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https://www.readbyqxmd.com/read/29672368/pectoral-i-block-does-not-improve-postoperative-analgesia-after-breast-cancer-surgery-a-randomized-double-blind-dual-centered-controlled-trial
#1
Jérôme Cros, Patrick Sengès, Suzan Kaprelian, Julie Desroches, Caroline Gagnon, Anaïs Labrunie, Benoît Marin, Sabrina Crépin, Nathalie Nathan, Pierre Beaulieu
BACKGROUND AND OBJECTIVES: General anesthesia for breast surgery may be supplemented by using a regional anesthetic technique. We evaluated the efficacy of the first pectoral nerve block (Pecs I) in treating postoperative pain after breast cancer surgery. METHODS: A randomized, double-blind, dual-centered, placebo-controlled trial was performed. One hundred twenty-eight patients scheduled for unilateral breast cancer surgery were recruited. A multimodal analgesic regimen and surgeon-administered local anesthetic infiltration were used for all patients...
April 18, 2018: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29670012/percutaneous-imaging-guided-biopsy-of-bone-metastases
#2
REVIEW
Dimitrios Filippiadis, Argyro Mazioti, Alexios Kelekis
Approximately 70% of cancer patients will eventually develop bone metastases. Spine, due to the abundance of red marrow in the vertebral bodies and the communication of deep thoracic-pelvic veins with valve-less vertebral venous plexuses, is the most common site of osseous metastatic disease. Open biopsies run the risk of destabilizing an already diseased spinal or peripheral skeleton segment. Percutaneous biopsies obviate such issues and provide immediate confirmation of correct needle location in the area of interest...
April 18, 2018: Diagnostics
https://www.readbyqxmd.com/read/29660253/airway-stenting-for-patients-with-airway-stenosis-due-to-small-cell-lung-cancer
#3
Masahide Oki, Hideo Saka
BACKGROUND: Airway stenting has been reported to be useful for patients with malignant airway stenosis as a bridge to tumor-specific therapy, such as chemotherapy and radiation therapy, as well as palliative therapy. However, its role in patients with small-cell lung cancer (SCLC), the most aggressive lung cancer subtype, is unclear. We investigated the efficacy of airway stenting for patients with airway stenosis resulting from SCLC. METHODS: All stenting procedures were performed using both rigid and flexible bronchoscopes under general anesthesia...
April 16, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29656688/sensory-preservation-in-neck-dissection-outcomes-of-a-sub-sternocleidomastoid-approach
#4
Keigo Honda, Ryo Asato, Jun Tsuji, Masakazu Miyazaki, Shinpei Kada, Yukiko Kataoka, Akiko Taura, Mami Morita
OBJECTIVE: Cutaneous anesthesia in early postoperative period is common after neck dissection even if the cervical nerve (CN) rootlets are preserved. The aim of this study was to evaluate if the preservation of the terminal branches of CNs using sub-sternocleidomastoid (SCM) approach combined with medially placed skin incision can prevent early postoperative anesthesia. MATERIAL AND METHODS: A retrospective chart review was performed on 129 neck dissections in 87 head and neck cancer patients...
April 14, 2018: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29643620/opioid-free-anesthesia-for-breast-cancer-surgery-an-observational-study
#5
Swagata Tripathy, Satyajit Rath, Suresh Agrawal, P Bhaskar Rao, A Panda, T S Mishra, Sukdev Nayak
Background and Aims: Opioids are associated with postoperative nausea, vomiting, drowsiness, and increased analgesic requirement. A nonopioid anesthesia technique may reduce morbidity, enable day care surgery, and possibly decrease tumor recurrence. We compared opioid-free, nerve block-based anesthesia with opioid-based general anesthesia for breast cancer surgery in a prospective cohort study. Material and Methods: Twenty four adult American Society of Anesthesiologists grade I-III patients posted for modified radical mastectomy (MRM) with axillary dissection were induced with propofol and maintained on isoflurane (0...
