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https://www.readbyqxmd.com/read/28633858/effects-of-processing-parameters-in-the-sonic-assisted-water-extraction-sawe-of-6-gingerol
#1
Syaripah Zaimah Syed Jaapar, Noor Azian Morad, Yoshio Iwai, Mariam Firdhaus Mad Nordin
The use of water in subcritical conditions for extraction has several drawbacks. These include the safety features, higher production costs and possible degradation of the bioactive compounds. To overcome these problems, sonic energy and an entrainer were used as external interventions to decrease the polarity of water at milder operating conditions. The effect of low (28kHz) and high (800kHz) frequencies of sonication in the extraction of the main ginger bioactive compound (6-gingerol) were compared. Six parameters were studied: mean particle size (MPS, mm), time of extraction, applied power, sample to solvent ratio (w/v), temperature of extraction, and the percentage of entrainer...
September 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28632491/lessons-learned-on-health-adaptation-to-climate-variability-and-change-experiences-across-low-and-middle-income-countries
#2
Kristie L Ebi, Mariam Otmani Del Barrio
BACKGROUND: There is limited published evidence of the effectiveness of adaptation in managing the health risks of climate variability and change in low- and middle-income countries. OBJECTIVES: To document lessons learned and good practice examples from health adaptation pilot projects in low- and middle-income countries to facilitate assessing and overcoming barriers to implementation and to scaling up. METHODS: We evaluated project reports and related materials from the first five years of implementation (2008-2013) of multinational health adaptation projects in Albania, Barbados, Bhutan, China, Fiji, Jordan, Kazakhstan, Kenya, Kyrgyzstan, Philippines, Russian Federation, Tajikistan, and Uzbekistan...
June 20, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28632434/screening-for-celiac-disease-by-endomysial-antibodies-in-patients-with-unexplained-hypertransaminasaemia
#3
Mariam Ghozzi, Mohamed Ali Ben Salem, Fatma Mbarki, Ali Jmaa, Azza Baccouch, Nabil Sakly, Elhem Ben Jazia, Ibtissem Ghedira
OBJECTIVE: To do a serological screening for celiac disease in patients with unexplained liver cytolysis. MATERIALS AND METHODS: Fifty-six patients with liver cytolysis without known aetiology were studied. Endomysial antibodies were determined by indirect immunofluorescence on human umbilical cord. Two thousand and five hundred blood donors served as control group. For statistical analysis, we used Chi-square or Fisher's exact test. RESULTS: The frequency of IgA endomysial antibodies in our patients was significantly higher than in the control group (8...
June 20, 2017: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/28630806/prevalence-and-barriers-to-lung-cancer-screening-in-karachi-pakistan-a-cross-sectional-survey-of-smokers-and-physicians
#4
Aleeza Abbasi, Rabbia Siddiqi, Aatika Owais, Tooba Laeeq, Sara N Ali, Zonaira Mushahid, Syed M Ahsan, Aliya S Jatoi, Aleena Abbasi, Ifrah Butt, Ruba Ali, Maham Abbasi, Syeda Naintara N Jaffri, Mariam Jabir, Hajra Khanani, Kaneez Fatima
BACKGROUND: Early detection of lung cancer using low-dose computed tomography (LDCT) can potentially reduce morbidity and mortality. However, LDCT for lung cancer screening, especially in low income countries, has been underutilized. The objective of this study was to evaluate the prevalence and the potential personal, social, and economic barriers of lung cancer screening using LDCT. METHODS: A total sample of 156 smokers and 200 general physicians was collected during December 2016-February 2017 from community settings in Karachi, Pakistan...
May 15, 2017: Curēus
https://www.readbyqxmd.com/read/28629475/can-formalizing-links-among-community-health-workers-accredited-drug-dispensing-outlet-dispensers-and-health-facility-staff-increase-their-collaboration-to-improve-prompt-access-to-maternal-and-child-care-a-qualitative-study-in-tanzania
#5
Angel Dillip, Suleiman Kimatta, Martha Embrey, John C Chalker, Richard Valimba, Mariam Malliwah, John Meena, Rachel Lieber, Keith Johnson
BACKGROUND: In Tanzania, progress toward achieving the 2015 Millennium Development Goals for maternal and newborn health was slow. An intervention brought together community health workers, health facility staff, and accredited drug dispensing outlet (ADDO) dispensers to improve maternal and newborn health through a mechanism of collaboration and referral. This study explored barriers, successes, and promising approaches to increasing timely access to care by linking the three levels of health care provision...
