Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#1
JOURNAL ARTICLE
Amandine Baudy, Nadia Raison-Peyron, Chris Serrand, Marie-Noëlle Crépy, Aurélie Du-Thanh
The impact of chronic urticaria on work has been scarcely reported, whereas its peak incidence is between the ages of 20 and 40. The aim of this study was to assess the occupational impact of chronic urticaria and its treatment, by combining objective and patient-reported data. A monocentric observational study was performed using questionnaires over a 1-year period from 2021 to 2022 in chronic urticaria patients who were in a period of professional activity and agreed to participate. Of the 88 patients included, 55...
March 29, 2024: Acta Dermato-venereologica
#2
JOURNAL ARTICLE
Julie Litovsky, Florence Hacard, Florence Tetart, Isabelle Boccon-Gibod, Angele Soria, Delphine Staumont-Salle, Marie-Sylvie Doutre, Emmanuelle Amsler, Catherine Mansard, Frederic Dezoteux, Anne-Sophie Darrigade, Brigitte Milpied, Claire Bernier, Jean-Luc Perrot, Nadia Raison-Peyron, Marie Paryl, Catherine Droitcourt, Pascal Demoly, Julien Grosjean, Thibault Mura, Aurelie Du-Thanh
BACKGROUND: Omalizumab (OMA) dramatically improves disease control and quality of life in patients with chronic urticaria (CU). OBJECTIVE: We aimed to evaluate the discontinuation patterns of OMA and their determinants in a cohort of French patients with CU. METHODS: We conducted a retrospective multicenter study in nine French tertiary referral hospitals. All patients diagnosed with either spontaneous (CSU) and/or inducible (CIndU) CU who received at least one injection of OMA between 2009 and 2021 were included...
August 29, 2023: Journal of Allergy and Clinical Immunology in Practice
#3
JOURNAL ARTICLE
Marie Douillard, Zineb Deheb, Agathe Bozon, Nadia Raison-Peyron, Olivier Dereure, Lionel Moulis, Angèle Soria, Aurélie Du-Thanh
BACKGROUND: Bradykinin angioedemas are a potentially serious side effect of angiotensin-converting enzyme inhibitors (ACEI) and more controversially of angiotensin II receptor blockers (ARB). Their challenging diagnosis is based on the absence of any recurrence after more than 6 months of drug discontinuation; otherwise mast-cell driven angioedemas as a differential diagnosis must be considered. OBJECTIVE: The aim of this study was to determine the prevalence of recurrent angioedema in patients referred for ACEI/ARB-induced bradykinin angioedema, after more than 6 months of drug discontinuation...
August 2023: World Allergy Organization Journal
#4
Manon Levêque, Nadim Cassir, Fanny Mathias, Cindy Fevre, Florence Daviet, Julien Bermudez, Geoffrey Brioude, Florence Peyron, Martine Reynaud-Gaubert, Benjamin Coiffard
Recipients transplanted for bronchiectasis in the context of a primary immune deficiency, such as common variable immunodeficiency, are at a high risk of severe infection in post-transplantation leading to poorer long-term outcomes than other transplant indications. In this report, we present a fatal case due to chronic Pseudomonas aeruginosa bronchopulmonary infection in a lung transplant recipient with common variable immunodeficiency despite successful eradication of an extensively drug-resistant (XDR) strain with IgM/IgA-enriched immunoglobulins and bacteriophage therapy...
2023: Infection and Drug Resistance
#5
Y Zhou, K Leahy, A Grose, J Lykins, M Siddiqui, N Leong, P Goodall, S Withers, K Ashi, S Schrantz, V Tesic, A P Abeleda, K Beavis, F Clouser, M Ismail, M Christmas, R Piarroux, D Limonne, E Chapey, S Abraham, I Baird, J Thibodeau, K Boyer, E Torres, S Conrey, K Wang, M A Staat, N Back, J Gomez Marin, F Peyron, S Houze, M Wallon, R McLeod
BACKGROUND: Congenital toxoplasmosis is a treatable, preventable disease, but untreated causes death, prematurity, loss of sight, cognition and motor function, and substantial costs worldwide. METHODS/FINDINGS: In our ongoing USA feasibility/efficacy clinical trial, data collated with other ongoing and earlier published results proved high performance of an Immunochromatographic-test(ICT) that enables accurate, rapid diagnosis/treatment, establishing new paradigms for care...
