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https://www.readbyqxmd.com/read/28643572/distinctive-barriers-to-antiretroviral-therapy-adherence-among-non-adherent-adolescents-living-with-hiv-in-botswana
#1
Elizabeth Yang, Seipone Mphele, Neo Moshashane, Boineelo Bula, Jennifer Chapman, Harriet Okatch, Ed Pettitt, Ontibile Tshume, Tafireyi Marukutira, Gabriel Anabwani, Elizabeth Lowenthal
Levels of adherence to HIV treatment are lower among adolescents compared with older and younger individuals receiving similar therapies. We purposely sampled the most and least adherent adolescents from a 300-adolescent longitudinal HIV treatment adherence study in Gaborone, Botswana. Multiple objective and subjective measures of adherence were available and study participants were selected based on sustained patterns of either excellent or poor adherence over a one-year period. Focus group discussions (FGD) and in-depth interviews (IDI) were conducted with the adolescents and a subset of their caregivers with the goal of revealing barriers and facilitators of adherence...
June 23, 2017: AIDS Care
https://www.readbyqxmd.com/read/28642213/development-of-a-web-based-intervention-for-addressing-distress-in-caregivers-of-patients-receiving-stem-cell-transplants-formative-evaluation-with-stakeholder-interviews-and-focus-groups
#2
Nicole Amoyal Pensak, Tanisha Joshi, Teresa Simoneau, Kristin Kilbourn, Alaina Carr, Jean Kutner, Mark L Laudenslager
BACKGROUND: Caregivers of cancer patients experience significant burden and distress including depression and anxiety. We previously demonstrated the efficacy of an eight session, in-person, one-on-one stress management intervention to reduce distress in caregivers of patients receiving allogeneic hematopoietic stem cell transplants (allo-HSCT). OBJECTIVE: The objective of this study was to adapt and enhance the in-person caregiver stress management intervention to a mobilized website (eg, tablet, smartphone, or computer-based) for self-delivery in order to enhance dissemination to caregiver populations most in need...
June 22, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28640830/optimal-sequencing-strategies-for-identifying-disease-associated-singletons
#3
Sara Rashkin, Goo Jun, Sai Chen, Goncalo R Abecasis
With the increasing focus of genetic association on the identification of trait-associated rare variants through sequencing, it is important to identify the most cost-effective sequencing strategies for these studies. Deep sequencing will accurately detect and genotype the most rare variants per individual, but may limit sample size. Low pass sequencing will miss some variants in each individual but has been shown to provide a cost-effective alternative for studies of common variants. Here, we investigate the impact of sequencing depth on studies of rare variants, focusing on singletons-the variants that are sampled in a single individual and are hardest to detect at low sequencing depths...
June 22, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28639361/experiences-and-needs-of-relatives-of-people-with-dementia-in-acute-hospitals-a-meta-synthesis-of-qualitative-studies
#4
REVIEW
Melanie Burgstaller, Hanna Mayer, Cornel Schiess, Susi Saxer
AIMS AND OBJECTIVES: The purpose of this meta-synthesis was to present an in-depth analysis of existing qualitative literature concerning experiences and needs of the relatives of patients with dementia in hospitals. BACKGROUND: Relatives are an important resource for the care of patients with dementia in hospitals. They provide necessary information about the patient and can support the patient's care. Simultaneously, they are themselves vulnerable, having specific needs and experiences...
June 21, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28637262/qualitative-exploration-of-a-smoking-cessation-trial-for-people-living-with-hiv-in-south-africa
#5
Nandita Krishnan, Joel Gittelsohn, Alexandra Ross, Jessica Elf, Sandy Chon, Raymond Niaura, Neil Martinson, Jonathan E Golub
Introduction: In South Africa, people living with HIV (PLWH) have a high prevalence of smoking, which undermines the beneficial effects of antiretroviral therapy (ART). However, little is known about barriers to smoking cessation and what interventions work for PLWH in this setting. Methods: A randomized trial comparing intensive anti-smoking counseling versus counseling and nicotine replacement therapy (NRT) was recently concluded in Klerksdorp, South Africa. In a post-trial follow-up, 23 in-depth interviews with patients and one focus group discussion with counselors from the trial were conducted...
June 16, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28637191/value-added-strategy-models-to-provide-quality-services-in-senior-health-business
#6
Ya-Ting Yang, Neng-Pai Lin, Shyi Su, Ya-Mei Chen, Yao-Mao Chang, Yujiro Handa, Hafsah Arshed Ali Khan, Yi-Hsin Elsa Hsu
Objective: The rapid population aging is now a global issue. The increase in the elderly population will impact the health care industry and health enterprises; various senior needs will promote the growth of the senior health industry. Most senior health studies are focused on the demand side and scarcely on supply. Our study selected quality enterprises focused on aging health and analyzed different strategies to provide excellent quality services to senior health enterprises. Design: We selected 33 quality senior health enterprises in Taiwan and investigated their excellent quality services strategies by face-to-face semi-structured in-depth interviews with CEO and managers of each enterprise in 2013...