June 19, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28629273/the-association-between-maternal-race-and-adverse-outcomes-in-twin-pregnancies-with-similar-healthcare-access
#6
Marti D Soffer, Mariam Naqvi, Stephanie Melka, Aren Gottlieb, Julie Romero, Nathan S Fox
OBJECTIVE: To compare twin pregnancy outcomes between white and nonwhite women with similar access to healthcare. METHODS: Retrospective cohort study of all twin pregnancies delivered by a single maternal-fetal medicine practice from 2005-2016. All patients had private health insurance and equal access to physician care. Outcomes were compared between white and nonwhite women using logistic regression to adjust for differences at baseline. RESULTS: Of the 858 women included, 730 (85...
June 19, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28628550/visual-and-motor-recovery-after-cognitive-therapeutic-exercises-in-cortical-blindness-a-case-study
#7
Daniele De Patre, Ann Van de Winckel, Franca Panté, Carla Rizzello, Marina Zernitz, Mariam Mansour, Lara Zordan, Thomas A Zeffiro, Erin E OʼConnor, Teresa Bisson, Andrea Lupi, Carlo Perfetti
BACKGROUND AND PURPOSE: Spontaneous visual recovery is rare after cortical blindness. While visual rehabilitation may improve performance, no visual therapy has been widely adopted, as clinical outcomes are variable and rarely translate into improvements in activities of daily living (ADLs). We explored the potential value of a novel rehabilitation approach "cognitive therapeutic exercises" for cortical blindness. CASE DESCRIPTION: The subject of this case study was 48-year-old woman with cortical blindness and tetraplegia after cardiac arrest...
July 2017: Journal of Neurologic Physical Therapy: JNPT
https://www.readbyqxmd.com/read/28628348/relation-between-peak-knee-flexion-angle-and-knee-ankle-kinetics-in-single-leg-jump-landing-from-running-a-pilot-study-on-male-handball-players-to-prevent-acl-injury
#8
Mariam A Ameer, Qassim I Muaidi
OBJECTIVES: The relationship between knee kinematics and knee-ankle kinetics during the landing phase of single leg jumping has been widely studied to identify proper strategies for preventing non-contact ACL injury. However, there is a lack of study on knee-ankle kinetics at peak knee flexion angle during jumping from running. Hence, the purpose of this study is to establish the relationship between peak knee flexion angle, knee extension moment, ankle plantar flexion moment and ground reaction force in handball players in order to protect ACL from excessive stress during single leg jumping...
June 19, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/28627830/flt3-itd-mutations-in-egyptian-patients-of-acute-myeloid-leukemia-correlation-with-cytogenetic-fab-subgroups-and-prognosis
#9
Shady Adnan-Awad, Ola Gaber, Soad A Eltokhy, Dalia Mourad, Mariam Amer, Eman Z Kandeel, Ihab Eldesouky
BACKGROUND: FLT3-ITD mutations are common in AML subgroups, particularly in Acute Promyelocytic Leukemia (APL). It infers poor prognosis in AML patients; however, its prognostic value in APL is still controversial. We aimed to assess the distribution and prognostic value of FLT3-ITD mutation within AML subgroups, focusing on APL. METHODS: In NCI, Cairo University, 346 newly diagnosed AML patients were included. Morphological, immunophenotypic and cytogenetic analysis were done at presentation and fixed follow-up points with monitoring in follow up visits of patients...
May 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/28627117/the-cognitive-features-of-idiopathic-and-dyt1-dystonia
#10
REVIEW
Marjan Jahanshahi, Mariam Torkamani
Dystonia is a common movement disorder. In this paper, we review the literature on cognitive function in idiopathic and DYT1 dystonia. In idiopathic or DYT1 dystonia, cognition is largely intact with only isolated executive dysfunction. Dystonia patients also have increased temporal and spatial discrimination thresholds, considered endophenotypes of the disorder because deficits are also shown by unaffected relatives and nonmanifesting carriers of the DYT1 mutation. Anticholinergic medication in high doses can be associated with memory impairment in dystonia...
