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https://www.readbyqxmd.com/read/29137499/improving-care-and-lowering-costs-evidence-and-lessons-from-a-global-analysis-of-accountable-care-reforms
#1
Mark McClellan, Krishna Udayakumar, Andrea Thoumi, Jonathan Gonzalez-Smith, Kushal Kadakia, Natalia Kurek, Mariam Abdulmalik, Ara W Darzi
Policy makers and providers are under increasing pressure to find innovative approaches to achieving better health outcomes as efficiently as possible. Accountable care, which holds providers accountable for results rather than specific services, is emerging in many countries to support such care innovations. However, these reforms are challenging and complex to implement, requiring significant policy and delivery changes. Despite global interest, the evidence on how to implement accountable care successfully remains limited...
November 2017: Health Affairs
https://www.readbyqxmd.com/read/29136777/anti-hypertensive-and-vasodilatory-effects-of-amended-banxia-baizhu-tianma-tang
#2
Chu Shan Tan, Yean Chun Loh, Chiew Hoong Ng, Yung Sing Ch'ng, Mohd Zaini Asmawi, Mariam Ahmad, Mun Fei Yam
Although Banxia Baizhu Tianma Tang (BBT) has been long administered for hypertensive treatment in Traditional Chinese Medicine (TCM), the ratio of the herbal components that makes up the formulation has not been optimized with respect to the anti-hypertensive effect that it inherently possesses. A newly amended BBT (ABBT) formulation was developed using the evidence-based approach of orthogonal stimulus-response compatibility model. The ABBT showed enhanced therapeutic effect while maintaining its traditional theoretical approach rooted in TCM...
November 7, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29136615/videokymographic-visualization-of-phonasthenia-a-nonorganic-voice-disorder
#3
Mariam Salah Shadi, Mona A Hegazi, Jilan F Nassar, Samia Bassiouny, Sally Sarwat, Marwa M Saleh
BACKGROUND: Phonasthenia is a voice disorder where the larynx looks essentially normal and dysphonia is not heard but felt by the patient. This study aims to use videokymography (VKG) to detect any abnormalities in the vibratory pattern in phonasthenia and to find out whether or not these abnormalities change after vocal loading. METHODS: Thirty-seven phonasthenic patients and 31 normal subjects participated in a detailed protocol, including analysis of subjective complaints and videokymographic quasi-objective parameters (baseline) followed by loading their voices through prolonged loud reading for 45 min...
November 14, 2017: Folia Phoniatrica et Logopaedica
https://www.readbyqxmd.com/read/29132496/relationship-issues-and-high-divorce-rate-among-surgeons
#4
Ahsan Zil-E-Ali, Mariam Tariq Awana, Muhammad Aadil
No abstract text is available yet for this article.
November 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29131822/impact-of-the-ebola-outbreak-on-trypanosoma-brucei-gambiense-infection-medical-activities-in-coastal-guinea-2014-2015-a-retrospective-analysis-from-the-guinean-national-human-african-trypanosomiasis-control-program
#5
Mariame Camara, Eric Ouattara, Alexandre Duvignaud, René Migliani, Oumou Camara, Mamadou Leno, Philippe Solano, Bruno Bucheton, Mamadou Camara, Denis Malvy
BACKGROUND: The 2014-2015 Ebola outbreak massively hit Guinea. The coastal districts of Boffa, Dubreka and Forecariah, three major foci of Human African Trypanosomiasis (HAT), were particularly affected. We aimed to assess the impact of this epidemic on sleeping sickness screening and caring activities. METHODOLOGY/PRINCIPAL FINDINGS: We used preexisting data from the Guinean sleeping sickness control program, collected between 2012 and 2015. We described monthly: the number of persons (i) screened actively; (ii) or passively; (iii) treated for HAT; (iv) attending post-treatment follow-up visits...
November 13, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29130170/fluorescence-quenching-studies-of-%C3%AE-butyrolactone-binding-protein-cprb-from-streptomyces-coelicolor-a3-2
#6
Jessy Mariam, Ruchi Anand
Fluorescence spectroscopy is an important analytical tool which is widely employed to study biological systems. This technique can be applied to qualitatively and quantitatively probe protein-ligand interactions primarily because of its sensitivity, selectivity, nondestructive and rapid form of analysis. In this chapter we describe the utility of this technique to establish a label-free, universal screening protocol for putative γ-butyrolactone (GBL) receptors by exploiting the intrinsic fluorescence of a highly conserved tryptophan residue that constitutes the hydrophobic pocket for GBL binding, a unique feature possessed by this family of receptors...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29129159/third-trimester-ultrasound-accuracy-and-delivery-outcome-in-obese-and-morbid-obese-pregnant-women
#7
Sawsan Al-Obaidly, Abdullah Al-Ibrahim, Najah Saleh, Mariam Al-Belushi, Zeena Al-Mansouri, Najat Khenyab
OBJECTIVE: Several studies have highlighted the negative impact of maternal obesity on ultrasound accuracy for fetal weight estimation (EFW). However, the evidence is conflicting. We aimed in our study to find if the ultrasound accuracy for fetal weight estimation would differ or decrease in obese and morbid obesity classes. In addition to study the mode of delivery within the same cohort. METHODS: It's a retrospective study of obese patients with recorded BMI ≥ 30 kg/m(2), class I and II (BMI 30-39...
