keyword
MENU ▼
Read by QxMD icon Read
search

Self ligation

keyword
https://www.readbyqxmd.com/read/28902253/bacterial-adhesion-on-conventional-and-self-ligating-metallic-brackets-after-surface-treatment-with-plasma-polymerized-hexamethyldisiloxane
#1
Rogerio Amaral Tupinambá, Cristiane Aparecida de Assis Claro, Cristiane Aparecida Pereira, Celestino José Prudente Nobrega, Ana Paula Rosifini Alves Claro
Introduction: Plasma-polymerized film deposition was created to modify metallic orthodontic brackets surface properties in order to inhibit bacterial adhesion. Methods: Hexamethyldisiloxane (HMDSO) polymer films were deposited on conventional (n = 10) and self-ligating (n = 10) stainless steel orthodontic brackets using the Plasma-Enhanced Chemical Vapor Deposition (PECVD) radio frequency technique. The samples were divided into two groups according to the kind of bracket and two subgroups after surface treatment...
July 2017: Dental Press Journal of Orthodontics
https://www.readbyqxmd.com/read/28895232/anion-directed-metallocages-a-study-on-the-tendency-of-anion-templation
#2
Jing-Yun Wu, Ming-Shiou Zhong, Ming-Hsi Chiang
Self-assembly of Cu(NO3)2∙3H2O and a di(3-pyridylmethyl)amine (dpma) ligand with addition of different acids (HNO3, HOAc, HCl, HClO4, HOTf, HPF6, HBF4, and H2SO4) afforded a family of anion-templated tetragonal metallocages having a cationic prismatic structure of [(Gn-){Cu2(Hdpma)4}](8-n)+ (Gn- = NO3-, PF6-, SiF62-) with different ligating anions/solvents (NO3-, Cl-, ClO4-, OTf-, H2O) outside the cage. The systematic competitive experiments have significantly rationalized a tendency of anion templation towards the formation of metallocages [(Gn-){Cu2(Hdpma)4}](8-n)+ as SiF62- ~ PF6- > NO3- > SO42- ~ ClO4- ~ BF4-...
September 12, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28839474/oxidative-stress-evaluation-in-patients-treated-with-orthodontic-self-ligating-multibracket-appliances-an-in-vivo-case-control-study
#3
Marco Portelli, Angela Militi, Gabriele Cervino, Floriana Lauritano, Sergio Sambataro, Alberto Mainardi, Riccardo Nucera
OBJECTIVE: Oxidative stress is a pathologic event induced by a prevalence of oxidant agents on the antioxidant ones, with a consequent alteration of oxide-reducing balance. INTRODUCTION: Freeradicals produce damages both in cellular and extra-cellular components; phospholipid membranes, proteins, mitochondrial and nuclear DNA, are the target of the oxidative stress, that can finally cause cellular death due to apoptosis. MATERIALS & METHODS: Orthodontic appliances such as brackets, wires, resins and soldering have some components that can be considered as potential allergen, carcinogenic, cytotoxic and gene mutation factors...
2017: Open Dentistry Journal
https://www.readbyqxmd.com/read/28816368/one-pot-self-assembly-of-peptide-based-cage-type-nanostructures-using-orthogonal-ligations
#4
Eline Bartolami, Jérémie Knoops, Yannick Bessin, Mathieu Fossépré, Joseph Chamieh, Pascal Dumy, Mathieu Surin, Sebastien Ulrich
The designed arrangement of biomolecular entities within monodisperse nanostructures is an important challenge toward functional biomaterials. We report herein a method for the formation of water-soluble peptide-based cages using orthogonal ligation reactions - acylhydrazone condensation and thiol-maleimide addition. The results show that using pre-organized cyclic peptides and heterobifunctional spacers as building blocks and a set of orthogonal and chemoselective ligation reactions enable cage formation in one-pot from six components and through eight reactions...
August 17, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28816185/an-in-vitro-evaluation-of-friction-characteristics-of-conventional-stainless-steel-and-self-ligating-stainless-steel-brackets-with-different-dimensions-of-archwires-in-various-bracket-archwire-combination
#5
K Sridharan, Shailesh Sandbhor, U B Rajasekaran, George Sam, M Mohamed Ramees, Esther A Abraham
AIM: The purpose of this research is to compare the frictional attributes of stainless steel conventional brackets and self-ligating stainless steel brackets with different dimensions of archwires. MATERIALS AND METHODS: The test was carried with two sets of maxillary brackets: (1) Conventional stainless steel (Victory Series), (2) stainless steel self-ligating (SmartClip) without first premolar brackets. Stainless steel, nickel-titanium (NiTi), and beta-Ti which are the types of orthodontic wire alloys were tested in this study...
