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Polidocanol

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https://www.readbyqxmd.com/read/29614554/-effect-of-foam-sclerotherapy-for-the-treatment-of-oropharyngeal-venous-malformation
#1
C Q Niu, H Jiang, S Y Zhou, G Shen, H B Li, J Zhang
Objective: To evaluate the safety and efficacy of foam sclerotherapy with polidocanol for the treatment of venous malformation in the oropharynx. Methods: The clinical data of 21 children with venous malformation in the oropharynx treated by foam sclerotherapy were retrospectively analyzed. There were 10 males and 11 females, ranging in age from 1 month to 13 years, with a median age of 2.3 years. MRI was performed in all children, and the diagnosis was further confirmed by radiography. After general anesthesia, the oropharynx was exposed by opening device...
March 7, 2018: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29489686/a-gastrointestinal-stromal-tumor-with-acute-bleeding-management-and-nursing
#2
Xiuju Shi, Shuxia Yu, Fenyan Wang, Qi Zhao, Hongwei Xu, Bin Li
RATIONALE: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors involving the gastrointestinal tract. A small percentage of GISTs may cause acute gastrointestinal bleeding, which requires urgent surgical intervention. PATIENT CONCERNS: In this case report, we present a 62-year-old male patient with who was hospitalized due to acute bleeding. DIAGNOSES: The patient was diagnosed as GIST with low risk. INTERVENTIONS: The patient was treated endoscopically with polidocanol sclerotherapy...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29473522/an-evidence-based-review-of-off-label-uses-of-polidocanol
#3
Seyyed Reza Sadat Ebrahimi, Elgar Enamzadeh, Hossein Babaei
BACKGROUND: Polidocanol is approved for its competence in treatment of varicose veins and spider veins; however, unfortunately, many of its off-label uses are still underappreciated. OBJECTIVE: Lack of an appropriate comprehensive review for off-label uses of this medication troubles physicians about making evidence-based decisions on prescribing it for its various outstanding off-label uses. This article attempts to provide physicians with the latest information concerning successful and unsuccessful use of polidocanol as an alternative treatment for esophageal and gastric varices, tendinopathy and epicondylitis, vascular malformations, varicocele, hydrocele and spermatocele, aneurysmal bone cysts, itching, management of gastrointestinal bleeding, simple renal cysts, reducing the incidence and severity of radio-induced dermatitis, and hemorrhoids...
February 23, 2018: Current Clinical Pharmacology
https://www.readbyqxmd.com/read/29417264/polidocanol-sclerotherapy-combined-with-transarterial-embolization-using-n-butyl-cyanoacrylate-for-extracranial-arteriovenous-malformations
#4
Akira Kitagawa, Takahiro Yamamoto, Nozomu Matsunaga, Mayako Yamaji, Shuji Ikeda, Yuichiro Izumi, Makiyo Hagihara, Toyohiro Ota, Tsuneo Ishiguchi
PURPOSE: To assess the safety and effectiveness of polidocanol sclerotherapy combined with transarterial embolization using a liquid adhesive agent (n-butyl cyanoacrylate, NBCA) for treatment of extracranial arteriovenous malformations (AVMs). MATERIALS AND METHODS: Twenty-three patients with symptomatic AVMs in the head and neck (6), upper (7) and lower extremity (10) with a mean age of 42 years (range 4-74) treated with polidocanol sclerotherapy were retrospectively assessed...
February 7, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29241409/letter-re-evaluation-of-sodium-tetradecyl-sulfate-and-polidocanol-as-sclerosants-for-leg-telangiectasia-based-on-histological-evaluation-with-clinical-correlation
#5
https://www.readbyqxmd.com/read/29241408/response-to-professor-whitely-concerning-evaluation-of-sodium-tetradecyl-sulfate-and-polidocanol-as-sclerosants-for-leg-telangiectasia-based-on-histological-evaluation-with-clinical-correlation
#6
https://www.readbyqxmd.com/read/29219197/comparison-of-ultrasound-guided-percutaneous-polidocanol-injection-versus-percutaneous-ethanol-injection-for-treatment-of-benign-cystic-thyroid-nodules
#7
Xiaohua Gong, Fang Wang, Haiyan Du, Xiaojun Chen, Bimin Shi
OBJECTIVES: We compared the efficacy, safety, and cost-effectiveness of ultrasound-guided percutaneous polidocanol injection and percutaneous ethanol injection for the treatment of benign cystic and predominantly cystic thyroid nodules. METHODS: A total of 135 cystic thyroid nodules treated by percutaneous ethanol injection and 136 cystic thyroid nodules treated by percutaneous polidocanol injection were enrolled retrospectively in this study from May 2010 to March 2016...
