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https://www.readbyqxmd.com/read/29036941/breast-implant-associated-anaplastic-large-cell-lymphoma-in-a-transgender-woman
#1
Mintsje de Boer, Wouter B van der Sluis, Jan P de Boer, Lucy I H Overbeek, Flora E van Leeuwen, Hinne A Rakhorst, René R W J van der Hulst, Nathalie J Hijmering, Mark-Bram Bouman, Daphne de Jong
Breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL) is a rare but serious complication in patients with breast implants, Patients are at risk of BIA-ALCL whether they receive breast implants for cosmetic reasons or for reconstructive purposes after surgery for breast cancer or prophylactic mastectomy. During the past decade, an increased number of reports have addressed BIA-ALCL. Herein, we describe BIA-ALCL in a transgender woman. The patient received breast implants as part of her gender transition and was diagnosed with BIA-ALCL 20 years later...
September 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29036544/corrigendum-and-response-to-the-letter-from-warren-et-al
#2
Hiroki Takanari, Magda S C Fontes, Marcel A G van der Heyden, Marc A Vos, Toon A B van Veen
No abstract text is available yet for this article.
September 29, 2017: Cardiovascular Research
https://www.readbyqxmd.com/read/29036237/-priorities-and-recommendations-in-oral-health-care-for-older-people
#3
K Jerkovic, B Everaars, G J van der Putten
The oral health of older people in the Netherlands, especially those who are vulnerable and dependent on care, is insufficient. Older people and other stakeholders participated in a so-called Priority Setting Partnership study to identify hindrances that have been experienced in oral health care and to distil from their experience items for the agenda for further research. For this reason, discussions were held in 5 focus groups with respectively 1 group of older people, caregivers, external parties and health care professionals...
October 2017: Nederlands Tijdschrift Voor Tandheelkunde
https://www.readbyqxmd.com/read/29036225/human-plasma-derived-c1-esterase-inhibitor-concentrate-has-limited-effect-on-house-dust-mite-induced-allergic-lung-inflammation-in-mice
#4
Ingrid Stroo, Jack Yang, Adam A Anas, J Daan de Boer, Gerard van Mierlo, Dorina Roem, Diana Wouters, Ruchira Engel, Joris J T H Roelofs, Cornelis van 't Veer, Tom van der Poll, Sacha Zeerleder
C1 esterase inhibitor (C1-INH) can inhibit multiple pathways (complement, contact-kinin, coagulation, and fibrinolysis) that are all implicated in the pathophysiology of asthma. We explored the effect of human plasma-derived C1-INH on allergic lung inflammation in a house dust mite (HDM) induced asthma mouse model by daily administration of C1-INH (15 U) during the challenge phase. NaCl and HDM exposed mice had comparable plasma C1-INH levels, while bronchoalveolar lavage fluid (BALF) levels were increased in HDM exposed mice coinciding with slightly reduced activation of complement (C5a)...
2017: PloS One
https://www.readbyqxmd.com/read/29035982/comparison-of-the-effect-of-5-different-treatment-options-for-managing-patellar-tendinopathy-a-secondary-analysis
#5
Dafne van Rijn, Inge van den Akker-Scheek, Mirjam Steunebrink, Ron L Diercks, Johannes Zwerver, Henk van der Worp
OBJECTIVE: Currently, no treatments exist for patellar tendinopathy (PT) that guarantee quick and full recovery. Our objective was to assess which treatment option provides the best chance of clinical improvement and to assess the influence of patient and injury characteristics on the clinical effect of these treatments. DESIGN: A secondary analysis was performed on the combined databases of 3 previously performed double-blind randomized controlled trials. PATIENTS: In total, 138 patients with PT were included in the analysis...