November 12, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29123638/panoramic-radiographs-for-detecting-osteopenia-a-pilot-study
#8
Vivek Velayudhan Nair, Sunila Thomas, Jincy Thomas, Cucoo Mariam Mathew
No abstract text is available yet for this article.
September 15, 2017: Clinics and Practice
https://www.readbyqxmd.com/read/29114147/malaria-induced-anaemia-and-serum-micronutrients-in-asymptomatic-plasmodium-falciparum-infected-patients
#9
Babamale O Abdulkareem, Abdulkareem O Adam, Akande O Ahmed, Afolayan A Mariam, Ugbomoiko U Samuel
Interaction between malaria, anaemia and malnutrition is poorly understood in asymptomatic malaria patients. This information is important in the management of malaria infection in many endemic regions in sub-Saharan Africa. Malaria parasitaemia, full blood counts and serum levels of essential micronutrients particularly iron (Fe), zinc (Zn) and copper (Cu) of the patients attending Health Centres in Ilorin, Kwara state were investigated using microscope, auto-haemanalyzer and atomic absorption spectrophotometer respectively...
December 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/29113573/peculiarities-of-interaction-of-synthetic-polyribonucleotide-poly-ra-poly-ru-with-some-intercalators
#10
Poghos O Vardevanyan, Ara P Antonyan, Marine A Parsadanyan, Mariam A Shahinyan, Victoria G Sahakyan
No abstract text is available yet for this article.
November 7, 2017: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/29110886/the-incidence-of-primary-vs-secondary-focal-segmental-glomerulosclerosis-a-clinicopathologic-study
#11
Musab S Hommos, An S De Vriese, Mariam P Alexander, Sanjeev Sethi, Lisa Vaughan, Ladan Zand, Kharmen Bharucha, Nicola Lepori, Andrew D Rule, Fernando C Fervenza
OBJECTIVES: To describe the change in the incidence rates of primary and secondary focal segmental glomerulosclerosis (FSGS) from 1994 through 2013 in Olmsted County, Minnesota, and to identify the clinical and biopsy characteristics that distinguish primary from secondary FSGS. PATIENTS AND METHODS: Olmsted County adult residents with native kidney biopsy from January 1, 1994, through December 31, 2013, and FSGS as the only glomerulopathy were identified. The clinical and pathologic characterstics of primary and secondary FSGS were described and compared, and incidence rates were calculated...
October 27, 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/29110560/the-job-content-context-and-requirements-of-regulated-home-based-childcare-workers
#12
Mariam Stitou, Ivy-Lynn Bourgeault, Dafna Kohen
Contrary to a large and growing literature on center-based childcare workers, we know little about the work and health experiences of those providing childcare services in their homes. This study examines the job content, context, and requirements of regulated Home-Based Childcare workers in Canada. It is based on the qualitative analysis of eleven individual semistructured interviews. These workers perform business administration tasks and more housekeeping and domestic work than those in the center-based childcare, which affect their health and well-being...
January 1, 2017: New Solutions: a Journal of Environmental and Occupational Health Policy: NS
https://www.readbyqxmd.com/read/29100722/measurement-of-the-electron-capture-probabilities-of-55-fe-with-a-metallic-magnetic-calorimeter
#13
M Loidl, M Rodrigues, R Mariam
The ratios of the electron capture probabilities PK, PL and PM of (55)Fe have been measured with a metallic magnetic calorimeter, a specific type of cryogenic detector. The (55)Fe source was enclosed in the detector absorber, whose dimensions were chosen such that the detection efficiency for Mn K X-rays was larger than 99.99%. Since all electrons and photons emitted by the source are absorbed in the detector, the detection efficiency is virtually 100% for K, L and M captures. The energy threshold was low enough to allow for clear separation of the M captures (~ 80eV) from noise...
October 31, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/29100134/the-impact-of-trauma-exposure-characteristics-on-post-traumatic-stress-disorder-and-psychiatric-co-morbidity-among-syrian-refugees
#14
Man Cheung Chung, Nowf AlQarni, Mariam AlMazrouei, Shamsa Al Muhairi, Mudar Shakra, Britt Mitchell, Sara Al Mazrouei, Shurooq Al Hashimi
This study investigated the impact of trauma exposure characteristics on post-traumatic stress disorder (PTSD) and psychiatric co-morbidity among Syrian refugees. One thousand one hundred and ninety-seven refugees residing in Turkey and Sweden participated in the research. They completed the Harvard Trauma Questionnaire and the General Health Questionnaire-28. Forty-three percent of refugees met the cutoff for PTSD. After adjusting for location of residence, witnessing horror and exposure to life threat and assault were significantly correlated with PTSD and psychiatric co-morbidity respectively...
