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https://www.readbyqxmd.com/read/29345416/a-qualitative-study-experiences-of-stigma-by-people-with-mental-health-problems
#1
Charlotte Huggett, Michèle D Birtel, Yvonne F Awenat, Paul Fleming, Sophie Wilkes, Shirley Williams, Gillian Haddock
OBJECTIVES: Prior research has examined various components involved in the impact of public and internalized stigma on people with mental health problems. However, studies have not previously investigated the subjective experiences of mental health stigma by those affected in a non-statutory treatment-seeking population. DESIGN: An in-depth qualitative study was conducted using thematic analysis to investigate the experiences of stigma in people with mental health problems...
January 18, 2018: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/29345261/an-inert-3d-emulsification-device-for-individual-precipitation-and-concentration-of-amorphous-drug-nanoparticles
#2
T Lorenz, S Bojko, H Bunjes, A Dietzel
Nanosizing increases the specific surface of drug particles, leading to faster dissolution inside the organism and improving the bioavailability of poorly water-soluble drugs. A novel approach for the preparation of drug nanoparticles in water using chemically inert microfluidic emulsification devices is presented in this paper. A lithographic fabrication sequence was established, allowing fabrication of intersecting and coaxial channels of different depths in glass as is required for 3D flow-focusing. Fenofibrate was used as a model for active pharmaceutical ingredients with very low water solubility in the experiments...
January 18, 2018: Lab on a Chip
https://www.readbyqxmd.com/read/29345256/caregiver-perspectives-on-communication-during-hospitalization-at-an-academic-pediatric-institution-a-qualitative-study
#3
Lauren G Solan, Andrew F Beck, Stephanie A Shardo, Hadley S Sauers-Ford, Jeffrey M Simmons, Samir S Shah, Susan N Sherman
OBJECTIVE: Communication among those involved in a child's care during hospitalization can mitigate or exacerbate family stress and confusion. As part of a broader qualitative study, we present an in-depth understanding of communication issues experienced by families during their child's hospitalization and during the transition to home. METHODS: Focus groups and individual interviews stratified by socioeconomic status included caregivers of children recently discharged from a children's hospital after acute illnesses...
January 18, 2018: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29345072/genetic-monitoring-of-horses-in-the-czech-republic-a-large-scale-study-with-a-focus-on-the-czech-autochthonous-breeds
#4
L Putnová, R Štohl, I Vrtková
We propose the first comprehensive in-depth study monitoring horses in the Czech Republic. We scanned 9,289 animals from 44 populations for 17 equine STRs. Other equids analysed involved Equus przewalskii and Equus asinus. The total of 228 different alleles were detected, with the mean number of 13.4 per locus. The highest allelic richness (AR) was found in the Welsh Part Bred (6.01), followed by the Camargue (5.93) and Czech Sport Pony (5.91), whereas the Friesian exhibited the lowest AR (3.06). Interpopulation differences explained approximately nine per cent of the total genetic diversity...
February 2018: Journal of Animal Breeding and Genetics, Zeitschrift Für Tierzüchtung und Züchtungsbiologie
https://www.readbyqxmd.com/read/29344463/team-based-learning-strategy-in-biochemistry-perceptions-and-attitudes-of-faculty-and-1st-year-medical-students
#5
Namrata Chhabra, Sahiba Kukreja, Sarah Chhabra, Sahil Chhabra, Sameenah Khodabux, Harshal Sabane
Background: Team-based learning (TBL) strategy has been widely adapted by medical schools all over the world, but the reports regarding the perceptions and the attitudes of faculty and undergraduate medical students towards TBL approach have been conflicting. Aim: The study aimed to introduce TBL strategy in curriculum of Biochemistry after evaluating its effectiveness through perceptions and attitudes of faculty and 1st-year medical students. Materials and Methods: One hundred and fifty students of first professional M...