October 10, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29035839/insights-into-protein-misfolding-and-aggregation-enabled-by-solid-state-nmr-spectroscopy
#6
REVIEW
Patrick C A van der Wel
The aggregation of proteins and peptides into a variety of insoluble, and often non-native, aggregated states plays a central role in many devastating diseases. Analogous processes undermine the efficacy of polypeptide-based biological pharmaceuticals, but are also being leveraged in the design of biologically inspired self-assembling materials. This Trends article surveys the essential contributions made by recent solid-state NMR (ssNMR) studies to our understanding of the structural features of polypeptide aggregates, and how such findings are informing our thinking about the molecular mechanisms of misfolding and aggregation...
October 4, 2017: Solid State Nuclear Magnetic Resonance
https://www.readbyqxmd.com/read/29035615/improving-mobility-performance-in-wheelchair-basketball
#7
Thom T J Veeger, Annemarie M H De Witte, Monique A M Berger, Rienk M A Van Der Slikke, Dirkjan H E J Veeger, Marco J M Hoozemans
OBJECTIVE: This study aimed to investigate which characteristics of athlete, wheelchair and athlete-wheelchair interface are the best predictors of wheelchair basketball mobility performance. DESIGN: Sixty experienced wheelchair basketball players performed a wheelchair mobility performance test to assess their mobility performance. To determine which variables were the best predictors of mobility performance, forward stepwise linear regression analyses were performed on a set of 33 characteristics, including ten athlete, nineteen wheelchair and four athlete-wheelchair interface characteristics...
October 16, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/29035406/novel-activity-based-probes-for-n-acylethanolamine-acid-amidase
#8
Rita Petracca, Elisa Romeo, Marc P Baggelaar, Marta Artola, Silvia Pontis, Stefano Ponzano, Herman S Overkleeft, Mario van der Stelt, Daniele Piomelli
The cysteine hydrolase, N-acylethanolamine acid amidase (NAAA) is a promising target for analgesic and anti-inflammatory drugs. Here, we describe the development of two unprecedented NAAA-reactive activity-based probes as research tools for application in the discovery of new inhibitors and for the in-depth characterization of NAAA in its cellular environment.
October 16, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/29035360/ezh2-promotes-degradation-of-stalled-replication-forks-by-recruiting-mus81-through-histone-h3-trimethylation
#9
Beatrice Rondinelli, Ewa Gogola, Hatice Yücel, Alexandra A Duarte, Marieke van de Ven, Roxanne van der Sluijs, Panagiotis A Konstantinopoulos, Jos Jonkers, Raphaël Ceccaldi, Sven Rottenberg, Alan D D'Andrea
The emergence of resistance to poly-ADP-ribose polymerase inhibitors (PARPi) poses a threat to the treatment of BRCA1 and BRCA2 (BRCA1/2)-deficient tumours. Stabilization of stalled DNA replication forks is a recently identified PARPi-resistance mechanism that promotes genomic stability in BRCA1/2-deficient cancers. Dissecting the molecular pathways controlling genomic stability at stalled forks is critical. Here we show that EZH2 localizes at stalled forks where it methylates Lys27 on histone 3 (H3K27me3), mediating recruitment of the MUS81 nuclease...
October 16, 2017: Nature Cell Biology
https://www.readbyqxmd.com/read/29035135/draft-de-novo-genome-sequence-of-agapornis-roseicollis-for-application-in-avian-breeding
#10
Henriëtte van der Zwan, Francois van der Westhuizen, Carina Visser, Rencia van der Sluis
In aviculture, lovebirds are considered one of the most popular birds to keep. This African parakeet is known for its range of plumage colors and ease to tame. Plumage variation is the most important price-determining trait of these birds, and also the main selection criterion for breeders. Currently, no genetic screening tests for traits of economic importance or to confirm pedigree data are available for any of the nine lovebird species. As a starting point to develop these tests, the de novo genome of Agapornis roseicollis (rosy-faced lovebird) was sequenced, assembled, and annotated...