December 8, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29203002/complete-tendon-achilles-rupture-following-injection-of-aethoxysklerol-polidocanol-for-the-treatment-of-chronic-achilles-tendinopathy
#8
Christopher Fenelon, John G Galbraith, Paul Hession, Lester G D'Souza
Achilles tendinopathy can be a chronic disabling condition affecting both athletic and sedentary patients. Multiple new treatment approaches have developed, including shock wave therapy and various types of injection. One of the novel treatment methods used is the injection of Aethoxysklerol or polidocanol, a sclerosing substance injected under ultrasound guidance targeting areas of neovascularisation. We report the case of a 78-year-old lady who suffered a complete Achilles tendon rupture following injection of Aethoxysklerol...
December 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29179571/role-of-basal-cells-in-producing-persistent-lentivirus-mediated-airway-gene-expression
#9
Nigel Farrow, Martin Donnelley, Patricia Cmielewski, Eugene Roscioli, Nathan Rout-Pitt, Chantelle McIntyre, Ivan Bertoncello, David W Parsons
Cystic fibrosis (CF) lung disease is an ideal candidate for a genetic therapy. It has been shown previously that preconditioning with lysophosphatidylcholine (LPC) prior to lentiviral (LV) vector delivery results in long-term in vivo gene expression in the airway epithelium of CF mice. It was hypothesized that this outcome is largely due to transduction of airway basal cells that in turn pass the transgene onto their progeny. The aim of these studies was to confirm if the in vivo delivery of a human immunodeficiency virus type 1 (HIV-1) vesicular stomatitis virus envelope glycoprotein (VSV-G) pseudotyped LV vector following LPC airway conditioning results in transduction of mouse airway basal cells in situ and if the transgene is passed onto their progeny...
January 3, 2018: Human Gene Therapy
https://www.readbyqxmd.com/read/29177197/foam-sclerotherapy-during-shunt-surgery-for-portal-hypertension-and-varices
#10
Zhe Zhang, Xueming Chen, Chenyu Li, Hai Feng, Hongzhi Yu, Renming Zhu, Tianyou Wang
Objective: This preliminary study investigated the clinical safety and efficacy of foam sclerotherapy during shunt surgery to treat portal hypertension and gastroesophageal varices. Methods: Seven patients with confirmed portal hypertension and a variceal bleeding history underwent mesocaval shunt with simultaneous polidocanol foam injection into the varices. Computed tomography and endoscopic reviews were conducted within two weeks following the procedures and around six months later...
2017: Open Medicine (Warsaw, Poland)
https://www.readbyqxmd.com/read/29153963/shear-wave-elastography-swe-for-monitoring-of-treatment-of-tendinopathies-a-double-blinded-longitudinal-clinical-study
#11
Timm Dirrichs, Valentin Quack, Matthias Gatz, Markus Tingart, Björn Rath, Marcel Betsch, Christiane K Kuhl, Simone Schrading
RATIONALE AND OBJECTIVES: We aimed to investigate the diagnostic accuracy with which shear wave elastography (SWE) can be used to monitor response to treatment of tendinopathies, and to compare it to conventional ultrasound (US)-imaging methods (B-mode US (B-US) and power Doppler US (PD-US)). MATERIALS AND METHODS: A prospective Institutional Review Board-approved longitudinal study on 35 patients with 47 symptomatic tendons (17 Achilles-, 15 patellar-, and 15 humeral-epicondylar) who underwent standardized multimodal US and standardized clinical assessment before and after 6 months of treatment (tailored stretching exercise, sport break, and local Polidocanol) was carried out...
March 2018: Academic Radiology
https://www.readbyqxmd.com/read/29124942/quality-of-life-after-endovascular-sclerotherapy-of-low-flow-venous-malformations-the-efficacy-of-polidocanol-compared-with-ethanol
#12
Annamaria Weitz-Tuoretmaa, Leo Keski-Nisula, Riitta Rautio, Jussi Laranne
Background Limited information is available on mid-term results and quality of life (QOL) after endovascular sclerotherapy of venous malformations. Purpose To compare two agents-polidocanol and ethanol-with a focus on the influence on QOL after sclerotherapy. Material and Methods Forty-one consecutive patients with a venous malformation in the head and neck area or in the extremities were treated with polidocanol between 2008 and 2013. Pre- and post-treatment magnetic resonance imaging (MRI) scans were compared...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/29082587/effectiveness-and-safety-of-polidocanol-for-the-treatment-of-hemangiomas-and-vascular-malformations-a-meta-analysis
#13
REVIEW
Zhi Gao, Yi Zhang, Wei Li, Chen Shi
A meta-analysis was conducted to investigate the efficacy and safety of polidocanol versus other conventional therapies in treating hemangiomas (HMs) and vascular malformations (VMs). Literature search was conducted in the Cochrane, Embase, PubMed, Web of Science, CNKI, CBM, VIP, and WanFang databases until March 5, 2017. A meta-analysis was conducted using Revman 5.3 software. A total of 19 randomized controlled trials (RCTs) involving 1,514 participants met the inclusion criteria. Regarding the effectiveness, statistically significant differences were observed between polidocanol and all the independent treatments (p = ...
