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skeletal muscle quality

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https://www.readbyqxmd.com/read/28207619/iliac-crest-regeneration-a-retrospective-study-of-14-years-of-follow-up
#1
Anastasios Christodoulou, Achilleas Boutsiadis, Evangellos Christodoulou, Petros Antonarakos, Panagiotis Givissis, Ippokratis Hatzokos
STUDY DESIGN: This is a retrospective study analysis. OBJECTIVE: The purpose of our study was to evaluate the healing process of the ilium after being used as a bone graft donor site in the treatment of adolescent idiopathic scoliosis. SUMMARY OF BACKGROUND DATA: Iliac crest bone grafts have been proven to be the most reliable means for solid fusion in spine surgery. Nevertheless, few reports in the literature describe the ability of the iliac crest to regenerate...
March 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28204990/skeletal-muscle-loss-and-prognosis-of-breast-cancer-patients
#2
Yoshiko Kubo, Tateaki Naito, Keita Mori, Gakuji Osawa, Etsuko Aruga
PURPOSE: The aim of this study was to clarify the changes in the cross-sectional area of skeletal muscle and muscle attenuation (MA) during 12-month period before death in breast cancer patients. METHODS: Breast cancer patients who received treatment between September 2002 and July 2014 at Shizuoka Cancer Center or between December 2005 and July 2014 at Teikyo University Hospital were identified. Computed tomography (CT) scans during the 12-month period before death of consecutive female patients who died of breast cancer were reviewed...
February 15, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28197275/cardiac-resynchronization-therapy-leads-to-improvements-in-handgrip-strength
#3
David R Warriner, Patricia Lawford, Paul J Sheridan
BACKGROUND: A reduction in skeletal muscle performance measured by handgrip strength is common in heart failure. No trial has investigated the role of cardiac resynchronization therapy, which leads to improvements in cardiac performance, on the function of skeletal muscle in patients with heart failure. METHODS: Nineteen patients were recruited, 18 male, age 69 ± 8 years, New York Heart Association class II-IV, QRS duration 173 ± 21 ms and left ventricular ejection fraction 26±8%...
June 2016: Cardiology Research
https://www.readbyqxmd.com/read/28192790/systemic-pharmacologic-therapies-for-low-back-pain-a-systematic-review-for-an-american-college-of-physicians-clinical-practice-guideline
#4
Roger Chou, Richard Deyo, Janna Friedly, Andrea Skelly, Melissa Weimer, Rochelle Fu, Tracy Dana, Paul Kraegel, Jessica Griffin, Sara Grusing
Background: A 2007 American College of Physicians guideline addressed pharmacologic options for low back pain. New evidence and medications have now become available. Purpose: To review the current evidence on systemic pharmacologic therapies for acute or chronic nonradicular or radicular low back pain. Data Sources: Ovid MEDLINE (January 2008 through November 2016), Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and reference lists...
February 14, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28192789/noninvasive-treatments-for-acute-subacute-and-chronic-low-back-pain-a-clinical-practice-guideline-from-the-american-college-of-physicians
#5
Amir Qaseem, Timothy J Wilt, Robert M McLean, Mary Ann Forciea
Description: The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations on noninvasive treatment of low back pain. Methods: Using the ACP grading system, the committee based these recommendations on a systematic review of randomized, controlled trials and systematic reviews published through April 2015 on noninvasive pharmacologic and nonpharmacologic treatments for low back pain. Updated searches were performed through November 2016...
February 14, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28181388/muscle-strength-mediates-the-relationship-between-mitochondrial-energetics-and-walking-performance
#6
Ariel C Zane, David A Reiter, Michelle Shardell, Donnie Cameron, Eleanor M Simonsick, Kenneth W Fishbein, Stephanie A Studenski, Richard G Spencer, Luigi Ferrucci
Skeletal muscle mitochondrial oxidative capacity declines with age and negatively affects walking performance, but the mechanism for this association is not fully clear. We tested the hypothesis that impaired oxidative capacity affects muscle performance and, through this mechanism, has a negative effect on walking speed. Muscle mitochondrial oxidative capacity was measured by in vivo phosphorus magnetic resonance spectroscopy as the postexercise phosphocreatine resynthesis rate, kPCr , in 326 participants (154 men), aged 24-97 years (mean 71), in the Baltimore Longitudinal Study of Aging...
