keyword
MENU ▼
Read by QxMD icon Read
search

hur

keyword
https://www.readbyqxmd.com/read/28231690/downregulation-of-hur-inhibits-the-progression-of-esophageal-cancer-through-interleukin-18
#1
Xiaohui Xu, Cheng Song, Zhihua Chen, Chenxiao Yu, Yi Wang, Yiting Tang, Judong Luo
Purpose: To investigate the effect of HuR downregulation and the potential target genes of HuR on the progression of esophageal squamous cell carcinoma (ESCC). Materials and Methods: In this study, a proteomics assay was used to detect the expression of proteins after HuR downregulation, and a luciferase assay was used to detect the potential presence of a HuR binding site on the 3'-UTR of IL-18. In addition, colony formation assay, MTT, EdU incorporation assay, Western blot, flow cytometry, immunohistochemistry, transwell invasion assay and wound healing assay were used...
February 24, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28227493/recommendations-for-antiarrhythmic-drugs-based-on-latent-semantic-analysis-with-fc-means-clustering
#2
Juyoung Park, Mingon Kang, Junbeom Hur, Kyungtae Kang, Juyoung Park, Mingon Kang, Junbeom Hur, Kyungtae Kang, Mingon Kang, Junbeom Hur, Juyoung Park, Kyungtae Kang
In this paper, we propose a novel model for the appropriate recommendation of antiarrhythmic drugs by introducing a fusion of a latent semantic analysis and k-means clustering. Our model not only captures the latent factors between the types of arrhythmia and patients but also has the ability to search a group of patients with similar arrhythmias. The performance studies conducted against the MIT-BIH arrhythmia database show that clinicians accepted 66.67% of the drugs recommended from our model with a balanced f-score of 38...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225640/absolute-delay-multiphase-reconstruction-reduces-prosthetic-valve-related-and-atrial-fibrillation-related-artifacts-at-cardiac-ct
#3
Young Joo Suh, Dong Jin Im, Yoo Jin Hong, Hye-Jeong Lee, Jin Hur, Byoung Wook Choi, Young Jin Kim
OBJECTIVE: The objective of our study was to compare the image quality of cardiac CT images of mechanical valves in patients with irregular heart rates (HRs) using absolute-delay multiphase reconstruction versus relative-delay multiphase reconstruction. MATERIALS AND METHODS: A total of 26 patients with 40 mechanical valves who had atrial fibrillation during CT were included. The image quality of the CT scans was assessed for the subvalvular and valvular regions on a 4-point scale...
February 22, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28222725/how-do-medical-students-differ-in-their-interpersonal-needs
#4
Yera Hur, A Ra Cho, Sun Huh, Sun Kim
BACKGROUND: Knowing one's interpersonal relationship preferences can be tremendously helpful for medical students' lives. The purpose of this study was to examine the interpersonal needs in medical students. METHODS: Between 2010 and 2015, a total of 877 students from four Korean medical schools took the Korean version of the Fundamental Interpersonal Relations Orientation - Behaviour (FIRO-B) scale. The FIRO-B results were analyzed by descriptive statistics, frequency, independent t-test, and one-way ANOVA...
February 21, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28220067/shared-and-task-specific-muscle-synergies-during-normal-walking-and-slipping
#5
Mohammad Moein Nazifi, Han Ul Yoon, Kurt Beschorner, Pilwon Hur
Falling accidents are costly due to their prevalence in the workplace. Slipping has been known to be the main cause of falling. Understanding the motor response used to regain balance after slipping is crucial to developing intervention strategies for effective recovery. Interestingly, studies on spinalized animals and studies on animals subjected to electrical microstimulation have provided major evidence that the Central Nervous System (CNS) uses motor primitives, such as muscle synergies, to control motor tasks...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28219770/silencing-of-the-mrna-binding-protein-hur-increases-the-sensitivity-of-colorectal-cancer-cells-to-ionizing-radiation-through-upregulation-of-caspase-2
#6
Amel Badawi, Stephanie Hehlgans, Josef Pfeilschifter, Franz Rödel, Wolfgang Eberhardt
Increased abundance of the mRNA-binding protein human antigen R (HuR) is a characteristic feature of many cancers and frequently associated with a high grade malignancy and therapy resistance. HuR elicits a broad cell survival program mainly by stabilizing or increasing the translation of mRNAs coding for anti-apoptotic effector proteins. Conversally, we previously identified the pro-apoptotic caspase-2 as a novel HuR target which is mainly regulated at the level of translation. In this study, we investigated whether siRNA-mediated HuR knockdown interferes with cell survival and radiation sensitivity by monitoring apoptosis, DNA repair and three-dimensional (3D) clonogenic survival...