June 19, 2017: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/28624071/corrigendum-to-genetic-parameters-for-lactose-and-its-correlation-with-other-milk-production-traits-and-fitness-traits-in-pasture-based-production-systems-j-dairy-sci-100-3754-3766
#11
https://www.readbyqxmd.com/read/28623958/knockdown-of-subunit-3-of-the-cop9-signalosome-inhibits-c2c12-myoblast-differentiation-via-nf-kappab-signaling-pathway
#12
Mariam A Ba, Jeffrey Surina, Cherie A Singer, Maria L Valencik
BACKGROUND: The COP9 signalosome (CSN) is a conserved protein complex composed of 8 subunits designated CSN1-CSN8. CSN3 represents the third subunit of the CSN and maintains the integrity of the complex. CSN3 binds to the striated muscle-specific β1D integrin tail, and its subcellular localization is altered in differentiated skeletal muscle cells. However, the role of CSN3 in skeletal muscle differentiation is unknown. The main goal of this study was to identify whether CSN3 participates in myoblast differentiation and the signalling mechanisms involved using C2C12 cells as a skeletal muscle cell model...
June 17, 2017: BMC Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28620683/modeling-production-functions-and-economic-weights-in-intensive-meat-production-of-guinea-pigs
#13
Mariam Pascual, Danny Julio Cruz, Agustín Blasco
A profit function for a typical commercial farm of intensive guinea pig production was designed. The simulated farm contained 86 cages with a ratio of 7:1 females/males, with continuous mating. Kits were weaned at 15 days of age and slaughtered for meat production at 90 days of age. The absolute (EW) and relative economic weights of the main traits were calculated. The highest EW were kits produced per kindling (US$25), kits weaned per kindling (US$22), kits born alive per kindling (US$20), and the number of kindlings per female and year (US$12)...
June 15, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28617773/pregnancy-outcomes-after-maternal-zika-virus-infection-during-pregnancy-u-s-territories-january-1-2016-april-25-2017
#14
Carrie K Shapiro-Mendoza, Marion E Rice, Romeo R Galang, Anna C Fulton, Kelley VanMaldeghem, Miguel Valencia Prado, Esther Ellis, Magele Scott Anesi, Regina M Simeone, Emily E Petersen, Sascha R Ellington, Abbey M Jones, Tonya Williams, Sarah Reagan-Steiner, Janice Perez-Padilla, Carmen C Deseda, Andrew Beron, Aifili John Tufa, Asher Rosinger, Nicole M Roth, Caitlin Green, Stacey Martin, Camille Delgado Lopez, Leah deWilde, Mary Goodwin, H Pamela Pagano, Cara T Mai, Carolyn Gould, Sherif Zaki, Leishla Nieves Ferrer, Michelle S Davis, Eva Lathrop, Kara Polen, Janet D Cragan, Megan Reynolds, Kimberly B Newsome, Mariam Marcano Huertas, Julu Bhatangar, Alma Martinez Quiñones, John F Nahabedian, Laura Adams, Tyler M Sharp, W Thane Hancock, Sonja A Rasmussen, Cynthia A Moore, Denise J Jamieson, Jorge L Munoz-Jordan, Helentina Garstang, Afeke Kambui, Carolee Masao, Margaret A Honein, Dana Meaney-Delman
Pregnant women living in or traveling to areas with local mosquito-borne Zika virus transmission are at risk for Zika virus infection, which can lead to severe fetal and infant brain abnormalities and microcephaly (1). In February 2016, CDC recommended 1) routine testing for Zika virus infection of asymptomatic pregnant women living in areas with ongoing local Zika virus transmission at the first prenatal care visit, 2) retesting during the second trimester for women who initially test negative, and 3) testing of pregnant women with signs or symptoms consistent with Zika virus disease (e...
June 16, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28614683/single-nephron-glomerular-filtration-rate-in-healthy-adults
#15
Aleksandar Denic, Jerry Mathew, Lilach O Lerman, John C Lieske, Joseph J Larson, Mariam P Alexander, Emilio Poggio, Richard J Glassock, Andrew D Rule
BACKGROUND: The glomerular filtration rate (GFR) assesses the function of all nephrons, and the single-nephron GFR assesses the function of individual nephrons. How the single-nephron GFR relates to demographic and clinical characteristics and kidney-biopsy findings in humans is unknown. METHODS: We identified 1388 living kidney donors at the Mayo Clinic and the Cleveland Clinic who underwent a computed tomographic (CT) scan of the kidney with the use of contrast material and an iothalamate-based measurement of the GFR during donor evaluation and who underwent a kidney biopsy at donation...