February 9, 2017: Aging Cell
https://www.readbyqxmd.com/read/28179228/dietary-nitrate-does-not-reduce-oxygen-cost-of-exercise-or-improve-muscle-mitochondrial-function-in-mitochondrial-myopathy-patients
#7
Miranda Nabben, Joep P J Schmitz, Jolita Ciapaite, Carlijn M P Le Clercq, Natal A van Riel, Harm R Haak, Klaas Nicolay, Irenaeus F de Coo, Hubert J M Smeets, Stephan F Praet, Luc J C van Loon, Jeanine J Prompers
Muscle weakness and exercise intolerance negatively affect the quality of life of mitochondrial myopathy patients. Short-term dietary nitrate supplementation has been shown to improve exercise performance and reduce oxygen cost of exercise in healthy humans and trained athletes. We investigated if 1 week of dietary inorganic nitrate supplementation decreases the oxygen cost of exercise and improves mitochondrial function in mitochondrial myopathy patients. Ten mitochondrial myopathy patients (40 ± 5 years, maximal whole-body oxygen uptake = 21...
February 8, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28167172/musicians-postural-quality-and-musculoskeletal-health-a-literature-s-review
#8
Patricia Blanco-Piñeiro, M Pino Díaz-Pereira, Aurora Martínez
OBJECTIVE: An analysis of the salient characteristics of research papers published between 1989 and 2015 that evaluate the relationship between postural quality during musical performance and various performance quality and health factors, with emphasis on musculoskeletal health variables. METHODS: Searches of Medline, Scopus and Google Scholar for papers that analysed the subject of the study objective. The following MeSH descriptors were used: posture; postural balance; muscle, skeletal; task performance and analysis; back; and spine and music...
January 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/28166765/optitrain-a-randomised-controlled-exercise-trial-for-women-with-breast-cancer-undergoing-chemotherapy
#9
Y Wengström, K A Bolam, S Mijwel, C J Sundberg, M Backman, M Browall, J Norrbom, H Rundqvist
BACKGROUND: Women with breast cancer undergoing chemotherapy suffer from a range of detrimental disease and treatment related side-effects. Exercise has shown to be able to counter some of these side-effects and improve physical function as well as quality of life. The primary aim of the study is to investigate and compare the effects of two different exercise regimens on the primary outcome cancer-related fatigue and the secondary outcomes muscle strength, function and structure, cardiovascular fitness, systemic inflammation, skeletal muscle gene activity, health related quality of life, pain, disease and treatment-related symptoms in women with breast cancer receiving chemotherapy...
February 6, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28155812/human-muscle-precursor-cells-overexpressing-pgc-1%C3%AE-enhance-early-skeletal-muscle-tissue-formation
#10
Deana Haralampieva, Souzan Salemi, Ivana Dinulovic, Tullio Sulser, Simon M Ametamey, Christoph Handschin, Daniel Eberli
Muscle precursor cells (MPCs) are activated satellite cells capable of muscle fiber reconstruction. Therefore, autologous MPC transplantation is envisioned for the treatment of muscle diseases. However, the density of MPCs, as well as their proliferation and differentiation potential gradually decline with age. The goal of this research was to genetically modify human MPCs (hMPCs) to overexpress the peroxisome proliferator-activated receptor gamma coactivator (PGC-1α), a key regulator of exercise-mediated adaptation, and thereby to enhance early skeletal muscle formation and quality...
