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Naiem Nassiri, Lauren A Huntress, Mitchell Simon, Susan Murphy
OBJECTIVE: No standardized therapeutic algorithm or embolic agent of choice has yet been identified for management of congenital peripheral venous malformations (VMs). Treatment options and reported outcomes therefore vary widely. Herein, we present an institution-wide algorithm for management of symptomatic congenital peripheral VMs using a single embolotherapeutic modality. METHODS: During 36 months, patients with symptomatic congenital peripheral VMs underwent contrast-enhanced magnetic resonance imaging...
May 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
Joseph J López, Daniel L Lodwick, Jennifer N Cooper, Mark Hogan, Denis King, Peter C Minneci
BACKGROUND: Sclerotherapy has been described as a treatment option for nonparasitic pediatric splenic cysts; however, there are limited data on its long-term effectiveness. METHODS: We performed a retrospective review and prospective follow-up imaging study of children treated for nonparasitic splenic cysts at our institution during 2006-2015. Included patients had International Classification of Disease, Ninth Revision, Clinical Modification diagnosis code 289...
November 2017: Journal of Surgical Research
Ronald Bush, Peggy Bush
INTRODUCTION: This study was designed to determine by histological evaluation and clinical correlation the most effective sclerosant concentration of Sotradecol® (sodium tetradecyl sulfate) and Asclera® (polidocanol) for the treatment of leg telangiectasia. METHODS: Histological studies were completed on 40 patients, all of whom were female with a mean age of 53. After sclerotherapy with varying concentrations of sclerosant solutions for the treatment of 0.8 mm and 1 mm leg telangiectasia, histological specimens were examined for the following criteria: luminal changes, subintimal changes, smooth muscle wall alterations, and vessel wall integrity...
October 12, 2016: Phlebology
Soroush Farnoosh, Debra Don, Jeffery Koempel, Andre Panossian, Dean Anselmo, Philip Stanley
OBJECTIVES: Lymphatic malformations are congenital vascular anomalies that occur from abnormal development of the lymphatic channels. Studies have shown that sclerotherapy can be a reliable alternative to surgery. The purpose of this retrospective study is to evaluate the safety and efficacy of percutaneous sclerotherapy with doxycycline and 3% Sotradecol as primary treatment for pediatric head and neck LMs, and to assess outcomes based on lesion classification, location and sclerosant used...
June 2015: International Journal of Pediatric Otorhinolaryngology
Pascal Chabrot, Ahmed Fatimi, Patrizio Delli Fraine, Lemlih Ouchchane, Marie-Mélanie Dauplat, Alain Rivard, Sophie Lerouge, Gilles Soulez
PURPOSE: To investigate whether embolization with chitosan hydrogel (CH) with or without a sclerosant (sodium tetradecyl sulphate, STS) can induce chemical endothelial ablation and prevent endothelial recanalization in a rabbit model. METHODS: Chitosan radiopaque thermogels were prepared using chitosan, β-glycerophosphate, iopamidol, and different STS concentrations. Each auricular artery of 14 New Zealand White rabbits was cannulated and injected with 0.6 mL of chitosan (CH0; n = 14) on one side and either saline (n = 3), chitosan and 1% STS (CH1; n = 6), or chitosan and 3% STS (CH3; n = 6) in the contralateral side...
June 2012: Journal of Endovascular Therapy
Giustino Albanese, Kimi L Kondo
Sclerotherapy is the therapeutic use of sclerosants in the controlled destruction of undesired target tissues. Sclerosants have been used in vascular and nonvascular settings, both as primary and adjunctive therapy. Effective sclerotherapy requires a conceptual understanding of key questions about the process being treated, including the method of delivery, the presence of flow, and the required contact time to initiate sclerosis. However, beyond technique and delivery, practical and safe application of sclerotherapy requires an understanding of the uses, limitations, dosing, and side effects of sclerosants used during interventional radiology procedures...
December 2010: Seminars in Interventional Radiology
S Elias, J K Raines
OBJECTIVE: The purpose of this study was to assess the safety and efficacy of the ClariVein(®) system that employs mechanochemical ablation of the great saphenous vein (GSV). METHOD: Patients eligible for ablation of the GSV underwent micropuncture access with only local anaesthesia to insert a 4 or 5 Fr sheath. The ClariVein(®) catheter was placed through the sheath, the wire was extruded, and the distal tip of the wire positioned 2 cm from the saphenofemoral junction under ultrasound guidance...
March 2012: Phlebology
Ronald G Bush
BACKGROUND: Treatment of healing venous ulcers continues to be a challenge; currently used techniques, as adjuncts to compression therapy aid to prevent recurrence but fail to heal ulcers. METHOD: A technique of terminal interruption of the reflux source (TIRS) was used. The TIRS procedure targets the terminal source of reflux. The purpose of the procedure is to temporarily reduce the venous hypertension at the local level, thus allowing healing to occur. By ultrasound guidance, 1% Sotradecol foam is injected into a venous branch or branches in close proximity to the ulcer bed...