June 20, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28635409/confronting-infertility-in-iranian-clients-a-grounded-theory
#7
Mitra Zandi, Eesa Mohammadi, Zohreh Vanaki, Marziyeh Shiva, Narges Bagheri Lankarani, Faezeh Zarei
The present study examined how infertile Iranian clients confront infertility. Research on infertility has confirmed the significance of a socio-cultural context in the formation of responses to infertility. This study used the grounded theory approach to explore the experiences of infertile individuals presenting at the Royan Institute in Iran from October 2013 to September 2014. Clients with infertility of at least two years in duration were recruited using purposive sampling followed by theoretical sampling...
February 10, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28634910/the-complex-biology-of-the-aryl-hydrocarbon-receptor-and-its-role-in-the-pituitary-gland
#8
REVIEW
Robert Formosa, Josanne Vassallo
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor best known for its ability to mediate the effects of environmental toxins such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD or dioxin), polycyclic aromatic hydrocarbons (PAHs), benzene, and polychlorinated biphenyls (PCBs) through the initiation of transcription of a number of metabolically active enzymes. Therefore, the AHR has been studied mostly in the context of xenobiotic signaling. However, several studies have shown that the AHR is constitutively active and plays an important role in general cell physiology, independently of its activity as a xenobiotic receptor and in the absence of exogenous ligands...
June 20, 2017: Hormones & Cancer
https://www.readbyqxmd.com/read/28633131/dose-calculation-using-haar-wavelets-with-buildup-correction
#9
K Belkadhi, K Elhamdi, M Bhar, K Manai
In this work, we focus on the buildup correction of dose calculation using Haar wavelets in the Tunisian gamma irradiation facility. The buildup effect of gamma rays was used to adjust absorbed dose calculation for different depth in the irradiated products. A buildup study with different product densities was carried out to generalize the dose adjustment approach to any product at any depth.
June 15, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28631501/ambivalence-in-rehabilitation-thematic-analysis-of-the-experiences-of-lower-limb-amputated-veterans
#10
Jan Christensen, Henning Langberg, Patrick Doherty, Ingrid Egerod
BACKGROUND: Knowledge about the organization and factors of importance to rehabilitation of veterans with lower limb amputation is sparse. The aim of this study was, therefore, to improve understanding of the influences of "military identity" on the organization of rehabilitation services and to investigate those factors influential in achieving successful rehabilitation, including interprofessional collaboration between different sectors involved in the rehabilitation of veterans with lower limb amputations...
June 20, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28629475/can-formalizing-links-among-community-health-workers-accredited-drug-dispensing-outlet-dispensers-and-health-facility-staff-increase-their-collaboration-to-improve-prompt-access-to-maternal-and-child-care-a-qualitative-study-in-tanzania
#11
Angel Dillip, Suleiman Kimatta, Martha Embrey, John C Chalker, Richard Valimba, Mariam Malliwah, John Meena, Rachel Lieber, Keith Johnson
BACKGROUND: In Tanzania, progress toward achieving the 2015 Millennium Development Goals for maternal and newborn health was slow. An intervention brought together community health workers, health facility staff, and accredited drug dispensing outlet (ADDO) dispensers to improve maternal and newborn health through a mechanism of collaboration and referral. This study explored barriers, successes, and promising approaches to increasing timely access to care by linking the three levels of health care provision...
June 19, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28629471/improving-child-nutrition-and-development-through-community-based-childcare-centres-in-malawi-the-neep-ie-study-study-protocol-for-a-randomised-controlled-trial
#12
Aulo Gelli, Amy Margolies, Marco Santacroce, Katie Sproule, Sophie Theis, Natalie Roschnik, Aisha Twalibu, George Chidalengwa, Amrik Cooper, Tyler Moorhead, Melissa Gladstone, Patricia Kariger, Mangani Kutundu
BACKGROUND: The Nutrition Embedded Evaluation Programme Impact Evaluation (NEEP-IE) study is a cluster randomised controlled trial designed to evaluate the impact of a childcare centre-based integrated nutritional and agricultural intervention on the diets, nutrition and development of young children in Malawi. The intervention includes activities to improve nutritious food production and training/behaviour-change communication to improve food intake, care and hygiene practices. This paper presents the rationale and study design for this randomised control trial...
June 19, 2017: Trials
https://www.readbyqxmd.com/read/28629360/conceptualisation-of-job-related-wellbeing-stress-and-burnout-among-healthcare-workers-in-rural-ethiopia-a-qualitative-study
#13
Medhin Selamu, Graham Thornicroft, Abebaw Fekadu, Charlotte Hanlon
BACKGROUND: Wellbeing of healthcare workers is important for the effective functioning of health systems. The aim of this study was to explore the conceptualisations of wellbeing, stress and burnout among healthcare workers in primary healthcare settings in rural Ethiopia in order to inform the development of contextually appropriate interventions. METHODS: A qualitative study was conducted in a rural zone of southern Ethiopia. A total of 52 frontline primary healthcare workers participated in in-depth interviews (n = 18) or Focus Group Discussions (FGDs) (4 groups, total n = 34)...
