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https://www.readbyqxmd.com/read/28920518/the-indirect-costs-of-underfunding-foreign-partners-in-global-health-research-a-case-study
#1
Johanna T Crane, Irene Andia Biraro, Tamer M Fouad, Yap Boum, David R Bangsberg
This study of a global health research partnership assesses how U.S. fiscal administrative policies impact capacity building at foreign partner institutions. We conducted a case study of a research collaboration between Mbarara University of Science and Technology (MUST) in Mbarara, Uganda, and originally the University of California San Francisco (UCSF), but now Massachusetts General Hospital (MGH). Our case study is based on three of the authors' experiences directing and working with this partnership from its inception in 2003 through 2015...
September 16, 2017: Global Public Health
https://www.readbyqxmd.com/read/28874933/head-ct-for-minor-head-injury-presenting-to-the-emergency-department-in-the-era-of-choosing-wisely
#2
John DeAngelis, Valerie Lou, Timmy Li, Henry Tran, Praneeta Bremjit, Molly McCann, Peter Crane, Courtney M C Jones
INTRODUCTION: The Choosing Wisely campaign currently recommends avoiding computed tomography (CT) of the head in low-risk emergency department (ED) patients with minor head injury, based on validated decision rules. However, the degree of adherence to this guideline in clinical practice is unknown. The objective of this study was to evaluate adherence to the Choosing Wisely campaign's recommendations regarding head CT imaging of patients with minor head injury in the ED. METHODS: We conducted a retrospective cohort study of adult ED patients at a Level I trauma center...
August 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28859770/no-245-alcohol-use-and-pregnancy-consensus-clinical-guidelines
#3
George Carson, Lori Vitale Cox, Joan Crane, Pascal Croteau, Lisa Graves, Sandra Kluka, Gideon Koren, Marie-Jocelyne Martel, Deana Midmer, Irena Nulman, Nancy Poole, Vyta Senikas, Rebecca Wood
OBJECTIVE: To establish national standards of care for the screening and recording of alcohol use and counselling on alcohol use of women of child-bearing age and pregnant women based on the most up-to-date evidence. EVIDENCE: Published literature was retrieved through searches of PubMed, CINAHL, and the Cochrane Library in May 2009 using appropriate controlled vocabulary (e.g., pregnancy complications, alcohol drinking, prenatal care) and key words (e.g., pregnancy, alcohol consumption, risk reduction)...
September 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28854081/treatment-of-axillary-web-syndrome-using-instrument-assisted-soft-tissue-mobilization-and-thoracic-manipulation-for-associated-thoracic-rotation-dysfunction-a-case-report
#4
Patricia Crane, Jaclyn Ladden, Danielle Monica
PURPOSE: There is a paucity of research that investigates physical therapy management for patients with axillary web syndrome (AWS) and thoracic rotation dysfunction. The purpose of this case report is to describe the management of a patient with AWS and thoracic rotation dysfunction using an impairment-based approach that includes instrument assisted soft tissue mobilization (IASTM), thoracic manipulation, and stretching. CASE DESCRIPTION: The patient was a 48-year-old female with a past medical history of bilateral breast cancer with a bilateral latissimus dorsi flap reconstruction...
August 30, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28843556/a-new-technique-for-probing-chirality-via-photoelectron-circular-dichroism
#5
J Miles, D Fernandes, A Young, C M M Bond, S W Crane, O Ghafur, D Townsend, J Sá, J B Greenwood
We present a proof-of-principle approach for discriminating chiral enantiomers based on the phenomenon of multiphoton photoelectron circular dichroism. A novel stereo detection setup was used to measure the number of photoelectrons emitted from chiral molecules in directions parallel or anti-parallel to the propagation of the ionising femtosecond laser pulses. In this study, we show how these asymmetries in the ketones camphor and fenchone depend upon the ellipticity of the laser pulses and the enantiomeric excess of the sample...