May 10, 2023: medRxiv
#6
JOURNAL ARTICLE
Mariangela Soberón Felín, Kanix Wang, Aliya Moreira, Andrew Grose, Karen Leahy, Ying Zhou, Fatima Alibana Clouser, Maryam Siddiqui, Nicole Leong, Perpetua Goodall, Morgan Michalowski, Mahmoud Ismail, Monica Christmas, Stephen Schrantz, Zuleima Caballero, Ximena Norero, Dora Estripeaut, David Ellis, Catalina Raggi, Catherine Castro, Claudia Rengifo-Herrera, Davina Moossazadeh, Margarita Ramirez, Abhinav Pandey, Kevin Ashi, Samantha Dovgin, Ashtyn Dixon, Xuan Li, Ian Begeman, Sharon Heichman, Joseph Lykins, Delba Villalobos-Cerrud, Lorena Fabrega, José Luis Sanchez Montalvo, Connie Mendivil, Mario R Quijada, Silvia Fernández-Pirla, Valli de La Guardia, Digna Wong, Mayrene Ladrón de Guevara, Carlos Flores, Jovanna Borace, Anabel García, Natividad Caballero, Maria Theresa Moreno de Saez, Michael Politis, Stephanie Ross, Mimansa Dogra, Vishan Dhamsania, Nicholas Graves, Marci Kirchberg, Kopal Mathur, Ashley Aue, Carlos M Restrepo, Alejandro Llanes, German Guzman, Arturo Rebellon, Kenneth Boyer, Peter Heydemann, A Gwendolyn Noble, Charles Swisher, Peter Rabiah, Shawn Withers, Teri Hull, David Frim, David McLone, Chunlei Su, Michael Blair, Paul Latkany, Ernest Mui, Daniel Vitor Vasconcelos-Santos, Alcibiades Villareal, Ambar Perez, Carlos Andrés Naranjo Galvis, Mónica Vargas Montes, Nestor Ivan Cardona Perez, Morgan Ramirez, Cy Chittenden, Edward Wang, Laura Lorena Garcia-López, Juliana Muñoz-Ortiz, Nicolás Rivera-Valdivia, María Cristina Bohorquez-Granados, Gabriela Castaño de-la-Torre, Guillermo Padrieu, Juan David Valencia Hernandez, Daniel Celis-Giraldo, John Alejandro Acosta Dávila, Elizabeth Torres, Manuela Mejia Oquendo, José Y Arteaga-Rivera, Dan L Nicolae, Andrey Rzhetsky, Nancy Roizen, Eileen Stillwaggon, Larry Sawers, Francois Peyron, Martine Wallon, Emanuelle Chapey, Pauline Levigne, Carmen Charter, Migdalia De Frias, Jose Montoya, Cindy Press, Raymund Ramirez, Despina Contopoulos-Ioannidis, Yvonne Maldonado, Oliver Liesenfeld, Carlos Gomez, Kelsey Wheeler, Samantha Zehar, James McAuley, Denis Limonne, Sandrine Houze, Sylvie Abraham, Raphael Piarroux, Vera Tesic, Kathleen Beavis, Ana Abeleda, Mari Sautter, Bouchra El Mansouri, Adlaoui El Bachir, Fatima Amarir, Kamal El Bissati, Ellen Holfels, Richard Penn, William Cohen, Alejandra de-la-Torre, Gabrielle Britton, Jorge Motta, Eduardo Ortega-Barria, Isabel Luz Romero, Paul Meier, Michael Grigg, Jorge Gómez-Marín, Jagannatha Rao Kosagisharaf, Xavier Sáez Llorens, Osvaldo Reyes, Rima McLeod
PURPOSE OF REVIEW: Review work to create and evaluate educational materials that could serve as a primary prevention strategy to help both providers and patients in Panama, Colombia, and the USA reduce disease burden of Toxoplasma infections. RECENT FINDINGS: Educational programs had not been evaluated for efficacy in Panama, USA, or Colombia. SUMMARY: Educational programs for high school students, pregnant women, medical students and professionals, scientists, and lay personnel were created...
