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spontanous bacterial peritonitis

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https://www.readbyqxmd.com/read/29675988/dose-dependent-impact-of-proton-pump-inhibitors-on-the-clinical-course-of-spontaneous-bacterial-peritonitis
#1
Tammo L Tergast, Anika Wranke, Hans Laser, Svetlana Gerbel, Michael P Manns, Markus Cornberg, Benjamin Maasoumy
BACKGROUND & AIMS: Spontaneous bacterial peritonitis (SBP) is a severe complication in patients with liver cirrhosis leading to acute kidney injury (AKI), hepatic encephalopathy (HE) and a high mortality. In this study we aimed to investigate the impact of proton pump inhibitors (PPI) and the potential relevance of the taken dosage on the incidence and clinical course of SBP. METHODS: Overall, 613 consecutive patients with decompensated liver cirrhosis were included...
April 19, 2018: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/29629510/endoscopic-ultrasound-guided-coil-or-glue-injection-in-post-cyanoacrylate-gastric-variceal-re-bleed
#2
Roy J Mukkada, Rajesh Antony, Mathew J Chooracken, Jose V Francis, Antony P Chettupuzha, Pradeep G Mathew, Philip Augustine, Abraham Koshy
BACKGROUND AND AIMS: N-butyl-cyanoacrylate injection is recommended in bleeding/recently bled gastric varices. However, cyanoacrylate injection is associated with re-bleed in 25% to 50% of patients. Endoscopic ultrasound (EUS)-guided coil application is an emerging treatment modality for bleeding gastric varices. The aim of this study was to compare EUS-guided coil application combined with or without cyanoacrylate glue injection to injection alone in post-glue gastric variceal re-bleed...
April 9, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29589197/spontaneous-bacteremia-and-spontaneous-bacterial-peritonitis-in-cirrhosis-two-infections-but-similar-outcomes
#3
EDITORIAL
Rakhi Maiwall
No abstract text is available yet for this article.
March 27, 2018: Hepatology International
https://www.readbyqxmd.com/read/29579872/therapy-with-direct-acting-antiviral-agents-for-hepatitis-c-in-liver-transplant-recipients
#4
F Nogueras López, A López Garrido, E J Ortega Suazo, F Vadillo Calles, F Valverde López, M D Espinosa Aguilar
BACKGROUND: Recurrent infection with the hepatitis C virus (HCV) after liver transplantation (LT) is associated with decreased graft and patient survival. Direct-acting antiviral (DAA) therapies have changed the landscape of HCV due to their excellent safety profile and cure rates. Our aim was to evaluate the efficacy and tolerability of antiviral therapy in recurrent HCV after LT with DAA therapy. METHODS: Our retrospective analysis included 46 LT recipients with HCV recurrence...
March 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29563694/purtscher-like-retinopathy-a-rare-ocular-finding-in-nephrotic-syndrome
#5
Anamika Dwivedi, Deepak Dwivedi, Charudutt Chalisgaonkar, Sujata Lakhtakia
In this report, we present a case of Purtscher-like retinopathy in a 12-year-old male child with nephrotic syndrome. He was a known case of steroid-dependent nephrotic syndrome, frequent relapser with spontaneous bacterial peritonitis, who presented with complaints of difficulty in vision in both eyes. The fundus examination showed multiple cotton-wool spots and Purtscher fleckens centered around the optic nerve head with superficial retinal hemorrhages in both eyes. Fluorescein angiography confirmed the diagnosis of Purtscher-like retinopathy...
January 2018: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/29561972/impact-of-microbiological-changes-on-spontaneous-bacterial-peritonitis-in-three-different-periods-over-17-years
#6
Paulo Roberto Lerias de Almeida, Gabriel Stefani Leão, Charlles David Gonçalves Gonçalves, Rafael Veiga Picon, Cristiane Valle Tovo
BACKGROUND: Spontaneous bacterial peritonitis is a serious complication in cirrhotic patients, and changes in the microbiological characteristics reported in the last years are impacting the choice of antibiotic used for treatment. OBJECTIVE: The aim of the present study is to evaluate the changes in the epidemiology and bacterial resistance of the germs causing spontaneous bacterial peritonitis over three different periods over 17 years. METHODS: All cirrhotic patients with spontaneous bacterial peritonitis and positive culture of ascites fluid were retrospectively studied in a reference Hospital in Southern Brazil...