February 17, 2017: Cancer Letters
https://www.readbyqxmd.com/read/28217710/shedding-light-on-the-darc-knight-as-a-guardian-of-hematopoietic-stem-cell-quiescence
#7
COMMENT
Pniel Nham, Jae-Il Choi, Jin Hur, Sung Hee Baek, Hyo-Soo Kim
No abstract text is available yet for this article.
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28217669/single-port-access-laparoscopic-surgery-for-large-adnexal-tumors-initial-51-cases-of-a-single-institute
#8
Bo Ra Cho, Jae Won Han, Tae Hyun Kim, Ae Ra Han, Sung Eun Hur, Sung Ki Lee, Chul Jung Kim
OBJECTIVE: Investigation of initial 51 cases of single port access (SPA) laparoscopic surgery for large adnexal tumors and evaluation of safety and feasibility of the surgical technique. METHODS: We retrospectively reviewed the medical records of the first 51 patients who received SPA laparoscopic surgery for large adnexal tumors greater than 10 cm, from July 2010 to February 2015. RESULTS: SPA adnexal surgeries were successfully completed in 51 patients (100%)...
January 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28214178/validation-of-the-university-of-washington-quality-of-life-chinese-version-uwqol-c-for-head-and-neck-cancer-patients-in-taiwan
#9
Yun-Hsiang Lee, Yeur-Hur Lai, Bevan Yueh, Pen-Yuan Chu, Yen-Ju Chen, Shu-Ching Chen, Cheng-Ping Wang
BACKGROUND/PURPOSE: The purposes of this three-phase study were to: (1) translate and evaluate the burden, content, and face validity of the Chinese version of the University of Washington Quality of Life Scale, version 4 (UWQOL-v4-C); and (2) examine the psychometric properties of the UWQOL-v4-C in oral cancer and laryngeal cancer patients in Taiwan. METHODS: This instrument translation and validation study was part of a major research project. The first phase of this study developed and validated the content of the UWQOL-v4-C...
February 14, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28209640/quantized-thermal-transport-in-single-atom-junctions
#10
Longji Cui, Wonho Jeong, Sunghoon Hur, Manuel Matt, Jan C Klöckner, Fabian Pauly, Peter Nielaba, Juan Carlos Cuevas, Edgar Meyhofer, Pramod Reddy
Thermal transport in individual atomic junctions and chains is of great fundamental interest due to unique quantum effects expected to arise in them. Here, by employing novel, custom-fabricated, picowatt-resolution calorimetric scanning probes, we measure the thermal conductance of gold and platinum metallic wires down to single-atom junctions. Our work reveals that the thermal conductance of gold single atom junctions is quantized at room temperature and shows that the Wiedemann-Franz law relating thermal and electrical conductance is satisfied even in single-atom contacts...
February 16, 2017: Science
https://www.readbyqxmd.com/read/28205057/comparative-effectiveness-of-adjuvant-chemoradiotherapy-after-gastrectomy-among-older-patients-with-gastric-adenocarcinoma-a-seer-medicare-study
#11
Jennifer M Yeh, Angela C Tramontano, Chin Hur, Deborah Schrag
BACKGROUND: Since the INT-0116 trial reported a survival advantage, postoperative chemoradiotherapy (CRT) has been a care standard for US patients in whom gastric adenocarcinoma has been diagnosed. We sought to estimate the association between treatment and survival among the older US Medicare population. METHODS: This is a retrospective cohort study of Medicare beneficiaries aged 65-79 years with stage IB-III gastric adenocarcinoma diagnosed between 2002 and 2009 in a Surveillance, Epidemiology, and End Results region...
