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Balan Banumathi, Baskaralingam Vaseeharan, Periyannan Rajasekar, Narayanan Marimuthu Prabhu, Palaniappan Ramasamy, Kadarkarai Murugan, Angelo Canale, Giovanni Benelli
The tick Rhipicephalus (Boophilus) microplus is a key vector of bacterial and protozoan diseases causing heavy economic losses directly and indirectly in animal husbandry. In the past decades, the control of ticks faced some major issues, such as the rapid development of resistance in targeted vectors and non-target effects on human health and the environment, due to the employ of synthetic acaricides and repellents. Eco-friendly pesticides for treating and controlling animal parasites such as ticks were mainly from medicinal plants and thus they form the richest entity for manufacturing resources for drugs...
September 15, 2017: Veterinary Parasitology
Yong Zhang, Jia Fan, Frederic Francis, Julian Chen
Infestation with Sitobion avenae induces localized defense responses in wheat; in this study, the role of S. avenae watery saliva in resistance induction was examined by infiltrating aphid saliva into wheat leaves. After feeding S. avenae on an artificial diet for 48 h, we first collected watery saliva from them and then separated the salivary proteins using one-dimensional gel electrophoresis. Gene expression studies showed that infiltration of S. avenae watery saliva in wheat leaves induced strong salicylic acid-responsive defense but moderate jasmonic acid-dependent defense...
September 15, 2017: Journal of Agricultural and Food Chemistry
Raphael S Affonso, Josélia A Lima, Bruno Lessa, João V O Caetano, Marcos T Obara, Andrea Nóbrega, Eugenie Nepominova, Kamil Musilek, Kamil Kuca, Gláucia Barbosa Candido Alves Slana, Tanos C C França
The rise of mosquito's transmitted diseases, like dengue, zika and chikungunya in Brazil in the last years has increased the concerns on protection against mosquito's bites. However, the prohibitive prices of the commercially available repellents for the majority of the Brazilian population, has provoked a search for cheaper solutions, like the use of the homemade ethanolic extract of Indian clove (Syzygium aromaticum L.) as repellent, which has been reported as quite efficient by the local press. In order to verify this, we performed here, the quantification of the main components of this extract through high-performance thin-layer chromatography (HPTLC)-densitometry and evaluated its efficiency as repellent, as well as the acetylcholinesterase (AChE) inhibition capacity...
September 15, 2017: Biomedical Chromatography: BMC
Yinliang Wang, Qi Chen, Junqi Guo, Jing Li, Jiatong Wang, Ming Wen, Hanbo Zhao, Bingzhong Ren
Anastatus japonicus is a parasitic wasp and natural enemy of the litchi pest Tessaratoma papillosa, and for decades in China, A. japonicus has been mass-reared inside the eggs of Antheraea pernyi to control T. papillosa. A series of experiments was performed to explore the olfactory mechanism underlying the oviposition behavior of A. japonicus. First, a transcriptomic analysis was performed on the antennae of A. japonicus, and the resulting assemblies led to the generation of 70,473 unigenes. Subsequently, 21,368 unigenes were matched to known proteins, and 48 odorant receptors (ORs) (including Orco) and 13 antennal ionotropic receptors (IRs) (including the co-receptors IR8a and IR25a) were identified and predicted to form complete open reading frames (ORFs)...
September 11, 2017: Insect Biochemistry and Molecular Biology
Margaret Mcallister, Donna Lee Brien, Lorna Piatti-Farnell
AIMS: To discuss representations of nursing in popular culture using the Contemporary Gothic theory. BACKGROUND: Nursing is stereotypically known as a caring profession. Caring in both the natural and professional perspectives is inextricably attached to love and love, we are told, is universal. In popular culture, however, there are numerous examples of nurses being portrayed in ways where love - its expression and its practice - has been transgressed or tainted...
September 14, 2017: Journal of Advanced Nursing
Jingda Huang, Siqun Wang, Shaoyi Lyu
It is a challenge for a superhydrophobic coating to overcome the poor robustness and the rough surface structure that is usually built using inorganic particles that are difficult to degrade. In this study, a robust superhydrophobic coating is facilely prepared by using commercial biodegradable lignin-coated cellulose nanocrystal (L-CNC) particles after hydrophobic modification to build rough surface structures, and by choosing two different adhesives (double-sided tape and quick-setting epoxy) to support adhesion between the L-CNC particles and the substrates...
September 14, 2017: Materials
Wint Phyo Than, Tin Oo, Khin Thet Wai, Aung Thi, Philip Owiti, Binay Kumar, Hemant Deepak Shewade, Rony Zachariah
BACKGROUND: Myanmar lies in the Greater Mekong sub-region of South-East Asia faced with the challenge of emerging resistance to artemisinin combination therapies (ACT). Migrant populations are more likely than others to spread ACT resistance. A vital intervention to reduce malaria transmission, resistance spread and eliminate malaria is the use of bed nets. Among seasonal and stable migrants in an artemisinin resistance containment region of Myanmar, we compared a) their household characteristics, b) contact with health workers and information material, and c) household knowledge, access and utilization of bed nets...
