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cardiac arrythmia

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https://www.readbyqxmd.com/read/27592289/echocardiography-as-a-guide-for-fluid-management
#1
REVIEW
John H Boyd, Demetrios Sirounis, Julien Maizel, Michel Slama
BACKGROUND: In critically ill patients at risk for organ failure, the administration of intravenous fluids has equal chances of resulting in benefit or harm. While the intent of intravenous fluid is to increase cardiac output and oxygen delivery, unwelcome results in those patients who do not increase their cardiac output are tissue edema, hypoxemia, and excess mortality. Here we briefly review bedside methods to assess fluid responsiveness, focusing upon the strengths and pitfalls of echocardiography in spontaneously breathing mechanically ventilated patients as a means to guide fluid management...
September 4, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/26894157/bilateral-carpal-spasm-under-spinal-anaesthesia-during-abdominal-hysterectomy-a-case-report
#2
Abhilasha Thanvi, Udita Naithani, Sneha Arun Betkekar, Devendra Verma, Basant Kumar Dindor
Acute hypocalcaemia is a medical emergency that can have catastrophic implications like tetany, seizures, cardiac arrythmias or laryngospasm if left untreated. We are presenting a case of a 30-year-old female patient undergoing total abdominal hysterectomy with bilateral salpingoopherectomy under spinal anaesthesia. She developed unexpected bilateral carpal spasm intraoperatively which was promptly diagnosed and successfully managed with intravenous calcium administration. We conclude that the anaesthetist should be aware of the clinical presentation of acute hypocalcaemia, its causes and emergency management in the perioperative period to prevent any adverse outcomes...
January 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26609375/straightforward-and-robust-qrs-detection-algorithm-for-wearable-cardiac-monitor
#3
M Sabarimalai Manikandan, Barathram Ramkumar
This Letter presents a fairly straightforward and robust QRS detector for wearable cardiac monitoring applications. The first stage of the QRS detector contains a powerful ℓ1-sparsity filter with overcomplete hybrid dictionaries for emphasising the QRS complexes and suppressing the baseline drifts, powerline interference and large P/T waves. The second stage is a simple peak-finding logic based on the Gaussian derivative filter for automatically finding locations of R-peaks in the ECG signal. Experiments on the standard MIT-BIH arrythmia database show that the method achieves an average sensitivity of 99...
January 2014: Healthcare Technology Letters
https://www.readbyqxmd.com/read/26520033/gastrobronchial-fistula-following-minimally-invasive-esophagectomy-for-esophageal-cancer-in-a-patient-with-myotonic-dystrophy-case-report
#4
Silje Hugin, Egil Johnson, Hans-Olaf Johannessen, Bjørn Hofstad, Kjell Olafsen, Harald Mellem
INTRODUCTION: Myotonic dystrophies are inherited multisystemic diseases characterized by musculopathy, cardiac arrythmias and cognitive disorders. These patients are at increased risk for fatal post-surgical complications from pulmonary hypoventilation. We present a case with myotonic dystrophy and esophageal cancer who had a minimally invasive esophagectomy complicated with gastrobronchial fistulisation. PRESENTATION OF CASE: A 44-year-old male with myotonic dystrophy type 1 and esophageal cancer had a minimally invasive esophagectomy performed instead of open surgery in order to reduce the risk for pulmonary complications...
2015: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/26317911/direct-exposure-to-ethanol-disrupts-junctional-cell-cell-contact-and-hippo-yap-signaling-in-hl-1-murine-atrial-cardiomyocytes
#5
Kanako Noritake, Toshihiko Aki, Takeshi Funakoshi, Kana Unuma, Koichi Uemura
Direct exposure of cardiomyocytes to ethanol causes cardiac damage such as cardiac arrythmias and apoptotic cell death. Cardiomyocytes are connected to each other through intercalated disks (ID), which are composed of a gap junction (GJ), adherens junction, and desmosome. Changes in the content as well as the subcellular localization of connexin43 (Cx43), the main component of the cardiac GJ, are reportedly involved in cardiac arrythmias and subsequent damage. Recently, the hippo-YAP signaling pathway, which links cellular physical status to cell proliferation, differentiation, and apoptosis, has been implicated in cardiac homeostasis under physiological as well as pathological conditions...
