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Kazuki Okura, Atsuyoshi Kawagoshi, Masahiro Iwakura, Keiyu Sugawara, Hitomi Takahashi, Takeshi Kashiwagura, Mitsunobu Homma, Masahiro Satake, Takanobu Shioya
BACKGROUND AND OBJECTIVE: Diaphragm function might be useful to predict nocturnal oxygen desaturation in COPD. Ultrasonography has been widely used for the assessment of the diaphragm. We aimed to investigate the relationship between the contractile capability of the diaphragm assessed by ultrasonography and the nocturnal percutaneous arterial oxygen saturation (NSpO2 ) in COPD. METHODS: Twenty-eight male patients with COPD (age, 73 ± 7 years; forced expiratory volume in 1 s (FEV1 ), 54...
September 9, 2016: Respirology: Official Journal of the Asian Pacific Society of Respirology
Anja M Raab, Jörg Krebs, Claudio Perret, Franz Michel, Maria Te Hopman, Gabi Mueller
BACKGROUND: Respiratory complications remain a major cause of mortality among individuals with spinal-cord injury (SCI). The present study investigated whether respiratory function is a discriminator of pneumonia in individuals with SCI and is aimed to determine the best predictive parameter. METHODS: This was a retrospective cohort study. Individuals with traumatic SCI, level C3 to T12, complete and incomplete lesions, were included. Data on respiratory function were extracted from medical records...
August 30, 2016: Respiratory Care
Cássia Da Luz Goulart, Julio Cristiano Simon, Paloma De Borba Schneiders, Elisabete Antunes San Martin, Ramona Cabiddu, Audrey Borghi-Silva, Renata Trimer, Andréa Lúcia Gonçalves da Silva
INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is recognized as a multisystemic inflammatory disease associated with extrapulmonary comorbidities, including respiratory muscle weakness and cardiovascular and cardiac autonomic regulation disorders. We investigated whether alterations in respiratory muscle strength (RMS) would affect cardiac autonomic modulation in COPD patients. METHODS: This study was a cross-sectional study done in ten COPD patients affected by moderate to very severe disease...
2016: International Journal of Chronic Obstructive Pulmonary Disease
S Walterspacher, A Kirchberger, J Lambeck, D J Walker, A Schwörer, W D Niesen, W Windisch, F Hamzei, H J Kabitz
PURPOSE: Guillain-Barré Syndrome (GBS) is a life-threatening disease due to respiratory muscle involvement. This study aimed at objectively assessing the course of respiratory muscle function in GBS subjects within the first week of admission to an intensive care unit. METHODS: Medical Research Council Sum Score (MRC-SS), vigorimetry, spirometry, and respiratory muscle function tests (inspiratory/expiratory muscle strength: PImax/PEmax, sniff nasal pressure: SnPna) were assessed twice daily...
October 2016: Lung
Joshua R Smith, Ryan M Broxterman, Shane M Hammer, Andrew M Alexander, Kaylin D Didier, Stephanie P Kurti, Thomas J Barstow, Craig A Harms
It is currently unknown whether sex differences exist in the cardiovascular consequences of the inspiratory muscle metaboreflex. We hypothesized that the activation of the inspiratory muscle metaboreflex will lead to less of an increase in mean arterial pressure (MAP) and limb vascular resistance (LVR) and less of a decrease in limb blood flow (Q̇L) in women compared with men. Twenty healthy men (n = 10, 23 ± 2 yr) and women (n = 10, 22 ± 3 yr) were recruited for this study. Subjects performed inspiratory resistive breathing tasks (IRBTs) at 2% or 65% of their maximal inspiratory mouth pressure (PIMAX)...
September 1, 2016: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
Ioannis D Laoutaris, Stamatis Adamopoulos, Athanassios Manginas, Demosthenes B Panagiotakos, Dennis V Cokkinos, Athanasios Dritsas
BACKGROUND: We hypothesized that the ability to sustain maximal inspiratory pressure (SPImax) over time as a measure of work capacity may be more severely affected than inspiratory muscle strength (PImax) in patients with heart failure (HF). METHODS: We retrospectively investigated eighty patients with HF, NYHA II/III/ ambulatoryIV and a (mean±SD) LVEF 27±8%, and compared them to 25 healthy subjects (HS). During a maximal inspiratory manoeuvre from residual volume (RV) to total lung capacity, PImax was measured as the maximum mouth pressure at RV, inspiratory contraction time (ICT) as the time from RV to end of inspiration and SPImax as the area under a pressure-time curve using an electronic pressure manometer with designed-purpose software (Trainair(®), Project Electronics Ltd...