February 3, 2017: Cell Transplantation
https://www.readbyqxmd.com/read/28155183/sarcopenia-an-overview
#11
Emanuele Marzetti, Riccardo Calvani, Matteo Tosato, Matteo Cesari, Mauro Di Bari, Antonio Cherubini, Agnese Collamati, Emanuela D'Angelo, Marco Pahor, Roberto Bernabei, Francesco Landi
Sarcopenia, the age-dependent loss of muscle mass and function, is a common condition among older adults, and is associated with several adverse health outcomes. Owing to the impact of sarcopenia on quality of life, disability and mortality, a greater awareness is necessary in order to correctly identify the condition both in community and geriatric settings. Research on sarcopenia prevention and treatment is developing quickly, but many questions are still unanswered. The core of the sarcopenia condition involves quantitative and qualitative losses of skeletal muscle...
February 2, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28155179/the-need-of-operational-paradigms-for-frailty-in-older-persons-the-sprintt-project
#12
Matteo Cesari, Emanuele Marzetti, Riccardo Calvani, Bruno Vellas, Roberto Bernabei, Philippe Bordes, Ronenn Roubenoff, Francesco Landi, Antonio Cherubini
The exploration of frailty as a pre-disability geriatric condition represents one of the most promising research arenas of modern medicine. Frailty is today indicated as a paradigmatic condition around which the traditional healthcare systems might be re-shaped and optimized in order to address the complexities and peculiarities of elders. Unfortunately, the lack of consensus around a single operational definition has limited the clinical implementation of frailty in clinical practice. In these last years, growing attention (even beyond the traditional boundaries of geriatric medicine) has been given to physical performance measures...
February 2, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28150539/current-best-practice-in-rehabilitation-in-interstitial-lung-disease
#13
Atsuhito Nakazawa, Narelle S Cox, Anne E Holland
Interstitial lung disease (ILD) is a group of chronic respiratory diseases characterized by dyspnoea on exertion and decline in health-related quality of life (HRQL). People with ILD experience significant exercise limitation with contributors that include ventilatory limitation, impaired gas exchange, decreased cardiac function and skeletal muscle dysfunction. Pulmonary rehabilitation (PR) is well established in patients with chronic obstructive pulmonary disease (COPD) as a means to overcome exercise limitation and improve activity-related dyspnoea...
February 2017: Therapeutic Advances in Respiratory Disease
https://www.readbyqxmd.com/read/28143855/-nutraceuticals-in-relation-to-human-skeletal-muscle-and-exercise
#14
Colleen Siobhan Deane, Daniel J Wilkinson, Bethan E Phillips, Kenneth Smith, Timothy Etheridge, Philip J Atherton
Skeletal muscles have a fundamental role in locomotion and whole body metabolism, with muscle mass and quality being linked to improved health and even lifespan. Optimising nutrition in combination with exercise is considered an established, effective ergogenic practice for athletic performance. Importantly, exercise and nutritional approaches also remain arguably the most effective countermeasure for muscle dysfunction associated with ageing and numerous clinical conditions e.g. cancer cachexia, COPD and organ failure, via engendering favourable adaptations such as increased muscle mass and oxidative capacity...
January 31, 2017: American Journal of Physiology. Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28138227/electromyographic-activity-of-masticatory-muscles-in-elderly-women-a-pilot-study
#15
Ewelina Gaszynska, Karolina Kopacz, Magdalena Fronczek-Wojciechowska, Gianluca Padula, Franciszek Szatko
OBJECTIVES: To evaluate the effect of age and chosen factors related to aging such as dentition, muscle strength, and nutrition on masticatory muscles electromyographic activity during chewing in healthy elderly women. BACKGROUND: With longer lifespan there is a need for maintaining optimal quality of life and health in older age. Skeletal muscle strength deteriorates in older age. This deterioration is also observed within masticatory muscles. METHODS: A total of 30 women, aged 68-92 years, were included in the study: 10 individuals had natural functional dentition, 10 were missing posterior teeth in the upper and lower jaw reconstructed with removable partial dentures, and 10 were edontoulous, using complete removable dentures...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28119837/comparison-of-balance-proprioception-and-skeletal-muscle-mass-in-total-hip-replacement-patients-with-and-without-fracture-a-pilot-study
#16
Seunghwi Jo, Si-Bog Park, Mi Jung Kim, Taikon Kim, Kyeong Il Park, Junhyun Sung, Un Jin Park, Yee Suk Kim, Byeong Jik Kang, Kyu Hoon Lee
OBJECTIVE: To determine whether there was a difference in balance, proprioception, and skeletal muscle mass among patients who undergo hip fracture surgery relative to and elective total hip replacement (THR). METHODS: Thirty-one THR patients were enrolled. The patients were categorized into two groups: fracture group (n=15) and non-fracture group (n=16). Berg Balance Scale (BBS) was used to balance the proprioception of the hip joint while a joint position sense (JPS) test was used to evaluate it...
