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https://www.readbyqxmd.com/read/29153019/-the-actual-questions-of-the-care-of-rare-diseases
#1
Gábor Pogány
The aim was to present the actual situation of rare diseases, especially to characterize the circumstances in Hungary. The most important developments were summarized which could help the care of rare disease patients in the everyday practice. There are around 800 000 patients with rare diseases in Hungary. The lack of information leads to "invisibility" for the health and social care system (most of them without ICD code). Therefore, these patients still have a huge disadvantage even when compared to the patients of common diseases...
November 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/29150757/invisible-side-of-emotions-somato-motor-responses-to-affective-facial-displays-in-alexithymia
#2
Cristina Scarpazza, Elisabetta Làdavas, Luigi Cattaneo
According to recent theories, the detection of emotions involves somatic experiences. In this study, we investigated the relation between somatic responses to affective stimuli, emotion perception, and alexithymia. Variations in automatic rapid facial reactions (RFRs) were measured in a selected population of participants with high and low levels of alexithymia (HA and LA, respectively). Electromyographic activity was recorded from the corrugator supercilii and the zygomaticus major, while participants performed a gender classification task on faces expressing various emotional states...
November 17, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/29149992/a-separable-surface-enhanced-raman-scattering-substrate-modified-with-mil-101-for-detection-of-overlapping-and-invisible-compounds-after-thin-layer-chromatography-development
#3
Bin Bin Zhang, Yi Shi, Hui Chen, Qing Xia Zhu, Feng Lu, Ying Wei Li
By coupling surface-enhanced Raman spectroscopy (SERS) with thin-layer chromatography (TLC), a powerful method for detecting complex samples was successfully developed. However, in the TLC-SERS method, metal nanoparticles serving as the SERS-active substrate are likely to disturb the detection of target compounds, particularly in overlapping compounds after TLC development. In addition, the SERS detection of compounds that are invisible under both visible light and UV254/365 after TLC development is still a significant challenge...
January 2, 2018: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29149508/implementing-quantum-search-algorithm-with-metamaterials
#4
Weixuan Zhang, Kaiyang Cheng, Chao Wu, Yi Wang, Hongqiang Li, Xiangdong Zhang
Metamaterials, artificially structured electromagnetic (EM) materials, have enabled the realization of many unconventional EM properties not found in nature, such as negative refractive index, magnetic response, invisibility cloaking, and so on. Based on these man-made materials with novel EM properties, various devices are designed and realized. However, quantum analog devices based on metamaterials have not been achieved so far. Here, metamaterials are designed and printed to perform quantum search algorithm...
November 17, 2017: Advanced Materials
https://www.readbyqxmd.com/read/29149239/label-free-in-vivo-imaging-of-corneal-lymphatic-vessels-using-microscopic-optical-coherence-tomography
#5
Jens Horstmann, Hinnerk Schulz-Hildebrandt, Felix Bock, Sebastian Siebelmann, Eva Lankenau, Gereon Hüttmann, Philipp Steven, Claus Cursiefen
Purpose: Corneal neovascularization, in particular lymphangiogenesis, is a limiting factor in corneal transplant survival. Novel treatment approaches focus on (selective) inhibition and regression of lymphatic vessels. Imaging clinically invisible corneal lymphatic vessels is a prerequisite for these strategies. Using a murine model, this study investigates whether corneal lymphatic vessels can be imaged using microscopic optical coherence tomography (mOCT). Methods: Corneal neovascularization was induced by intrastromal placement of 11...
November 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29139336/home-health-aides-perceptions-of-quality-care-goals-challenges-and-implications-for-a-rapidly-changing-industry
#6
Emily Franzosa, Emma K Tsui, Sherry Baron
Home care payment models, quality measures, and care plans are based on physical tasks workers perform, ignoring relational care that supports clients' cognitive, emotional, and social well-being. As states seek to rein in costs and improve the efficiency and quality of care, they will need to consider how to measure and support relational care. In four focus groups ( n = 27) of unionized, agency-based New York City home health aides, workers reported aide-client relationships were a cornerstone of high-quality care, and building them required communication, respect, and going the extra mile...
January 1, 2017: New Solutions: a Journal of Environmental and Occupational Health Policy: NS
https://www.readbyqxmd.com/read/29135796/voices-of-the-filipino-community-describing-the-importance-of-family-in-understanding-adolescent-behavioral-health-needs
#7
Joyce R Javier, Kristina Galura, Frank Anthony P Aliganga, Jocelyn Supan, Lawrence A Palinkas
Filipinos are a large, yet invisible, minority at high risk for adolescent behavioral health problems. Limited research describes the family as offering a source of positive support for some Filipino youths and yet for some it is also a source of stress and isolation, leading to struggles with adolescent depression and suicidal behavior. This article describes a qualitative study that investigates the role of family when understanding behavioral health needs among Filipino adolescents. Findings highlight the importance of addressing family cohesion when designing interventions aimed at improving the well-being of Filipino youth...