September 1, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28816138/lymphocyte-nadir-and-esophageal-cancer-survival-outcomes-after-chemoradiation-therapy
#6
Rajayogesh Davuluri, Wen Jiang, Penny Fang, Cai Xu, Ritsuko Komaki, Daniel R Gomez, James Welsh, James D Cox, Christopher H Crane, Charles C Hsu, Steven H Lin
PURPOSE: Host immunity may affect the outcome in patients with esophageal cancer. We sought to identify factors that influenced absolute lymphocyte count (ALC) nadir during chemoradiation therapy (CRT) for esophageal cancer (EC) and looked for clinically relevant associations with survival. METHODS AND MATERIALS: 504 patients with stage I-III EC (2007-2013) treated with neoadjuvant or definitive CRT with weekly ALC determinations made during treatment were analyzed...
September 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28761945/prescription-opioid-use-misuse-and-use-disorders-in-u-s-adults-2015-national-survey-on-drug-use-and-health
#7
Beth Han, Wilson M Compton, Carlos Blanco, Elizabeth Crane, Jinhee Lee, Christopher M Jones
Background: Despite the continuing epidemic of opioid misuse, data on the prevalence of prescription opioid use, misuse, and use disorders are limited. Objective: To estimate the prevalence of prescription opioid use, misuse, and use disorders and motivations for misuse among U.S. adults. Design: Survey. Setting: The 2015 National Survey on Drug Use and Health (NSDUH). Participants: 72 600 eligible civilian, noninstitutionalized adults were selected for NSDUH, and 51 200 completed the survey interview...
September 5, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28757901/teacher-competence-in-mindfulness-based-cognitive-therapy-for-depression-and-its-relation-to-treatment-outcome
#8
Marloes J Huijbers, Rebecca S Crane, Willem Kuyken, Lot Heijke, Ingrid van den Hout, A Rogier T Donders, Anne E M Speckens
As mindfulness-based cognitive therapy (MBCT) becomes an increasingly mainstream approach for recurrent depression, there is a growing need for practitioners who are able to teach MBCT. The requirements for being competent as a mindfulness-based teacher include personal meditation practice and at least a year of additional professional training. This study is the first to investigate the relationship between MBCT teacher competence and several key dimensions of MBCT treatment outcomes. Patients with recurrent depression in remission (N = 241) participated in a multi-centre trial of MBCT, provided by 15 teachers...
2017: Mindfulness
https://www.readbyqxmd.com/read/28749824/the-relationship-between-efavirenz-as-initial-antiretroviral-therapy-and-suicidal-thoughts-among-hiv-infected-adults-in-routine-care
#9
Angela M Bengtson, Brian W Pence, Katie R Mollan, Jessie K Edwards, Richard D Moore, Conall O'Cleirigh, Ellen F Eaton, Joseph J Eron, Mari M Kitahata, W Christopher Mathews, Heidi Crane, Michael J Mugavero
BACKGROUND: Evidence about the effect of initiating efavirenz-containing combination antiretroviral therapy (ART) as first-line therapy on suicidal thoughts remains conflicting. METHODS: Using data from a cohort of HIV-infected adults enrolled in routine care across 5 sites in the United States, we included participants with a baseline patient-reported outcome measure and detectable viral load who initiated ART between 2011 and 2014. Participants were followed until the earliest of the following: first suicidal thoughts, discontinuation of initial ART regimen, death, loss to care (>12 months with no HIV appointments), or administrative censoring (2014 to 2015)...
July 26, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28738509/ambient-sediment-quality-conditions-in-minnesota-lakes-usa-effects-of-watershed-parameters-and-aquatic-health-implications
#10
Judy L Crane
Surficial sediments were collected from 50 randomly selected Minnesota lakes, plus four a priori reference lakes, in 2007. The lakes encompassed broad geographic coverage of the state and included a variety of major land uses in the surrounding watersheds. Sediment samples were analyzed for a suite of metals, metalloids, persistent organic pollutants, total organic carbon, and particle size fractions. In addition, a small fish survey was conducted to assess PBDEs in both whole fish and fish tissues. Sediment quality in this set of lakes ranged from good (43%) to moderate (57%) based on an integrative measure of multiple contaminants...