January 2018: Journal of Anaesthesiology, Clinical Pharmacology
https://www.readbyqxmd.com/read/29619054/clinical-analysis-of-speculum-based-vaginal-packing-for-high-dose-rate-intracavitary-tandem-and-ovoid-brachytherapy-in-cervical-cancer
#6
Shivani Sud, Toni Roth, Ellen Jones
Purpose: Intra-vaginal packing is used to fix the applicator and displace organs at risk (OAR) during high-dose-rate intracavitary tandem and ovoid brachytherapy (HDR-ICB). We retain the speculum from applicator placement as a dual-function bladder and rectum retractor during treatment. Our objective is to review salient techniques for OAR displacement, share our packing technique, and determine the reduction in dose to OAR and inter-fraction variability of dose to OAR, associated with speculum-based vaginal packing (SBVP) in comparison to conventional gauze packing during HDR-ICB...
February 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29597048/screening-for-canine-transitional-cell-carcinoma-tcc-by-sers-based-quantitative-urine-cytology
#7
Alessia Pallaoro, Rustin Y Mirsafavi, William T N Culp, Gary B Braun, Carl D Meinhart, Martin Moskovits
Canine lower urinary tract neoplasia is a clinically important disease process that has high mortality due to late stage diagnosis and poorly durable response to treatment. Non-invasive diagnostic techniques (e.g. dipstick test, urine cytology) currently have poor diagnostic value, while more invasive tests (e.g. cystoscopy and biopsy) are costly and often require general anesthesia. We have developed and herein describe a quantitative cytological analysis method based on the use of surface-enhanced Raman spectroscopy (SERS), for identifying cancerous transitional cells in urine using SERS biotags (SBTs) carrying the peptide PLZ4 (amino acid sequence cQDGRMGFc) that targets malignant transitional cells...
March 26, 2018: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/29595039/an-update-on-prostate-biopsy-in-the-era-of-magnetic-resonance-imaging
#8
Antonio Cicione, Cosimo DE Nunzio, Stefano Manno, Rocco Damiano, Alessandro Posti, Estevao Lima, Andrea Tubaro, Filippo Balloni
INTRODUCTION: Prostate cancer (PCa) is a singular disease owing to absence of imaging technique able to detect suspicious glandular area at higher risk of disease. Nowadays, Magnetic Resonance Imaging (MRI) has been used as a way to detect PCa and simplify targeting prostate biopsy (PB). The aim of this study is to review the most recent data regarding prostate biopsy and MRI guided PB. EVIDENCE ACQUISITION: A comprehensive systematic MEDLINE search was performed in December 2017 for English language reports by using the following terms: prostate biopsy, multiparametric magnetic resonance imaging, prostate cancer, transrectal and transperineal ultrasound, target biopsy...
March 28, 2018: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/29593433/mechanical-ventilation-promotes-lung-metastasis-in-experimental-4t1-breast-cancer-lung-metastasized-models
#9
Yinglai Huang, Lin Pan, Khalil Helou, Qisheng Xia, Toshima Z Parris, Hongyan Li, Bo Xu, Hon Li
Background/purpose: The aim of this study was to test the hypothesis that mechanical ventilation (MV) during cancer surgery induces lung stroma/tissue milieu changes, creating a favorable microenvironment for postoperative lung metastatic tumor establishment. Materials and methods: In Protocol A, female BALB/c mice were divided into an MV group and a control (no MV) group, both of which were anesthetized and subjected to intravenous injection of green fluorescent protein (GFP)-labeled mouse mammary carcinoma cell line (4T1) cells...
2018: Cancer Management and Research
https://www.readbyqxmd.com/read/29590739/gastrostomy-under-paravertebral-block-in-high-risk-patients-with-esophageal-cancer-two-case-reports
#10
Miroslav Zupčić, Anđelko Korušić, Stjepan Barišin, Jasminka Peršec, Igor Nikolić, Sandra Graf Zupčić, Vjekoslav Jeleč, Viktor Đuzel, Zlatko Vlajčić
Here we present two cases of gastrostomy insertion via laparotomy in patients with malignant esophageal disease. Patients were ASA (American Society of Anesthesiologists) physical status III and IV. The patients presented as very high risk for general anesthesia, so we decided to use unilateral left sided paravertebral block (PVB) on four thoracic levels along with contralateral local infiltration at the gastrostomy insertion site. We present two cases, one of them a 57-year-old male ASA III patient scheduled for a gastrostomy procedure due to esophageal cancer with infiltration of the trachea...
