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I A Nasir, A Owolagba, A E Ahmad, M M Barma, P O Musa Po, M Bakare, Y Ibrahim, D O Amadu
BACKGROUND: Blood coagulation abnormalities are common in persons infected with the human immunodeficiency virus (HIV). However, few studies showed the association of these abnormalities with anti-retroviral therapy (ART). OBJECTIVE: This cross-sectional study investigated the effects of ART on blood coagulation parameters of patients infected with HIV attending HIV special clinics of the University of Abuja Teaching Hospital (UATH), Gwagwalada, Abuja, Nigeria. MATERIAL AND METHODS: A total of 191 patients comprising 128 HIV subjects on ART (test subjects) and 63 other HIV patients not on ART (control subjects) were included in the study...
August 2016: Malaysian Journal of Pathology
Richard A Heipertz, Ojor Ayemoba, Eric Sanders-Buell, Kultida Poltavee, Phuc Pham, Gustavo H Kijak, Esther Lei, Meera Bose, Shana Howell, Anne Marie OʼSullivan, Adam Bates, Taylor Cervenka, Janelle Kuroiwa, Akindiran Akintunde, Onyekachukwu Ibezim, Abraham Alabi, Obumneke Okoye, Mark Manak, Jennifer Malia, Sheila Peel, Mohammed Maisaka, Darrell Singer, Robert J O'Connell, Merlin L Robb, Jerome H Kim, Nelson L Michael, Ogbonnaya Njoku, Sodsai Tovanabutra
While abundant sequence information is available from human immunodeficiency virus type 1 (HIV-1) subtypes A, B, C and CRF01_AE for HIV-1 vaccine design, sequences from West Africa are less represented. We sought to augment our understanding of HIV-1 variants circulating in 6 Nigerian cities as a step to subsequent HIV-1 vaccine development.The G/CRF02_AG multi-region hybridization assay (MHA) was developed to differentiate subtype G, CRF02_AG and their recombinants from other subtypes based on 7 HIV-1 segments...
August 2016: Medicine (Baltimore)
Lukman Adewale Alli
This study was designed to assess the blood levels of cadmium and lead in some occupationally exposed individuals and compare the values with non-exposed individuals, with the aim of increasing the awareness of health risk caused by these heavy metals. A total of 120 subjects (64 occupationally exposed and 56 non-exposed subjects) with the age range of 15-40 years were studied in cross-sectional study conducted between September 2012 and February 2013 in Gwagwalada area of Abuja, Nigeria. Blood cadmium and lead were analyzed using an atomic absorption spectrophotometer (AAS)...
September 2015: Interdisciplinary Toxicology
Godwin Akaba, Nathaniel Ketare, Wilfred Tile
OBJECTIVES: To investigate the knowledge, attitudes, and extent of involvement of men in family planning in Nigeria, and to evaluate spousal communication regarding family planning. METHODS: A community-based, mixed-methods study enrolled participants in Gwagwalada, Abuja, Nigeria between January 11 and June 30, 2012. Quantitative surveys including semi-structured interviews were used to collect information from married men regarding their knowledge and attitudes to modern family planning...
October 2016: International Journal of Gynaecology and Obstetrics
P U Ibekwe, T S Ibekwe
Allergic rhinitis (AR) is prevalent in Nigeria, though little information exists on the allergen. We assessed the clinical features of AR patients in our environment based on the allergic rhinitis impact on asthma (ARIA) classification. Only patients with positive skin prick test (SPT) were recruited. Seventy-four patients participated in the study. AR and asthma comorbidity were observed in 13.5%. The proportion of "sneezers-runners" was higher than "blockers" with significantly more "sneezers-runners" having persistent AR (P = 0...
2016: Journal of Allergy
Shauna Stahlman, Rebecca G Nowak, Hongjie Liu, Trevor A Crowell, Sosthenes Ketende, William A Blattner, Manhattan E Charurat, Stefan D Baral
The TRUST/RV368 project was undertaken to apply innovative strategies to engage Nigerian MSM into HIV care. In this analysis we evaluate characteristics of online sex-seekers from the TRUST/RV368 cohort of 1370 MSM in Abuja and Lagos. Logistic regression and generalized estimating equation models were used to assess associations with online sex-seeking. Online sex-seeking (n = 843, 61.5 %) was associated with participation in MSM community activities, larger social and sexual networks, and higher levels of sexual behavior stigma...
May 27, 2016: AIDS and Behavior
Chukwuedozie K Ajaero, Clifford Odimegwu, Ijeoma D Ajaero, Chidiebere A Nwachukwu
BACKGROUND: Nigeria has the highest population in sub-Saharan Africa with high birth and growth rates. There is therefore need for family planning to regulate and stabilize this population. This study examined the relationship between access to mass media messages on family planning and use of family planning in Nigeria. It also investigated the impacts of spatio-demographic variables on the relationship between access to mass media messages and use of family planning. METHODS: Data from the 2013 demographic and health survey of Nigeria which was conducted in all the 36 states of Nigeria, and Abuja were used for the study...