June 19, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28627938/-i-ve-got-somebody-there-someone-cares-what-support-is-most-valued-following-a-stroke
#14
Sarah Northcott, Katerina Hilari
PURPOSE: There is often a need for increased support following a stroke. This study explored what types of support are provided by different network members and what support functions are most valued. METHODS: Adults with first stroke were recruited from a stroke unit and participated in in-depth interviews 8-15 months poststroke. Framework Analysis was used to build thematic and explanatory accounts of the data. RESULTS: Twenty-nine participants took part...
June 19, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28627331/dynamic-transmit-receive-beamforming-by-spatial-matched-filtering-for-ultrasound-imaging-with-plane-wave-transmission
#15
Yuling Chen, Yang Lou, Jesse Yen
During conventional ultrasound imaging, the need for multiple transmissions for one image and the time of flight for a desired imaging depth limit the frame rate of the system. Using a single plane wave pulse during each transmission followed by parallel receive processing allows for high frame rate imaging. However, image quality is degraded because of the lack of transmit focusing. Beamforming by spatial matched filtering (SMF) is a promising method which focuses ultrasonic energy using spatial filters constructed from the transmit-receive impulse response of the system...
July 2017: Ultrasonic Imaging
https://www.readbyqxmd.com/read/28627261/maternal-psychological-distress-and-perceived-impact-on-child-feeding-practices-in-south-kivu-dr-congo
#16
Jillian A Emerson, Wietse Tol, Laura E Caulfield, Shannon Doocy
BACKGROUND: Maternal mental health problems are associated with poor child growth and suboptimal child feeding practices, yet little qualitative research has been conducted to understand mothers' perceptions about how maternal mental ill health and child nutrition are related. OBJECTIVE: The objective of the study was to understand maternal perceptions on sources of psychological distress, and how distress impacts functioning, especially related to childcare and feeding practices among mothers of young children in South Kivu, DR Congo...
January 1, 2017: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/28626598/design-concerns-of-room-and-pillar-retreat-panels
#17
Ted M Klemetti, Morgan M Sears, Ihsan B Tulu
Why do some room and pillar retreat panels encounter abnormal conditions? What factors deserve the most consideration during the planning and execution phases of mining and what can be done to mitigate those abnormal conditions when they are encountered? To help answer these questions, and to determine some of the relevant factors influencing the conditions of room and pillar (R & P) retreat mining entries, four consecutive R & P retreat panels were evaluated. This evaluation was intended to reinforce the influence of topographic changes, depth of cover, multiple-seam interactions, geological conditions, and mining geometry...
January 2017: International Journal of Mining Science and Technology
https://www.readbyqxmd.com/read/28624539/polarization-resolved-second-harmonic-microscopy
#18
REVIEW
Nirmal Mazumder, Gitanjal Deka, Wei-Wen Wu, Ankur Gogoi, Guan-Yu Zhuo, Fu-Jen Kao
Second harmonic (SH) microscopy has proven to be a powerful imaging modality over the past years due to its intrinsic advantages as a multiphoton process with endogenous contrast specificity, which allows pinhole-less optical sectioning, non-invasive observation, deep tissue penetration, and the possibility of easier signal detection at visible wavelengths. Depending on the relative orientation between the polarization of the incoming light and the second-order susceptibility of non-centrosymmetric structures, SH microscopy provides the unique capacity to probe the absolute molecular structure of a broad variety of biological tissues without the necessity for additional labeling...
June 14, 2017: Methods: a Companion to Methods in Enzymology
https://www.readbyqxmd.com/read/28623369/looking-beyond-the-imaging-plane-3d-needle-tracking-with-a-linear-array-ultrasound-probe
#19
Wenfeng Xia, Simeon J West, Malcolm C Finlay, Jean-Martial Mari, Sebastien Ourselin, Anna L David, Adrien E Desjardins
Ultrasound is well suited for guiding many minimally invasive procedures, but its use is often precluded by the poor visibility of medical devices. When devices are not visible, they can damage critical structures, with life-threatening complications. Here, we developed the first ultrasound probe that comprises both focused and unfocused transducer elements to provide both 2D B-mode ultrasound imaging and 3D ultrasonic needle tracking. A fibre-optic hydrophone was integrated into a needle to receive Golay-coded transmissions from the probe and these data were processed to obtain tracking images of the needle tip...
June 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28623053/lgbt-healthcare-disparities-what-progress-have-we-made
#20
Kathleen A Bonvicini
Nearly fifteen years have passed since this author's publication which examined the depth of education and training for medical students and practicing physicians specific to clinical competence in the care of lesbian and gay patients in the United States. Since then, there has been an explosion of research gains which have shed a steady light on the needs and disparities of lesbian and gay healthcare. This rich literature base has expanded to include bisexual and transgender (LGBT) healthcare in peer-reviewed journals...
June 10, 2017: Patient Education and Counseling
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