December 2017: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29578176/applications-of-nerve-stimulator-guided-thoracic-paravertebral-nerve-block-plus-general-anesthesia-in-small-incision-lung-cancer-surgery
#11
Pengfei Lei, Shan Gao, Peishan Wang, Jiefang Fan, Xiting Ai
Objective: The aim of the study was to investigate the application of nerve stimulator-guided thoracic paravertebral nerve block (TPVB) plus general anesthesia (GA) in small-incision lung cancer surgery. Methods: Forty patients scheduled for small-incision lung cancer surgery, the American Society of Anesthesiologists Grade I-II, were randomized into a TPVB-GA group (Group P) and a GA group (Group G), with 20 cases in each group. The dosage of general anesthetic, mean arterial pressure (MAP) at each time point, and heart rate (HR) of the two groups were recorded...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29570154/isoflurane-impacts-murine-melanoma-growth-in-a-sex-specific-immune-dependent-manner-a-brief-report
#12
Angela Meier, Emilie T E Gross, Jan M Schilling, Ruth Seelige, Yujin Jung, Endi Santosa, Stephen Searles, Tuo Lin, Xin M Tu, Hemal H Patel, Jack D Bui
The impact of volatile anesthetics on cancer progression has been observed for decades, but sex differences have not been described. Male and female immune systems vary considerably, and the immune system plays an important role in limiting cancer growth. Currently, mouse models describing the impact of volatile anesthetics on cancer growth are limited to same-sex models. In this brief report, we describe a sex-specific impact of isoflurane on melanoma growth observed in wild-type but not in immune-deficient mice...
March 21, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29565951/effect-of-dexmedetomidine-added-to-modified-pectoral-block-on-postoperative-pain-and-stress-response-in-patient-undergoing-modified-radical-mastectomy
#13
Mohamed A Bakr, Sahar A Mohamed, Mohamad F Mohamad, Montaser A Mohamed, Fatma A El Sherif, Eman Mosad, Mohammed F Abdel-Hamed
BACKGROUND: The most common surgical procedure for breast cancer is the modified radical mastectomy (MRM), but it is associated with significant postoperative pain. Regional anesthesia can reduce the stress response associated with surgical trauma. OBJECTIVES: Our aim is to explore the efficacy of 1 µg/kg dexmedetomedine added to an ultrasound (US)-modified pectoral (Pecs) block on postoperative pain and stress response in patients undergoing MRM. STUDY DESIGN: A randomized, double-blind, prospective study...
March 2018: Pain Physician
https://www.readbyqxmd.com/read/29557825/robotic-vs-open-surgery-for-endometrial-cancer-in-elderly-patients-surgical-outcome-survival-and-cost-analysis
#14
Anna Lindfors, Åsa Åkesson, Christian Staf, Per Sjöli, Karin Sundfeldt, Pernilla Dahm-Kähler
OBJECTIVE: This study aimed to compare robotic and open surgery in elderly women diagnosed as having endometrial cancer, in terms of costs, survival, surgical outcome, and operating time. METHODS: Women 70 years or older undergoing open and robotic surgery for endometrial cancers were included consecutively before and after the introduction of robotic surgery at a tertiary center. Costs were calculated using the case-costing system, cost per patient, including the first 30 postoperative days...
March 20, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29556272/primary-non-hodgkin-s-lymphoma-of-the-vagina-a-case-report
#15
Feng Wang, Xuquan Jing, Bo Liu, Xue Meng, Xindong Sun, Yongsheng Gao, Linlin Wang, Zheng Fu
Primary non-Hodgkin's lymphoma (NHL) of the vagina is uncommon. The present case study reports the case of a 54-year-old female with a palpable mass between the rectum and vagina. The patient presented with symptoms consistent with vaginal cancer but lacked any of the 'B' symptoms often associated with systemic lymphoma, including fever, weight loss, night sweats and fatigue. The mass was resected under anesthesia. Immunohistochemistry and biopsy confirmed diffuse large B-cell NHL (DLBCL). Following surgery, six cycles of chemotherapy with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone were administered...
