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https://www.readbyqxmd.com/read/28329804/-i-feel-trapped-the-tension-between-personal-and-structural-factors-of-social-isolation-and-the-desire-for-social-integration-among-older-residents-of-a-high-crime-neighborhood
#1
Elena Portacolone, Carla Perissinotto, Jarmin Christine Yeh, S Ryan Greysen
Background and Objectives: The aim of this study was to examine the factors contributing to the social isolation of older residents of a high-crime neighborhood through the in-depth examination of their lived experiences. A deeper understanding of factors contributing to social isolation can allow policymakers and health care providers to create policies and programs to alleviate the social isolation of these vulnerable and understudied individuals. Research Design and Methods: Participants were recruited through the support of the Housing Authority and Police and Fire Departments of Richmond, California, a town with a high-crime rate...
February 17, 2017: Gerontologist
https://www.readbyqxmd.com/read/28327160/what-constitutes-problematic-khat-use-an-exploratory-mixed-methods-study-in-ethiopia
#2
Awoke Mihretu, Solomon Teferra, Abebaw Fekadu
BACKGROUND: Khat is a psycho-stimulant herb, which has been in use in traditional societies in East Africa and the Middle East over many centuries. Although khat is reported to cause various health problems, what constitutes problematic khat use has never been systematically investigated. This study explored the acceptable and problematic uses of khat from the perspective of users. METHODS: The study used a mixed methods design (exploratory sequential) in which qualitative (emic) data were collected to develop a framework to define problematic khat use...
March 21, 2017: Substance Abuse Treatment, Prevention, and Policy
https://www.readbyqxmd.com/read/28327157/factors-influencing-implementation-of-a-patient-decision-aid-in-a-developing-country-an-exploratory-study
#3
Wen Ting Tong, Yew Kong Lee, Chirk Jenn Ng, Ping Yein Lee
BACKGROUND: Most studies on barriers and facilitators to implementation of patient decision aids (PDAs) are conducted in the west; hence, the findings may not be transferable to developing countries. This study aims to use a locally developed insulin PDA as an exemplar to explore the barriers and facilitators to implementing PDAs in Malaysia, an upper middle-income country in Asia. METHODS: Qualitative methodology was adopted. Nine in-depth interviews (IDIs) and three focus group discussions (FGDs) were conducted with policymakers (n = 6), medical officers (n = 13), diabetes educators (n = 5) and a nurse, who were involved in insulin initiation management at an academic primary care clinic...
March 21, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28327136/perceptions-of-interprofessional-collaboration-of-general-practitioners-and-community-pharmacists-a-qualitative-study
#4
Christin Löffler, Carolin Koudmani, Femke Böhmer, Susanne D Paschka, Jennifer Höck, Eva Drewelow, Martin Stremme, Bernd Stahlhacke, Attila Altiner
BACKGROUND: Despite numerous evidences for the positive effect of community pharmacists on health care, interprofessional collaboration of pharmacists and general practitioners is very often limited. Though highly trained, pharmacists remain an underutilised resource in primary health care in most western countries. This qualitative study aims at investigating pharmacists' and general practitioners' views on barriers to interprofessional collaboration in the German health care system...
March 21, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28326915/routledge-handbook-on-the-global-history-of-nursing-d-antonio-patricia-fairman-julie-whelan-jean-c-routledge-handbook-on-the-global-history-of-nursing-270pp-%C3%A2-39-99-routledge-9781138958982-1138958980-formula-see-text
#5
(no author information available yet)
The chapters in this book vary in the depth, nature and quality of historical research they represent, but all are interesting and worth reading. Some focus on particular methods and others focus on various historical topics.
