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anesthesia and cancer

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https://www.readbyqxmd.com/read/29243798/effects-of-propofol-or-sevoflurane-anesthesia-on-the-perioperative-inflammatory-response-pulmonary-function-and-cognitive-function-in-patients-receiving-lung-cancer-resection
#1
H-T Tian, X-H Duan, Y-F Yang, Y Wang, Q-L Bai, X Zhang
OBJECTIVE: To investigate the effects of propofol and sevoflurane anesthesia on the inflammatory response, pulmonary function and cognitive function of patients undergoing lung cancer resection and their differences. PATIENTS AND METHODS: 62 patients with lung cancer who underwent pulmonary lobectomy from January 2014 to January 2016 in Jining First People's Hospital were selected and randomly divided into two groups: the propofol group (n=31) and the sevoflurane group (n=31)...
December 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29243490/percutaneous-cryoablation-of-breast-tumors-in-patients-with-stable-metastatic-breast-cancer-safety-feasibility-and-efficacy
#2
Beji H, Pilleul F, Picard R, Tredan O, Bouhamama A, Peix M, Mavrovi E, Mastier C
PURPOSE: To evaluate safety, feasibility, and efficacy of percutaneous cryoablation of breast tumors in patients with clinically stable metastatic breast cancer, and to compare the findings with reports on alternative procedures, namely surgery and local radiotherapy. METHODS: Seventeen female patients (average age of 54.8 years +/- 10.8 ; range 37-72) with primary breast tumor not surgically treated because of metastatic disease were included. Patients were treated for their primary lesion by percutaneous cryotherapy in period of stable disease...
December 15, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29241077/pectoral-nerve-blocks-to-improve-analgesia-after-breast-cancer-surgery-a-prospective-randomized-and-controlled-trial
#3
Neethu M, Ravinder Kumar Pandey, Ankur Sharma, Vanlalnghaka Darlong, Jyotsna Punj, Renu Sinha, Preet Mohinder Singh, Nandini Hamshi, Rakesh Garg, Chandralekha Chandralekha, Anurag Srivastava
STUDY OBJECTIVE: To evaluate the analgesic efficacy of ultrasound guided combined pectoral nerve blocks I and II in patients scheduled for surgery for breast cancer. DESIGN: Prospective, randomized, control trial. SETTING: Operating rooms in a tertiary care hospital of Northern India. PATIENTS: Sixty American Society of Anesthesiologists status I to II adult women, aged 18-70years were enrolled in this study. INTERVENTIONS: Patients were randomized into two groups (30 patients in each group), PECS (P) group and control (C) group...
December 11, 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/29239457/opioids-and-immunosupression-in-oncological-postoperative-patients
#4
José Luis Bonilla-García, Manuel Cortiñas-Sáenz, Esperanza Del Pozo-Gavilán
INTRODUCTION: Recent animal studies demonstrated immunosuppressive effects of opioid withdrawal resulting in a higher risk of infection. The aim of this study was to determine the impact of remifentanil discontinuation on Post-Anesthesia Care Unit (PACU)-acquired infection after a schedule of sedoanalgesia of at least 6 days. METHOD: All patients over 18 years of age with a unit admission of more than 4 days were consecutively selected. The study population was the one affected by surgical pathology of any origin where sedation was based on any hypnotic and the opioid remifentanil was used as analgesic for at least 96 hours in continuous perfusion...
September 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/29232269/mr-guided-biopsy-and-focal-therapy-new-options-for-prostate-cancer-management
#5
Fuad F Elkhoury, Demetrios N Simopoulos, Leonard S Marks
PURPOSE OF REVIEW: Options for prostate cancer management are rapidly expanding. The recent advent of MRI technology has led to guided prostate biopsies by radiologists working in-bore or by urologists using MR/US fusion technology. The resulting tumor visualization now provides the option of focal therapy. Currently available are highly directed energies - focused ultrasound (HIFU), cryotherapy, and laser - all offering the hope of curing prostate cancer with few side effects. RECENT FINDINGS: MRI now enables visualization of many prostate cancers...