February 15, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/28202896/effect-of-mild-hypercapnia-on-lung-oxygenation-in-sitting-position-during-shoulder-arthroscopy-under-general-anesthesia
#12
Hyun Jeong Kwak, Ji Yeon Lee, Jong Wha Lee, Hong Soon Kim, Ho Jin Hur, Ji Young Kim
BACKGROUND Mild hypercapnia is permitted during surgeries in sitting position under general anesthesia to maintain cerebral regional oxygen saturation (rSO2). However, since hypoventilation may cause gas exchange impairment, we evaluated effects of mild hypercapnia on lung oxygenation during shoulder arthroscopy in sitting position. MATERIAL AND METHODS Forty patients were randomly allocated to a normocapnia group (ETCO2 35 mmHg, n=20) or a hypercapnia group (45 mmHg, n=20). The mean arterial pressure (MAP), heart rate (HR), and rSO2 were measured 5 min after intubation in supine position (T0), and at 2, 4, 6, 8, 10, 20, 30, 40, 50, and 60 min of remaining in sitting position (T1-10)...
February 16, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28197330/the-relationship-between-smoking-and-unhealthy-weight-control-behaviors-among-korean-adolescents-the-tenth-korea-youth-risk-behavior-web-based-survey-2014
#13
Won Yong Sim, Young Gyu Cho, Jae Heon Kang, Hyun Ah Park, Kyoung Woo Kim, Yang Im Hur, Koh Eun Shin, Gyeong Ran Byeon
BACKGROUND: Adolescent smoking is positively related to weight control attempts, especially by unhealthy methods. The co-occurrence of smoking and unhealthy weight control behaviors may cause serious health problems in adolescents. This study examined the relationship of smoking with unhealthy weight control behaviors among Korean adolescents. METHODS: This cross-sectional study involved 31,090 students of grades 7 to 12, who had tried to reduce or maintain their weight during the 30 days prior to The Tenth Korea Youth Risk Behavior Web-based Survey, 2014...
January 2017: Korean Journal of Family Medicine
https://www.readbyqxmd.com/read/28196122/detrimental-elavl-1-hur-dependent-gsk3%C3%AE-mrna-stabilization-impairs-resolution-in-acute-respiratory-distress-syndrome
#14
Olivia Hoffman, Nana Burns, István Vadász, Holger K Eltzschig, Michael G Edwards, Christine U Vohwinkel
A hallmark of acute respiratory distress syndrome (ARDS) is accumulation of protein-rich edema in the distal airspaces and its removal is critical for patient survival. Previous studies have shown a detrimental role of Glycogen Synthase Kinase (GSK) 3β during ARDS via inhibition of alveolar epithelial protein transport. We hypothesized that post-transcriptional regulation of GSK3β could play a functional role in ARDS resolution. To address this hypothesis, we performed an in silico analysis to identify regulatory genes whose expression correlation to GSK3β messenger RNA utilizing two lung cancer cell line array datasets...
2017: PloS One
https://www.readbyqxmd.com/read/28195541/assessment-of-egfr-mutation-status-using-cell-free-dna-from-bronchoalveolar-lavage-fluid
#15
Sojung Park, Jae Young Hur, Kye Young Lee, Jae Cheol Lee, Jin Kyung Rho, Sun Hwa Shin, Chang-Min Choi
BACKGROUND: Much attention has been focused on epidermal growth factor receptor (EGFR) mutation testing since the introduction of EGFR-tyrosine kinase inhibitors have improved survival in EGFR-positive lung cancer patients. Liquid biopsy using circulating tumor cells or cell-free DNA (cfDNA) has enabled less invasive testing, but requires a highly sensitive method. To date, liquid biopsy using bronchoalveolar lavage (BAL) fluid has rarely been used. METHODS: From 20 patients with lung adenocarcinoma, we isolated cfDNA from 20 samples of cell-free BAL fluid and 19 cell-free bronchial washing samples...