March 22, 2017: Nurse Researcher
https://www.readbyqxmd.com/read/28326607/effect-of-apparent-depth-cues-on-accommodation-in-a-badal-optometer
#6
Carles Otero, Mikel Aldaba, Beatriz Martínez-Navarro, Jaume Pujol
BACKGROUND: The aim was to analyse the effect of peripheral depth cues on accommodation in Badal optometers. METHODS: Monocular refractions at 0.17 and 5.00 D of accommodative stimulus were measured with the PowerRef II autorefractor (Plusoptix Inc., Atlanta, Georgia, USA). Subjects looked (randomly) at four different scenes, one real scene comprising familiar objects at different depth planes (Real) and three virtual scenes comprising different two-dimensional pictures seen through a Badal lens...
March 21, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28325543/consensus-recommendations-on-exploring-effective-solutions-for-the-rising-cost-of-diabetes
#7
REVIEW
Shaukat M Sadikot, Ashok Kumar Das, John Wilding, Ali Siyan, Abdul Hamid Zargar, Banshi Saboo, S R Aravind, Bhavana Sosale, Sanjay Kalra, G Vijayakumar, K K Manojan, Anuj Maheshwari, Jayant K Panda, Samar Banerjee, Rajeev Chawla, Sambu Potty Vasudevan, O S Syam Sundar, Jothydev Kesavadev
Diabetes remains asymptomatic for a long period of time and its real burden gets noticed only once the complications set in. The number of individuals affected with the disease is also on the rise and more so in the low income countries. This scenario calls for urgent precautionary measures that need to be undertaken to equip ourselves to fight against this chronic disease. Individuals with financial constraints cannot afford to access even the basic treatment facilities and thus stands the most burdened. The International Diabetes Federation calls for 'Eyes on Diabetes' for the society to focus on early screening and early intervention...
March 7, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28323754/-it-s-inside-my-body-and-it-s-mine
#8
Elizabeth T Montgomery, Ariane van der Straten, Miria Chitukuta, Krishnaveni Reddy, Kubashni Woeber, Millicent Atujuna, Linda-Gail Bekker, Juliane Etima, Teopista Nakyanzi, Ashley J Mayo, Ariana Katz, Nicole Laborde, Cynthia I Grossman, Lydia Soto-Torres, Thesla Palanee-Phillips, Jared M Baeten
The MTN-020/ASPIRE trial evaluated the safety and effectiveness of the dapivirine vaginal ring for prevention of HIV-1 infection among African women. A nested qualitative component was conducted at 6 of 15 study sites in Uganda, Malawi, Zimbabwe and South Africa to evaluate acceptability of and adherence to the ring. Qualitative study participants (n = 214) were interviewed with one of 3 modalities: single in-depth interview, up to 3 serial interviews, or an exit Focus Group Discussion. Using semi-structured guides administered in local languages, 280 interviews were audio-recorded, transcribed, translated, coded and analyzed...
March 18, 2017: AIDS
https://www.readbyqxmd.com/read/28323638/fast-lesion-mapping-during-hifu-treatment-using-harmonic-motion-imaging-guided-focused-ultrasound-hmigfus-in-vitro-and-in-vivo
#9
Yang Han, Shutao Wang, Thomas Payen, Elisa Konofagou
The successful clinical application of high intensity focused ultrasound (HIFU) ablation depends on reliable monitoring of the lesion formation. Harmonic motion imaging guided focused ultrasound (HMIgFUS) is an ultrasound-based elasticity imaging technique, which monitors HIFU ablation based on the stiffness change of the tissue instead of the echo intensity change in conventional B-mode monitoring, rendering it potentially more sensitive to lesion development. Our group has shown that predicting the lesion location based on the radiation force-excited region is feasible during HMIgFUS...
March 21, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28322153/recent-progress-in-808-nm-excited-upconversion-nanomaterials-as-multifunctional-nanoprobes-for-visualized-theranostics-in-cancers
#10
Leyong Zeng, Di Wu, Ying Tian, Yuanwei Pan, Aiguo Wu, Jinchao Zhang, Guangming Lu
Near-infrared (NIR) light responsive nanomaterials have attracted considerable attention due to their location in the biological window. Especially, lanthanide-doped nanomaterials exhibit unique upconversion luminescence (UCL) properties with low background interference and long luminescence lifetime, which makes them promising in imaging diagnosis of cancers. Compared with traditional upconversion nanomaterials excited by 980 nm laser, 808 nm excitation can overcome the disadvantages of high heating effect and weak penetration depth induced by excitation source...