2016: BMC Public Health
K C Iregbu, P I Nwajiobi-Princewill
BACKGROUND: Hepatitis B viral infection is an old medical problem with worldwide distribution. It is usually diagnosed using serologic methods. However, the decision as to which patient to treat or not remains challenging due to the poor sensitivity of serologic markers as prognostic or severity markers. Viral load (VL) determination using polymerase chain reaction techniques is a useful tool in decision-making. AIM: To determine the proportion of hepatitis B-positive patients who fall into different care groups based on the Society for Gastroenterology and Hepatology in Nigeria (SOGHIN) and National Institute for Health and Care Excellence guidelines, respectively, using result of hepatitis B virus (HBV) DNA determination...
March 2016: Annals of Medical and Health Sciences Research
Bioku Muftau Jimoh, Ikuerowo Stephen Odunayo, Igwilo Chinwe, Omisanjo Olufunmilade Akinfolarin, Adewumi Oluwafemi, Esho Julius Olusanmi
INTRODUCTION: The World Health Organization's manual on male circumcision listed Plastibell technique as a well-proven paediatric method with respect to the results and complications. Although, literatures abound on its wide acceptability, there are few multi-centered reports from this environment. The objective was to evaluate the cases of infant circumcision by Plastibell device from two medical institutions. METHODS: All consecutive infants who had Classical Plastibell Circumcision (PC) at the Federal Staff Medical Centre, Abuja and the Lagos State University Teaching Hospital, Ikeja between February 2011 and June 2015 were included in this cross-sectional study...
2016: Pan African Medical Journal
Emeka Chukwu, Lalit Garg, Godson Eze
BACKGROUND: Nigeria contributes only 2% to the world's population, accounts for 10% of the global maternal death burden. Health care at primary health centers, the lowest level of public health care, is far below optimal in quality and grossly inadequate in coverage. Private primary health facilities attempt to fill this gap but at additional costs to the client. More than 65% Nigerians still pay out of pocket for health services. Meanwhile, the use of mobile phones and related services has risen geometrically in recent years in Nigeria, and their adoption into health care is an enterprise worth exploring...
2016: JMIR MHealth and UHealth
Dike B Ojji, Sandrine Lecour, John J Atherton, Lori A Blauwet, Jacob Alfa, Karen Sliwa
INTRODUCTION: Right ventricular (RV) systolic dysfunction is now recognized widely as a strong and independent predictor of adverse outcomes in patients with heart failure (HF). Reduction of RV systolic function more closely predicts impaired exercise tolerance and poor survival than does left ventricular (LV) systolic function. In spite of this, there is a dearth of data on RV function in hypertensive HF which is the commonest form of HF in sub-Saharan Africa. We therefore conducted a prospective cohort study of hypertensive HF patients presenting to the University of Abuja Teaching Hospital, Abuja, Nigeria over an 8 year period...
2016: PloS One
Abiodun D Olusesi, J Abubakar
The clinician's major role in management of the dizzy patient involves determining what dizziness is vertigo, and what vertigo is of central or peripheral origin. These demand attention to details of history, otolaryngological workup including vestibular assessment, and often use of diagnostic and management algorithms. There is paucity of published reports of the management outcomes of peripheral vestibular diseases from Africa. Two tertiary care otologist-led dedicated vertigo clinics are located in Abuja, Nigeria...
March 9, 2016: European Archives of Oto-rhino-laryngology
Binyerem C Ukaire, Chris O Agboghoroma, Korede W Durojaiye
Rapid HIV test in labour provide an opportunity for the identification of HIV positive pregnant women who should benefit from interventions to reduce the risk of mother-to-child transmission (MTCT) of HIV. Between November 2013 and June 2014 we conducted rapid HIV testing of pregnant women in labour at the National Hospital Abuja to determine the HIV seroconversion rate in pregnancy and the prevalence of HIV in pregnant women in labour with previously unknown status. HIV testing and counseling (HTC) was acceptable to 224 (99...
September 2015: African Journal of Reproductive Health
Gbemisola Magaret Olabanji, Beatty Viv Maikai, Gbeminiyi Richard Otolorin
Cryptosporidium is one of the causes of diarrhoeal illness in man and animals worldwide. The aim of the study was to determine the prevalence and risk factors associated with faecal shedding of Cryptosporidium oocysts in dogs in FCT Abuja, Nigeria. A total of 276 dog faecal samples were examined using Modified Acid Fast (MAF) technique and Enzyme Linked Immunosorbent Assay (ELISA). Fifteen (5.4%) and 51 (18.5%) out of the 276 dog faecal samples examined were positive for Cryptosporidium oocysts and coproantigens, respectively...
