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https://www.readbyqxmd.com/read/29783246/-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B1-%C3%B1-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B1-%C3%B1-%C3%B1-%C3%B0%C2%BA-%C3%B0-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B0-%C3%B1-%C3%B1-%C3%B1-%C3%B1-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0
#1
Nataliia O Rynhach, Vasyl M Mykhalchuk, Anatolii H Krut
OBJECTIVE: Introduction: This publication focuses on role of physical activity in promoting and protecting health and well-being. Physical activity is a significant risk factor for noncommunicable diseases. The public's awareness of the risk factors of non-communicable diseases is an important component of their control. The aim: To estimate the level of knowledge of the working age population regarding the essence of a healthy lifestyle and risk factors for non-communicable diseases (with an emphasis on lack of physical activity and its consequences) according to qualitative and quantitative sociological research...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29782831/mapping-cellular-polarity-networks-using-mass-spectrometry-based-strategies
#2
REVIEW
Avais M Daulat, Tania M Puvirajesinghe, Luc Camoin, Jean-Paul Borg
Cell polarity is a vital biological process involved in the building, maintenance and normal functioning of tissues in invertebrates and vertebrates. Unsurprisingly, molecular defects affecting polarity organization and functions have a strong impact on tissue homeostasis, embryonic development and adult life, and may directly or indirectly lead to diseases. Genetic studies have demonstrated the causative effect of several polarity genes in diseases, however much remains to be clarified before a comprehensive view of the molecular organization and regulation of the protein networks associated with polarity proteins is obtained...
May 18, 2018: Journal of Molecular Biology
https://www.readbyqxmd.com/read/29782368/tiny-moments-matter-promoting-professionalism-in-everyday-practice
#3
Elizabeth C Bernabeo, Benjamin Chesluk, Lorna Lynn
INTRODUCTION: Professionalism rests upon a number of individual, environmental, and societal level factors, leading to specific professional behavior in specific situations. Focusing on professional lapses to identify and remediate unprofessional physicians is incomplete. We explored professionalism in practicing internal medicine physicians in the context of everyday practice, to highlight how typical experiences contribute to positive, yet often unnoticed, professional behavior. METHODS: In-depth interviews were used to uncover 13 physicians' most meaningful experiences of professionalism...
May 16, 2018: Journal of Continuing Education in the Health Professions
https://www.readbyqxmd.com/read/29782304/role-of-in-vivo-reflectance-confocal-microscopy-in-the-analysis-of-melanocytic-lesions
#4
Elena-Daniela Serban, Francesca Farnetani, Giovanni Pellacani, Maria Magdalena Constantin
Worldwide melanoma incidence and mortality are increasing (1). Despite the ongoing research, advanced melanoma is still incurable; therefore, the most appropriate solution seems to be early detection combined with complete surgical excision (2). Since the diagnostic protocol of suspicious lesions includes a complete excision with safety margins (2), the problem of unnecessary scarring is significant. The real challenge in this case is to have a properly formulated diagnosis before acquiring a biopsy. Currently available non-invasive techniques are coherence tomography, digital dermoscopy, and reflectance confocal microscopy...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29781679/exploring-the-socio-ecological-levels-for-prevention-of-sexual-risk-behaviours-of-the-youth-in-umgungundlovu-district-municipality-kwazulu-natal
#5
Nelisiwe Khuzwayo, Myra Taylor
BACKGROUND: Prevention of youth sexual risk behaviour among the youth in uMgungundlovu District Municipality continues to be a primary challenge for public health and health promotion. Current prevention interventions are targeted at an individual level, whilst youth behaviour is influenced by many social and environmental factors. AIM: The aim of the study was to explore the factors influencing sexual risk behaviours of the youth at different socio-ecological levels in uMgungundlovu District Municipality...