January 2018: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/29542304/follow-up-creatinine-level-is-an-important-predictive-factor-of-in-hospital-mortality-in-cirrhotic-patients-with-spontaneous-bacterial-peritonitis
#7
Baek Gyu Jun, Woong Cheul Lee, Jae Young Jang, Soung Won Jeong, Young Don Kim, Gab Jin Cheon, Yun Nah Lee, Sang Gyune Kim, Young Seok Kim, Young Sin Cho, Sae Hwan Lee, Hong Soo Kim
BACKGROUND: Spontaneous bacterial peritonitis (SBP) is one of the severe complications of liver cirrhosis. Early detection of high-risk patients is essential for prognostic improvement. The aim of this study is to investigate the predictive factors related to in-hospital mortality in patients with SBP. METHODS: This was a retrospective study of 233 SBP patients (181 males, 52 females) who were admitted to four tertiary referral hospitals between August 2002 and February 2013...
March 19, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29528017/budd-chiari-syndrome-diagnosed-in-a-patient-listed-for-liver-transplant-and-considered-to-be-contraindicated-for-the-operation
#8
Kakharman Yesmembetov, Zhansaya Muratova, Sergey Borovskiy, Irina Ten, Kulpash Kaliaskarova
We report the clinical case of 23-year-old patient with liver cirrhosis of unknown genesis, significant resistant ascites, and 2 episodes of bleeding from esophageal varices. Evaluation did not find any cause of liver disease, and the patient was placed on the transplant wait list due to subcompensated liver function (Model for End-Stage Liver Disease score of 16, Child-Pugh class B) and poorly controlled severe portal hypertension. After treatment with diuretics, largevolume paracentesis, antibiotics, and vasoconstrictors, hepatorenal syndrome and spontaneous bacterial peritonitis resolved and liver function improved significantly...
March 2018: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/29527261/spontaneous-bacterial-and-fungal-peritonitis-in-patients-with-liver-cirrhosis-a-literature-review
#9
REVIEW
Toru Shizuma
Spontaneous bacterial (SBP) and spontaneous fungal peritonitis (SFP) can be a life-threatening infection in patients with liver cirrhosis (LC) and ascites. One of the possible mechanisms of developing SBP is bacterial translocation. Although the number of polymorphonuclear cells in the culture of ascitic fluid is diagnostic for SBP, secondary bacterial peritonitis is necessary to exclude. The severity of underlying liver dysfunction is predictive of developing SBP; moreover, renal impairment and infections caused by multidrug-resistant (MDR) organism are associated with a fatal prognosis of SBP...
February 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29521663/predicting-mortality-in-patients-with-spontaneous-bacterial-peritonitis-using-routine-inflammatory-and-biochemical-markers
#10
Raim Iliaz, Tahsin Ozpolat, Bulent Baran, Kadir Demir, Sabahattin Kaymakoglu, Fatih Besisik, Filiz Akyuz
OBJECTIVES: Spontaneous bacterial peritonitis (SBP) is a common and high-mortality infectious complication of patients with cirrhosis. New inflammatory markers are associated with morbidity/mortality in various diseases. The aim of our study was to find the 30-day mortality rate of SBP and their predictors. PATIENTS AND METHODS: Seventy patients with cirrhosis complicated with SBP and 55 non-SBP controls were enrolled into the study, and patients were evaluated for mortality rate and its predictors...