September 14, 2017: Infectious Diseases of Poverty
Chenjie Yao, Yusong Tu, Lin Ding, Chenchen Li, Jiao Wang, Haiping Fang, Yanan Huang, Kangkang Zhang, Quan Lu, Minghong Wu, Yanli Wang
Specific targeting of tumor tissues is essential for tumor imaging and therapeutics but remains challenging. Here, we report an unprecedented method using synthetic sulfonic-graphene quantum dots (sulfonic-GQDs) to exactly target the cancer cell nuclei in vivo without any bio- ligand modification, with no intervention in cells of normal tissues. The key factor for such selectivity is the high interstitial fluid pressure (IFP) in tumor tissues, which allows the penetration of sulfonic-GQDs into the plasma membrane of tumor cells...
September 13, 2017: Bioconjugate Chemistry
Mario Abbate, Loredana D'Orazio
Water diffusion through a TiO₂/poly (carbonate urethane) nanocomposite designed for the eco-sustainable protection of outdoor cultural heritage stonework was investigated. Water is recognized as a threat to heritage, hence the aim was to gather information on the amount of water uptake, as well as of species of water molecules absorbed within the polymer matrix. Gravimetric and vibrational spectroscopy measurements demonstrated that diffusion behavior of the nanocomposite/water system is Fickian, i.e., diffusivity is independent of concentration...
September 13, 2017: Nanomaterials
Gi-Hwan Kim, Hyungsu Jang, Yung Jin Yoon, Jaeki Jeong, Song Yi Park, Bright Walker, In-Yup Jeon, Yimhyun Jo, Hyun Yoon, Minjin Kim, Jong-Beom Baek, Dong Suk Kim, Jin Young Kim
Edged-selectively fluorine (F) functionalized graphene nanoplatelets (EFGnPs-F) with a p-i-n structure of perovskite solar cells achieved 82% stability relative to initial performance over 30 days of air exposure without encapsulation. The enhanced stability stems from F-substitution on EFGnPs; fluorocarbons such as polytetrafluoroethylene are well-known for their superhydrophobic properties and being impervious to chemical degradation. These hydrophobic moieties tightly protect perovskite layers from air degradation...
September 14, 2017: Nano Letters
Biyu Jin, Mingzhu Liu, Qinghua Zhang, Xiaoli Zhan, Fengqiu Chen
In this work, a novel substrate building block, magnetic Fe3O4 nanoparticles (MNPs) armed with dopamine molecules were developed via mussel-inspired metal-coordination bonds. Combined with glycidyl methacrylate, polydimethylsiloxane (PDMS) and diethylenetriamine (DETA), the original silicone oil swelling SLIPS (SPG-MNP) owning ability to heal the matrix itself were first prepared by reversible coordinate bonds and strong covalent bonds crosslinking process. The matrix mechanical characteristics and surface physicochemical properties were also systematically investigated...
September 11, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
Masuro Funaki, Masayori Suwa, Hitoshi Watarai
The electromagnetophoretic behavior of organic droplets in an electrolyte solution was investigated in a silica capillary cell using a superconducting bulk magnet (3.5 T) and a magnetic circuit (2.7 T). The initially dispersed emulsion droplets of dodecane migrated to the wall of the capillary, responding to the direction of an electric current, and coalesced to form smaller and larger droplets after some repeated migrations. When the electric current was applied continuously, the larger droplets became arranged with regular intervals on the wall, and smaller droplets rotated around the larger droplets...
2017: Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry
Suryendu Dutta, Rakesh C Mehrotra, Swagata Paul, R P Tiwari, Sharmila Bhattacharya, Gaurav Srivastava, V Z Ralte, C Zoramthara
Plants produce and release a large array of volatile organic compounds that play many ecological functions. These volatile plant metabolites serve as pollinator attractants, herbivore and pathogen repellents and protect plants from abiotic stresses. To date, the geological evolution of these organic compounds remains unknown. The preservation potential of these metabolites in the fossil record is very poor due to their low boiling points. Here we report a series of volatile sesquiterpenoids, including δ-elemene, α-copaene, β-elemene, β-caryophyllene, α-humulene, germacrene D, δ-cadiene and spathunenol, from early Miocene (~17 million year) amber from eastern India...
September 8, 2017: Scientific Reports
Ke Zhang, Ning Zhang, Michael D Weir, Mark A Reynolds, Yuxing Bai, Hockin H K Xu
Current dental restorative materials are typically inert and replace missing tooth structures. This article reviews efforts in the development of a new generation of bioactive materials designed to not only replace the missing tooth volume but also possess therapeutic functions. Composites and bonding agents with remineralizing and antibacterial characteristics have shown promise in replacing lost minerals, inhibiting recurrent caries, neutralizing acids, repelling proteins, and suppressing biofilms and acid production...