December 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29344455/qualitative-assessment-of-learning-strategies-among-medical-students-using-focus-group-discussions-and-in-depth-interviews
#6
Anuradha Sujai Joshi, Jaishree Deepak Ganjiwale, Jagdish Varma, Praveen Singh, Jyoti Nath Modi, Tejinder Singh
Background: Globally, students with top academic performance and high intellectual capacity usually opt to study medicine. However, once students get enrolled, their academic performance varies widely. Such variations appear to be determined by various factors, one of them being types of learning strategies adopted by students. The learning strategies utilized by the students with better academic performance are likely to be more effective learning strategies. Aims and Objectives: The objective is to identify effective learning strategies used by medical students...
December 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29344454/critical-review-of-family-health-advisory-services-assessment-in-mbbs-training-program-in-community-medicine
#7
Kiran Goswami, H Salve, S Malhotra, Y Kumar
Context: Family Health Advisory Services (FHAS) posting as well as its assessment is resource demanding but fails to enjoy priority. Study focuses on a holistic overview of the assessment process to understand need for change. Aims: The aim of this study is to identify perceived gaps in current assessment practices related to FHAS posting. Settings and Design: A cross-sectional mixed method study among all the V semester students currently undergoing assessment for the posting, past students (selected VII semester students and interns), preceptors (supervising residents - postgraduate students in department and senior resident, health assistants, medical social service officer), and involved faculty...
December 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29344418/advances-in-the-studies-of-ginkgo-biloba-leaves-extract-on-aging-related-diseases
#8
REVIEW
Wei Zuo, Feng Yan, Bo Zhang, Jiantao Li, Dan Mei
The prevalence of degenerative disorders in public health has promoted in-depth investigations of the underlying pathogenesis and the development of new treatment drugs. Ginkgo biloba leaves extract (EGb) is obtained from Ginkgo biloba leaves and has been used for thousands of years. In recent decades, both basic and clinical studies have established the effects of EGb. It is widely used in various degenerative diseases such as cerebrovascular disease, Alzheimer's disease, macroangiopathy and more. Here, we reviewed several pharmacological mechanisms of EGb, including its antioxidant properties, prevention of mitochondrial dysfunctions, and effect on apoptosis...
December 2017: Aging and Disease
https://www.readbyqxmd.com/read/29343215/women-s-decision-making-processes-and-the-influences-on-their-mode-of-birth-following-a-previous-caesarean-section-in-taiwan-a-qualitative-study
#9
Shu-Wen Chen, Alison M Hutchinson, Cate Nagle, Tracey K Bucknall
BACKGROUND: Vaginal birth after caesarean (VBAC) is an alternative option for women who have had a previous caesarean section (CS); however, uptake is limited because of concern about the risks of uterine rupture. The aim of this study was to explore women's decision-making processes and the influences on their mode of birth following a previous CS. METHODS: A qualitative approach was used. The research comprised three stages. Stage I consisted of naturalistic observation at 33-34 weeks' gestation...
January 17, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29343213/the-community-is-just-a-small-circle-citizen-participation-in-the-free-maternal-and-child-healthcare-programme-of-enugu-state-nigeria
#10
Daniel C Ogbuabor, Obinna E Onwujekwe
BACKGROUND: There is a gap in knowledge about how citizen participation impacts governance of free healthcare policies for universal health coverage in low- and middle-income countries. OBJECTIVE: This study provides evidence about how social accountability initiatives influenced revenue generation, pooling and fund management, purchasing and capacity of health facilities implementing the free maternal and child healthcare programme (FMCHP) in Enugu State, Nigeria...
2018: Global Health Action
https://www.readbyqxmd.com/read/29342105/neuroimmune-driven-neuropathic-pain-establishment-a-focus-on-gender-differences
#11
REVIEW
Vincenzo Coraggio, Francesca Guida, Serena Boccella, Mariantonietta Scafuro, Salvatore Paino, Domenico Romano, Sabatino Maione, Livio Luongo
The role of neuroinflammatory cells in the establishment of neuropathic pain has been investigated in depth in the last few years. In particular, microglia have been shown to be key players in the induction of tactile allodynia, as they release proinflammatory molecules that, in turn, sensitize nociceptive neurons within the spinal cord. However, the role of peripheral immune cells such as macrophages, infiltrating monocytes, mast cells, and T-cells has been highlighted in the last few studies, even though the data are still conflicting and need to be clarified...