February 14, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28193415/changes-of-sodium-nitrate-nitrite-and-n-nitrosodiethylamine-during-in-vitro-human-digestion
#16
Hyeong Sang Kim, Sun Jin Hur
This study aimed to determine the changes in sodium nitrate, sodium nitrite, and N-nitrosodiethylamine (NDEA) during in vitro human digestion, and the effect of enterobacteria on the changes in these compounds. The concentrations of nitrate, nitrite, and NDEA were significantly reduced from 150, 150, and 1ppm to 42.8, 63.2, and 0.85ppm, respectively, during in vitro human digestion (p<0.05). The enterobacteria Escherichia coli and Lactobacillus casei reduced the amount of these compounds present during in vitro human digestion...
June 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28188454/serum-25-hydroxyvitamin-d-cutoffs-for-functional-bone-measures-in-postmenopausal-osteoporosis
#17
D Y Lee, J H Jee, Y Y Cho, J Y Jang, T Y Yu, T H Kim, Y J Hong, W-J Hong, S-M Jin, K Y Hur, J H Kim, S W Kim, J H Chung, M K Lee, Y-K Min
: This study sought to determine the minimal serum 25-hydroxyvitamin D [25(OH)D] concentration required to maintain bone health in postmenopausal women with low bone mass. A serum 25(OH)D concentration of 20 ng/mL rather than 30 ng/mL was appropriate for bone health. INTRODUCTION: There is no consensus on the minimal serum 25-hydroxyvitamin D [25(OH)D] concentration required to maintain bone health. The aim of this study was to investigate the relationship between 25(OH)D measured via liquid chromatography-mass spectrometry (LC-MS/MS), which is the current gold standard, and biochemical markers of bone turnover, PTH, and bone mineral densitometry (BMD)...
February 10, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28183975/double-heterojunction-nanorod-light-responsive-leds-for-display-applications
#18
Nuri Oh, Bong Hoon Kim, Seong-Yong Cho, Sooji Nam, Steven P Rogers, Yiran Jiang, Joseph C Flanagan, You Zhai, Jae-Hwan Kim, Jungyup Lee, Yongjoon Yu, Youn Kyoung Cho, Gyum Hur, Jieqian Zhang, Peter Trefonas, John A Rogers, Moonsub Shim
Dual-functioning displays, which can simultaneously transmit and receive information and energy through visible light, would enable enhanced user interfaces and device-to-device interactivity. We demonstrate that double heterojunctions designed into colloidal semiconductor nanorods allow both efficient photocurrent generation through a photovoltaic response and electroluminescence within a single device. These dual-functioning, all-solution-processed double-heterojunction nanorod light-responsive light-emitting diodes open feasible routes to a variety of advanced applications, from touchless interactive screens to energy harvesting and scavenging displays and massively parallel display-to-display data communication...
February 10, 2017: Science
https://www.readbyqxmd.com/read/28182215/risk-factors-for-transmission-of-middle-east-respiratory-syndrome-coronavirus-infection-during-the-2015-outbreak-in-south-korea
#19
Seung Woo Kim, Jung Wan Park, Hee-Dong Jung, Jeong-Sun Yang, Yong-Shik Park, Changhwan Lee, Kyung Min Kim, Keon-Joo Lee, Donghyok Kwon, Young Joo Hur, BoYoul Choi, Moran Ki
No abstract text is available yet for this article.
February 9, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28181567/the-mitotic-checkpoint-regulator-rae1-induces-aggressive-breast-cancer-cell-phenotypes-by-mediating-epithelial-mesenchymal-transition
#20
Ji Hoon Oh, Ho Hur, Ji-Yeon Lee, Yeejeong Kim, Younsoo Seo, Myoung Hee Kim
The gene RAE1 encodes ribonucleic acid export 1 (RAE1), which is involved in mRNA export and is known to serve as a mitotic checkpoint regulator. In addition, RAE1 haplo-insufficiency leads to chromosome missegregation and early aging-associated phenotypes. In humans, a positive correlation has been found between RAE1 copy number abnormalities and gene amplification in breast cancer cells. However, the precise functional role of RAE1 in breast cancer remains to be determined. An in silico analysis of data retrieved from GENT and cBio-Portal identified RAE1 upregulation in breast cancer tissues relative to normal breast cells...
February 9, 2017: Scientific Reports
keyword
keyword
115547
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"