October 2017: Dental Clinics of North America
Chisato Morino, Yusuke Morita, Kazuki Minami, Yuto Nishidono, Yoshitaka Nakashima, Rika Ozawa, Junji Takabayashi, Naoaki Ono, Shigehiko Kanaya, Takayuki Tamura, Yasuhiro Tezuka, Ken Tanaka
Umbelliferous medicinal plants, such as Angelica acutiloba Kitagawa and Angelica dahurica Bentham et Hooker filius ex Franchet et Savatier, account for a large percentage of crude drug consumption in Japan. The most serious problem in the cultivation of umbelliferous medicinal plants is the feeding damage caused by the common yellow swallowtail (Papilio machaon hippocrates C. & R. Felder, 1864). When we compared the numbers of eggs laid by P. machaon on six umbelliferous medicinal plants, the eggs on A. acutiloba, A...
September 7, 2017: Journal of Natural Medicines
Chen Chen, Junling Wu, Michael D Weir, Lin Wang, Xuedong Zhou, Hockin H K Xu, Mary Anne S Melo
Fracture and secondary caries are the primary reasons for the failure of dental restorations. To face this omnipresent problem, we report the formulation design and synthesis of a protein-resistant dental composite composed of 2-methacryloyloxyethyl phosphorylcholine (MPC) that also can self-repair damage and recover the load-bearing capability via microencapsulated triethylene glycol dimethacrylate (TEGDMA) and N,N-dihydroxy ethyl-p-toluidine (DHEPT). The bioactivity of the resulting MPC-microencapsulated TEGDMA-DHEPT was evaluated on protein adsorption through early bacterial attachment...
September 7, 2017: Journal of Functional Biomaterials
Rasmus H Gantzel, Louise S Mogensen, Stine A Mikkelsen, Bente Vilsen, Robert S Molday, Anna L Vestergaard, Jens P Andersen
Phospholipid flippases (P4-ATPases) translocate specific phospholipids from the exoplasmic to the cytoplasmic leaflet of membranes. While there is good evidence that the overall molecular structure of flippases is similar to that of P-type ATPase ion-pumps, the transport pathway for the "giant" lipid substrate has not been determined. ATP8A2 is a flippase with selectivity toward phosphatidylserine (PS), possessing a net negatively charged head group, whereas ATP8B1 exhibits selectivity toward the electrically neutral phosphatidylcholine (PC)...
September 5, 2017: Scientific Reports
Tae-Woon Kang, Sung Hyun Kim, Cheol Hwan Kim, Sang-Mok Lee, Han-Ki Kim, Jae Seong Park, Jae Heung Lee, Yong Suk Yang, Sang-Jin Lee
Polymer/metal/polymer and polymer/metal/inorganic trilayer-structured transparent electrodes with fluorocarbon plasma polymer thin film heaters have been proposed. The polymer/metal/polymer and polymer/metal/inorganic transparent conducting thin films fabricated on a large-area flexible polymer substrate using a continuous roll-to-roll sputtering process show excellent electrical properties and visible-light transmittance. They also exhibit water-repelling surfaces to prevent wetting and to remove contamination...
September 14, 2017: ACS Applied Materials & Interfaces
Daeyeon Kim, Mar Alvarez, Laura M Lechuga, Matthieu Louis
Animals explore their environment to encounter suitable food resources. Despite its vital importance, this behavior puts individuals at risk by consuming limited internal energy during locomotion. We have developed a novel assay to investigate how food-search behavior is organized in Drosophila melanogaster larvae dwelling in hydrogels mimicking their natural habitat. We define three main behavioral modes: resting at the gel's surface, digging while feeding near the surface, and apneic dives. In unstimulated conditions, larvae spend most of their time digging...
September 5, 2017: ELife
Raghu R Edupuganti, Simon Geiger, Rik G H Lindeboom, Hailing Shi, Phillip J Hsu, Zhike Lu, Shuang-Yin Wang, Marijke P A Baltissen, Pascal W T C Jansen, Martin Rossa, Markus Müller, Hendrik G Stunnenberg, Chuan He, Thomas Carell, Michiel Vermeulen
RNA modifications are integral to the regulation of RNA metabolism. One abundant mRNA modification is N(6)-methyladenosine (m(6)A), which affects various aspects of RNA metabolism, including splicing, translation and degradation. Current knowledge about the proteins recruited to m(6)A to carry out these molecular processes is still limited. Here we describe comprehensive and systematic mass-spectrometry-based screening of m(6)A interactors in various cell types and sequence contexts. Among the main findings, we identified G3BP1 as a protein that is repelled by m(6)A and positively regulates mRNA stability in an m(6)A-regulated manner...
September 4, 2017: Nature Structural & Molecular Biology
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