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https://www.readbyqxmd.com/read/29768259/precise-intradermal-injection-of-nanofat-derived-stromal-cells-combined-with-platelet-rich-fibrin-improves-the-efficacy-of-facial-skin-rejuvenation
#1
Zhi-Jie Liang, Xiang Lu, De-Quan Li, Yi-Dan Liang, Dan-Dan Zhu, Fang-Xiao Wu, Xiao-Lin Yi, Ning He, Yan-Qing Huang, Chao Tang, Hong-Mian Li
BACKGROUND/AIMS: The rejuvenation properties of nanofat grafting have been described in recent years. However, it is not clear whether the clinical efficacy of the procedure is attributable to stem cells or linked to other components of adipose tissue. In this study we isolated nanofat-derived stem cells (NFSCs) to observe their biological characteristics and evaluate the efficacy of precise intradermal injection of nanofat combined with platelet-rich fibrin (PRF) in patients undergoing facial rejuvenation treatment...
May 11, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29766249/imaging-of-temporomandibular-joint-abnormalities-in-juvenile-idiopathic-arthritis-with-a-focus-on-developing-a-magnetic-resonance-imaging-protocol
#2
REVIEW
Elka Miller, Emilio J Inarejos Clemente, Nikolay Tzaribachev, Saurabh Guleria, Mirkamal Tolend, Arthur B Meyers, Thekla von Kalle, Jennifer Stimec, Bernd Koos, Simone Appenzeller, Linda Z Arvidsson, Eva Kirkhus, Andrea S Doria, Christian J Kellenberger, Tore A Larheim
Inflammation and damage in the temporomandibular joint (TMJ) often develop without clinical symptoms but can lead to severe facial growth abnormalities and impaired health-related quality of life, making early diagnosis of TMJ changes crucial to identify. Inflammatory and osteochondral changes detectable through magnetic resonance imaging (MRI) occur in TMJs of approximately 40% of children with juvenile idiopathic arthritis (JIA), and no other imaging modality or physical method of examination can reliably detect these changes...
June 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29762453/microvascular-replantation-following-facial-dog-bites-in-children-systematic-review-and-management-algorithm
#3
Amanda J Williams, Jeremy M Powers, Jennifer L Rhodes, Andrea L Pozez
BACKGROUND: Pediatric dog bite injuries account for 1% of emergency department visits per year and represent an underrecognized and underreported public health problem. Reconstructive surgery is frequently utilized, and in the most extreme injuries, microvascular replantation may be considered. We sought to systematically review the available literature on microvascular replantation after facial dog bite injuries in children, with particular attention to perioperative morbidity and long-term follow-up...
May 14, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29761887/telomere-length-and-genetic-variations-affecting-telomere-length-as-biomarkers-for-facial-regeneration-with-platelet-rich-fibrin-based-on-the-low-speed-centrifugation-concept
#4
Cleopatra Nacopoulos, Kalliopi Gkouskou, Dimitrios Karypidis, Ioannis Vlastos, Anna-Maria Vesala, Joseph Choukroun, Richard J Miron, Emmanuel Prokopakis
BACKGROUND: Platelet-Rich Fibrin (PRF), a fibrin matrix produced by single blood centrifugation that contains leukocytes, platelets, and growth factors, is increasingly being utilized for facial regeneration purposes. However, our understanding of the involved pathophysiological mechanisms affecting regeneration is limited and current protocols require better optimization. Biomarkers that are related to skin aging such as telomere length (TL) have been proposed as a mean to analyze patients' stratification...
May 15, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29755898/an-unusual-presentation-of-kikuchi-fujimoto-disease-with-recurrent-subdural-effusion
#5
Sara Shahid, Syed H Alam, Indira Hadley
A 24-year-old man complained of a right temporal headache for four weeks. The patient denied any trauma or previous anticoagulation use. He also reported tender right facial swelling. His physical exam was unrevealing except for right cranial nerve (CN) VI palsy, right parotid enlargement, and cervical adenopathy. Laboratory findings were significant for mild leukopenia at 3300 cells/uL. The computed tomography (CT) scan obtained showed a chronic left subdural effusion with a 4 mm midline shift and confirmed right parotid enlargement and cervical lymphadenopathy...