March 8, 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29505476/homocysteine-a-new-diagnostic-marker-in-spontaneous-bacterial-peritonitis
#11
Ahmed Abdel-Razik, Waleed Eldars, Rania Elhelaly, Ahmed A Eldeeb, Mostafa Abdelsalam, Niveen El-Wakeel, Alsaid Aboulmagd
BACKGROUND AND AIMS: The diagnosis of spontaneous bacterial peritonitis (SBP) depends primarily on a polymorphonuclear leukocyte cell count more than 250/mm. This method is invasive, and not diagnostic in all variants of SBP; we aimed to assess serum homocysteine as a precise indicative marker for the diagnosis of all variants of SBP. PATIENTS AND METHODS: A total 323 consecutive ascitic patients were registered in this prospective work. Serum and ascitic fluid of homocysteine were evaluated utilizing an enzyme-linked immunosorbent assay...
March 2, 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29503228/early-linezolid-associated-lactic-acidosis-in-a-patient-with-child-s-class-c-liver-cirrhosis-and-end-stage-renal-disease
#12
Chih-Ning Cheng, Shu-Wen Lin, Chien-Chih Wu
Linezolid, an oxazolidinone antibiotic, does not required dose adjustment in patients with Child's class A and B liver cirrhosis. The dose adjustment data for Child's class C liver cirrhosis is inadequate. We reported a case of Child's class C liver cirrhosis, in which lactic acidosis, an adverse effect related to prolonged use, occurred only after two weeks of linezolid treatment. A 63-year old male had underlying diseases, such as end-stage renal disease (ESRD) and Child's class C liver cirrhosis, and was admitted for hepatic encephalopathy management and liver transplantation evaluation...
March 1, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29502362/clinical-impact-of-healthcare-associated-acquisition-in-cirrhotic-patients-with-community-onset-spontaneous-bacterial-peritonitis
#13
Jungok Kim, Cheol-In Kang, Geum-Youn Gwak, Doo Ryeon Chung, Kyong Ran Peck, Jae-Hoon Song
Background/Aims: Healthcare-associated (HCA) infection is a recently suggested new category of community-onset infections. The implications of HCA infections in terms of diagnosis, treatment, and outcomes of spontaneous bacterial peritonitis (SBP) are not well understood. We sought to delineate the differences between community-acquired (CA) SBP and HCA SBP with specific interest in the antimicrobial resistance of causative microorganisms and outcomes. Methods: We conducted a retrospective cohort study of all SBP episodes with positive ascitic culture and/or blood culture from June 2000 to August 2011...
March 5, 2018: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29480417/mortality-from-spontaneous-bacterial-peritonitis-among-hospitalized-patients-in-the-usa
#14
Bolin Niu, Brian Kim, Berkeley N Limketkai, Jing Sun, Zhiping Li, Tinsay Woreta, Po-Hung Chen
BACKGROUND AND AIM: Spontaneous bacterial peritonitis (SBP) is a serious complication of cirrhosis and is associated with significant morbidity and mortality. In this study, we examined the clinical characteristics and risk factors associated with mortality in hospitalized patients presenting with SBP. METHODS: The Nationwide Inpatient Sample was queried for all hospitalizations involving SBP from 2006 to 2014 using the International Classification of Disease-9-CM Code...
February 26, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29452544/can-combined-blood-neutrophil-to-lymphocyte-ratio-and-c-reactive-protein-be-used-for-diagnosis-of-spontaneous-bacterial-peritonitis
#15
N Mousa, T Besheer, A Abdel-Razik, M Hamed, A G Deiab, T Sheta, W Eldars
BACKGROUND AND OBJECTIVE: Spontaneous bacterial peritonitis (SBP) is diagnosed by the presence of ≥250 polymorphonuclear neutrophils (PMN)/mm3 in the ascites and the absence of surgically treatable cause of intra-abdominal infection. Blood neutrophil lymphocytic ratio (NLR) is an inexpensive and simple test for inflammation. C-reactive protein (CRP) is an inflammatory marker used for the diagnosis and follow-up of many diseases and morbidities. We aimed to evaluate the clinical utility of combined blood NLR and CRP as a non-invasive test for SBP diagnosis...