January 17, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29342055/benefit-of-preoperative-temporal-bone-ct-for-atraumatic-cochlear-implantation
#12
Alexandre Karkas, Nicolas Menjot de Champfleur, Alain Uziel, Michel Mondain, Jean-Luc Puel, Frédéric Venail
HYPOTHESIS: Evaluate the benefit of preoperative surgical planning using computed tomography (CT) for atraumatic cochlear implantation. BACKGROUND: The surgical technique has a direct impact on hearing and structure preservation. Much interest has been given to depth of electrode insertion. We focused on electrode diameter depending on exposure of round window membrane (RWM) as calculated on preoperative CT. METHODS: Measurements were calculated radiologically and anatomically on 10 temporal bones...
January 16, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29339987/physiological-demands-morphological-characteristics-physical-abilities-and-injuries-of-female-soccer-players
#13
Zoran Milanović, Goran Sporiš, Nic James, Nebojša Trajković, Aleksandar Ignjatović, Hugo Sarmento, Athos Trecroci, Bruno Miguel Borges Mendes
The popularity of female soccer is increasing as well as the number of females playing soccer. Similarly, over the last twenty or so years, research in soccer has increased significantly, but a large disparity exists in the volume of studies involving male and female players. As a consequence of this, female players remain less well understood compared to males. The purpose of the present narrative review was to describe morphological characteristics, physiological demands, physical abilities and injuries in female soccer players...
December 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/29338784/advancing-sti-priorities-in-the-sdg-era-priorities-for-action
#14
EDITORIAL
Matthew F Chersich, Sinead Delany-Moretlwe, Greg Martin, Helen Rees
The Sustainable Development Goals present an opportunity to reimagine and then reconfigure the approach to controlling sexually transmitted infections (STIs). The predilection of STIs for women and for vulnerable populations means that services that ameliorate STIs, by their nature, enhance equity, a key focus of the goals. Given the considerable breadth and depth of the goals, it is important to locate points of convergence between the SDGs and STIs, further craft synergies with HIV and select a few population groups and settings to prioritise...
January 16, 2018: Globalization and Health
https://www.readbyqxmd.com/read/29337262/longitudinal-patterns-and-response-lengths-of-algae-in-riverine-ecosystems-a-model-analysis-emphasising-benthic-pelagic-interactions
#15
Christoph G Jäger, Dietrich Borchardt
In riverine ecosystems primary production is principally possible in two habitats: in the benthic layer by sessile algae and in the surface water by planktonic algae being transported downstream. The relevance of these two habitats generally changes along the rivers' continuum. However, analyses of the interaction of algae in these two habitats and their controlling factors in riverine ecosystems are, so far, very rare. We use a simplified advection-diffusion model system combined with ecological process kinetics to analyse the interaction of benthic and planktonic algae and nutrients along idealised streams and rivers at regional to large scales...
January 11, 2018: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/29335637/expression-profiling-of-host-and-virus-during-a-coccolithophore-bloom-provides-insights-into-the-role-of-viral-infection-in-promoting-carbon-export
#16
Uri Sheyn, Shilo Rosenwasser, Yoav Lehahn, Noa Barak-Gavish, Ron Rotkopf, Kay D Bidle, Ilan Koren, Daniella Schatz, Assaf Vardi
The cosmopolitan coccolithophore Emiliania huxleyi is a unicellular eukaryotic alga that forms vast blooms in the oceans impacting large biogeochemical cycles. These blooms are often terminated due to infection by the large dsDNA virus, E. huxleyi virus (EhV). It was recently established that EhV-induced modulation of E. huxleyi metabolism is a key factor for optimal viral infection cycle. Despite the huge ecological importance of this host-virus interaction, the ability to assess its spatial and temporal dynamics and its possible impact on nutrient fluxes is limited by current approaches that focus on quantification of viral abundance and biodiversity...