March 10, 2018: Curēus
https://www.readbyqxmd.com/read/29751329/determination-of-metals-and-pharmaceutical-compounds-released-in-hospital-wastewater-from-toluca-mexico-and-evaluation-of-their-toxic-impact
#6
Itzayana Pérez-Alvarez, Hariz Islas-Flores, Leobardo Manuel Gómez-Oliván, Damià Barceló, Miren López De Alda, Sandra Pérez Solsona, Livier Sánchez-Aceves, Nely SanJuan-Reyes, Marcela Galar-Martínez
Due to the activities inherent to medical care units, the hospital effluent released contains diverse contaminants such as tensoactives, disinfectants, metals, pharmaceutical products and chemical reagents, which are potentially toxic to the environment since they receive no treatment or are not effectively removed by such treatment before entering the drain. They are incorporated into municipal wastewater, eventually entering water bodies where they can have harmful effects on organisms and can result in ecological damage...
May 8, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29724987/platelet-rich-plasma-prp-rinses-for-the-treatment-of-non-responding-oral-lichen-planus-a-case-report
#7
Elisabetta Merigo, Aldo Oppici, Anna Parlatore, Luigi Cella, Fabio Clini, Matteo Fontana, Carlo Fornaini
Platelet-rich plasma (PRP) has been proposed for different applications in the medical field and in maxillofacial surgery thanks to its many growth factors, such as epidermal growth factor (EGF), fibroblast growth factor (FGF), and keratinocyte growth factor (KGF). Oral lichen planus (OLP) is a disease that affects the oral mucosa in a chronic way. This disease frequently worsens the quality of life of patients, particularly when clinical manifestations are of the erythematous or erosive/ulcerative type. The properties of PRP that are supported by scientific literature in both oral medicine and other medical fields have suggested the introduction of PRP in clinical practice for the medical treatment of different soft tissues diseases, such as when OLP patients do not respond to conventional therapies, or when conventional treatments have some contraindications or side effects...
February 6, 2018: Biomedicines
https://www.readbyqxmd.com/read/29722897/mucopolysaccharidosis-vi-and-effects-on-growth-of-the-apical-bases-a-case-report
#8
Moema Ferreira Dos Reis, Lucas Rodrigues Pinheiro, Maria das Graças Rodrigues Pinheiro, Haroldo Amorim de Almeida, Patrícia do Socorro Queiroz Feio, Sâmia Cordovil de Almeida, Isabel Cristina Neves de Souza, Roberto Giugliani, Ida Vanessa Doederlein Schwartz, Rosely Maria Dos Santos Cavaleiro, João de Jesus Viana Pinheiro, Luiz Carlos Santana da Silva
OBJECTIVE: Mucopolysaccharidosis (MPS) VI is a rare disorder caused by an autosomal recessive mutation in the short arm of chromosome 5 (5q12-13) leading to an N-acetylgalactosamine-sulfatase lysosomal enzyme deficiency and numerous systemic clinical changes. The oral and maxillofacial complex may exhibit tooth eruption anomalies, macroglossia, gingival hypertrophy, mouth breathing, increased lower facial height, open bite, retrognathia, and progressive TMJ arthrosis. This report describes craniofacial growth changes in two MPS VI patients, sisters and daughters of outbred parents, who were longitudinally monitored from 11 to 15 years of age...
May 3, 2018: Special Care in Dentistry
https://www.readbyqxmd.com/read/29721915/clinical-biochemical-and-molecular-overview-of-transaldolase-deficiency-and-evaluation-of-the-endocrine-function-update-of-34-patients
#9
M Williams, V Valayannopoulos, R Altassan, W K Chung, A C Heijboer, W T Keng, R Lapatto, P McClean, M F Mulder, A Tylki-Szymańska, M J E Walenkamp, M Alfadhel, H Alakeel, G S Salomons, W Eyaid, M M C Wamelink
BACKGROUND: Transaldolase deficiency (TALDO-D) is a rare autosomal recessive inborn error of the pentose phosphate pathway. Since its first description in 2001, several case reports have been published, but there has been no comprehensive overview of phenotype, genotype, and phenotype-genotype correlation. METHODS: We performed a retrospective questionnaire and literature study of clinical, biochemical, and molecular data of 34 patients from 25 families with proven TALDO-D...