2015: PloS One
https://www.readbyqxmd.com/read/25925484/is-foxglove-effective-in-heart-failure
#6
REVIEW
Parminder S Chaggar, Steven M Shaw, Simon G Williams
BACKGROUND: Digoxin is the oldest known treatment for heart failure (HF) and has been demonstrated to reduce admissions for worsening heart failure in a large randomized trial recruiting patients in sinus rhythm with heart failure and ejection fraction <45%. This study forms the basis for current international guidelines recommending that digoxin should be considered in patients with symptomatic HF despite optimal doses of angiotensin-converting enzyme inhibitors/angiotensin receptor blockers, β-blockers, and mineralocorticoid receptor antagonists in addition to device therapy, if indicated...
August 2015: Cardiovascular Therapeutics
https://www.readbyqxmd.com/read/25767351/spontaneous-chemoport-fracture-and-cardiac-migration
#7
Mishal Shah, Sanjeev Patni, Rajeev Bagarahatta
Central venous access devices are routinely used in oncology for delivering chemotherapy of which implantable chemoports are the most common. Spontaneous breakage and migration of the catheters is a very rare but known complication of the procedure. Patients will usually present with cardiac manifestations in form of chest pain or arrythmias. Herein we report a case of spontaneous breakage and cardiac migration in which the patient was asymptomatic. Patient was successfully managed by an interventional cardiologist...
December 2014: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/25655574/proton-pump-inhibitor-use-is-not-associated-with-cardiac-arrhythmia-in-critically-ill-patients
#8
COMPARATIVE STUDY
Kenneth P Chen, Joon Lee, Roger G Mark, Mengling Feng, Leo A Celi, Brian E Malley, John Danziger
Hypomagnesemia can lead to cardiac arrythmias. Recently, observational data have linked chronic proton pump inhibitor (PPI) exposure to hypomagnesemia. Whether PPI exposure increases the risk for arrhythmias has not been well studied. Using a large, single-center inception cohort of critically ill patients, we examined whether PPI exposure was associated with admission electrocardiogram readings of a cardiac arrhythmia in more than 8000 patients. There were 25.4% PPI users, whereas 6% were taking a histamine 2 antagonist...
July 2015: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/25567850/heart-disease-is-common-in-humans-and-chimpanzees-but-is-caused-by-different-pathological-processes
#9
Nissi Varki, Dan Anderson, James G Herndon, Tho Pham, Christopher J Gregg, Monica Cheriyan, James Murphy, Elizabeth Strobert, Jo Fritz, James G Else, Ajit Varki
Heart disease is common in both humans and chimpanzees, manifesting typically as sudden cardiac arrest or progressive heart failure. Surprisingly, although chimpanzees are our closest evolutionary relatives, the major cause of heart disease is different in the two species. Histopathology data of affected chimpanzee hearts from two primate centers, and analysis of literature indicate that sudden death in chimpanzees (and in gorillas and orangutans) is commonly associated with diffuse interstitial myocardial fibrosis of unknown cause...
February 2009: Evolutionary Applications
https://www.readbyqxmd.com/read/25350413/-a-fatal-overdose-of-venlafaxine
#10
Julie Steen Pedersen, Lars Kristian Munck
An 18-year-old woman ingested 22 g of venlafaxine with suicidal attempt. At admittance two hours after ingestion she had serotonine syndrome, repeated seizures and hypotension. After eight hours malignant arrythmias culminated in cardiac arrest, which was successfully resuscitated. Progressive liver and cardiac failure lead to fatal outcome after 48 hours. It is discussed whether early lipid infusion should be given in case of ingestion of high doses of venlafaxine, before myoclonia, seizures, hypotension, rhabdomyolysis and liver failure developed, since these can only be treated symptomatically...