June 15, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28606829/incidence-and-risk-factors-predisposing-plate-removal-following-orthognathic-surgery
#16
Fredrik Widar, Mariam Afshari, Lars Rasmusson, Christer Dahlin, Hossein Kashani
OBJECTIVE: The aim of this study was to investigate the incidence and reasons for titanium fixation plate removal following orthognathic surgery, identify risk factors predisposing removal, and explore if discomfort was reduced postoperatively. STUDY DESIGN: Medical records of 404 consecutive cases were retrospectively reviewed. All patients received a questionnaire for follow-up, and 323 patients answered the questionnaire, thus forming the sample group. RESULTS: Of all the responding patients, 15% had plates removed, and 92% of these patients experienced relief from discomfort after removal of the plates...
May 4, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28601812/cardiovascular-and-type-2-diabetes-morbidity-and-all-cause-mortality-among-diverse-chronic-inflammatory-disorders
#17
Alex Dregan, Phil Chowienczyk, Mariam Molokhia
OBJECTIVES: The present study aimed to assess the relationship between inflammatory disorders with cardiometabolic diseases and mortality within a community-based population. METHODS: The UK Biobank data were used to conduct two investigations: a cross-sectional study to estimate cardiometabolic risk and a prospective cohort study to estimate mortality risk. Binary regression analyses were used to model the association between coronary heart disease, stroke, type 2 diabetes, venous thromboembolism and peripheral artery disease diagnoses with seven inflammatory disorders (eg, rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), psoriasis, ankylosing spondylitis (AS), systemic vasculitis, Crohn's disease and ulcerative colitis (UC))...
June 10, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28600309/dulce-digital-an-mhealth-sms-based-intervention-improves-glycemic-control-in-hispanics-with-type-2-diabetes
#18
Addie L Fortmann, Linda C Gallo, Maria Isabel Garcia, Mariam Taleb, Johanna A Euyoque, Taylor Clark, Jessica Skidmore, Monica Ruiz, Sapna Dharkar-Surber, James Schultz, Athena Philis-Tsimikas
OBJECTIVE: Type 2 diabetes is growing in epidemic proportions and disproportionately affects lower income, diverse communities. Text messaging may provide one of the most rapid methods to overcome the "digital divide" to improve care. RESEARCH DESIGN AND METHODS: A randomized, nonblinded, parallel-groups clinical trial design allocated N = 126 low-income, Hispanic participants with poorly controlled type 2 diabetes to receive the Dulce Digital intervention or usual care (UC)...
June 9, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28592566/combined-immune-checkpoint-blockade-as-a-therapeutic-strategy-for-brca1-mutated-breast-cancer
#19
Emma Nolan, Peter Savas, Antonia N Policheni, Phillip K Darcy, François Vaillant, Christopher P Mintoff, Sathana Dushyanthen, Mariam Mansour, Jia-Min B Pang, Stephen B Fox, Charles M Perou, Jane E Visvader, Daniel H D Gray, Sherene Loi, Geoffrey J Lindeman
Immune checkpoint inhibitors have emerged as a potent new class of anticancer therapy. They have changed the treatment landscape for a range of tumors, particularly those with a high mutational load. To date, however, modest results have been observed in breast cancer, where tumors are rarely hypermutated. Because BRCA1-associated tumors frequently exhibit a triple-negative phenotype with extensive lymphocyte infiltration, we explored their mutational load, immune profile, and response to checkpoint inhibition in a Brca1-deficient tumor model...
June 7, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28592274/the-magnitude-and-correlates-of-parvovirus-b19-infection-among-pregnant-women-attending-antenatal-clinics-in-mwanza-tanzania
#20
Mariam M Mirambo, Fatma Maliki, Mtebe Majigo, Martha F Mushi, Nyambura Moremi, Jeremiah Seni, Dismas Matovelo, Stephen E Mshana
BACKGROUND: Human parvovirus B19 (B19) infection has been associated with congenital infection which may result into a number of the adverse pregnancy outcomes. The epidemiology and the magnitude of B19 infections among pregnant women have been poorly studied in developing countries. This study was done to establish preliminary information about the magnitude of B19 among pregnant women attending antenatal clinics in the city of Mwanza, Tanzania. METHODS: A cross-sectional study was conducted between December 2014 and June 2015 among 258 pregnant women attending two antenatal clinics representing rural and urban areas in the city of Mwanza...
June 7, 2017: BMC Pregnancy and Childbirth
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