December 11, 2017: Current Opinion in Urology
https://www.readbyqxmd.com/read/29231608/-influence-of-electroacupuncture-pretreatment-on-intestinal-function-in-the-patients-of-colorectal-cancer-surgery
#6
Sicong Mai, Jinhai Meng, Wenjuan Wang, Shuhui Lang
OBJECTIVE: To observe the effects of electroacupuncture (EA) pretreatment on the intestinal function, inflammatory reaction and blood lactic acid in the patients of colorectal cancer surgery. METHODS: Sixty patients of colorectal cancer laparotomy at selective period, aged from 18 to 59 years old were selected. According toⅠ-Ⅲ grade of American Society of Anesthesiologists (ASA), the patients were randomized into group A (total intravenous anesthesia), group B[total intravenous anesthesia combined with EA pretreatment at Zusanli (ST 36), Shangjuxu (ST 37) and Xiajuxu (ST 39) on the right side] and group C[total intravenous anesthesia combined with EA pretreatment at Zhongwan (CV 12), Tianshu (ST 25), Zusanli (ST 36), Shangjuxu (ST 37) and Xiajuxu (ST 39) on the right side], 20 cases in each one...
May 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29231542/-clinical-research-of-electroacupuncture-on-the-analgesic-effect-of-thoracic-perioperative-stage
#7
Mintao Zhou, Yu Li, Xuechang Han, Qunzhi Xing, Yiyao Wang, Xu Dong, Junxiao Chang
OBJECTIVE: To discuss the clinical therapeutic effects of electroacupuncture at Neimadian (Extra) and Neiguan (PC 6) on the analgesic effect of thoracic perioperative stage and its effect mechanism. METHODS: Sixty cases of esophageal cancer with elective radical resection under general anesthesia were divided into an observation group and a control group according to the operation sequence, 30 cases in each one. In the control group, the general anesthesia was simply applied and sufentanil was administered for patient controlled intravenous analgesia (PCIA) after operation...
July 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29230120/the-relationship-between-regional-anesthesia-and-cancer-a-metaanalysis
#8
REVIEW
Ravi K Grandhi, Samuel Lee, Alaa Abd-Elsayed
Background: Some studies have suggested using epidural analgesia after cancer surgery to reduce metastasis. This article examines the relationship between regional anesthesia (RA) and cancer metastasis in an array of cancers. Methods: We conducted a review of the literature using PubMed and included 67,577 patients across 28 studies in a metaanalysis, evaluating the hazard ratios (HRs) of overall survival, recurrence-free survival, and biochemical recurrence-free survival...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/29221291/airway-stenting-in-patients-requiring-intubation-due-to-malignant-airway-stenosis-a-10-year-experience
#9
Masahide Oki, Hideo Saka, Kazumi Hori
Background: Critically ill patients with severe acute respiratory failure due to malignant airway stenosis often require emergency intubation and mechanical ventilation. Urgent intervention is necessary for the survival of such patients. The aim of this study was to determine the efficacy and outcomes of airway stenting in patients with malignant airway stenosis requiring emergency intubation. Methods: Patients with malignant airway stenosis who underwent emergency intubation prior to airway stent placement from September 2005 to September 2015 in a single center were retrospectively reviewed...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29211841/perioperative-benefit-and-outcome-of-thoracic-epidural-in-esophageal-surgery-a-clinical-review
#10
P Feltracco, A Bortolato, S Barbieri, E Michieletto, E Serra, A Ruol, S Merigliano, C Ori
Surgery for esophageal cancer is a highly stressful and painful procedure, and a significant amount of analgesics may be required to eliminate perioperative pain and blunt the stress response to surgery. Proper management of postoperative pain has invariably been shown to reduce the incidence of postoperative complications and accelerate recovery. Neuraxial analgesic techniques after major thoracic and upper abdominal surgery have long been established to reduce respiratory, cardiovascular, metabolic, inflammatory, and neurohormonal complications...