March 2018: Oncology Letters
https://www.readbyqxmd.com/read/29552803/cervical-cancer-in-the-work-of-the-unconventional-samuel-pozzi-1846-1918-pioneer-of-modern-gynaecology
#16
Marianna Karamanou, Achilleas Drogosis, Nikolaos Salakos, Kostas Markatos, Efthimios Deligeoroglou, George Androutsos
Advocate of Lister's antiseptic techniques, promoter of anesthesia, professor of the first chair of gynaecology in Medical School of Paris, academician, successful politician, art collector, friend and lover of the famous, Samuel Pozzi lived a fascinating life. His book "Treatise of clinical and surgical gynaecology" published in 1890 became the gold standard in medical practice while his approach in the treatment of cervical cancer, including cases of pregnant women, remained in vogue for almost fifty years...
January 2018: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/29535538/effects-of-propofol-based-total-intravenous-anesthesia-on-gastric-cancer-a-retrospective-study
#17
Xiaoyu Zheng, Yu Wang, Linlin Dong, Su Zhao, Liping Wang, Hong Chen, Yang Xu, Guonian Wang
Background: Several kinds of cancer surgeries with propofol-based total intravenous anesthesia (TIVA) have been shown to have better outcomes than those with sevoflurane-based inhalational anesthesia (INHA). However, the effects of this anesthetic technique have not been investigated in patients with gastric cancer. In this study, the authors retrospectively examined the link between the choice of anesthetic technique and overall survival in patients undergoing gastric cancer resection...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29534384/-study-of-comparing-dexmedetomidine-and-remifentanil-for-conscious-sedation-during-radiofrequency-ablation-of-hepatocellular-carcinoma
#18
H T Sun, M Xu, G L Chen, J He
Objective: This study aimed to compare dexmedetomidine with remifentanil for conscious sedation in patients undergoing radiofrequency ablation of hepatocellular carcinoma. Methods: Sixty patients, who were aged 41 to 73 years with American Society of Anesthesiologists (ASA) physical status Ⅰ-Ⅱ, and scheduled for elective radiofrequency ablation of hepatocellular carcinoma under conscious sedation in National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, from January 2014 to June 2016, were allocated randomly to receive dexmedetomidine maintenance regimen(group D, n =30)or remifentanil maintenance regimen(group R, n =30)by random digital table...
February 27, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29527466/identifying-quality-improvement-targets-to-facilitate-colorectal-cancer-screening-completion
#19
Simon J Craddock Lee, Stephen J Inrig, Bijal A Balasubramanian, Celette Sugg Skinner, Robin T Higashi, Katharine McCallister, Wendy Pechero Bishop, Noel O Santini, Jasmin A Tiro
The colorectal cancer (CRC) screening process involves multiple interfaces (communication exchanges and transfers of responsibility for specific actions) among primary care and gastroenterology providers, laboratory, and administrative staff. After a retrospective electronic health record (EHR) analysis discovered substantial clinic variation and low CRC screening prevalence overall in an urban, integrated safety-net system, we launched a qualitative analysis to identify potential quality improvement targets to enhance fecal immunochemical test (FIT) completion, the system's preferred screening modality...
March 2018: Preventive Medicine Reports
https://www.readbyqxmd.com/read/29526348/interventions-in-the-operating-room-for-children-near-end-of-life-a-multidisciplinary-approach
#20
Marianne Goudreault, Nago Humbert, France Gauvin, Monia Marzouki, Catherine K Beaumier, Dickens St-Vil, Nelson Piché
INTRODUCTION: Pediatric surgeons are often involved in the management of severely or terminally ill patients. However, articles addressing their specific roles in the context of palliative care are almost inexistent. We sought to characterize the involvement of pediatric surgeons caring for children near end of life. METHODS: Chart review of children who had a procedure under general anesthesia within 6months of their death over a five-year period at a tertiary children's hospital (excluding traumas and neonatology cases)...
February 9, 2018: Journal of Pediatric Surgery
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