February 24, 2014: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/25219225/-an-improved-wavelet-threshold-algorithm-for-ecg-denoising
#11
Xiuling Liu, Lei Qiao, Jianli Yang, Bin Dong, Hongrui Wang
Due to the characteristics and environmental factors, electrocardiogram (ECG) signals are usually interfered by noises in the course of signal acquisition, so it is crucial for ECG intelligent analysis to eliminate noises in ECG signals. On the basis of wavelet transform, threshold parameters were improved and a more appropriate threshold expression was proposed. The discrete wavelet coefficients were processed using the improved threshold parameters, the accurate wavelet coefficients without noises were gained through inverse discrete wavelet transform, and then more original signal coefficients could be preserved...
June 2014: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
https://www.readbyqxmd.com/read/25192922/impact-of-atrial-fibrillation-on-the-cardiovascular-system-through-a-lumped-parameter-approach
#12
Stefania Scarsoglio, Andrea Guala, Carlo Camporeale, Luca Ridolfi
Atrial fibrillation (AF) is the most common arrhythmia affecting millions of people in the Western countries and, due to the widespread impact on the population and its medical relevance, is largely investigated in both clinical and bioengineering sciences. However, some important feedback mechanisms are still not clearly established. The present study aims at understanding the global response of the cardiovascular system during paroxysmal AF through a lumped-parameter approach, which is here performed paying particular attention to the stochastic modeling of the irregular heartbeats and the reduced contractility of the heart...
November 2014: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/24779221/-influenza-infection-in-intensive-cardiac-care-unit-patients
#13
REVIEW
Katrzyna Ciuraszkiewicz, Janusz Sielski, Agnieszka Janion-Sadowska, Agnieszka Stern, Joanna Zychowicz, Karol Kaziród-Wolski, Marian Paluchowski
Infection with influenza type A virus may cause serious cardiovascular complications, such as myocarditis, heart failure, acute myocardial infarction. Also infection with influenza type AH1N1 may contribute to aggravation of cardiac disorders, i.e. acute coronary syndrome, heart failure, cardiogenic shock, severe ventricular arrythmias. One of the most fatal complication of influenza is pneumonia leading to acute respiratory insufficiency requiring artifitial ventilation. Symptoms of respiratory tract infections durnig influenza epidemy should always be treated with a high index of suspicion...
March 2014: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/24692794/preconditionin-effects-of-dexmedetomidine-on-myocardial-ischemia-reperfusion-injury-in-rats
#14
Hasan Kocoglu, Kazim Karaaslan, Ersoz Gonca, Omer Bozdogan, Nebahat Gulcu
BACKGROUND: Preconditioning might protect the myocardium against ischemia/ reperfusion injury by reducing infarct size and preventing arrhythmias. Dexmedetomidine (DEX) is a highly selective α2-agonist used for sedoanalgesia in daily anesthetic practice. The cardioprotective effects of DEX on infarct size and on the incidence of arrhythmias observed after regional ischemia/reperfusion injury in vivo have not been reported. OBJECTIVE: The aim of this study was to determine whether DEX exhibits a preconditioning effect and reduces infarct size and the incidence and duration of arrhythmias in a regional cardiac ischemia/reperfusion model in rats...
April 2008: Current Therapeutic Research, Clinical and Experimental
https://www.readbyqxmd.com/read/24475841/cardiac-arrythmias-multimodal-assessment-integrating-body-surface-ecg-mapping-into-cardiac-imaging
#15
Hubert Cochet, Rémi Dubois, Frédéric Sacher, Nicolas Derval, Maxime Sermesant, Mélèze Hocini, Michel Montaudon, Michel Haïssaguerre, François Laurent, Pierre Jaïs
PURPOSE: To demonstrate the feasibility of comprehensive assessment of cardiac arrhythmias by combining body surface electrocardiographic (ECG) mapping (BSM) and imaging. MATERIALS AND METHODS: This study was approved by the institutional review board, and all patients gave written informed consent. Twenty-seven patients referred for electrophysiologic procedures in the context of ventricular tachycardia (VT) (n = 9), Wolff-Parkinson-White (WPW) syndrome (n = 2), atrial fibrillation (AF) (n = 13), or scar-related ventricular fibrillation (VF) (n = 3) were examined...