December 2016: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28115977/efficacy-of-a-novel-formulation-of-l-carnitine-creatine-and-leucine-on-lean-body-mass-and-functional-muscle-strength-in-healthy-older-adults-a-randomized-double-blind-placebo-controlled-study
#17
Malkanthi Evans, Najla Guthrie, John Pezzullo, Toran Sanli, Roger A Fielding, Aouatef Bellamine
BACKGROUND: Progressive decline in skeletal muscle mass and function are growing concerns in an aging population. Diet and physical activity are important for muscle maintenance but these requirements are not always met. This highlights the potential for nutritional supplementation. As a primary objective, we sought to assess the effect of a novel combination of L-Carnitine, creatine and leucine on muscle mass and performance in older subjects. METHOD: Forty-two healthy older adults aged 55-70 years were randomized to receive either a novel L-Carnitine (1500 mg), L-leucine (2000 mg), creatine (3000 mg), Vitamin D3 (10 μg) (L-Carnitine-combination) product (n = 14), L-Carnitine (1500 mg) (n = 14), or a placebo (n = 14) for eight weeks...
2017: Nutrition & Metabolism
https://www.readbyqxmd.com/read/28114110/effects-of-tissue-mechanical-and-acoustic-anisotropies-on-the-performance-of-a-cross-correlation-based-ultrasound-strain-imaging-method
#18
He Li, Wei-Ning Lee
The anisotropic mechanical properties (mechanical anisotropy) and view-dependent ultrasonic backscattering (acoustic anisotropy) of striated muscle due to the underlying myofiber arrangement have been well documented, but whether they impact on ultrasound strain imaging (USI) techniques remains unclear. The aim of this study was therefore to investigate the performance of a cross-correlation-based two-dimensional (2D) USI method in anisotropic media under controlled quasi-static compression in silico and in vitro...
February 21, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28110688/intradialytic-creatine-supplementation-a-scientific-rationale-for-improving-the-health-and-quality-of-life-of-dialysis-patients
#19
Theo Wallimann, Uwe Riek, Michael Möddel
The CK/PCr-system, with creatine (Cr) as an energy precursor, plays a crucial role in cellular physiology. In the kidney, as in other organs and cells with high and fluctuating energy requirements, energy-charged phospho-creatine (PCr) acts as an immediate high-energy source and energy buffer, and as an intracellular energy transport vehicle. A maximally filled total Cr (Cr plus PCr) pool is a prerequisite for optimal functioning of the body and its organs, and health. Skeletal- and cardiac muscles of dialysis patients with chronic kidney disease (CKD) are depleted of Cr in parallel with the duration of dialysis...
February 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28109186/interleukin-1-as-a-mediator-of-fatigue-in-disease-a-narrative-review
#20
REVIEW
Megan E Roerink, Marieke E van der Schaaf, Charles A Dinarello, Hans Knoop, Jos W M van der Meer
Fatigue is commonly reported in a variety of illnesses, and it has major impact on quality of life. Previously, it was thought that fatigue originates in the skeletal muscles, leading to cessation of activity. However, more recently, it has become clear that the brain is the central regulator of fatigue perception. It has been suggested that pro-inflammatory cytokines, especially interleukin-1 alpha (IL-1α) and interleukin-1 beta (IL-1β), play a prominent role in the development of central fatigue, and several studies have been performed to elucidate the connection between inflammation and these central processes...
January 21, 2017: Journal of Neuroinflammation
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