Ling-Qun Hu, Wei Long
There is an urgent need in China to better predict vaginal birth after cesarean (VBAC) to face the challenge of the second child policy. We aimed to validate a widely used VBAC prediction model (Grobman's model) and a modified version of this model in a Chinese population. In this retrospective cohort study, 444 women with one cesarean delivery and at least one subsequent attempt for a trial of labor in Nanjing, China were included. The considered potential VBAC predictors included Grobman's background variables and five new variables...
February 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29447050/added-value-of-cerebro-placental-ratio-and-uterine-artery-doppler-at-routine-third-trimester-screening-as-a-predictor-of-sga-and-fgr-in-nonselected-pregnancies
#7
M Rial-Crestelo, R J Martinez-Portilla, A Cancemi, J Caradeux, L Fernandez, A Peguero, E Gratacos, Francesc Figueras
OBJECTIVES: To determine the added value of cerebroplacental ratio (CPR) and uterine Doppler velocimetry at third trimester scan in an unselected obstetric population to predict smallness and growth restriction. METHODS: We constructed a prospective cohort study of women with singleton pregnancies attended for routine third trimester screening (32 +0 -34 +6 weeks). Fetal biometry and fetal-maternal Doppler ultrasound examinations were performed by certified sonographers...
February 15, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29445311/fetal-growth-restriction-in-rural-bangladesh-a-prospective-study
#8
Farzana Ferdous, Md Harunor Rashid, Enbo Ma, Rubhana Raqib, Hiromi Hamada, Yukiko Wagatsuma
Background: Fetal growth restriction (FGR) and low birth weight(LBW) are serious public health problems. In developing countries, the incidence of low birth weight is predominantly the result of FGR, and both low birth weight and FGR are associated with neonatal death and later growth and development. Fetal growth charts are important for assessing the size of the fetus during pregnancy. The aims of this study were to describe the fetal growth pattern of a population in rural Bangladesh where maternal undernutrition is prevalent and to compare the timing of FGR in that population with WHO and INTERGROWTH- 21st international reference values...
2018: Tropical Medicine and Health
https://www.readbyqxmd.com/read/29439623/aspirin-ameliorates-preeclampsia-induced-by-a-peroxisome-proliferator-activated-receptor-antagonist
#9
Chunhua Zhang, Yong Zhu, Yan Shen, Changting Zuo
Reduced expression of peroxisome proliferator-activated receptor γ (PPARγ) in the placenta was found in women with severe preeclampsia. Aspirin is currently used as the only recommended intervention in pregnancies for prevention of preeclampsia. In this study, we aimed to investigate whether aspirin could attenuate PPARγ inhibitor (T0070907)-induced preeclampsia and its impact on expression of PPARγ. Sixty Sprague-Dawley rats were used and treated with different doses of aspirin (0, 1, and 1.5 mg/kg) in presence or absence of PPARγ antagonist, T0070907...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29422212/diagnosis-and-surveillance-of-late-onset-fetal-growth-restriction
#10
REVIEW
Francesc Figueras, Javier Caradeux, Fatima Crispi, Elisenda Eixarch, Anna Peguero, Eduard Gratacos
By consensus, late fetal growth restriction is that diagnosed >32 weeks. This condition is mildly associated with a higher risk of perinatal hypoxic events and suboptimal neurodevelopment. Histologically, it is characterized by the presence of uteroplacental vascular lesions (especially infarcts), although the incidence of such lesions is lower than in preterm fetal growth restriction. Screening procedures for fetal growth restriction need to identify small babies and then differentiate between those who are healthy and those who are pathologically small...
February 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29422209/fetal-growth-velocity-and-body-proportion-in-the-assessment-of-growth
#11
REVIEW
Liran Hiersch, Nir Melamed
Fetal growth restriction implies failure of a fetus to meet its growth potential and is associated with increased perinatal mortality and morbidity. Therefore, antenatal detection of fetal growth restriction is of major importance in an attempt to deliver improved clinical outcomes. The most commonly used approach towards screening for fetal growth restriction is by means of sonographic fetal weight estimation, to detect fetuses small for gestational age, defined by an estimated fetal weight <10th percentile for gestational age...