April 2018: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/29429754/spontaneous-bacterial-peritonitis-due-to-helicobacter-pylori-in-a-cirrhotic-patient-with-human-immunodeficiency-virus-and-hepatitis-c-virus-coinfection
#16
Ledicia Álvarez Paredes, Luis Buzón Martín, María Ortega Lafont, Miguel Ángel Morán Rodríguez
No abstract text is available yet for this article.
February 8, 2018: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/29411667/prognosis-of-patients-with-ascites-after-pleurx-insertion-an-observational-study
#17
Agnete Nordheim Riedel, Nina Kimer, Lise Hobolth, Lise Lotte Gluud
OBJECTIVE: To evaluate the safety of PleurX in cirrhotic patients with refractory ascites. METHODS: We prospectively registered patients who received a PleurX catheter cirrhosis-associated refractory ascites at our department from July 2015 to November 2016. Our control group consisted of matched cirrhotic patients with refractory ascites treated with large volume paracentesis (LVP) and patients with malignant ascites treated with PleurX during the same period. RESULTS: We included 25 patients with cirrhosis-related ascites (7 in PleurX group) and 17 with malignant ascites (14 in PleurX group)...
March 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29399286/toll-like-receptor-4-polymorphisms-and-bacterial-infections-in-patients-with-cirrhosis-and-ascites
#18
Edilmar Alvarado-Tapias, Carlos Guarner-Argente, Elida Oblitas, Elisabet Sánchez, Silvia Vidal, Eva Román, Mar Concepción, Maria Poca, Cristina Gely, Oana Pavel, Juan Camilo Nieto, Cándido Juárez, Carlos Guarner, Germán Soriano
AIM: To assess the relationship between the presence of toll-like receptor 4 (TLR4) polymorphisms and bacterial infections in cirrhotic patients with ascites. METHODS: We prospectively included consecutive patients with cirrhosis and ascites hospitalized during a 6-year period. Patients with human immunodeficiency virus (HIV) infection or any other immunodeficiency, patients with advanced hepatocellular carcinoma (beyond Milan's criteria) or any other condition determining poor short-term prognosis, and patients with a permanent urinary catheter were excluded...
January 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29384797/clarifying-the-role-of-c-reactive-protein-as-a-bacterial-infection-predictor-in-decompensated-cirrhosis
#19
David N Perdigoto, Pedro N Figueiredo, Luís F Tomé
INTRODUCTION: Bacterial infections are frequent in cirrhosis and may induce other deleterious complications. Ultrasensitive C-reactive protein (US-CRP), like other acute-phase proteins, is often considered useful in predicting bacterial infection in decompensated cirrhosis. However, US-CRP's reliability remains inconclusive, as inflammation in cirrhosis causes US-CRP synthesis independently of infection. The aim of this study was to clarify US-CRP's role as an infection predictor in decompensated cirrhosis...
January 30, 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29383775/diagnostic-validity-of-flow-cytometry-vs-manual-counting-of-polymorphonuclear-leukocytes-in-spontaneous-bacterial-peritonitis
#20
Heba Ahmed Osman, Sanaa Shaker Aly, Eman M Salah-Eldin, Muhammad Abbas El-Masry, Mohammed H Hassan
BACKGROUND: Spontaneous bacterial peritonitis (SBP) is frequently occurring infection among patients with liver cirrhosis, defined by polymorphonuclear (PMN) leukocytic count ≥250 cell/mm3 with or without a positive ascitic fluid (AF) bacterial culture. So, this study aimed to investigate the diagnostic value of flow cytometry versus manual counting of ascitic fluid PMNL in cirrhotic patients, with clinical suspicion of SBP. METHODS: A hospital-based cross-sectional study was carried out on 320 cirrhotic patients with clinical suspicion of SBP...
January 31, 2018: Journal of Clinical Laboratory Analysis
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