August 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28802784/a-hybrid-straightwire-technique
#6
Daniel Celli, Lorenza Catalfamo, Enrico Gasperoni, Roberto Deli
An original straightwire appliance was developed in order to easily adapt force and friction to the different stages and needs of treatment. The appliance features: (1) conventional brackets with a 0.020×0.030″ slot in the anterior area, passive self-ligating brackets with a 0.022×0.030″ slot in the lateral area, and tubes with a 0.022×0.030″ slot in the molar area; (2) archwires which adapt to the different stages of treatment and increase their section and stiffness progressively, starting with 0...
August 10, 2017: International Orthodontics
https://www.readbyqxmd.com/read/28773852/design-of-decorated-self-assembling-peptide-hydrogels-as-architecture-for-mesenchymal-stem-cells
#7
Annj Zamuner, Marta Cavo, Silvia Scaglione, Grazia Maria Lucia Messina, Teresa Russo, Antonio Gloria, Giovanni Marletta, Monica Dettin
Hydrogels from self-assembling ionic complementary peptides have been receiving a lot of interest from the scientific community as mimetic of the extracellular matrix that can offer three-dimensional supports for cell growth or can become vehicles for the delivery of stem cells, drugs or bioactive proteins. In order to develop a 3D "architecture" for mesenchymal stem cells, we propose the introduction in the hydrogel of conjugates obtained by chemoselective ligation between a ionic-complementary self-assembling peptide (called EAK) and three different bioactive molecules: an adhesive sequence with 4 Glycine-Arginine-Glycine-Aspartic Acid-Serine-Proline (GRGDSP) motifs per chain, an adhesive peptide mapped on h-Vitronectin and the growth factor Insulin-like Growth Factor-1 (IGF-1)...
August 26, 2016: Materials
https://www.readbyqxmd.com/read/28760641/maternal-alterations-induced-by-exposure-to-an-unfamiliar-home-cage-in-early-underfed-dams
#8
Manuel Salas, Mirelta Regalado, Carmen Torrero, Lorena Rubio
The expression of different behavioral components in the adult rat depends on a number of early influences, including age, hormones, manipulations of sensory cues, and perinatal undernutrition, all of which impact the development of brain areas underlying adaptive processes, maternal behavior, and the response to novelty. The current study investigates the effects of pre- and neonatal undernutrition on various components of maternal behavior of dams exposed to the challenge of an unfamiliar home cage on days 4, 8, and 12 of lactation...
July 29, 2017: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/28742097/mrtadfinder-a-network-modularity-based-approach-to-identify-topologically-associating-domains-in-multiple-resolutions
#9
Koon-Kiu Yan, Shaoke Lou, Mark Gerstein
Genome-wide proximity ligation based assays such as Hi-C have revealed that eukaryotic genomes are organized into structural units called topologically associating domains (TADs). From a visual examination of the chromosomal contact map, however, it is clear that the organization of the domains is not simple or obvious. Instead, TADs exhibit various length scales and, in many cases, a nested arrangement. Here, by exploiting the resemblance between TADs in a chromosomal contact map and densely connected modules in a network, we formulate TAD identification as a network optimization problem and propose an algorithm, MrTADFinder, to identify TADs from intra-chromosomal contact maps...
July 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28736216/pathogen-induced-tlr4-trif-innate-immune-signaling-in-hematopoietic-stem-cells-promotes-proliferation-but-reduces-competitive-fitness
#10
Hitoshi Takizawa, Kristin Fritsch, Larisa V Kovtonyuk, Yasuyuki Saito, Chakradhar Yakkala, Kurt Jacobs, Akshay K Ahuja, Massimo Lopes, Annika Hausmann, Wolf-Dietrich Hardt, Álvaro Gomariz, César Nombela-Arrieta, Markus G Manz
Bacterial infection leads to consumption of short-lived innate immune effector cells, which then need to be replenished from hematopoietic stem and progenitor cells (HSPCs). HSPCs express pattern recognition receptors, such as Toll-like receptors (TLRs), and ligation of these receptors induces HSPC mobilization, cytokine production, and myeloid differentiation. The underlying mechanisms involved in pathogen signal transduction in HSCs and the resulting biological consequences remain poorly defined. Here, we show that in vivo lipopolysaccharide (LPS) application induces proliferation of dormant HSCs directly via TLR4 and that sustained LPS exposure impairs HSC self-renewal and competitive repopulation activity...