September 2022: Current Pediatrics Reports
#7
REVIEW
Justus G Garweg, François Kieffer, Laurent Mandelbrot, François Peyron, Martine Wallon
Even in the absence of manifestations at birth, children with congenital toxoplasmosis (CT) may develop serious long-term sequelae later in life. This systematic review aims to present the current state of knowledge to base an informed decision on how to optimally manage these pregnancies and children. For this, a systematic literature search was performed on 28 July 2022 in PubMed, CENTRAL, ClinicalTrials.gov, Google Scholar and Scopus to identify all prospective and retrospective studies on congenital toxoplasmosis and its long-term outcomes that were evaluated by the authors...
October 15, 2022: Pathogens
#8
JOURNAL ARTICLE
Pauline Voland, Camille Barthel, Brahim Azzouz, Nadia Raison-Peyron, Aurélie Du-Thanh, Delphine Staumont-Sallé, Marie Jachiet, Angèle Soria, Audrey Nosbaum, Aude Valois, Camille Leleu, Bénédicte Lebrun-Vignes, Thierry Trenque, Dominique Hettler, Claire Bernier, Manuelle Viguier
BACKGROUND: Human immunoglobulins (Ig) are used for treating diverse inflammatory and auto-immune disorders. Eczema is an adverse event reported but poorly described. OBJECTIVES: To describe the clinical presentation, severity, outcome, and therapeutic management of Ig-associated eczema. METHODS: This retrospective and descriptive study included a query of the French national pharmacovigilance database, together with a national call for cases among dermatologists...
October 14, 2022: Journal of the American Academy of Dermatology
#9
REVIEW
Silvia Melzi, Vincent Prevot, Christelle Peyron
Narcolepsy type 1 (NT1) is a rare neurological sleep disorder triggered by postnatal loss of the orexin/hypocretin neuropeptides. Overweight/obesity and precocious puberty are highly prevalent comorbidities of NT1, with a close temporal correlation with disease onset, suggesting a common origin. However, the underlying mechanisms remain unknown and merit further investigation. The main question we address in this review is whether the occurrence of precocious puberty in NT1 is due to the lack of orexin/hypocretin or rather to a wider hypothalamic dysfunction in the context of neuroinflammation, which is likely to accompany the disease given its autoimmune origins...
September 9, 2022: Sleep Medicine Reviews
#10
JOURNAL ARTICLE
Pierre Bertholon, Laure Mazzola, Marie Gavid, Alexandre Karkas, Roland Peyron, Philippe Convers
OBJECTIVES: The main objective was to describe the nystagmus observed during benign paroxysmal vertigo (BPV) of childhood, which is one of the criteria included in the three versions of the International Classification of Headache Disorders that has never been specified. The secondary objectives were to emphasize the usefulness of a mobile phone to record nystagmus and discuss the physiopathology of this nystagmus. PATIENT: A 6-year-old boy complained of approximately 30 to 50 vertigo attacks, most of them lasting around 1 minute, during a 6-month period...