January 2018: Family & Community Health
https://www.readbyqxmd.com/read/29135605/novel-method-to-detect-corneal-lymphatic-vessels-in-vivo-by-intrastromal-injection-of-fluorescein
#8
Viet Nhat Hung Le, Yanhong Hou, Jens Horstmann, Felix Bock, Claus Cursiefen
PURPOSE: Corneal lymphatic vessels are clinically invisible because of their thin walls and clear lymph fluid. There is no easy and established method for in vivo imaging of corneal lymphatic vessels so far. In this study, we present a novel approach to visualize corneal lymphatic vessels in vivo by injecting intrastromal fluorescein sodium. METHODS: Six- to eight-week-old female BALB/c mice were used in the mouse model of suture-induced corneal neovascularization...
November 9, 2017: Cornea
https://www.readbyqxmd.com/read/29135342/invisible-parasites-and-their-implications-for-coexisting-water-fleas
#9
Tara Elizabeth Stewart, Mark Torchin, Carla Cáceres
The top-down effects of consumers, like predators, are known to affect abundances, size structure, and species composition in aquatic ecosystems. Parasites are also important in shaping the ecology of free-living species, however, their effects are often overlooked because parasites can be difficult to detect. Parasites can be particularly challenging to observe in zooplankton hosts because of their small size and ephemeral infection periods. To overcome these challenges, we used a quarantine approach combined with high magnification microscopy to increase detection of parasites of the tropical Cladoceran, Ceriodaphnia cornuta, in Lake Gatun, Panamá...
November 14, 2017: Journal of Parasitology
https://www.readbyqxmd.com/read/29133469/an-invisible-ubiquitin-conformation-is-required-for-efficient-phosphorylation-by-pink1
#10
Christina Gladkova, Alexander F Schubert, Jane L Wagstaff, Jonathan N Pruneda, Stefan M V Freund, David Komander
The Ser/Thr protein kinase PINK1 phosphorylates the well-folded, globular protein ubiquitin (Ub) at a relatively protected site, Ser65. We previously showed that Ser65 phosphorylation results in a conformational change in which Ub adopts a dynamic equilibrium between the known, common Ub conformation and a distinct, second conformation wherein the last β-strand is retracted to extend the Ser65 loop and shorten the C-terminal tail. We show using chemical exchange saturation transfer (CEST) nuclear magnetic resonance experiments that a similar, C-terminally retracted (Ub-CR) conformation also exists at low population in wild-type Ub...
November 13, 2017: EMBO Journal
https://www.readbyqxmd.com/read/29124692/ultraviolet-radiations-skin-defense-damage-mechanism
#11
Dheeraj Mohania, Shikha Chandel, Parveen Kumar, Vivek Verma, Kumar Digvijay, Deepika Tripathi, Khushboo Choudhury, Sandeep Kumar Mitten, Dilip Shah
UV-radiations are the invisible part of light spectra having a wavelength between visible rays and X-rays. Based on wavelength, UV rays are subdivided into UV-A (320-400 nm), UV-B (280-320 nm) and UV-C (200-280 nm). Ultraviolet rays can have both harmful and beneficial effects. UV-C has the property of ionization thus acting as a strong mutagen, which can cause immune-mediated disease and cancer in adverse cases. Numbers of genetic factors have been identified in human involved in inducing skin cancer from UV-radiations...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29121788/fluorescence-image-guided-neurosurgery
#12
Sadao Kaneko, Muftah S Eljamel
Surgery plays an important role in the management of high-grade gliomas (HGG) and imparts significant tumor-free and overall survival advantages. However HGG margins are often invisible, making their gross total resection (GTR) a difficult task. Hence intraoperative technology such as intraoperative fluorescence was a revolutionary discovery. A critical literature review revealed fluorescence improved the GTR of HGG from 36% using standard surgery to 74.5 and 84.4% using aminolevulinic acid (ALA) or fluorescein (FLCN), respectively...