August 3, 2017: Cell Stem Cell
https://www.readbyqxmd.com/read/28727574/flexible-ligated-ruthenium-ii-self-assemblies-sensitizes-glioma-tumor-initiating-cells-in-vitro
#11
Palani Elumalai, Neha Kaushik, Dong Hwan Kim, Hyunuk Kim, Su Jae Lee, Eun Ha Choi, Ki-Whan Chi, Nagendra Kumar Kaushik
The tumorigenic potentials of residual cancer stem-like cells within tumors represent limitations of current cancer therapies. Here, the authors describe the effects of synthesized flexible, ligated, supramolecular self-assembled chair type tetranuclear ruthenium (II) metallacycles (2-5) on glioblastoma and glioma stem like cells. These self-assemblies were observed to be selectively toxic to glioma cells and CD133-positive glioma stem like cells population. Of the self-assembled compounds tested, metallacycle 4 more efficiently induced glioma stem like cells death within a brain cancer cell population and simultaneously inhibited the formation of free-floating gliospheres by reducing the sphere size...
July 5, 2017: Oncotarget
https://www.readbyqxmd.com/read/28709866/mesenchymal-stem-cell-transplantation-carried-in-svvyglr-modified-self-assembling-peptide-promoted-cardiac-repair-and-angiogenesis-after-myocardial-infarction
#12
Xi-Ren Gao, Hai-Jun Xu, Li-Fang Wang, Chong-Bin Liu, Feng Yu
The efficiency of stem cell therapy for myocardial infarction (MI) was very low due to the hostile microenvironment and poor blood perfusion. In this study, we designed a new self-assembling peptide through adding angiogenic polypeptide SVVYGLR to the carboxyl terminal of RADA16, and evaluated the therapeutic potential of mesenchymal stem cell (MSC) transplantation carried in this designer self-assembling peptide (DSP) on MI. After the model of cell ischemia and hypoxia was established in vitro, cytoprotective effect of DSP on MSC was detected by AO/EB staining...
September 9, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28691142/force-level-of-small-diameter-nickel-titanium-orthodontic-wires-ligated-with-different-methods
#13
Rodrigo Hitoshi Higa, José Fernando Castanha Henriques, Guilherme Janson, Murilo Matias, Karina Maria Salvatore de Freitas, Fernanda Pinelli Henriques, Manoela Fávaro Francisconi
BACKGROUND: The aim of this study was to compare the deflection force in conventional and thermally activated nickel-titanium (NiTi) wires in passive (Damon Q) and active (Bioquick) self-ligating brackets (SLB) and in conventional brackets (CB) tied by two different methods: elastomeric ligature (EL) and metal ligature (ML). METHODS: Two wire diameters (0.014 and 0.016 in.) and 10 specimens per group were used. The specimens were assembled in a clinical simulation device and tested in an Instron Universal Testing Machine, with a load cell of 10 N...
December 2017: Progress in Orthodontics
https://www.readbyqxmd.com/read/28673998/insight-into-the-mechanism-of-nonenzymatic-rna-primer-extension-from-the-structure-of-an-rna-gpppg-complex
#14
Wen Zhang, Chun Pong Tam, Travis Walton, Albert C Fahrenbach, Gabriel Birrane, Jack W Szostak
The nonenzymatic copying of RNA templates with imidazole-activated nucleotides is a well-studied model for the emergence of RNA self-replication during the origin of life. We have recently discovered that this reaction can proceed through the formation of an imidazolium-bridged dinucleotide intermediate that reacts rapidly with the primer. To gain insight into the relationship between the structure of this intermediate and its reactivity, we cocrystallized an RNA primer-template complex with a close analog of the intermediate, the triphosphate-bridged guanosine dinucleotide GpppG, and solved a high-resolution X-ray structure of the complex...
July 18, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28630624/evaluation-of-the-loading-unloading-and-permanent-deformation-of-newly-available-epoxy-resin-coated-ni-ti-wires-using-self-ligating-brackets
#15
Hazel Garro-Piña, María Cristina Jiménez-Cervantes, Ricardo Ondarza-Rovira, Roberto Justus, Salvador García-López
AIM: The purpose of this study was to evaluate the load and unload deflection and permanent deformation of round 0.016'' and rectangular 0.016'' × 0.022'' regular and coated Ni-Ti wires. MATERIALS AND METHODS: Ni-Ti archwires produced by two manufacturers were evaluated. Both regular and coated round and rectangular Ni-Ti wire segments (n = 15) from each group were submitted to a three-point bending test. Both types of wires were evaluated for permanent deformation at the end of a recovery cycle...