October 1, 2022: Otology & Neurotology
#11
REVIEW
Mariangela Soberón Felín, Kanix Wang, Aliya Moreira, Andrew Grose, Karen Leahy, Ying Zhou, Fatima Alibana Clouser, Maryam Siddiqui, Nicole Leong, Perpetua Goodall, Morgan Michalowski, Mahmoud Ismail, Monica Christmas, Stephen Schrantz, Zuleima Caballero, Ximena Norero, Dora Estripeaut, David Ellis, Catalina Raggi, Catherine Castro, Davina Moossazadeh, Margarita Ramirez, Abhinav Pandey, Kevin Ashi, Samantha Dovgin, Ashtyn Dixon, Xuan Li, Ian Begeman, Sharon Heichman, Joseph Lykins, Delba Villalobos-Cerrud, Lorena Fabrega, José Luis Sanchez Montalvo, Connie Mendivil, Mario R Quijada, Silvia Fernández-Pirla, Valli de La Guardia, Digna Wong, Mayrene Ladrón de Guevara, Carlos Flores, Jovanna Borace, Anabel García, Natividad Caballero, Claudia Rengifo-Herrera, Maria Theresa Moreno de Saez, Michael Politis, Stephanie Ross, Mimansa Dogra, Vishan Dhamsania, Nicholas Graves, Marci Kirchberg, Kopal Mathur, Ashley Aue, Carlos M Restrepo, Alejandro Llanes, German Guzman, Arturo Rebellon, Kenneth Boyer, Peter Heydemann, A Gwendolyn Noble, Charles Swisher, Peter Rabiah, Shawn Withers, Teri Hull, David Frim, David McLone, Chunlei Su, Michael Blair, Paul Latkany, Ernest Mui, Daniel Vitor Vasconcelos-Santos, Alcibiades Villareal, Ambar Perez, Carlos Andrés Naranjo Galvis, Mónica Vargas Montes, Nestor Ivan Cardona Perez, Morgan Ramirez, Cy Chittenden, Edward Wang, Laura Lorena Garcia-López, Guillermo Padrieu, Juliana Muñoz-Ortiz, Nicolás Rivera-Valdivia, María Cristina Bohorquez-Granados, Gabriela Castaño de-la-Torre, Juan David Valencia Hernandez, Daniel Celis-Giraldo, Juan Alejandro Acosta Dávila, Elizabeth Torres, Manuela Mejia Oquendo, José Y Arteaga-Rivera, Dan L Nicolae, Andrey Rzhetsky, Nancy Roizen, Eileen Stillwaggon, Larry Sawers, Francois Peyron, Martine Wallon, Emanuelle Chapey, Pauline Levigne, Carmen Charter, Migdalia De Frias, Jose Montoya, Cindy Press, Raymund Ramirez, Despina Contopoulos-Ioannidis, Yvonne Maldonado, Oliver Liesenfeld, Carlos Gomez, Kelsey Wheeler, Samantha Zehar, James McAuley, Denis Limonne, Sandrine Houze, Sylvie Abraham, Raphael Piarroux, Vera Tesic, Kathleen Beavis, Ana Abeleda, Mari Sautter, Bouchra El Mansouri, Adlaoui El Bachir, Fatima Amarir, Kamal El Bissati, Ellen Holfels, David Frim, David McLone, Richard Penn, William Cohen, Alejandra de-la-Torre, Gabrielle Britton, Jorge Motta, Eduardo Ortega-Barria, Isabel Luz Romero, Paul Meier, Michael Grigg, Jorge Gómez-Marín, Jagannatha Rao Kosagisharaf, Xavier Sáez Llorens, Osvaldo Reyes, Rima McLeod
Purpose of Review: Review international efforts to build a global public health initiative focused on toxoplasmosis with spillover benefits to save lives, sight, cognition and motor function benefiting maternal and child health. Recent Findings: Multiple countries' efforts to eliminate toxoplasmosis demonstrate progress and context for this review and new work. Summary: Problems with potential solutions proposed include accessibility of accurate, inexpensive diagnostic testing, pre-natal screening and facilitating tools, missed and delayed neonatal diagnosis, restricted access, high costs, delays in obtaining medicines emergently, delayed insurance pre-approvals and high medicare copays taking considerable physician time and effort, harmful shortcuts being taken in methods to prepare medicines in settings where access is restricted, reluctance to perform ventriculoperitoneal shunts promptly when needed without recognition of potential benefit, access to resources for care, especially for marginalized populations, and limited use of recent advances in management of neurologic and retinal disease which can lead to good outcomes...