December 31, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28731431/association-between-cholesterol-exposure-and-neuropathological-findings-the-act-study
#11
Brianne M Bettcher, M Colin Ard, Bruce R Reed, Andreana Benitez, Amanda Simmons, Eric B Larson, Josh A Sonnen, Thomas J Montine, Ge Li, C Dirk Keene, Paul K Crane, Dan Mungas
We characterized the relationship between late life cholesterol exposure and neuropathological outcomes in a community-based, older adult cohort. Adult Changes in Thought (ACT) is a cohort study that enrolls consenting, randomly selected, non-demented people aged ≥65 from a healthcare delivery system. We used late life HDL and total cholesterol lab values from Group Health computerized records, and calculated HDL and non-HDL levels. We evaluated neuropathological outcomes of Alzheimer's disease, cerebral amyloid angiopathy, vascular brain injury, and Lewy body disease...
2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28692699/multiple-quay-cranes-scheduling-for-double-cycling-in-container-terminals
#12
Yanling Chu, Xiaoju Zhang, Zhongzhen Yang
Double cycling is an efficient tool to increase the efficiency of quay crane (QC) in container terminals. In this paper, an optimization model for double cycling is developed to optimize the operation sequence of multiple QCs. The objective is to minimize the makespan of the ship handling operation considering the ship balance constraint. To solve the model, an algorithm based on Lagrangian relaxation is designed. Finally, we compare the efficiency of the Lagrangian relaxation based heuristic with the branch-and-bound method and a genetic algorithm using instances of different sizes...
2017: PloS One
https://www.readbyqxmd.com/read/28682269/adaptive-critic-nonlinear-robust-control-a-survey
#13
Ding Wang, Haibo He, Derong Liu
Adaptive dynamic programming (ADP) and reinforcement learning are quite relevant to each other when performing intelligent optimization. They are both regarded as promising methods involving important components of evaluation and improvement, at the background of information technology, such as artificial intelligence, big data, and deep learning. Although great progresses have been achieved and surveyed when addressing nonlinear optimal control problems, the research on robustness of ADP-based control strategies under uncertain environment has not been fully summarized...
October 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28644003/chemical-sensor-based-upon-stress-induced-changes-in-the-permeability-of-a-magnetoelastic-wire
#14
Nahla A Hatab, Nichole A Crane, David K Mee, L Neville Howell, Larry R Mooney, Russell L Hallman, Michael J Sepaniak, Vincent E Lamberti
We introduce a chemical sensing technology, named ChIMES (Chemical Identification through Magneto-Elastic Sensing), that can detect a broad range of targets and that has the capability of untethered communication through a metallic or nonmetallic barrier. These features enable many applications in which penetrations into the sampled environment are unwanted or infeasible because of health, safety, or environmental concerns, such as following the decomposition of a dangerous material in a sealed container. The sensing element is passive and consists of a target response material hard-coupled to a magnetoelastic wire...
June 23, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28632787/risk-of-alzheimer-s-disease-or-dementia-following-a-cancer-diagnosis
#15
Erin J Aiello Bowles, Rod L Walker, Melissa L Anderson, Sascha Dublin, Paul K Crane, Eric B Larson
OBJECTIVE: We evaluated dementia and Alzheimer's disease (AD) risks after a cancer diagnosis in a population-based prospective cohort, the Adult Changes in Thought (ACT) study. METHODS: We followed community-dwelling people aged ≥65 years without dementia at study entry for incident dementia and AD from 1994-2015. We linked study data with cancer registry data and categorized cancer diagnoses as prevalent (diagnosed before ACT study enrollment) or incident (diagnosed during follow-up)...