April 2014: Radiology
https://www.readbyqxmd.com/read/24424463/seizure-secondary-to-cardiac-arrythmias
#16
S K M Gardezi, R M Chalmers, N C Pegge
BACKGROUND: The relationship between seizure activity and arrhythmias is not well established. Sinus tachycardia is commonly seen post seizure. Bradyarrythmias leading to seizure activity is rarely reported in the literature thus far. CASE PRESENTATION: A 62-year-old lady presented with nocturnal seizures and was subsequently started on oral anti-convulsant with no relief of her symptoms. Further investigations led to outpatient ambulatory ECGs which showed marked sinus bradycardia prior to seizure activity and post seizure atrial fibrillation with fast ventricular rate...
February 2014: Scottish Medical Journal
https://www.readbyqxmd.com/read/24110315/on-chip-cellomics-single-cell-based-constructive-cell-network-assay-for-quasi-in-vivo-screening-of-cardiotoxicity
#17
Kenji Yasuda
We have developed methods and systems of analyzing epigenetic information in cells, as well as that of genetic information, to expand our understanding of how living systems are determined. A system of analyzing epigenetic information was developed starting from the twin complementary viewpoints of cell regulation as an 'algebraic' system (emphasis on temporal aspects) and as a 'geometric' system (emphasis on spatial aspects). As an example of the 'geometric' system, we have developed an quasi-in vivo hiPS cardiomyocyte network assay and confirmed that it can predict the risk of lethal arrythmia correctly in 22 compounds...
2013: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/24088470/successful-detection-and-surgical-treatment-of-cardiac-hemangioma-with-right-ventricular-invasion
#18
Yasunori Iida, Tsutomu Ito, Hiroto Kitahara, Motojiro Takebe, Atsushi Nemoto, Reiko Shimokawa, Akihiro Yoshitake, Takahiko Misumi
Cardiac hemangiomas are extremely rare benign tumors. These tumors are usually asymptomatic but they can present symptoms such as palpitations, shortness of breath, and arrythmia. We report the case of a 73-year-old man who presented with an abnormal shadow on chest computed tomography during follow-up for lung metastatic tumor after resection of his rectal cancer. A cardiac tumor was detected, and surgical resection and right ventricular plasty were successfully performed with the patient under cardiopulmonary bypass...
October 2013: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/24011300/dental-management-of-a-patient-with-catecholaminergic-polymorphic-ventricular-tachycardia-a-case-report
#19
Abimbola Olufunke Adewumi, Laura Grace Tucker
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a type of cardiac arrhythmia that occurs in people with a structurally normal heart. Stress or anxiety-induced release of endogenous catecholamines causes a dysfunction in the myocytic calcium-ion channel, leading to ventricular arrhythmias that can cause dizziness, syncope, or sudden cardiac death. Since dental procedures can be anxiety-provoking, the main purpose of this paper is to report the dental management of a young patient with dental fear and CPVT...
May 2013: Journal of Dentistry for Children
https://www.readbyqxmd.com/read/23834499/the-genetics-of-pro-arrhythmic-adverse-drug-reactions
#20
REVIEW
Evmorfia Petropoulou, Yalda Jamshidi, Elijah R Behr
Ventricular arrhythmia induced by drugs (pro-arrythmia) is an uncommon event, whose occurrence is unpredictable but potentially fatal. The ability of a variety of medications to induce these arrhythmias is a significant problem facing the pharmaceutical industry. Genetic variants have been shown to play a role in adverse events and are also known to influence an individual's optimal drug dose. This review provides an overview of the current understanding of the role of genetic variants in modulating the risk of drug induced arrhythmias...
April 2014: British Journal of Clinical Pharmacology
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