August 16, 2022: Current Pediatrics Reports
#12
JOURNAL ARTICLE
A Lasek, N Bellon, S Mallet, E Puzenat, A C Bursztejn, C Abasq, J Mazereeuw-Hautier, C Chiaverini, T Hubiche, N Raison Peyron, A Du Thanh, S Barbarot, H Aubert, Z Reguiai, C Droitcourt, C Fievet, A Bellissen, M Bachelerie, A Nosbaum, A Leymarie, P Armingaud, M Masson Regnault, E Mahé
BACKGROUND: Dupilumab is the first biotherapy available for the treatment of moderate-to-severe childhood atopic dermatitis (AD). OBJECTIVE: The aim of this study was to evaluate the effectiveness and safety of dupilumab in daily practice. METHODS: Patients aged 6 to 11, who had received a first dose of dupilumab were included in this multicenter retrospective cohort study. The primary endpoint was change in SCORAD after 3 months of treatment...
July 19, 2022: Journal of the European Academy of Dermatology and Venereology: JEADV
#13
JOURNAL ARTICLE
Marie-Daniéla Dubois, Ivan Peyron, Olivier-Nicolas Pierre-Louis, Serge Pierre-Louis, Johalène Rabout, Pierre Boisseau, Annika de Jong, Sophie Susen, Jenny Goudemand, Rémi Neviere, Pascal Fuseau, Olivier D Christophe, Peter J Lenting, Cécile V Denis, Caterina Casari
Background: Von Willebrand disease was diagnosed in two Afro-Caribbean patients and sequencing of the VWF gene ( VWF ) revealed the presence of multiple variants located throughout the gene, including variants located in the D4 domain of VWF: p.(Pro2145Thrfs*5) in one patient and p.(Cys2216Phefs*9) in the other patient. Interestingly, D4 variants have not been studied often. Objectives: Our goal was to characterize how the D4 variants p.(Pro2145Thrfs*5) and p.(Cys2216Phefs*9) influenced VWF biosynthesis/secretion and functions using in vitro assays...
May 2022: Research and Practice in Thrombosis and Haemostasis
#14
JOURNAL ARTICLE
Raphaël Bernard-Valnet, David Frieser, Xuan Hung Nguyen, Leila Khajavi, Clémence Quériault, Sébastien Arthaud, Silvia Melzi, Maxime Fusade-Boyer, Frederick Masson, Matthias Zytnicki, Abdelhadi Saoudi, Yves Dauvilliers, Christelle Peyron, Jan Bauer, Roland S Liblau
Narcolepsy with cataplexy or narcolepsy type 1 is a disabling chronic sleep disorder resulting from the destruction of orexinergic neurons in the hypothalamus. The tight association of narcolepsy with HLA-DQB1*06:02 strongly suggest an autoimmune origin to this disease. Furthermore, converging epidemiological studies have identified an increased incidence for narcolepsy in Europe following Pandemrix® vaccination against the 2009-2010 pandemic 'influenza' virus strain. The potential immunological link between the Pandemrix® vaccination and narcolepsy remains, however, unknown...
June 30, 2022: Brain
#15
JOURNAL ARTICLE
Raphaël Bonnet, Lee Mariault, Jean-François Peyron
Drug repurposing can be an interesting strategy for an emergency response to the severe acute respiratory syndrome-coronavirus-2, (SARS-COV-2), the causing agent of the coronavirus disease-19 (COVID-19) pandemic. For this, we applied the Connectivity Map (CMap) bioinformatic resource to identify drugs that generate, in the CMap database, gene expression profiles (GEP) that negatively correlate with a SARS-COV-2 GEP, anticipating that these drugs could antagonize the deleterious effects of the virus at cell, tissue or organism levels...
