keyword
https://read.qxmd.com/read/38534233/detection-of-cannabinoids-in-oral-fluid-specimens-as-the-preferred-biological-matrix-for-a-point-of-care-biosensor-diagnostic-device
#21
REVIEW
Călin Trif, Dorin Harpaz, Evgeni Eltzov, Yardnapar Parcharoen, Chiravoot Pechyen, Robert S Marks
An increasing number of countries have started to decriminalize or legalize the consumption of cannabis for recreational and medical purposes. The active ingredients in cannabis, termed cannabinoids, affect multiple functions in the human body, including coordination, motor skills, memory, response time to external stimuli, and even judgment. Cannabinoids are a unique class of terpeno-phenolic compounds, with 120 molecules discovered so far. There are certain situations when people under the influence of cannabis may be a risk to themselves or the public safety...
February 27, 2024: Biosensors
https://read.qxmd.com/read/38533764/the-efficacy-and-safety-of-neubotulinumtoxina-for-the-treatment-of-forehead-horizontal-lines-in-asians-a-clinical-prospective-interventional-split-face-study
#22
JOURNAL ARTICLE
Jessica Jane Sy, Raymond Wu, Jovian Wan, Soo-Bin Kim, Kyu-Ho Yi
BACKGROUND: Botulinum toxin injections are widely sought after in the field of medical aesthetics, offering consumers a variety of brand choices. Two commonly available botulinum toxin products, onabotulinumtoxinA and neubotulinumtoxinA, are featured in numerous clinics, leading many to question whether there are discernible differences in results, given their varying price ranges. OBJECTIVE: To evaluate the efficacy and safety of neubotulinumtoxinA for the treatment of forehead horizontal lines...
April 2024: Skin Research and Technology
https://read.qxmd.com/read/38533749/should-i-stay-or-should-i-go-a-rapid-qualitative-study-of-principal-deteriorating-factors-experienced-by-nurses-relating-to-their-intentions-to-leave-their-current-position-in-a-medical-hospital-department
#23
JOURNAL ARTICLE
Connie Berthelsen, Carrinna Aviaja Hansen
BACKGROUND: High nurse turnover in hospitals is a worldwide problem with dire consequences for patient care such as increased mortality and a decrease in patient safety. A specific effort to retain nurses is urgently needed due to the many vacant nursing positions, especially across the Medical hospital departments. AIM: To identify the principal deteriorating factors experienced by nurses relating to their intentions to leave the medical department at a university hospital...
March 27, 2024: Scandinavian Journal of Caring Sciences
https://read.qxmd.com/read/38533739/rozanolixizumab-a-new-therapy-in-the-treatment-of-myasthenia-gravis
#24
REVIEW
Emily M Hitt
OBJECTIVE: The aims of this article are to review the clinical aspects of rozanolixizumab, to describe clinical trial results that led to the drug's approval, and to examine the impact on patient care to aid clinical decision making. DATA SOURCES: A PubMed search was conducted using the terms Rystiggo ™, rozanolixizumab , rozanolixizumab therapy , and myasthenia gravis . The most recent prescribing information was also used for information relating to the drug and for identification of pertinent studies...
March 27, 2024: Annals of Pharmacotherapy
https://read.qxmd.com/read/38533699/business-continuity-plan-in-the-management-and-operations-of-hospitals-first-experience-to-certify-the-pdta-processes-with-the-requirements-defined-by-iso-22301-2019-in-emergency-medical-services
#25
JOURNAL ARTICLE
Lucio Dell'Atti, Roberto Papa, Leonardo Incicchitti, Maria Katia Zanni, Andrea Zampa, Michele Caporossi
BACKGROUND: A business continuity plan (BCP) facilitates the performance of primary functions during emergencies or other situations that can disrupt normal operations. If risk management is done analytically, a business impact analysis (BIA), according to ISO 22301 certification, makes it possible to define the best strategy for supporting the company's assets and image, optimizing the operational efficiency of service recovery and redesigning spaces for health. Since 2015, our healthcare company has embarked on a certification process for all sectors and activities through the implementation and development of diagnostic and therapeutic paths for operational diagnos-tic-therapeutic-assistance pathways (PDTAs)...