2017: International Journal of Dentistry
https://www.readbyqxmd.com/read/28630093/dendritic-cell-sensing-of-hydrophobic-di-and-triacylated-lipopeptides-self-assembled-within-synthetic-virus-like-particles
#16
Rajni Sharma, Arin Ghasparian, John A Robinson, Kenneth C McCullough
Dendritic cells (DCs) play critical roles in developing immune defenses. One important aspect is interaction with pathogen-associated molecular patterns (PAMPs)/danger-associated molecular patterns, including di- and triacylated lipopeptides. Isolated or synthetic lipopeptides are potent vaccine adjuvants, interacting with cell surface TLR2 heterodimers. In contrast, deep embedment within bacteria cell walls would impair lipopeptide interaction with cell surface TLR2, requiring degradation for PAMP recognition...
June 19, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28576020/polymeric-micelles-self-assembled-from-amphiphilic-polymers-with-twin-disulfides-used-as-sirna-carriers-to-enhance-the-transfection
#17
Can Yang Zhang, Shiyuan Peng, Bin Zhao, Wenji Luo, Lijuan Zhang
The sequence-defined polycationic polymers with or without Cys-Arg-Cys motifs conjugated with targeting and shielding segments were synthesized as siRNA carriers via native chemical ligation (NCL) reaction. After purification, the structures and physicochemical characteristics were determined by a variety of experimental techniques. The particle size of siRNA/CRC-polymer polyplex was much smaller than that of polyplex without CRC motifs. The buffer capacity and siRNA binding ability of CRC motifs modified polymers were significantly improved, resulting from the twin disulfides and hexatomic ring formulation...
September 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28574073/self-assembled-artificial-viral-capsids-bearing-coiled-coils-at-the-surface
#18
Seiya Fujita, Kazunori Matsuura
In order to construct artificial viral capsids bearing complementary dimeric coiled-coils on the surface, a β-annulus peptide bearing a coiled-coil forming sequence at the C-terminus (β-annulus-coiled-coil-B) was synthesized by a native chemical ligation of a β-annulus-SBn peptide with a Cys-containing coiled-coil-B peptide. Dynamic light scattering (DLS) measurements and transmission electron microscopy (TEM) images revealed that the β-annulus-coiled-coil-B peptide self-assembled into spherical structures of about 50 nm in 10 mM Tris-HCl buffer...
June 14, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/28566855/assessment-of-bracket-surface-morphology-and-dimensional-change
#19
Pillai Devu Radhakrishnan, N K Sapna Varma, V V Ajith
OBJECTIVE: The objective of this study was to compare the surface morphology and dimensional stability of the bracket slot at the onset of treatment and after 12 months of intraoral exposure. The study also compared the amount of calcium at the bracket base which indicates enamel loss among the three orthodontic brackets following debonding after 12 months of intraoral exposure. MATERIALS AND METHODS: The sample consisted of 60 (0.022" MBT) canine brackets. They were divided into three groups: self-ligating, ceramic bracket with metal slot, and stainless steel (SS) brackets...
January 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/28557448/nonclassical-single-state-reactivity-of-an-oxo-iron-iv-complex-confined-to-triplet-pathways
#20
Claudia Kupper, Bhaskar Mondal, Joan Serrano-Plana, Iris Klawitter, Frank Neese, Miquel Costas, Shengfa Ye, Franc Meyer
C-H bond activation mediated by oxo-iron (IV) species represents the key step of many heme and nonheme O2-activating enzymes. Of crucial interest is the effect of spin state of the Fe(IV)(O) unit. Here we report the C-H activation kinetics and corresponding theoretical investigations of an exclusive tetracarbene ligated oxo-iron(IV) complex, [L(NHC)Fe(IV)(O)(MeCN)](2+) (1). Kinetic traces using substrates with bond dissociation energies (BDEs) up to 80 kcal mol(-1) show pseudo-first-order behavior and large but temperature-dependent kinetic isotope effects (KIE 32 at -40 °C)...
June 22, 2017: Journal of the American Chemical Society
keyword
keyword
115516
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"