2022: PloS One
#16
REVIEW
Stéphane J C Mancini, Karl Balabanian, Isabelle Corre, Julie Gavard, Gwendal Lazennec, Marie-Caroline Le Bousse-Kerdilès, Fawzia Louache, Véronique Maguer-Satta, Nathalie M Mazure, Fatima Mechta-Grigoriou, Jean-François Peyron, Valérie Trichet, Olivier Herault
Knowledge about the hematopoietic niche has evolved considerably in recent years, in particular through in vitro analyzes, mouse models and the use of xenografts. Its complexity in the human bone marrow, in particular in a context of hematological malignancy, is more difficult to decipher by these strategies and could benefit from the knowledge acquired on the niches of solid tumors. Indeed, some common features can be suspected, since the bone marrow is a frequent site of solid tumor metastases. Recent research on solid tumors has provided very interesting information on the interactions between tumoral cells and their microenvironment, composed notably of mesenchymal, endothelial and immune cells...
2021: Frontiers in Immunology
#17
JOURNAL ARTICLE
Silvia Melzi, Anne-Laure Morel, Céline Scoté-Blachon, Roland Liblau, Yves Dauvilliers, Christelle Peyron
An increased number of histaminergic neurons, identified by labeling histidine-decarboxylase (HDC) its synthesis enzyme, was unexpectedly found in patients with narcolepsy type 1 (NT1). In quest for enlightenment, we evaluate whether an increase in HDC cell number and expression level would be detected in mouse models of the disease, in order to provide proof of concepts reveling possible mechanisms of compensation for the loss of orexin neurons, and/or of induced expression as a consequence of local neuroinflammation, a state that likely accompanies NT1...
October 21, 2021: Brain Pathology
#18
JOURNAL ARTICLE
Quentin Samaran, Evangéline Clark, Léo-Paul Secco, Laura Poujade, Emilie Schwob, Didier Bessis, Nadia Raison-Peyron
Granulomatous dermatitis following the administration of various vaccines has previously been reported. However, cases of cutaneous granulomatosis following the measles, mumps, and rubella (MMR) vaccine have not yet been reported. We report the case of a 3-year-old boy with a granuloma annulare-like reaction following MMR vaccination.
September 2021: Pediatric Dermatology
#19
JOURNAL ARTICLE
Bouchra El Mansouri, Fatima Amarir, Francois Peyron, El Bachir Adlaoui, Raphael Piarroux, Joseph Lykins, Majda El Abbassi, Nesma Nekkal, Nadia Bouhlal, Kamar Makkaoui, Amina Barkat, Aziza Lyaghfouri, Ying Zhou, Samira Rais, Mounia Oudghiri, Ismail Elkoraichi, Mustapha Zekri, Nezha Belkadi, Hajar Mellouk, Mohamed Rhajaoui, Allal Boutajangout, Abderrahim Sadak, Denis Limonne, Rima McLeod, Kamal El Bissati
Point-of-care (POC) testing for Toxoplasma infection has the potential to revolutionize diagnosis and management of toxoplasmosis, especially in high-risk populations in areas with significant environmental contamination and poor health infrastructure precluding appropriate follow-up and preventing access to medical care. Toxoplasmosis is a significant public health challenge in Morocco, with a relatively heavy burden of infection and, to this point, minimal investment nationally to address this infection. Herein, we analyze the performance of a novel, low-cost rapid test using fingerstick-derived whole blood from 632 women (82 of whom were pregnant) from slums, educational centers, and from nomad groups across different geographical regions (i...
June 24, 2021: Emerging Microbes & Infections
#20
JOURNAL ARTICLE
Damien Dupont, Jian-Sheng Lin, François Peyron, Hideo Akaoka, Martine Wallon
AIM: Toxoplasma gondii (Tg) is an intracellular parasite infecting more than a third of the human population. Yet, the impact of Tg infection on sleep, a highly sensitive index of brain functions, remains unknown. We designed an experimental mouse model of chronic Tg infection to assess the effects on sleep-wake states. METHODS: Mice were infected using cysts of the type II Prugniaud strain. We performed chronic sleep-wake recordings and monitoring as well as EEG power spectral density analysis in order to assess the quantitative and qualitative changes of sleep-wake states...
June 4, 2021: CNS Neuroscience & Therapeutics
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