February 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29422207/a-new-customized-fetal-growth-standard-for-african-american-women-the-prb-nichd-detroit-study
#12
Adi L Tarca, Roberto Romero, Dereje W Gudicha, Offer Erez, Edgar Hernandez-Andrade, Lami Yeo, Gaurav Bhatti, Percy Pacora, Eli Maymon, Sonia S Hassan
BACKGROUND: The assessment of fetal growth disorders requires a standard. Current nomograms for the assessment of fetal growth in African American women have been derived either from neonatal (rather than fetal) biometry data or have not been customized for maternal ethnicity, weight, height, and parity and fetal sex. OBJECTIVE: We sought to (1) develop a new customized fetal growth standard for African American mothers; and (2) compare such a standard to 3 existing standards for the classification of fetuses as small (SGA) or large (LGA) for gestational age...
February 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29422206/individualized-growth-assessment-conceptual-framework-and-practical-implementation-for-the-evaluation-of-fetal-growth-and-neonatal-growth-outcome
#13
REVIEW
Russell L Deter, Wesley Lee, Lami Yeo, Offer Erez, Uma Ramamurthy, Medha Naik, Roberto Romero
Fetal growth abnormalities can pose significant consequences on perinatal morbidity and mortality of nonanomalous fetuses. The most widely accepted definition of fetal growth restriction is an estimated fetal weight less than the 10th percentile for gestational age according to population-based criteria. However, these criteria do not account for the growth potential of an individual fetus, nor do they effectively separate constitutionally small fetuses from ones that are malnourished. Furthermore, conventional approaches typically evaluate estimated fetal weight at a single time point, rather than using serial scans, to evaluate growth...
February 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29422204/the-world-health-organization-fetal-growth-charts-concept-findings-interpretation-and-application
#14
REVIEW
Torvid Kiserud, Alexandra Benachi, Kurt Hecher, Rogelio González Perez, José Carvalho, Gilda Piaggio, Lawrence D Platt
Ultrasound biometry is an important clinical tool for the identification, monitoring, and management of fetal growth restriction and development of macrosomia. This is even truer in populations in which perinatal morbidity and mortality rates are high, which is a reason that much effort is put onto making the technique available everywhere, including low-income societies. Until recently, however, commonly used reference ranges were based on single populations largely from industrialized countries. Thus, the World Health Organization prioritized the establishment of fetal growth charts for international use...
February 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29415594/maternal-obesity-is-not-associated-with-increased-crown-rump-length-in-first-trimester-ultrasounds-of-singleton-gestations
#15
Geoffrey H Gordon, Kathleen M Antony, Emmanuel Sampene, Jesus Igor Iruretagoyena
OBJECTIVE: To evaluate whether or not obesity affects fetal growth in the first trimester of pregnancy. STUDY DESIGN: A retrospective cohort study of obese versus nonobese women in our ultrasound database was performed to compare crown-rump length (CRL), a surrogate of fetal growth, at the first-trimester genetic screening. RESULTS: A total of 50 obese and 50 nonobese women were included. CRL for both groups was performed at an average of 12wk5d ± 3 d...
February 7, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29407903/effects-of-maternal-undernutrition-on-the-growth-development-and-antioxidant-status-of-ovine-placentome-subtypes-during-late-pregnancy
#16
Yingchun Liu, Hui Li, Qila Sha, Rihan Hai, Ying Wang, Yanfeng Song, Feng Gao
This study investigated the effects of maternal undernutrition on the growth, development and antioxidant status of ovine placentome subtypes during late pregnancy. Eighteen time-mated Mongolian ewes with singleton fetuses were allocated to three groups at d 90 of pregnancy: Restricted Group 1 (RG1, 0.18 MJ ME · kg BW-0.75 · d-1, n = 6), Restricted Group 2 (RG2, 0.33 MJ ME · kg BW-0.75 · d-1, n = 6) and Control Group (CG, ad libitum, 0.67 MJ ME · kg BW -0.75 · d -1, n = 6). All animals were supplied chopped hay during the restriction period...