2024: Journal of Emergency Management: JEM
https://read.qxmd.com/read/38533388/anaesthetic-records-an-evaluation-of-variation-across-england
#26
R Fenton, C Thompson, S Drake, L Foley, T M Cook
We collected blank non-specialist anaesthetic records from 71 National Health Service Trusts in England. A data set was established by collating all data items found in an initial tranche of 28 records. All 71 records were subsequently analysed for each data item in this data set. We found significant variation: the most populated record included 216 data items and the least included 38 data items: a greater than five-fold variation. There was significant variation in the inclusion of data items commonly considered important to patient safety; 42% of records omitted documentation of fasting status, 72% omitted documentation of a discussion around the risk of accidental awareness during general anaesthesia, 92% omitted documentation of quantitative neuromuscular blockade monitoring and 63% omitted documentation for 'Stop Before You Block' when performing regional anaesthesia...
2024: Anaesthesia reports
https://read.qxmd.com/read/38533308/safety-and-long-term-outcomes-of-remote-cardiac-rehabilitation-in-coronary-heart-disease-patients-a-systematic-review
#27
REVIEW
Varsamo Antoniou, Eleni Kapreli, Constantinos H Davos, Ladislav Batalik, Garyfallia Pepera
OBJECTIVE: To systematically review the safety and the long-term mortality and morbidity risk-rates of the remotely-delivered cardiac rehabilitation (RDCR) interventions in coronary heart disease (CHD) patients. METHODS: The protocol was registered in the International Prospective Register of Systematic Reviews (CRD42023455471). Five databases (Pubmed, Scopus, Cochrane Central Register of Controlled Trials in the Cochrane Library, Cinahl and Web of Science) were reviewed from January 2012 up to August 2023...
2024: Digital Health
https://read.qxmd.com/read/38533254/a-real-world-disproportionality-analysis-of-everolimus-data-mining-of-the-public-version-of-fda-adverse-event-reporting-system
#28
JOURNAL ARTICLE
Bin Zhao, Yumei Fu, Shichao Cui, Xiangning Chen, Shu Liu, Lan Luo
Background: Everolimus is an inhibitor of the mammalian target of rapamycin and is used to treat various tumors. The presented study aimed to evaluate the Everolimus-associated adverse events (AEs) through data mining of the US Food and Drug Administration Adverse Event Reporting System (FAERS). Methods: The AE records were selected by searching the FDA Adverse Event Reporting System database from the first quarter of 2009 to the first quarter of 2022. Potential adverse event signals were mined using the disproportionality analysis, including reporting odds ratio the proportional reporting ratio the Bayesian confidence propagation neural network and the empirical Bayes geometric mean and MedDRA was used to systematically classify the results...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38533165/bee-sting-venom-as-a-viable-therapy-for-breast-cancer-a-review-article
#29
REVIEW
Aabhas Bindlish, Anupama Sawal
Breast cancer is a kind of aggressive cancer that significantly affects women worldwide, thus making research on alternative and new therapies necessary. The potential impact of bee venom on breast cancer is the main subject of this analysis of this research article. Bee venom has drawn the attention of the world with the help of its constituent ingredients, namely the bioactive compounds, enzymes, and complex blend of proteins. They have a particularly varied chemical makeup and proven anti-cancer capabilities...
February 2024: Curēus
https://read.qxmd.com/read/38532901/a-6-year-old-with-childhood-absence-epilepsy-and-motor-hyperactivity
#30
JOURNAL ARTICLE
Stéphane Auvin
A case study of a child with childhood absence epilepsy and hyperactivity introduces the discussion around the psychiatric diagnosis, differential considerations, and pharmacologic treatment options for ADHD/hyperactivity in children with epilepsy. Most of the time, ADHD in children with epilepsy is an inattentive form. The assessment emphasizes the need to differentiate ADHD symptoms from other psychiatric comorbidities. This is also crucial to evaluate when symptoms emerged, their impact on daily life, and if it could be a potential medication side effect...