2017: PloS One
https://www.readbyqxmd.com/read/28629232/latent-profile-analysis-of-the-five-facet-mindfulness-questionnaire-in-a-sample-with-a-history-of-recurrent-depression
#16
Jenny Gu, Anke Karl, Ruth Baer, Clara Strauss, Thorsten Barnhofer, Catherine Crane
BACKGROUND: Extending previous research, we applied latent profile analysis in a sample of adults with a history of recurrent depression to identify subgroups with distinct response profiles on the Five Facet Mindfulness Questionnaire and understand how these relate to psychological functioning. METHOD: The sample was randomly divided into two subsamples to first examine the optimal number of latent profiles (test sample; n = 343) and then validate the identified solution (validation sample; n = 340)...
June 1, 2017: Assessment
https://www.readbyqxmd.com/read/28623185/a-web-based-data-collection-platform-for-multisite-randomized-behavioral-intervention-trials-development-key-software-features-and-results-of-a-user-survey
#17
Riddhi A Modi, Michael J Mugavero, Rivet K Amico, Jeanne Keruly, Evelyn Byrd Quinlivan, Heidi M Crane, Alfredo Guzman, Anne Zinski, Solange Montue, Katya Roytburd, Anna Church, James H Willig
BACKGROUND: Meticulous tracking of study data must begin early in the study recruitment phase and must account for regulatory compliance, minimize missing data, and provide high information integrity and/or reduction of errors. In behavioral intervention trials, participants typically complete several study procedures at different time points. Among HIV-infected patients, behavioral interventions can favorably affect health outcomes. In order to empower newly diagnosed HIV positive individuals to learn skills to enhance retention in HIV care, we developed the behavioral health intervention Integrating ENGagement and Adherence Goals upon Entry (iENGAGE) funded by the National Institute of Allergy and Infectious Diseases (NIAID), where we deployed an in-clinic behavioral health intervention in 4 urban HIV outpatient clinics in the United States...
June 16, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28608971/the-experiences-of-pregnant-women-in-an-interventional-clinical-trial-research-in-pregnancy-ethics-ripe-study
#18
Angela Ballantyne, Susan Pullon, Lindsay Macdonald, Christine Barthow, Kristen Wickens, Julian Crane
There is increasing global pressure to ensure that pregnant women are responsibly and safely included in clinical research in order to improve the evidence base that underpins healthcare delivery during pregnancy. One supposed barrier to inclusion is the assumption that pregnant women will be reluctant to participate in research. There is however very little empirical research investigating the views of pregnant women. Their perspective on the benefits, burdens and risks of research is a crucial component to ensuring effective recruitment...
July 2017: Bioethics
https://www.readbyqxmd.com/read/28592553/accurate-and-rapid-differentiation-of-acinetobacter-baumannii-strains-by-raman-spectroscopy-a-comparative-study
#19
Meron Ghebremedhin, Rae Heitkamp, Shubha Yesupriya, Bradford Clay, Nicole J Crane
In recent years, matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has become the standard for routine bacterial species identification due to its rapidity and low costs for consumables compared to those of traditional DNA-based methods. However, it has been observed that strains of some bacterial species, such as Acinetobacter baumannii strains, cannot be reliably identified using mass spectrometry (MS). Raman spectroscopy is a rapid technique, as fast as MALDI-TOF, and has been shown to accurately identify bacterial strains and species...
August 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28548835/rapid-deposition-of-uniform-polydopamine-coatings-on-nanoparticle-surfaces-with-controllable-thickness
#20
Nazar Orishchin, Cameron C Crane, Matthew Brownell, Tengjiao Wang, Samuel Jenkins, Min Zou, Arun Nair, Jingyi Chen
Polydopamine is a bioinspired, versatile material that can adhere to bulk and nanoscale surfaces made of disparate materials to improve their physical and chemical properties in many applications. The typical methods to coat polydopamine on the nanoparticle substrates usually take several hours to a day. This work successfully applies a dispersion method to form a controllable, uniform coating on a nanoparticle surface within minutes. Using plasmonic Ag nanoparticles as a substrate, the coating thickness can be monitored using a spectroscopic method based on the extinction peak shifts of the Ag nanoparticles...
June 6, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
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