January 11, 2018: Theriogenology
https://www.readbyqxmd.com/read/29401269/chronic-hyperandrogenemia-and-western-style-diet-beginning-at-puberty-reduces-fertility-and-increases-metabolic-dysfunction-during-pregnancy-in-young-adult-female-macaques
#17
C V Bishop, R L Stouffer, D L Takahashi, E C Mishler, M C Wilcox, O D Slayden, C A True
STUDY QUESTION: What are the impacts of elevated testosterone (T) and an obesogenic western-style diet (WSD), either independently or together, on fertility and metabolic adaptations of pregnancy in primates? SUMMARY ANSWER: Testosterone increases the time to achieve pregnancy, while a WSD reduces overall fertility, and the combination of testosterone and WSD additionally impairs glucose tolerance and causes pregnancy loss. WHAT IS KNOWN ALREADY: Both hyperandrogenemia and obesity are hallmarks of polycystic ovary syndrome, which is a leading cause of infertility among women worldwide...
February 1, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29400112/risk-of-neonatal-care-unit-admission-in-small-for-gestational-age-fetuses-at-term-a-prediction-model-and-internal-validation
#18
Erkan Kalafat, Jose Morales-Rosello, Basky Thilaganathan, Jasreen Dhother, Asma Khalil
OBJECTIVE: Small for gestational age (SGA) fetuses are at increased risk of admission to the neonatal unit, even at term. We aimed to develop and validate a predictive model for the risk of prolonged neonatal unit admission in suspected SGA fetuses at term. METHODS: A single-center cohort study of singleton pregnancies with SGA fetus, defined as estimated fetal weight (EFW) less than the 10th centile, at term. The variables included known risk factors for neonatal unit admissions: maternal characteristics, EFW, abdominal circumference (AC), fetal Dopplers, gestational age (GA) at delivery, and intrapartum risk factors (meconium, pyrexia)...
February 4, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29385271/prescriptive-birth-weight-charts-can-improve-the-prediction-of-adverse-outcomes-in-very-preterm-infants-who-are-small-for-gestational-age
#19
Liset Hoftiezer, Renske G Snijders, Chantal W P M Hukkelhoven, Richard A van Lingen, Marije Hogeveen
AIM: We compared three anthropometric charts to determine which provided the best predictions for adverse outcomes in very preterm small for gestational age infants to address a lack of consensus on this subject. METHODS: This was a retrospective cohort study of infants born below 32 weeks, who were admitted to two level three neonatal intensive care units in The Netherlands from 2008-2013. The birth weights of 1,720 infants were classified as SGA using: a conventional, gender-specific birth weight chart, based on births in The Netherlands between 2000-2007, a prescriptive, gender-specific birth weight chart, based on the same data but without risk factors for intrauterine growth restrictions, and a non-gender-specific fetal weight chart derived from American ultrasonographic measurements...
January 31, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29381473/low-dose-aspirin-for-preventing-fetal-growth-restriction-a-randomised-trial
#20
Anca-Daniela Stanescu, Roxana Banica, Romina-Marina Sima, Liana Ples
The purpose of this study was to investigate when in pregnancy to stop the administration of low dose aspirin (150 mg/daily) so as to prevent fetal growth restriction (FGR) A randomised, placebo-controlled study was designed. The patients were all screened positive using the Fetal Medicine Foundation (FMF) early pregnancy screening test for preeclampsia (PE) and FGR prediction. One hundred and fifty patients were enrolled and divided equally into three groups: A - the controls who received placebo treatment; B - those who received aspirin till 32 weeks of gestation and C - those who received aspirin till 36 weeks of gestation...
January 30, 2018: Journal of Perinatal Medicine
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