Antonia Jaqueline Nobre Bezerra, Francisca Crislândia Oliveira Silva, Antonio Wlisses da Silva, Maria Kueirislene Amâncio Ferreira, Emanuelle Machado Marinho, Márcia Machado Marinho, Francisco Ernani Alves Magalhães, Paulo Nogueira Bandeira, Alexandre Magno Rodrigues Teixeira, Emmanuel Silva Marinho, Jane Eire Silva Alencar de Menezes, Hélcio Silva Dos Santos
Croton zehntneri is a plant known as canelinha de cunhã, prevalent in the northeast region of Brazil. Many constituents of the vegetable have already been studied, and their pharmacological properties have been proven, but this is the first study to analyze the antinociceptive effect in adult zebrafish (ZFa) of the triterpene acetyl aleuritolic acid (AAA) isolated from the stem bark. The animals (ZFa; n = 6/group) were treated intraperitoneally (ip; 20 μL) with AAA (0.1 or 0.3 or 1.0 mg/mL) or vehicle (0...
January 1, 2021: Biochemical and Biophysical Research Communications