December 2, 2017: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29203988/correlation-of-transabdominal-ultrasonography-and-cystoscopy-in-follow-up-of-patients-with-non-muscle-invasive-bladder-cancer
#11
Ahluwalia Puneet, Nair Balagopal, Kumar Ginil, Mathew Georgie, K V Sanjeevan, Thomas Appu
Cystoscopy (CS) is considered to be the gold standard in the follow-up of non-muscle invasive bladder cancer. However, CS is invasive, time-consuming, and expensive. On the other hand, modern sensitive transducers have improved the imaging of urinary tract rendering transabdominal ultrasonography (US) more effective in visualizing intraluminal filling defects in the bladder than it was in the past. Twenty-five follow-up patients of low-risk bladder cancer meeting the inclusion and exclusion criteria were included in study...
December 2017: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29203759/-right-hemicolectomy-under-spinal-anesthesia-due-to-cancer-of-ascending-large-bowel-case-report
#12
Gniewomir Ćwiertnia, Michał Dyaczyński
Surgery procedures of the abdomen cavity are commonly performed in general anaesthesia. Patients from high risk group with circulatory insufficiency, respiratory failure pose a problem. They undergo surgical procedures for life indications and emergency cases. Regional anaesthesia can be an alternative for general anaesthesia, and makes planned surgical treatment possible for this group of patients. The study presents the case of 79-year-old male with chronic obstructive pulmonary disease, after left lung upper lobectomy, arterial hypertension, who underwent operation due to ascending large bowel cancer under spinal anaesthesia as planned...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29202701/effects-of-sevoflurane-and-propofol-on-the-development-of-pneumonia-after-esophagectomy-a-retrospective-cohort-study
#13
Guo-Hua Zhang, Wen Wang
BACKGROUND: Postoperative pneumonia (PP) is one of the common complications following esophagectomy and associated with poor short- and long-term outcomes. Sevoflurane and propofol, which have inflammatory-modulating effects, are common used general anesthetics. This study aimed to compare the effects of anesthesia with sevoflurane and propofol on the development of PP after esophageal surgery for cancer. METHODS: The electronic medical records of patients who underwent elective esophagectomy between July 2013 and July 2016 were reviewed...
December 4, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/29189539/effect-of-continuous-systemic-administration-of-esmolol-on-intraocular-pressure-during-surgery-in-a-sustained-steep-trendelenburg-position
#14
Jin Joo, Jiyoung Kim, Jaemin Lee
PURPOSE: To investigate the effects of continuous systemic administration of esmolol on intraocular pressure (IOP) during laparoscopic and robotic surgeries for recto-sigmoid cancer in a steep Trendelenburg position. MATERIALS AND METHODS: A total of 50 patients undergoing laparoscopic surgery in a steep Trendelenburg position were included. Patients in the esmolol (E) group received a 0.25 mg/kg IV loading dose of esmolol before anesthesia, followed by an infusion of 15 μg/kg/min throughout the operation...
December 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29185400/safety-of-trans-nasal-percutaneous-endoscopic-gastrostomy-placement
#15
Lubna Kamani, Kailash Raj Makhejani, Baseer Sultan Ahmad
OBJECTIVE: To evaluate the safety of trans-nasal percutaneous endoscopic gastrostomy (TPEG) placement for nutrition in patients where oral approach is not possible. STUDY DESIGN: Case-series. PLACE AND DURATION OF STUDY: April 2010 to April 2016 in the Department of Gastroenterology at Liaquat National Hospital, Karachi. METHODOLOGY: Patients underwent trans-nasal PEG placement and were included in this study. Inclusion criteria were either gender of any age and patients referred for PEG tube placement in whom oral PEG tube insertion was not possible...