May 2, 2018: Journal of Inherited Metabolic Disease
https://www.readbyqxmd.com/read/29714701/delayed-tooth-reimplantation-with-4-year-follow-up-the-management-of-ankylosis-during-facial-growth
#10
Franciny Querobim Ionta, Priscilla Santana Pinto Gonçalves, Heitor Marques Honório, Gabriela Cristina de Oliveira, Catarina Ribeiro Barros de Alencar, Natália Mello Santos, Thais Marchini de Oliveira, Daniela Rios
This case report describes the consequences of delayed (24 hours) reimplantation of an avulsed maxillary central incisor, findings over a 4-year follow-up period, and the management of ankylosis during facial growth. After a traumatic event, a 10-year-old boy was taken to a hospital emergency department due to injuries to his face, including avulsion of the maxillary left central incisor. Despite the short amount of time before arriving at the hospital (10 minutes) and use of the correct storage medium (milk), the tooth was not reimplanted, and the parents did not receive instructions to seek dental treatment...
May 2018: General Dentistry
https://www.readbyqxmd.com/read/29708396/evaluation-of-characteristics-of-the-craniofacial-complex-and-dental-maturity-in-girls-with-central-precocious-puberty
#11
Hee-Kyung Lee, Sung-Hwan Choi, Dong Fan, Kyung-Mi Jang, Min-Seon Kim, Chung-Ju Hwang
OBJECTIVES: To identify unique characteristics of the craniofacial complex and dental maturity in girls with central precocious puberty (CPP). MATERIALS AND METHODS: This study included 34 Korean girls with idiopathic CPP (mean age, 8.6 ± .5 years) and 28 normal healthy girls of the same chronological age. An initial evaluation of the growth pattern of the craniofacial complex and dental maturity was conducted by analyzing lateral cephalometric and panoramic radiographs...
April 30, 2018: Angle Orthodontist
https://www.readbyqxmd.com/read/29706218/prediction-of-the-occurrence-and-severity-of-mandibular-incisor-crowding-in-the-early-mixed-dentition-using-craniofacial-parameters
#12
Ahmadreza Sardarian, Faezeh Ghaderi
INTRODUCTION: With the recent interest in esthetics at an early age, prediction of mandibular incisor crowding is of significant importance. Since dental arch development is related to craniofacial growth, we conducted a cohort study to find a regression model for mandibular incisor crowding based on various craniofacial parameters in children. METHODS: A total of 250 children, all in the early mixed dentition, were selected randomly by cluster sampling from primary schools...
May 2018: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/29706215/longitudinal-eruptive-and-posteruptive-tooth-movements-studied-on-oblique-and-lateral-cephalograms-with-implants
#13
Xiaoyun Zhang, Sheldon Baumrind, Gui Chen, Huizhong Chen, Yi Liang, Tianmin Xu
INTRODUCTION: The purpose of this study was to investigate the eruptive and posteruptive tooth displacements of untreated growing subjects longitudinally and the potential connections between posteruptive displacement of the maxillary and mandibular first molars and skeletal facial growth. METHODS: The sample comprised 11 series of right 45° oblique cephalograms and lateral cephalograms of untreated children with metallic implants of the Björk type obtained from the archives of a growth study...
May 2018: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/29704308/a-sibling-pair-with-cardiofaciocutaneous-syndrome-cfc-secondary-to-braf-mutation-with-unaffected-parents-the-first-cases-of-gonadal-mosaicism-in-cfc
#14
Sarah Geoghegan, Graham King, Jennifer Henchliffe, Simon C Ramsden, Raymond J Barry, Andrew J Green, Susan M O'Connell
Cardiofaciocutaneous (CFC) syndrome is a RASopathy characterized by intellectual disability, congenital heart defects, a characteristic facial appearance, gastro-intestinal complications, ectodermal abnormalities and growth failure. The RASopathies result from germline mutations in the Ras/Mitogen-activated-protein-kinase (MAPK) pathway. CFC is associated with mutations in BRAF, KRAS, MEK1 and MEK2. CFC has been considered a "sporadic" disorder, with minimal recurrence risk to siblings. In recent years, vertical transmission of CFC has been seen in mutations involving the MEK2 and KRAS genes, but has not previously been reported with BRAF mutations...
April 28, 2018: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29702739/midfacial-growth-patterns-in-males-from-newborn-to-5-years-old-based-on-computed-tomography
#15
Andrej Evteev, Anatoliy Anikin, Leonid Satanin
OBJECTIVES: Growth patterns of the human facial skeleton have been of great interest and importance for biological anthropologists, forensic scientists, craniofacial surgeons, and orthopedists. Nevertheless, growth trends of the facial skeleton in infancy and early childhood are still poorly known and clinical CT data have been insufficiently used for studying craniofacial ontogeny. The purpose of this study was to provide a comprehensive quantitative description of human midfacial ontogeny in infancy and early childhood, and to contribute to debates regarding the role of modularity vs...