October 15, 2016: International Journal of Cardiology
Aikaterini Flevari, Michael Lignos, Dimitrios Konstantonis, Apostolos Armaganidis
BACKGROUNG: Diaphagmatic ultrasonography has been recently considered as a new weaning predictor method. Previous studies checked diaphragmatic excursion and thickness during quiet or deep breathing in unselected populations of critically ill patients. Our study aims to investigate diaphragmatic excursion during quiet and unassisted breathing, in comparison to standard predictor tools, such as Rapid Shallow Breathing Index (RSBI) and Maximal Inspiratory Pressure (Pimax), in patients with difficult and/ or prolonged weaning...
July 12, 2016: Minerva Anestesiologica
Mark Faghy, Sam Blacker, Peter I Brown
PURPOSE: The purpose of this study was to investigate whether loads carried in a backpack, with a load mass ranging from 0 to 20 kg, causes respiratory muscle fatigue. METHODS: Eight males performed four randomised load carriage (LC) trials comprising 60 min walking at 6.5 km h(-1) wearing a backpack of either 0 (LC0), 10 (LC10), 15 (LC15) or 20 kg (LC20). Inspiratory (PImax) and expiratory (PEmax) mouth pressures were assessed prior to and immediately following each trial...
November 2016: European Journal of Sport Science
Serina J McEntire, Joshua R Smith, Christine S Ferguson, Kelly R Brown, Stephanie P Kurti, Craig A Harms
The purpose was to determine the effect of moderate-intensity exercise training (ET) on inspiratory muscle fatigue (IMF) and if an additional inspiratory load during ET (ET+IL) would further improve inspiratory muscle strength, IMF, and time-trial performance. 15 subjects were randomly divided to ET (n=8) and ET+IL groups (n=7). All subjects completed six weeks of exercise training three days/week at ∼70%V̇O2peak for 30min. The ET+IL group breathed through an inspiratory muscle trainer (15% PImax) during exercise...
August 2016: Respiratory Physiology & Neurobiology
Jesús Sancho, Enric Bures, Saray de La Asunción, Emilio Servera
BACKGROUND: Mechanically assisted coughing with mechanical in-exsufflation (MI-E) is recommended for noninvasive management of respiratory secretions in amyotrophic lateral sclerosis (ALS). To improve the effectiveness of the technique, a new device combining MI-E with high-frequency oscillations (HFO) has been developed. This work aimed to assess the effect of HFO on the cough peak flow generated by MI-E in medically stable subjects with ALS. METHODS: This was a prospective study that included subjects with ALS in a medically stable condition...
August 2016: Respiratory Care
Bárbara Maria Hermes, Dannuey Machado Cardoso, Tiago José Nardi Gomes, Tamires Daros dos Santos, Marília Severo Vicente, Sérgio Nunes Pereira, Viviane Acunha Barbosa, Isabella Martins de Albuquerque
OBJECTIVE: To investigate the efficiency of short-term inspiratory muscle training program associated with combined aerobic and resistance exercise on respiratory muscle strength, functional capacity and quality of life in patients who underwent coronary artery bypass and are in the phase II cardiac rehabilitation program. METHODS: A prospective, quasi-experimental study with 24 patients who underwent coronary artery bypass and were randomly assigned to two groups in the Phase II cardiac rehabilitation program: inspiratory muscle training program associated with combined training (aerobic and resistance) group (GCR + IMT, n=12) and combined training with respiratory exercises group (GCR, n=12), over a period of 12 weeks, with two sessions per week...
July 2015: Revista Brasileira de Cirurgia Cardiovascular
Ioannis D Efstathiou, Irini P Mavrou, Konstantinos E Grigoriadis
BACKGROUND: This study aimed to examine the relationship between hand-grip force and maximum inspiratory pressure (PImax) in healthy young and middle-age individuals. METHODS: All individuals underwent assessment of inspiratory muscle strength by maximum inspiratory pressure using a U-type water manometer and evaluation of hand-grip force by a hydraulic hand dynamometer. RESULTS: The correlation of PImax and hand-grip force was strong (r = 0...
July 2016: Respiratory Care
Yoshihiro Yamashina, Hisayo Yokoyama, Nooshin Naghavi, Yoshikazu Hirasawa, Ryosuke Takeda, Akemi Ota, Daiki Imai, Toshiaki Miyagawa, Kazunobu Okazaki
[Purpose] The purpose of the present study was to evaluate the effect of water immersion at different water depths on respiratory function and the effect of inspiratory load breathing (ILB) during water immersion at different water depths on respiratory muscle strength evaluated by maximum inspiratory and expiratory pressures (PImax and PEmax, respectively). [Subjects] Eight healthy men participated randomly in three trials. [Methods] All sessions were conducted with the participants in a sitting position immersed in a water bath...