December 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29176592/a-permanent-window-for-the-murine-lung-enables-high-resolution-imaging-of-cancer-metastasis
#16
David Entenberg, Sonia Voiculescu, Peng Guo, Lucia Borriello, Yarong Wang, George S Karagiannis, Joan Jones, Francis Baccay, Maja Oktay, John Condeelis
Stable, high-resolution intravital imaging of the lung has become possible through the utilization of vacuum-stabilized imaging windows. However, this technique is extremely invasive and limited to only hours in duration. Here we describe a minimally invasive, permanently implantable window for high-resolution intravital imaging of the murine lung that allows the mouse to survive surgery, recover from anesthesia, and breathe independently. Compared to vacuum-stabilized windows, this window produces the same high-quality images without vacuum-induced artifacts; it is also less invasive, which allows imaging of the same lung tissue over a period of weeks...
November 27, 2017: Nature Methods
https://www.readbyqxmd.com/read/29163846/does-the-type-of-anesthesia-really-affect-the-recurrence-free-survival-after-breast-cancer-surgery
#17
Myoung Hwa Kim, Dong Wook Kim, Joo Heung Kim, Ki Young Lee, Seho Park, Young Chul Yoo
Background: Although previous studies have suggested that propofol inhibits cancer recurrence and metastasis, the association between anesthetic agents and the recurrence of breast cancer has not been clearly investigated. We compared total intravenous anesthesia and balanced anesthesia with volatile agents to investigate the differences in their effects on recurrence-free survival and overall survival after breast cancer surgery. Materials and Methods: The electronic medical records of 2,729 patients who underwent breast cancer surgery between November 2005 and December 2010 were retrospectively reviewed to analyze the factors associated with recurrence-free survival after surgery...
October 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/29161749/role-of-drug-anesthesia-and-cancer
#18
Mahmoud Reza Moradkhani, Arash Karimi
Mortality and morbidity rate among cancer patients is at an alarming rate and its ratio of incidence is increasing as a result of its effects of metastasis and recurrence in its patients. Anesthetists are faced with the challenges daily of handling and treating cancer patients, for surgical resection to removal of the primary tumor. Retrospective analyses and studies have proposed a link between anesthetic technique and cancer outcomes. In this mini-review, we will give a summary of some of the available effects of anesthetic and analgesic techniques on cancer metastasis as derived from experimental cell culture and live animal data and also from clinical studies...
November 21, 2017: Drug Research
https://www.readbyqxmd.com/read/29158975/assessment-of-perioperative-stress-in-colorectal-cancer-by-use-of-in-vitro-cell-models-a-systematic-review
#19
Tove Kirkegaard, Mikail Gögenur, Ismail Gögenur
Background: The perioperative period is important for patient outcome. Colorectal cancer surgery can lead to metastatic disease due to release of disseminated tumor cells and the induction of surgical stress response. To explore the overall effects on surgically-induced changes in serum composition, in vitro model systems are useful. Methods: A systematic search in PubMed and EMBASE was performed to identify studies describing in vitro models used to investigate cancer cell growth/proliferation, cell migration, cell invasion and cell death of serum taken pre- and postoperatively from patients undergoing colorectal tumor resection...
2017: PeerJ
https://www.readbyqxmd.com/read/29158935/synchronous-hpv-related-cancer-of-bilateral-tonsils-detected-using-transoral-endoscopic-examination-with-narrow-band-imaging
#20
Fukuko Shimizu, Kenji Okami, Koji Ebisumoto, Daisuke Maki, Akihiro Sakai, Go Ogura, Naoya Nakamura, Masahiro Iida
Background: The incidence of human papillomavirus- (HPV-) related oropharyngeal squamous cell carcinoma (OPSCC) has been rapidly increasing worldwide. HPV is reported in approximately 50% cases of OPSCC in Japan. However, there are few reports of synchronous bilateral HPV-positive tonsillar carcinoma, and, in almost all those cases, carcinoma was detected using positron emission tomography/computed tomography and/or bilateral tonsillectomy. Methods and Results: We report the case of a 63-year-old male with bilateral tonsillar carcinoma detected using transoral endoscopic examination with narrow-band imaging (NBI)...
2017: Case Reports in Otolaryngology
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