October 25, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29097623/dnaj-heat-shock-protein-family-b-member-9-is-a-novel-biomarker-for-fibrillary-gn
#15
Surendra Dasari, Mariam P Alexander, Julie A Vrana, Jason D Theis, John R Mills, Vivian Negron, Sanjeev Sethi, Angela Dispenzieri, W Edward Highsmith, Samih H Nasr, Paul J Kurtin
Fibrillary GN (FGN) is a rare primary glomerular disease. Histologic and histochemical features of FGN overlap with those of other glomerular diseases, and no unique histologic biomarkers for diagnosing FGN have been identified. We analyzed the proteomic content of glomeruli in patient biopsy specimens and detected DnaJ heat shock protein family (Hsp40) member B9 (DNAJB9) as the fourth most abundant protein in FGN glomeruli. Compared with amyloidosis glomeruli, FGN glomeruli exhibited a >6-fold overexpression of DNAJB9 protein...
November 2, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/29096163/safety-at-the-william-quarrier-scottish-epilepsy-centre
#16
James Anderson, Victoria Grant, Mariam Elgammal, Alison Campbell, Julia Hampshire, Stig Hansen, Aline J C Russell
PURPOSE: We examined the yield from EMFIT bed alarms and staff response time to generalised seizure in a medium term residential assessment unit for epilepsy. METHODS: The Scottish Epilpesy Centre (SEC) has a Video Observation System (VOS) that provides continuous recording of all patient spaces (external and internal) and allows retention of clinically relevant events. A retrospective audit of daily EMFIT test records, nursing seizure record sheets (seizure type and EMFIT alert status), clinical incident reporting systems and the VOS database of retained clinical events was conducted for an 9 month period from April 1st 2016 till December 31st 2016...
October 16, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29090935/discovery-of-the-membrane-binding-domain-in-trifunctional-proline-utilization-a
#17
Shelbi Christgen, Weidong Zhu, Nikhilesh Sanyal, Bushra Mariam Bibi, John J Tanner, Donald Frederick Becker
Escherichia coli proline utilization A (EcPutA) is the archetype of trifunctional PutA flavoproteins, which function both as regulators of the proline utilization operon and bifunctional enzymes that catalyze the four-electron oxidation of proline to glutamate. EcPutA shifts from a self-regulating transcriptional repressor to a bifunctional enzyme in a process known as functional switching. The flavin redox state dictates the function EcPutA. Upon proline oxidation, the flavin becomes reduced, triggering a conformational change that causes EcPutA to dissociate from the put regulon and bind to the cellular membrane...
November 1, 2017: Biochemistry
https://www.readbyqxmd.com/read/29090008/automated-flow-cytometry-an-alternative-to-urine-culture-in-a-routine-clinical-microbiology-laboratory
#18
REVIEW
Patricia Mejuto, Mariam Luengo, Julio Díaz-Gigante
The urine culture is the "gold standard" for the diagnosis of urinary tract infections (UTI) but constitutes a significant workload in the routine clinical laboratory. Due to the high percentage of negative results, there is a need for an efficient screening method, with a high negative predictive value (NPV) that could reduce the number of unnecessary culture tests. With the purpose of improving the efficiency of laboratory work, several methods for screening out the culture-negative samples have been developed, but none of them has shown adequate sensitivity (SE) and high NPV...
2017: International Journal of Microbiology
https://www.readbyqxmd.com/read/29084362/the-impact-of-conventional-and-nonconventional-inhalants-on-children-and-adolescents
#19
Samya Z Nasr, Ali Ibrahim Nasrallah, Mariam Abdulghani, Stuart C Sweet
AIM: Inhalant abuse in the adolescent population is a growing concern for care givers, communities, physicians, and medical providers. The aim of this article is to provide a review of the literature about this new challenge. In addition, it raises awareness about recent health policy rulings. METHODS: Review of the literature was done. RESULTS: In this review article, the prevalence of different modes of inhalant use and abuse in children and young adults and their potential health implications will be examined: Cigarettes, ENDS (E Cigarettes), Hookah, Marijuana, and Huffing...
October 30, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29082047/protein-c-deficiency-caused-by-a-novel-mutation-in-the-proc-gene-in-an-infant-with-delayed-onset-purpura-fulminans
#20
Mariam S Al Harbi, Ayman W El-Hattab
Protein C is an anticoagulant that is encoded by the PROC gene. Protein C deficiency (PCD) is inherited in an autosomal dominant or recessive pattern. Autosomal dominant PCD is caused by monoallelic mutations in PROC and often presents with venous thromboembolism. On the other hand, biallelic PROC mutations lead to autosomal recessive PCD which is a more severe disease that typically presents in neonates as purpura fulminans. In this report, we describe an 8-month-old infant with autosomal recessive PCD who presented with multiple lumps on his lower extremities at the age of 2 months and later developed purpura fulminans after obtaining a muscle biopsy from the thigh at the age of 5 months...
2017: Case Reports in Dermatological Medicine
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