April 27, 2018: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/29701176/consequences-of-delay-in-screening-monitoring-and-treatment-of-angiomyolipoma-and-tuberous-sclerosis-a-case-report
#16
Tanjala T Gipson
BACKGROUND: Tuberous sclerosis complex (TSC) is a multisystem disorder that results in tumor growth in various organs. TSC can affect the kidneys in the form of renal angiomyolipomas and cysts that can lead to chronic kidney disease. CASE PRESENTATION: A 38-year-old woman was referred to Kennedy Krieger Institute for comprehensive TSC management. Before referral, the patient had gone most of her life without a definite diagnosis of TSC despite visually-prominent signs such as forehead plaques, facial angiofibromas, and ungual fibromas...
April 27, 2018: Clinical Nephrology
https://www.readbyqxmd.com/read/29697963/cluster-mediated-nucleation-and-growth-of-j-and-h-type-polymorphs-of-difluoroboron-avobenzone-for-organic-microribbon-lasers
#17
Qing Liao, Xin Guo Wang, Shaokai Lv, Zhenzhen Xu, Yi Zhang, Hongbing Fu
Controlled fabrication of organic polymorphisms with well-defined dimensions and tunable luminescent properties plays an important role in developing optoelectronic devices, sensors and bio-labeling agents, but remains a challenge due to the weak intermolecular interactions among organic molecules. Herein, we developed a two-step solution self-assemble method for controlled preparation of blue-emissive or green-emissive micro-ribbons (MRs) of difluoroboron avobenzone (BF2AVB) by adjusting the cluster-mediated nucleation and subsequent one-dimensional growth processes...
April 26, 2018: ACS Nano
https://www.readbyqxmd.com/read/29696806/association-of-17q24-2-q24-3-deletions-with-recognizable-phenotype-and-short-telomeres
#18
Miroslava Hancarova, Marcela Malikova, Michaela Kotrova, Jana Drabova, Marie Trkova, Zdenek Sedlacek
Microdeletions of 17q24.2-q24.3 have been described in several patients with developmental and speech delay, growth retardation, and other features. The relatively large size and limited overlap of the deletions complicate the genotype-phenotype correlation. We identified a girl with intellectual disability, growth retardation, dysmorphic features, and a de novo 2.8 Mb long deletion of 17q24.2-q24.3. Her phenotype was strikingly similar to one previously described boy with Dubowitz syndrome (MIM 223370) and a de novo 3...
April 25, 2018: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29694413/proline-oxidase-controls-proline-glutamate-and-glutamine-cellular-concentrations-in-a-u87-glioblastoma-cell-line
#19
Pamela Cappelletti, Elena Tallarita, Valentina Rabattoni, Paola Campomenosi, Silvia Sacchi, Loredano Pollegioni
L-Proline is a multifunctional amino acid that plays an essential role in primary metabolism and physiological functions. Proline is oxidized to glutamate in the mitochondria and the FAD-containing enzyme proline oxidase (PO) catalyzes the first step in L-proline degradation pathway. Alterations in proline metabolism have been described in various human diseases, such as hyperprolinemia type I, velo-cardio-facial syndrome/Di George syndrome, schizophrenia and cancer. In particular, the mutation giving rise to the substitution Leu441Pro was identified in patients suffering of schizophrenia and hyperprolinemia type I...
2018: PloS One
https://www.readbyqxmd.com/read/29690969/molecular-pathogenesis-of-chewable-tobacco
#20
Saeeda Baig, Zile Rubab, Wasfa Farooq
In Pakistan, extensive use of several precarious chewable tobacco formulations has made oral cancer the second leading malignancy. Selection of literature was done by a survey of studies published from 1990 to 2017 mainly, from PUBMED and few from other search engines, on naswar, gutka, areca nut and betel quid, which included published reviews, original articles and other data sources on chewable tobacco, its epidemiology, pathological implications, and psychological effects. These studies have revealed that the chemicals in these formulations bind and mutate DNA of oral mucosa through down regulating cellular repair pathways and upregulating genetic networks associated with pathogenesis...
May 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
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