Rayn Clarenc Aarland, Angel Ernesto Bañuelos-Hernández, Mabel Fragoso-Serrano, Edgar Del Carmen Sierra-Palacios, Fernando Díaz de León-Sánchez, Laura Josefina Pérez-Flores, Fernando Rivera-Cabrera, José Alberto Mendoza-Espinoza
CONTEXT: Echinacea (Asteraceae) is used because of its pharmacological properties. However, there are few studies that integrate phytochemical analyses with pharmacological effects. OBJECTIVE: Evaluate the chemical profile and biological activity of hydroalcoholic Echinacea extracts. MATERIALS AND METHODS: Density, dry matter, phenols (Folin-Ciocalteu method), flavonoids (AlCl3 method), alkylamides (GC-MS analysis), antioxidant capacity (DPPH and ABTS methods), antiproliferative effect (SRB assay), anti-inflammatory effect (paw oedema assay, 11 days/Wistar rats; 0...
December 2017: Pharmaceutical Biology