2024: Epilepsy & behavior reports
https://read.qxmd.com/read/38532861/benefits-of-a-clinical-pathway-in-total-knee-arthroplasty
#31
JOURNAL ARTICLE
Márcio de Castro Ferreira, Gilvânia Silva, Carolina Padrão Amorim Marinelli, Julia Souza de Oliveira, Pedro Aurélio Mathiasi, Gilberto Luis Camanho
OBJECTIVE: Demonstrate whether a multiprofessional Clinical Pathway Program in Total Knee Arthroplasty (CPPA) contributesto optimizing hospital care. METHOD: Retrospective study of medical data of care indicators in 310 patients divided into two groups: A- who underwent arthroplasty in the last biennium before the introduction of the CPPA (n=144) and group B- who underwent TKA in the biennium after the introduction of the CPPA (n=166). RESULTS: Postoperative showed a significant difference in favor of group B over group A for hospitalization time in days 4...
2024: Acta Ortopedica Brasileira
https://read.qxmd.com/read/38532688/board-certified-psychiatric-pharmacists-and-their-potential-role-in-addressing-behavioral-health-workforce-shortages
#32
JOURNAL ARTICLE
Carla D Cobb, Talia Puzantian, Michael Shuman
Board-certified psychiatric pharmacists (BCPPs) are doctorate-level, board-certified experts in managing medications for people living with psychiatric disorders, including substance use disorders. BCPPs work as part of an integrated health care team that provides comprehensive medication management focused on optimizing medication-related outcomes and ensuring the safety of the prescribed medications. The authors describe BCPP education and training, settings in which BCPPs practice, and in what roles. Current policies that limit BCPP involvement in behavioral health care and proposed solutions to support the role of BCPPs in addressing behavioral health workforce shortages are discussed...
March 27, 2024: Psychiatric Services: a Journal of the American Psychiatric Association
https://read.qxmd.com/read/38532677/-improving-the-standby-process-completion-rate-among-nurses-for-high-risk-neonates
#33
JOURNAL ARTICLE
Mo-Fen Wu, Li-Ying Chung
BACKGROUND & PROBLEMS: Readiness process effectiveness significantly impacts the safety of high-risk neonates and requires an immediately responsive and well-trained healthcare team. Analysis of our unit found the high-risk neonatal standby process completion rate among nursing staff to be very low. Reasons for this poor level of performance included absence of standardized procedures for high-risk neonatal standby, lack of an auditing system, inadequate education and training, multiple medical supplies in the standby kits, absence of a checklist for the kits, and failure to regularly inventory the contents of these kits...
April 2023: Hu Li za Zhi the Journal of Nursing
https://read.qxmd.com/read/38532641/developing-a-process-to-measure-actual-harm-from-medication-errors-in-paediatric-inpatients-from-design-to-implementation
#34
JOURNAL ARTICLE
Virginia Mumford, Magdalena Z Raban, Ling Li, Erin Fitzpatrick, Amanda Woods, Alison Merchant, Tim Badgery-Parker, Peter Gates, Melissa Baysari, Ric O Day, Geoffrey Ambler, Luciano Dalla-Pozza, Madlen Gazarian, Alan Gardo, Peter Barclay, Les White, Johanna I Westbrook
AIMS: The potential harm associated with medication errors is widely reported, but data on actual harm are limited. When actual harm has been measured, assessment processes are often poorly described, limiting their ability to be reproduced by other studies. Our aim was to design and implement a new process to assess actual harm resulting from medication errors in paediatric inpatient care. METHODS: Prescribing errors were identified through retrospective medical record reviews (n = 26 369 orders) and medication administration errors through direct observation (n = 5137 administrations) in a tertiary paediatric hospital...
March 26, 2024: British Journal of Clinical Pharmacology
https://read.qxmd.com/read/38532534/unilateral-magnetic-resonance-imaging-guided-laser-interstitial-thermal-therapy-thalamotomy-for-essential-tremor
#35
JOURNAL ARTICLE
Mickael Aubignat, Mélissa Tir, Martial Ouendo, Salem Boussida, Jean-Marc Constans, Michel Lefranc
BACKGROUND: Essential tremor (ET) affects numerous adults, impacting quality of life (QOL) and often defying pharmacological treatment. Surgical interventions like deep brain stimulation (DBS) and lesional approaches, including radiofrequency, gamma-knife radiosurgery, and magnetic resonance imaging (MRI)-guided focused ultrasound, offer solutions but are not devoid of limitations. OBJECTIVES: This retrospective, single-center, single-blinded pilot study aimed to assess the safety and efficacy of unilateral MRI-guided laser interstitial thermal therapy (MRIg-LITT) thalamotomy for medically intractable ET...