September 2010: Perspectives in Vascular Surgery and Endovascular Therapy
No abstract text is available yet for this article.
November 1946: Surgery, Gynecology & Obstetrics
P A Svendsen, G Wikholm, M Rodriguez, P Enoksson, L Frisén, K Strömland, S Seregard
We evaluated sclerotherapy in the treatment of orbital lymphatic malformations. Six consecutive patients with unilateral orbital cystic masses and recurrent episodes of orbital swelling were included in this retrospective study. All have been treated with percutaneous puncture and injection of Sotradecol (sodium tetredecyl sulphate) under radiographic guidance, on one or more occasions. Reduction of orbital mass volume was documented clinically and radiologically within a few weeks in all cases. There was total regression of proptosis in three instances...
September 30, 2001: Interventional Neuroradiology
Christopher G Zochowski, Christopher J Salgado, Amir A Jamali
Venous malformations are a subset of low-flow vascular malformations. These are usually present at birth and grow commensurate with the child. The treatment of low-flow vascular malformations has been studied extensively. Many interventions have been devised to benefit this patient population in regard to the pain, ulcerations, infections, cosmetic concerns, and overall bulk associated with these malformations. Treatment can begin with compression garments. Another treatment is sclerotherapy. This can be done as a stand-alone treatment or as an adjunct to surgical excision...
July 2010: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
No abstract text is available yet for this article.
June 1947: New York State Journal of Medicine
No abstract text is available yet for this article.
July 1948: Bulletin of the School of Medicine: Official Publication of the University of Maryland
Jose I Almeida, Jeffrey K Raines
BACKGROUND: In the area of endovenous chemical ablation (sclerotherapy), there has been much debate regarding sclerosant quality and efficacy. Only sodium tetradecyl sulfate (STS) has garnered Food and Drug Administration (FDA) approval in the United States. OBJECTIVE: The primary objective of this study was to compare clinical performance measures of compounded STS from 27% industrial-strength stock (compounded STS) versus FDA-approved Sotradecol (Bioniche Pharma USA, Inc...
September 2007: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
P Benin, C D'Amico
AIM: This case study was designed to evaluate foam sclerotherapy of hemorrhoidal disease using a flexible endoscope. METHODS: We treated 250 patients of grade II-IV hemorrhoids with Sotradecol foam. To obtain sclerosing foam, we used a special foam kit, which produced a stable and standardized sclerosing foam. The quantity of foam injected into the hemorrhoids was 1 to 2 cc with a total of 6 cc for each session. Variables to assess efficacy of treatment were: pain, bleeding and prolapse...
August 2007: Minerva Chirurgica
Anke H Scultetus, J Leonel Villavicencio, Tzu-Cheg Kao, David L Gillespie, Gary D Ketron, Mark D Iafrati, Emmanouil Pikoulis, Sandra Eifert
OBJECTIVE: Postsclerotherapy pigmentation occurs in nearly 30% of patients. Hemosiderin, from degradation of the venous thrombus, is the possible cause. The hypothesis that early removal of the thrombus may eliminate or decrease the incidence of pigmentation has not been proved or documented. The objective of this study was to investigate the effects of early microthrombectomy on incidence of postsclerotherapy pigmentation. MATERIAL AND METHODS: This multicenter, randomized, controlled study involved 101 patients with varicose veins (100 women, 1 man; mean age, 46 years [range, 25-68 years])...
November 2003: Journal of Vascular Surgery
No abstract text is available yet for this article.
July 1963: Oral Surgery, Oral Medicine, and Oral Pathology
No abstract text is available yet for this article.
December 1955: Angiology
Gösta Claesson, Richard Kuylenstierna
BACKGROUND/PURPOSE: Operating lymphatic malformation (LM) may lead to nerve damage with permanent cosmetic disturbance. Even sclerosants as ethanol and Sotradecol may sometimes harm more than cure. The purpose with this study was to evaluate the effect of a relatively new drug for intralesional injections, OK-432. METHODS: The diagnosis of LM was made clinically by means of ultrasound and MRT and/or CT. Thirty-two patients (28 children) with LM were consecutively enrolled in the study...
August 1, 2002: International Journal of Pediatric Otorhinolaryngology
Pål Svendsen, Gunnar Wikholm, Miriam Rodriguez-Catarino
Vascular lesions are tumours or malformations. Haemangioma is the most common tumour. It disappears at the age of seven. Malformations may be arterial, capillary, venous, arteriovenous, lymphatic or mixed. The vascular malformations do not disappear. There are several options for treating venous or lymphatic malformations. One of them is sclerosing therapy with Sotradecol by direct puncture. We have 15 years' experience of this method but present only the last 60 patients, treated between 1997 and 2001. Excellent or good results were seen in 59 patients...
March 19, 2002: Läkartidningen
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