March 7, 2018: African Journal of Primary Health Care & Family Medicine
https://www.readbyqxmd.com/read/29781173/discourse-and-cognition-in-speakers-with-acquired-brain-injury-abi-a-systematic-review
#6
REVIEW
Elizabeth Hill, Mary Claessen, Anne Whitworth, Mark Boyes, Roslyn Ward
BACKGROUND: Cognitive impairment, particularly of executive functioning, has been implicated in deficits in spoken discourse production following acquired brain injury (ABI). However, due to variation in the methodologies and heterogeneity of findings across studies, the nature and extent of this association is not well understood. AIMS: This review aims to synthesize the literature investigating associations between cognitive deficits and discourse impairment after ABI...
May 20, 2018: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/29781157/adverse-selection-and-supply-side-factors-in-the-enrollment-in-community-based-health-insurance-in-northwest-ethiopia-a-mixed-methodology
#7
Asmamaw Atafu, Soonman Kwon
BACKGROUND: Since 2010, the Ethiopian government introduced different measures to implement community-based health insurance (CBHI) schemes to improve access to health service and reduce the catastrophic effect of health care costs. OBJECTIVES: The aim of this study was to examine the determinants of enrollment in CBHI in Northwest Ethiopia. METHODS: In this study, we utilized a mix of quantitative (multivariate logistic regression applied to population survey linked with health facility survey) and qualitative (focus group discussion and in-depth interview) methods to better understand the factors that affect CBHI enrollment...
May 20, 2018: International Journal of Health Planning and Management
https://www.readbyqxmd.com/read/29780962/challenging-aspects-of-contemporary-cochlear-implant-electrode-array-design
#8
REVIEW
Pavel Mistrík, Claude Jolly, Daniel Sieber, Ingeborg Hochmair
Objective: A design comparison of current perimodiolar and lateral wall electrode arrays of the cochlear implant (CI) is provided. The focus is on functional features such as acoustic frequency coverage and tonotopic mapping, battery consumption and dynamic range. A traumacity of their insertion is also evaluated. Methods: Review of up-to-date literature. Results: Perimodiolar electrode arrays are positioned in the basal turn of the cochlea near the modiolus...
December 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29780911/long-term-visual-outcomes-of-laser-anterior-ciliary-excision
#9
AnnMarie Hipsley, Brad Hall, Karolinne Maia Rocha
Purpose: To determine the long-term visual outcomes of six eyes of 3 patients up to 13 years following the Laser Anterior Ciliary Excision (LaserACE) procedure. Methods: Three male patients of ages 59, 59, and 60 presented for evaluation at Storm Eye Institute, Medical University of South Carolina at 8, 10, and 13 years after the LaserACE procedure for presbyopia, respectively. All 3 patients had a history of laser vision correction (LVC) prior to LaserACE treatment...
June 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29778584/evaluating-the-capacity-of-california-s-publicly-funded-universities-to-provide-medication-abortion
#10
Sarah Raifman, Patricia Anderson, Shelly Kaller, Diane Tober, Daniel Grossman
OBJECTIVE: To explore the capacity of the University of California (UC) and California State University (CSU) student health centers to provide medication abortion (MA), to identify gaps in resources required to implement proposed Senate Bill 320, which would mandate the provision of MA on UC and CSU campuses, and to explore California student health center staff perspectives on the benefits and challenges of providing MA. STUDY DESIGN: UC and CSU student health center (SHC) staff participated in a self-administered online survey; we conducted in-depth data collection including site visits and conference calls at a subset of campuses...
May 17, 2018: Contraception
https://www.readbyqxmd.com/read/29777979/a-qualitative-study-of-disengagement-in-disadvantaged-areas-of-the-uk-you-come-through-your-door-and-you-lock-that-door
#11
M Romeo-Velilla, N Ellis, G Hurst, S Grogan, C Gidlow
Health inequalities are a major concern in the UK. Power imbalances are associated with health inequalities and should be challenged through health promotion and empowering strategies, enabling individuals who feel powerless to take control over their own life and act on the determinants of health (Green and Tones, 2010). This study aimed to explore resident expectations of a community engagement programme that intended to empower communities to take action on pre-identified priorities. The programme targeted communities in deprived areas of a mid-sized city in the UK...