March 26, 2024: Movement Disorders: Official Journal of the Movement Disorder Society
https://read.qxmd.com/read/38532487/medicinal-plants-and-natural-products-for-treating-overactive-bladder
#36
REVIEW
Huanxian Chen, Maggie Pui Man Hoi, Simon Ming Yuen Lee
BACKGROUND: Overactive bladder (OAB) presents a high prevalence of 16-18% worldwide. The pathophysiology of OAB is still poorly understood while effective therapy or countermeasure are very limited. On the other hand, medicinal plants and herbal remedies have been utilized for treating lower urinary tract symptoms (LUTS) in both Eastern and Western cultures since ancient times. In recent years, accumulating progress has also been made in OAB treatment research by using medicinal plants...
March 27, 2024: Chinese Medicine
https://read.qxmd.com/read/38532468/comparing-the-clinical-practice-and-prescribing-safety-of-locum-and-permanent-doctors-observational-study-of-primary-care-consultations-in-england
#37
JOURNAL ARTICLE
Christos Grigoroglou, Kieran Walshe, Evangelos Kontopantelis, Jane Ferguson, Gemma Stringer, Darren M Ashcroft, Thomas Allen
BACKGROUND: Temporary doctors, known as locums, are a key component of the medical workforce in the NHS but evidence on differences in quality and safety between locum and permanent doctors is limited. We aimed to examine differences in the clinical practice, and prescribing safety for locum and permanent doctors working in primary care in England. METHODS: We accessed electronic health care records (EHRs) for 3.5 million patients from the CPRD GOLD database with linkage to Hospital Episode Statistics from 1st April 2010 to 31st March 2022...
March 27, 2024: BMC Medicine
https://read.qxmd.com/read/38532396/retinal-injury-from-a-laser-skin-resurfacing-device-during-medical-tourism-a-public-health-concern
#38
JOURNAL ARTICLE
Lester H Lambert, Brett L Tompkins, Ian C Uber, Kapil G Kapoor, David J Ramsey
BACKGROUND: Laser skin resurfacing is a popular cosmetic procedure for noninvasive skin rejuvenation. Since health insurance plans often do not cover these types of procedures, patients often pay out of pocket. Consequently, there is an incentive to go abroad, where prices are more affordable. However, practitioners in destination countries may lack rigorous training on laser safety, regulatory oversight, or licensing, especially on devices used for "cosmetic" procedures. In certain cases, this can lead to tragic outcomes, especially when underqualified practitioners operate medical-grade laser devices...
March 26, 2024: BMC Ophthalmology
https://read.qxmd.com/read/38532273/men-s-experiences-of-a-personalised-appearance-based-facial-morphing-safer-drinking-intervention
#39
JOURNAL ARTICLE
Ian R Burgess, Alison Owen, Keira Scholtens, Sarah Grogan
Risky alcohol consumption behaviours remain commonplace, representing a major threat to health and safety, and are especially evidenced by young university students. Consequently, new interventions targeting this high-risk group are required. The current study investigated young male university students' experiences of a personalised, appearance-based, facial morphing, safer drinking intervention. Twenty-five male student participants were recruited, aged 18-34 years. Inductive thematic analysis of data gathered whilst participants were immersed in the intervention, and thereby exposed to alcohol-aged images of their own faces, produced four primary themes: alcohol as a threat to appearance and health, motivations to protect appearance, motivational aspects of the intervention, and proposed improvements and applications...
March 26, 2024: Journal of Health Psychology
https://read.qxmd.com/read/38532234/stigma-risks-and-benefits-of-medicinal-cannabis-use-among-australians-with-cancer
#40
JOURNAL ARTICLE
Julia N Morris, Jessica Loyer, Jason Blunt
PURPOSE: People with cancer who use medicinal cannabis do so despite risks associated with limited clinical evidence, legalities, and stigma. This study investigated how Australians with cancer rationalise their medicinal cannabis use despite its risks. METHODS: Ten adults (5 males and 5 females; mean age of 53.3) who used cannabis medicinally for their cancer were interviewed in 2021-2022 about how they used and accessed the substance, attitudes and beliefs underpinning their use, and conversations with others about medicinal cannabis...
March 27, 2024: Supportive Care in Cancer
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