January 15, 2018: ISME Journal
https://www.readbyqxmd.com/read/29335539/brain-activity-patterns-in-high-throughput-electrophysiology-screen-predict-both%C3%A2-drug-efficacies-and-side-effects
#17
Peter M Eimon, Mostafa Ghannad-Rezaie, Gianluca De Rienzo, Amin Allalou, Yuelong Wu, Mu Gao, Ambrish Roy, Jeffrey Skolnick, Mehmet Fatih Yanik
Neurological drugs are often associated with serious side effects, yet drug screens typically focus only on efficacy. We demonstrate a novel paradigm utilizing high-throughput in vivo electrophysiology and brain activity patterns (BAPs). A platform with high sensitivity records local field potentials (LFPs) simultaneously from many zebrafish larvae over extended periods. We show that BAPs from larvae experiencing epileptic seizures or drug-induced side effects have substantially reduced complexity (entropy), similar to reduced LFP complexity observed in Parkinson's disease...
January 15, 2018: Nature Communications
https://www.readbyqxmd.com/read/29334946/surmounting-difficulties-to-provide-home-based-neonatal-care-reflections-of-community-health-workers
#18
Abhijit Shrinivas Prabhughate, Pearl Tiwari, Shubhangi Sohoni, Vallaree Anant Morgaonkar, Ajay Gajanan Phatak, Somashekhar Marutirao Nimbalkar, Anagha Anand Mahajani
BACKGROUND: In India, community health workers' (CHW) effectiveness in providing home-based neonatal care (HBNC) has been well documented. The nature of challenges faced and strategies adopted while providing HBNC services need to be studied in-depth. METHODS: A qualitative study to understand the challenges faced and strategies used by Sakhis (women CHW) while providing services as part of a HBNC program implemented by a non-profit organization. Data consisted of 20 in-depth interviews and three focus group discussions (FGD) with Sakhis...
January 15, 2018: BMC Women's Health
https://www.readbyqxmd.com/read/29334890/characterization-of-the-late-embryogenesis-abundant-lea-proteins-family-and-their-role-in-drought-stress-tolerance-in-upland-cotton
#19
Richard Odongo Magwanga, Pu Lu, Joy Nyangasi Kirungu, Hejun Lu, Xingxing Wang, Xiaoyan Cai, Zhongli Zhou, Zhenmei Zhang, Haron Salih, Kunbo Wang, Fang Liu
BACKGROUND: Late embryogenesis abundant (LEA) proteins are large groups of hydrophilic proteins with major role in drought and other abiotic stresses tolerance in plants. In-depth study and characterization of LEA protein families have been carried out in other plants, but not in upland cotton. The main aim of this research work was to characterize the late embryogenesis abundant (LEA) protein families and to carry out gene expression analysis to determine their potential role in drought stress tolerance in upland cotton...
January 15, 2018: BMC Genetics
https://www.readbyqxmd.com/read/29334618/exploring-masculinities-sexual-health-and-wellbeing-across-areas-of-high-deprivation-in-scotland-the-depth-of-the-challenge-to-improve-understandings-and-practices
#20
Karen Lorimer, Lesley McMillan, Lisa McDaid, Dona Milne, Siân Russell, Kate Hunt
Within and across areas of high deprivation, we explored constructions of masculinity in relation to sexual health and wellbeing, in what we believe to be the first UK study to take this approach. Our sample of 116 heterosexual men and women age 18-40 years took part in individual semi-structured interviews (n = 35) and focus group discussions (n = 18), across areas in Scotland. Drawing on a socio-ecological framework, findings revealed experience in places matter, with gender practices rooted in a domestically violent milieu, where localised, socio-cultural influences offered limited opportunities for more egalitarian performances of masculinity...
January 12, 2018: Health & Place
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