May 16, 2018: Health & Place
https://www.readbyqxmd.com/read/29777645/-childbirth-is-not-a-sickness-a-woman-should-struggle-to-give-birth-exploring-continuing-popularity-of-home-births-in-western-kenya
#12
Violet Naanyu, Joyce Baliddawa, Beatrice Koech, Julie Karfakis, Nancy Nyagoha
More than 95% of Kenyan women receive antenatal care (ANC) and only 62% access skilled delivery. To explore women's opinion on delivery location, 20 focus group discussions were conducted at an urban and rural setting in western Kenya. Participants included health care workers, traditional birth attendants (TBAs), and women who attended at least four ANC visits and delivered. Six in-depth interviews were also conducted with a combination of women who gave birth in a facility and at home. Discussions were digitally recorded and transcribed for analysis...
March 2018: African Journal of Reproductive Health
https://www.readbyqxmd.com/read/29777644/closing-the-gap-between-people-and-programs-lessons-from-implementation-of-social-accountability-for-family-planning-and-reproductive-health-in-uganda
#13
Vicky Boydell, Stella Neema, Kelsey Wright, Karen Hardee
Globally, women's access to modern contraception can be attributed to poor service conditions and care. Growing evidence from across the health sector has found that social accountability approaches have the potential to improve the quality of care and therefore the utilization of health services, little of this evidence relates to family planning and reproductive health programs. This paper therefore assessed the results of retrospective implementation research into a five-year social accountability project in Uganda that focused on family planning and reproductive health...
March 2018: African Journal of Reproductive Health
https://www.readbyqxmd.com/read/29776312/on-the-prospects-of-using-high-intensity-thz-pulses-to-induce-ultrafast-temperature-jumps-in-liquid-water
#14
Pankaj Kr Mishra, Vincent Bettaque, Oriol Vendrell, Robin Santra, Ralph Welsch
Ultrashort, high-intensity THz pulses, e.g., created at free-electron laser facilities, allow for direct investigation as well as the driving of intermolecular modes in liquids like water and thus will deepen our understanding of the hydrogen bonding network. In this work, the temperature-jump (T-jump) of water induced by THz radiation is simulated for ten different THz frequencies in the range from 3 to 30 THz and five different pulse intensities in the range from 1 × 1011 to 5 × 1012 W/cm2 employing both ab initio molecular dynamics (AIMD) and force field molecular dynamics (FFMD) approaches...
May 18, 2018: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29775694/advance-care-planning-in-a-multi-cultural-family-centric-community-a-qualitative-study-of-healthcare-professionals-patients-and-caregivers-perspectives
#15
Sumytra Menon, Marijke Kars, Chetna Malhotra, Alastair V Campbell, J J M van Delden
CONTEXT: Advance care planning has been shown to improve end-of-life care but it was developed in the USA and most research has been conducted in western communities. OBJECTIVES: We aimed to study the attitudes and perceptions of patients with life-limiting illnesses, informal caregivers, doctors, nurses and medical social workers regarding advance care planning in a multi-cultural family-centric community. METHODS: We conducted an explorative qualitative study, using focus groups and individual in-depth interviews...
May 15, 2018: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29773606/optimising-experimental-research-in-respiratory-diseases-an-ers-statement
#16
Philippe Bonniaud, Aurélie Fabre, Nelly Frossard, Christophe Guignabert, Mark Inman, Wolfgang M Kuebler, Tania Maes, Wei Shi, Martin Stampfli, Stefan Uhlig, Eric White, Martin Witzenrath, Pierre-Simon Bellaye, Bruno Crestani, Oliver Eickelberg, Heinz Fehrenbach, Andreas Guenther, Gisli Jenkins, Guy Joos, Antoine Magnan, Bernard Maitre, Ulrich A Maus, Petra Reinhold, Juanita H J Vernooy, Luca Richeldi, Martin Kolb
Experimental models are critical for the understanding of lung health and disease and are indispensable for drug development. However, the pathogenetic and clinical relevance of the models is often unclear. Further, the use of animals in biomedical research is controversial from an ethical perspective.The objective of this task force was to issue a statement with research recommendations about lung disease models by facilitating in-depth discussions between respiratory scientists, and to provide an overview of the literature on the available models...