November 2017: Future Oncology
https://www.readbyqxmd.com/read/29121778/intraoperative-image-guided-surgery-in-neuro-oncology-with-specific-focus-on-high-grade-gliomas
#13
Syed O Mahboob, Muftah Eljamel
Surgery is paramount in glioma management and extent of resection is an independent significant prognostic factor. However, these tumors are often invisible intraoperatively. Hence imaging plays an important role in surgical guidance. A critical literature review, using MEDLINE/PubMed service was carried out. It demonstrated a gross total resection (GTR) with neuronavigation (NNS) of 31-36%, adding 5-aminolevulinic acid or fluorescein fluorescence, or intraoperative ultrasound or MRI improved GTR to 69.1, 84...
November 2017: Future Oncology
https://www.readbyqxmd.com/read/29117511/the-role-of-mucus-as-an-invisible-cloak-to-transepithelial-drug-delivery-by-nanoparticles
#14
María García-Díaz, Ditlev Birch, Feng Wan, Hanne Mørck Nielsen
Mucosal administration of drugs and drug delivery systems has gained increasing interest. However, nanoparticles intended to protect and deliver drugs to epithelial surfaces require transport through the surface-lining mucus. Translation from bench to bedside is particularly challenging for mucosal administration since a variety of parameters will influence the specific barrier properties of the mucus including the luminal fluids, the microbiota, the mucus composition and clearance rate, and the condition of the underlying epithelia...
November 5, 2017: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/29116088/statistical-parity-time-symmetric-lasing-in-an-optical-fibre-network
#15
Ali K Jahromi, Absar U Hassan, Demetrios N Christodoulides, Ayman F Abouraddy
Parity-time (PT)-symmetry in optics is a condition whereby the real and imaginary parts of the refractive index across a photonic structure are deliberately balanced. This balance can lead to interesting optical phenomena, such as unidirectional invisibility, loss-induced lasing, single-mode lasing from multimode resonators, and non-reciprocal effects in conjunction with nonlinearities. Because PT-symmetry has been thought of as fragile, experimental realisations to date have been usually restricted to on-chip micro-devices...
November 7, 2017: Nature Communications
https://www.readbyqxmd.com/read/29100216/commentary-on-still-invisible-after-all-these-years
#16
Steven Lippmann
No abstract text is available yet for this article.
November 2017: Southern Medical Journal
https://www.readbyqxmd.com/read/29100215/still-invisible-after-all-these-years
#17
Farrin A Manian
No abstract text is available yet for this article.
November 2017: Southern Medical Journal
https://www.readbyqxmd.com/read/29099625/prevalence-of-depression-and-anxiety-among-bisexual-people-compared-to-gay-lesbian-and-heterosexual-individuals-a-systematic-review-and-meta-analysis
#18
Lori E Ross, Travis Salway, Lesley A Tarasoff, Jenna M MacKay, Blake W Hawkins, Charles P Fehr
Over the past decade, evidence has accumulated to suggest that bisexual people experience higher rates of poor mental health outcomes compared to both heterosexual and gay/lesbian individuals. However, no previous meta-analyses have been conducted to establish the magnitude of these disparities. To address this research gap, we conducted a systematic review and meta-analysis of studies that reported bisexual-specific data on standardized measures of depression or anxiety. Of the 1,074 full-text articles reviewed, 1,023 were ineligible, predominantly because they did not report separate data for bisexual people (n = 562 studies)...
November 3, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/29097234/patterns-of-bowel-invisible-microscopic-endometriosis-reveal-the-goal-of-surgery-removal-of-visual-lesions-only
#19
Alexandra Badescu, Horace Roman, Iulia Barsan, Valentin Soldea, Serban Nastasia, Moutaz Aziz, Lucian Puscasiu, Simona Stolnicu
STUDY OBJECTIVE: To document the presence of bowel invisible microscopic endometriosis implants and their relationship with deep endometriosis macronodule infiltrating the bowel. DESIGN: A series of consecutive patients with deep endometriosis infiltrating the rectum and/or sigmoid colon. DESIGN CLASSIFICATION: Canadian Task Force classification II-2. SETTINGS: University referral center. PATIENTS: Ten patients managed by colorectal resection...
October 30, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29094064/vibrational-detection-of-odorant-functional-groups-by-drosophila-melanogaster
#20
Klio Maniati, Katherine-Joanne Haralambous, Luca Turin, Efthimios M C Skoulakis
A remarkable feature of olfaction, and perhaps the hardest one to explain by shape-based molecular recognition, is the ability to detect the presence of functional groups in odorants, irrespective of molecular context. We previously showed that Drosophila trained to avoid deuterated odorants could respond to a molecule bearing a nitrile group, which shares the vibrational stretch frequency with the CD bond. Here, we reproduce and extend this finding by showing analogous olfactory responses of Drosophila to the chemically vastly different functional groups, thiols and boranes, that nevertheless possess a common vibration at 2600 cm(-1)...
September 2017: ENeuro
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