March 20, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28320664/blind-forensics-of-successive-geometric-transformations-in-digital-images-using-spectral-method-theory-and-applications
#11
Jiangqun Ni, Chenglong Chen, Zhaoyi Shen, Yun-Qing Shi
Geometric transformations, such as resizing and rotation, are almost always needed when two or more images are spliced together to create convincing image forgeries. In recent years, researchers have developed many digital forensic techniques to identify these operations. Most previous works in this area focus on the analysis of images that have undergone single geometric transformations, e.g., resizing or rotation. In several recent works, researchers have addressed yet another practical and realistic situation: successive geometric transformations, e...
March 15, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28320658/compressed-sensing-based-synthetic-transmit-aperture-imaging-validation-in-a-convex-array-configuration
#12
Jing Liu, Qiong He, Jianwen Luo
According to the linear acoustic theory, the channel data of a plane wave emitted by a linear array is a linear combination of the full dataset of synthetic transmit aperture (STA). Combining this relationship with compressed sensing (CS), a novel CS based ultrasound beamforming strategy, named compressed sensing based synthetic transmit aperture (CS-STA), was previously proposed to increase the frame rate of ultrasound imaging without sacrificing the image quality for a linear array. In this paper, assuming linear transfer function of pulse-echo ultrasound system, we derived and applied the theory of CS-STA for a slightly curved array and validated CS-STA in a convex array configuration...
March 14, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28320399/vasculogenic-mimicry-signaling-revisited-focus-on-non-vascular-ve-cadherin
#13
REVIEW
Daniel Delgado-Bellido, Santiago Serrano-Saenz, Mónica Fernández-Cortés, F Javier Oliver
Vasculogenic mimicry (VM) is a blood supply system independent of endothelial vessels in tumor cells from different origins. It reflects the plasticity of aggressive tumor cells that express vascular cell markers and line tumor vasculature. The presence of VM is associated with a high tumor grade, short survival, invasion and metastasis. Endothelial cells (ECs) express various members of the cadherin superfamily, in particular vascular endothelial (VE-) cadherin, which is the main adhesion receptor of endothelial adherent junctions...
March 21, 2017: Molecular Cancer
https://www.readbyqxmd.com/read/28317112/sacred-practices-and-family-processes-in-a-jewish-context-shabbat-as-the-weekly-family-ritual-par-excellence
#14
Loren D Marks, Trevan G Hatch, David C Dollahite
The present article provides a deep and more focused look at the utility, meaning, processes, and power involved in a specific, family-level, sacred practice or ritual from Judaism: Shabbat (Sabbath). Content analysis of in-depth interviews with 30 diverse, marriage-based Jewish families living in the United States (N = 77 individuals) yielded three emergent themes: (a) "Shabbat brings us closer together"; (b) How Shabbat brings the family together; and (c) The Power of Blessing the Children. These themes will be discussed respectively, along with related verbatim data from participants' in-depth qualitative interviews...
March 19, 2017: Family Process
https://www.readbyqxmd.com/read/28315115/interprofessional-communication-between-community-pharmacists-and-general-practitioners-a-qualitative-study
#15
Marina Weissenborn, Walter E Haefeli, Frank Peters-Klimm, Hanna M Seidling
Background While collaboration between community pharmacists (CPs) and general practitioners (GPs) is essential to provide comprehensive patient care, their communication often is scarce and hampered by multiple barriers. Objective We aimed to assess both professions' perceptions of interprofessional communication with regard to content and methods of communication as a basis to subsequently develop best-practice recommendations for information exchange. Setting Ambulatory care setting in Germany. Method CPs and GPs shared their experience in focus groups and in-depth interviews which were conducted using a semi-structured interview guideline...