2016: Veterinary Medicine International
Idris Abdullahi Nasir, Abdurrahman Elfulaty Ahmad, Anthony Uchenna Emeribe, Muhammad Sagir Shehu, Jessy Thomas Medugu, Adamu Babayo
BACKGROUND: Individuals with human T-cell lymphotrophic virus type-1 (HTLV-1)/HIV-1 coinfection have been demonstrated to undergo CD4+ lymphocytosis even in the face of immunodeficiency and increased vulnerability to opportunistic pathogens that can lead to poor prognosis. OBJECTIVE: This study investigated the prevalence as well as the effects of HIV-1/HTLV-1 coinfection on CD4+ cell counts, routine hematology, and biochemical parameters of study participants. MATERIALS AND METHODS: This prospective cross-sectional study involved 184 blood samples collected from HIV-1-seropositive individuals attending HIV-special clinic of the University of Abuja Teaching Hospital, Gwagwalada, Nigeria...
2015: Virology: Research and Treatment
Abigail U Emelonye, Taina Pitkäaho, Katri Vehviläinen-Julkunen
Background. Measures of spousal effect during parturient pain should take a tripartite approach involving the parturients, spouses, and midwives. Aim. To develop and validate three questionnaires measuring spousal presence in management of parturient pain in Nigeria. Methods. There are two phases: (1) development of questionnaires, Abuja Instrument for Midwives (AIM), Abuja Instrument for Parturient Pain (AIPP), and Abuja Instrument for Parturient Spouses (AIPS), utilizing literatures, Kuopio instrument for fathers (KIF) and expertise of health professionals, and (2) pilot study to validate the questionnaires which were administered in two hospitals in Nigeria: midwives (n = 10), parturients (n = 10), and spouses (n = 10)...
2015: Nursing Research and Practice
Olukunmi O Balogun, Satomi Kobayashi, Kola M Anigo, Erika Ota, Keiko Asakura, Satoshi Sasaki
PURPOSE: To determine the association between prenatal exclusive breastfeeding intentions and exclusive breastfeeding (EBF) and explore other factors associated with EBF until 3 months postpartum among mothers residing in suburban parts of the Federal Capital Territory, Abuja Nigeria. DESCRIPTION: This longitudinal observational study involved the recruitment of 210 pregnant women who were prospectively followed until 3 months postpartum. Participants were recruited from antenatal clinics attached to four separate public secondary health facilities located in the suburban parts of Abuja...
February 2016: Maternal and Child Health Journal
Bola I Udegbe, Funke Fayehun, Uche C Isiugo-Abanihe, Williams Nwagwu, Ifeoma Isiugo-Abanihe, Ezebunwa Nwokocha
Family Life and HIV Education (FLHE) programme was introduced nationwide in Nigeria in 2003. Since then little is known about the patterns of its implementation across the states in the six geo-political zones in Nigeria. This study represents an attempt to fill this lacuna in the FLHE literature in Nigeria. Quantitative data was collected from the Federal Ministry of Education and the State Ministries of Education on all salient aspects of FLHE implementation. The findings from data collected in 35 states and the Abuja Federal Capital Territory show large variations in the year of adoption of the programme, level of implementation of the programme, the proportion of implementing schools that are reporting to the coordinating government ministries/agencies, the level to which schools have been supplied with relevant curriculum, and promptness of distribution of materials across the zones...
June 2015: African Journal of Reproductive Health
Dike B Ojji, Elena Libhaber, John J Atherton, Bolaji Abdullahi, Ada Nwankwo, Karen Sliwa
Risk factors, comorbidities, and end-organ damage in newly diagnosed hypertension (HT) are poorly described in larger cohorts of urban African patients undergoing epidemiological transition. We therefore decided to characterize a large cohort of hypertensive subjects presenting to a tertiary health center in sub-Saharan Africa. It is an observational cross-sectional study. We prospectively collected detailed clinical, biochemical, electrocardiography, and echocardiography data of all subjects with HT as the primary diagnosis in patients presenting at the Cardiology Unit of the University of Abuja Teaching Hospital over an 8-year period...
September 2015: Medicine (Baltimore)
Titus S Ibekwe, David O Folorunsho, Enoch A Dahilo, Ibeneche O Gbujie, Maxwell M Nwegbu, Onyekwere G Nwaorgu
Noise is a global occupational and environmental health hazard with considerable social and physiological impact and, therefore, there is a need for regular measurements to boost monitoring and regulations of environmental noise levels in our communities. This necessitates a readily available, inexpensive, and easy to use noise measuring device. We aimed to test the sensitivity and validity of mobile "smart" phones for this purpose. This was a comparative analysis of a cross sectional study done between January 2014 and February 2015...
2016: Journal of Occupational and Environmental Hygiene
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