May 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29773527/acceptability-and-feasibility-of-real-time-antiretroviral-therapy-adherence-interventions-in-rural-uganda-mixed-method-pilot-randomized-controlled-trial
#17
Angella Musiimenta, Esther C Atukunda, Wilson Tumuhimbise, Emily E Pisarski, Melanie Tam, Monique A Wyatt, Norma C Ware, Jessica E Haberer
BACKGROUND: Wireless electronic adherence monitors can detect antiretroviral therapy (ART) adherence lapses and trigger interventions in real time, thus potentially avoiding unnecessary HIV viremia. Evidence about the acceptability and feasibility of these monitors and associated interventions, however, is limited. OBJECTIVE: The aim of this study was to assess the acceptability and feasibility of real-time adherence monitoring linked to text messaging (short message service, SMS) reminders and notifications to support adherence among individuals living with HIV who are taking ART in rural southwestern Uganda...
May 17, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29772284/effect-of-excipient-properties-water-activity-and-water-content-on-the-disproportionation-of-a-pharmaceutical-salt
#18
Mitulkumar A Patel, Suman Luthra, Sheri L Shamblin, Kapildev K Arora, Joseph F Krzyzaniak, Lynne S Taylor
Excipients are crucial components of most pharmaceutical formulations. In the case of a solid oral dosage formulation containing the salt form of a weakly ionizable drug, excipient selection is critical, as some excipients are known to cause salt disproportionation (conversion of salt to the free form). Therefore, robust formulation design necessitates an in-depth understanding of the factors impacting salt disproportionation during processing or storage as this can negatively impact product quality and performance...
May 14, 2018: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29772081/a-photon-source-model-based-on-particle-transport-in-a-parameterized-accelerator-structure-for-monte-carlo-dose-calculations
#19
Yoshiki Ishizawa, Suguru Dobashi, Noriyuki Kadoya, Kengo Ito, Takahito Chiba, Yoshiki Takayama, Kiyokazu Sato, Ken Takeda
PURPOSE: An accurate source model of a medical linear accelerator is essential for Monte Carlo (MC) dose calculations. This study aims to propose an analytical photon source model based on particle transport in parameterized accelerator structures, focusing on a more realistic determination of linac photon spectra compared to existing approaches. METHODS: We designed the primary and secondary photon sources based on the photons attenuated and scattered by a parameterized flattening filter...
May 17, 2018: Medical Physics
https://www.readbyqxmd.com/read/29771371/allele-phasing-greatly-improves-the-phylogenetic-utility-of-ultraconserved-elements
#20
Tobias Andermann, Alexandre M Fernandes, Urban Olsson, Mats Töpel, Bernard Pfeil, Bengt Oxelman, Alexandre Aleixo, Brant C Faircloth, Alexandre Antonelli
Advances in high-throughput sequencing techniques now allow relatively easy and affordable sequencing of large portions of the genome, even for non-model organisms. Many phylogenetic studies reduce costs by focusing their sequencing efforts on a selected set of targeted loci, commonly enriched using sequence capture. The advantage of this approach is that it recovers a consistent set of loci, each with high sequencing depth, which leads to more confidence in the assembly of target sequences. High sequencing depth can also be used to identify phylogenetically informative allelic variation within sequenced individuals, but allele sequences are infrequently assembled in phylogenetic studies...
May 15, 2018: Systematic Biology
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