March 17, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28306751/peptidomic-and-transcriptomic-profiling-of-four-distinct-spider-venoms
#16
Vera Oldrati, Dominique Koua, Pierre-Marie Allard, Nicolas Hulo, Miriam Arrell, Wolfgang Nentwig, Frédérique Lisacek, Jean-Luc Wolfender, Lucia Kuhn-Nentwig, Reto Stöcklin
Venom based research is exploited to find novel candidates for the development of innovative pharmacological tools, drug candidates and new ingredients for cosmetic and agrochemical industries. Moreover, venomics, as a well-established approach in systems biology, helps to elucidate the genetic mechanisms of the production of such a great molecular biodiversity. Today the advances made in the proteomics, transcriptomics and bioinformatics fields, favor venomics, allowing the in depth study of complex matrices and the elucidation even of minor compounds present in minute biological samples...
2017: PloS One
https://www.readbyqxmd.com/read/28306241/development-of-chemical-isotope-labeling-lc-ms-for-milk-metabolomics-comprehensive-and-quantitative-profiling-of-the-amine-phenol-submetabolome
#17
Dorothea Mung, Liang Li
Milk is a complex sample containing a variety of proteins, lipids and metabolites. Studying the milk metabolome represents an important application of metabolomics in the general area of nutritional research. However, comprehensive and quantitative analysis of milk metabolites is a challenging task due to the wide range of variations in chemical/physical properties and concentrations of these metabolites. We report an analytical workflow for in-depth profiling of the milk metabolome based on chemical isotope labeling (CIL) and liquid chromatography mass spectrometry (LC-MS) with a focus of using dansylation labeling to target the amine/phenol submetabolome...
March 17, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28303970/transient-desialylation-in-combination-with-a-novel-antithrombin-deficiency-causing-a-severe-and-recurrent-thrombosis-despite-anticoagulation-therapy
#18
Nuria Revilla, María Eugenia de la Morena-Barrio, Antonia Miñano, Raquel López-Gálvez, Mara Toderici, José Padilla, Ángel García-Avello, María Luisa Lozano, Dirk J Lefeber, Javier Corral, Vicente Vicente
An in-depth focused study of specific cases of patients with recurrent thrombosis may help to identify novel circumstances, genetic and acquired factors contributing to the development of this disorder. The aim of this study was to carry out a detailed and sequential analysis of samples from a patient suffering from early and recurrent venous and arterial thrombosis. We performed thrombophilic tests, biochemical, functional, genetic and glycomic analysis of antithrombin and other plasma proteins. The patient carried a new type I antithrombin mutation (p...
March 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28303666/is-the-methanogenic-community-reflecting-the-methane-emissions-of-river-sediments-comparison-of-two-study-sites
#19
Prem Prashant Chaudhary, Martin Rulík, Martin Blaser
Studies on methanogenesis from freshwater sediments have so far primarily focused on lake sediments. To expand our knowledge on the community composition of methanogenic archaea in river sediments, we studied the abundance and diversity of methanogenic archaea at two localities along a vertical profile (top 50 cm) obtained from sediment samples from Sitka stream (the Czech Republic). In this study, we compare two sites which previously have been shown to have a 10-fold different methane emission. Archaeal and methanogen abundance were analyzed by real-time PCR and T-RFLP...
March 16, 2017: MicrobiologyOpen
https://www.readbyqxmd.com/read/28302095/perceptions-of-community-based-field-workers-on-the-effect-of-a-longitudinal-biomedical-research-project-on-their-sustainable-livelihoods
#20
Christabelle S Moyo, Joseph Francis, Pascal O Bessong
BACKGROUND: Researchers involved in biomedical community-based projects rarely seek the perspectives of community fieldworkers, who are the 'foot soldiers' in such projects. Understanding the effect of biomedical research on community-based field workers could identify benefits and shortfalls that may be crucial to the success of community-based studies. The present study explored the perceptions of community-based field workers on the effect of the Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development Project" (MAL-ED) South Africa on their tangible and intangible capital which together comprise sustainable livelihoods...
March 17, 2017: BMC Public Health
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