January 2018: Dermatologic Therapy
https://www.readbyqxmd.com/read/29080330/ultrasound-guided-polidocanol-foam-sclerotherapy-for-treating-venous-malformations
#14
Subhash Kumar, Kranti Bhavana, Sanjeev Kumar, Prem Kumar
AIM: To evaluate clinical and imaging outcomes after ultrasound (US)-guided 3% polidocanol (POL) foam-sclerotherapy of venous malformations (VMs). METHODS: We retrospectively evaluated consecutive VM cases over 1.5 years, with 6-month follow-up. US findings were used to classify VMs into four types depending upon extent of anechoic channels, connections to adjacent veins, and dysmorphism. Single or multiple needles were inserted depending upon lesion size, and used to inject up to 8 mL POL per session, every 2 to 4 weeks...
January 2018: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/29067510/ct-guided-percutaneous-sclerotherapy-for-low-flow-retrobulbar-intraconal-venous-malformations
#15
Biao Yang, Jian Zhao, Ling Gao, Chun-Lin Li, Xing-Rong Liu, He Jiao, Zheng-Yin Liao, Cheng Yi
BACKGROUND AND AIMS: Until now, no study has focused exclusively on low-flow retrobulbar intraconal venous malformations (RIVMs) which may require treatment due to cosmetic defect, pain, and visual dysfunction. The treatment for RIVMs which surround the optic nerve remains challenging. This case series aimed to evaluate the technical feasibility, effectiveness, and safety of percutaneous sclerotherapy with polidocanol for low-flow RIVMs, using local anesthesia. METHOD: This is a prospective, non-comparative, single-center, interventional case series...
October 24, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28980027/-insertional-achilles-tendinopathy-differentiated-diagnostics-and-therapy
#16
REVIEW
S F Baumbach, M Braunstein, M G Mack, F Maßen, W Böcker, S Polzer, H Polzer
Achilles tendinopathy at the calcaneal insertion is classified into insertional tendinopathy, retrocalcaneal and superficial bursitis. The aim of this study was to present the current evidence on conservative and surgical treatment of insertional tendinopathy of the Achilles tendon. Conservative first-line therapy includes reduction of activity levels, administration of non-steroidal anti-inflammatory drugs (NSAID), adaptation of footwear, heel wedges and orthoses or immobilization. In addition, further conservative therapy options are also available...
December 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/28973414/sclerotherapy-for-reticular-veins-in-the-lower-limbs-a-triple-blind-randomized-clinical-trial
#17
Matheus Bertanha, Rodrigo Gibin Jaldin, Regina Moura, Rafael Elias Farres Pimenta, Jamil Victor de Oliveira Mariúba, Carlos Eduardo Pinheiro Lúcio Filho, Giovana Piteri Alcantara, Carlos Roberto Padovani, Winston Bonetti Yoshida, Marcone Lima Sobreira
Importance: Reticular veins are subdermal veins located in the lower limbs and are mainly associated with aesthetic complaints. Although sclerotherapy is the treatment of choice for reticular veins in the lower limbs, no consensus has been reached regarding to the optimal sclerosant. Objective: To compare the efficacy and safety of 2 sclerosants used to treat reticular veins: 0.2% polidocanol diluted in 70% hypertonic glucose (HG) (group 1) vs 75% HG alone (group 2)...
September 27, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28890747/sclerotherapy-for-the-management-of-seromas-a-systematic-review
#18
Aditya Sood, Vasanth S Kotamarti, Paul J Therattil, Edward S Lee
Objective: Despite improved recognition of risk factors, plastic surgeons commonly encounter seromas postoperatively and must decide upon management. Current recommendations for minimally invasive, chemical management originate from the literature on management of pneumothorax and pleural effusions. A handful of published reports have suggested the efficacy of sclerotherapy in seroma management. The aim of this study was to assess the literature on the use of sclerosants to treat subcutaneous fluid collections...
2017: Eplasty
https://www.readbyqxmd.com/read/28868491/polidocanol-injection-for-the-treatment-of-rectal-ulcer-with-large-vessel-after-hemorrhoidal-band-ligation
#19
João Santos-Antunes, Armando Peixoto, Fernando Azevedo, Margarida Marques, Andreia Albuquerque, Guilherme Macedo
No abstract text is available yet for this article.
November 2016: GE Portuguese Journal of Gastroenterology
https://www.readbyqxmd.com/read/28856388/no-beneficial-effect-of-polidocanol-treatment-in-achilles-tendinopathy-a-randomised-controlled-trial
#20
B H Ebbesen, C M Mølgaard, J L Olesen, H E Gregersen, O Simonsen
PURPOSE: Polidocanol injections have been used to treat chronic Achilles tendinopathy in clinical settings, but the few studies published show inconsistent results. The aim of this study was to evaluate the mid-term effect of Polidocanol in patients with chronic Achilles tendinopathy. It was hypothesised that patients treated with Polidocanol would have significant improvements in the outcome measures investigated compared to patients treated with a placebo treatment at mid-term follow-up...
August 30, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
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