January 2016: Journal of Physical Therapy Science
Gerald S Supinski, Phillip Westgate, Leigh A Callahan
BACKGROUND: Respiratory muscle weakness contributes to respiratory failure in ICU patients. Unfortunately, assessment of weakness is difficult since the most objective test, transdiaphragmatic pressure in response to phrenic nerve stimulation (PdiTw), is difficult to perform. While most clinicians utilize maximum inspiratory pressure (Pimax) to assess strength, the relationship of this index to PdiTw has not been evaluated in a large ICU population. The purpose of the present study was to assess both PdiTw and Pimax in ICU patients to determine how these indices correlate with each other, what factors influence these indices, and how well these indices predict outcomes...
2016: Critical Care: the Official Journal of the Critical Care Forum
B Wirth, T Duarte Ferreira, M Mittelholzer, B K Humphreys, U Boutellier
BACKGROUND: Patients with chronic neck pain show also respiratory dysfunctions. OBJECTIVE: To investigate the effects of respiratory muscle endurance training (RMET) on chronic neck pain. METHODS: In this pilot study (single-subject design: 3 baseline measurements, 4 measurements during RMET), 15 neck patients (49.3 ± 13.7 years; 13 females) conducted 20 sessions of home-based RMET using a SpiroTiger® (normocapnic hyperpnoea). Maximal voluntary ventilation (MVV), maximal inspiratory (Pimax) and expiratory (Pemax) pressure were measured before and after RMET...
March 18, 2016: Journal of Back and Musculoskeletal Rehabilitation
Mehdi Chlif, David Keochkerian, Abdou Temfemo, Dominique Choquet, Said Ahmaidi
The aim of this study was to compare the inspiratory muscle performance during an incremental exercise of twelve fit old endurance-trained athletes (OT) with that of fit young athletes (YT) and healthy age-matched controls (OC). The tension-time index (TT0.1) was determined according to the equation TT0.1=P0.1/PImax×ti/ttot, where P0.1 is the mouth occlusion pressure, PImax the maximal inspiratory pressure and ti/ttot the duty cycle. For a given VCO2, OT group displayed P0.1, P0.1/PImax ratio, TT0.1 and effective impedance of the respiratory muscle values which were lower than OC group and higher than YT group...
July 2016: Respiratory Physiology & Neurobiology
Prem Balaguru, Vishnupriya Hariharan, Rajajeyakumar Manivel, Madanmohan Trakroo
INTRODUCTION: Health care economics restricts many health centers from using hi-tech diagnostics equipment. Mercury manometers are used for calibration of pressure transducers. If standardized it would be a cost effective, simple alternative to transducers in low economic settings. AIM: To analyse the feasibility of mercury manometer usage in respiratory pressure measurement. MATERIALS AND METHODS: The experimental study was conducted with 30 healthy volunteers of age group 17-19 yrs...
January 2016: Journal of Clinical and Diagnostic Research: JCDR
Prashanth Bhat, Janet L Peacock, Gerrard F Rafferty, Simon Hannam, Anne Greenough
OBJECTIVE: The tension-time index of the diaphragm (TTdi) is a composite assessment of the load on and the capacity of the diaphragm. TTmus is a non-invasive tension-time index of the respiratory muscles. Our aim was to determine whether TTdi or TTmus predicted extubation outcome and performed better than respiratory muscle strength (Pimax, Pdimax), respiratory drive (P0.1) and work of breathing (transdiaphragmatic pressure-time product (PTPdi)) or routinely available clinical data. DESIGN: Prospective study...
September 2016: Archives of Disease in Childhood. Fetal and Neonatal Edition
Aso Schein, Aps Correa, Karina Rabello Casali, Beatriz D Schaan
BACKGROUND: Physical exercise reduces glucose levels and glucose variability in patients with type 2 diabetes. Acute inspiratory muscle exercise has been shown to reduce these parameters in a small group of patients with type 2 diabetes, but these results have yet to be confirmed in a well-designed study. The aim of this study is to investigate the effect of acute inspiratory muscle exercise on glucose levels, glucose variability, and cardiovascular autonomic function in patients with type 2 diabetes...
2016: Trials
Michał Majewski, Grażyna Dąbrowska, Malwina Pawik, Krystyna Rożek
BACKGROUND: Asthma is a disease that affects people of all ages worldwide. OBJECTIVES: The aim of the study was to evaluate the effectiveness of a home-based pulmonary rehabilitation program, with one supervised session a week, for improvement of respiratory function, inspiratory muscle strength and physical fitness in older women suffering from asthma. MATERIAL AND METHODS: The study involved 10 female patients (mean age 70.8) with diagnosed bronchial asthma in the slight and moderate stage...
November 2015: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
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