October 16, 2017: Animal Biotechnology
https://www.readbyqxmd.com/read/29035091/inverse-relationship-between-soluble-rage-and-risk-for-bronchopulmonary-dysplasia
#11
John T Benjamin, Riet van der Meer, James C Slaughter, Steven Steele, Erin J Plosa, Jennifer M Sucre, Paul E Moore, Judy L Aschner, Timothy S Blackwell, Lisa R Young
No abstract text is available yet for this article.
October 16, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29035067/executive-functioning-in-relation-to-coping-in-mild-versus-moderate-severe-traumatic-brain-injury
#12
Sandra E Rakers, Myrthe E Scheenen, Herma J Westerhof-Evers, Myrthe E de Koning, Harm J van der Horn, Joukje van der Naalt, Jacoba M Spikman
OBJECTIVE: To examine associations between executive functioning (EF) and coping styles, separately for mild and moderate-severe traumatic brain injury (TBI) in the chronic phase postinjury. METHOD: Patients with mild (n = 47) and moderate-severe TBI (n = 59) were included, in addition to healthy controls (HCs; n = 51). Assessment consisted of EF tests (Trail Making Test, Zoo Map Test, Controlled Oral Word Association Test) and questionnaires examining EF (Dysexecutive Questionnaire) and coping styles (Utrecht Coping List)...
October 16, 2017: Neuropsychology
https://www.readbyqxmd.com/read/29035014/nationwide-trends-in-chemotherapy-use-and-survival-of-elderly-patients-with-metastatic-pancreatic-cancer
#13
Lydia G M van der Geest, Nadia Haj Mohammad, Marc G H Besselink, Valery E P P Lemmens, Johanneke E A Portielje, Hanneke W M van Laarhoven, J Hanneke W Wilmink
Despite an aging population and underrepresentation of elderly patients in clinical trials, studies on elderly patients with metastatic pancreatic cancer are scarce. This study investigated the use of chemotherapy and survival in elderly patients with metastatic pancreatic cancer. From the Netherlands Cancer Registry, all 9407 patients diagnosed with primary metastatic pancreatic adenocarcinoma in 2005-2013 were selected to investigate chemotherapy use and overall survival (OS), using Kaplan-Meier and Cox proportional hazard regression analyses...
October 16, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/29034984/sensory-quality-and-fatty-acid-content-of-springbok-antidorcas-marsupialis-meat-influence-of-farm-location-and-gender
#14
Jeannine Neethling, Magdalena Muller, Marieta van der Rijst, Louwrens C Hoffman
BACKGROUND: Springbok are harvested for meat production irrespective of farm location or gender from which the meat is derived. This study investigated the influence of farm location (three farms containing different vegetation types) and gender on the sensory quality of springbok longissimus thoracis et lumborum muscle. The sensory profile (aroma, flavour and texture) was determined by descriptive sensory analysis, in addition to determining the physical meat quality, proximate and fatty acid composition...
October 16, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29034911/collision-cross-sections-and-ion-structures-development-of-a-general-calculation-method-via-high-quality-ion-mobility-measurements-and-theoretical-modeling
#15
Jong Wha Lee, Kimberly L Davidson, Matthew F Bush, Hugh I Kim
Ion mobility mass spectrometry (IM-MS) has become an important tool for the structural investigation of ions in the gas phase. Accurate theoretical evaluation of ion collision cross sections (CCSs) is essential for the effective application of IM-MS in structural studies. However, current theoretical tools have limitations in accurately describing a broad range of ions from small molecules to macromolecules. Significant difficulties in developing theoretical tools for CCS calculations are associated with obtaining high-quality experimental data and molecular models...
October 16, 2017: Analyst
https://www.readbyqxmd.com/read/29034600/no-adverse-programming-by-post-weaning-dietary-fructose-of-body-weight-adiposity-glucose-tolerance-or-metabolic-flexibility
#16
Lianne M S Bouwman, José M S Fernández-Calleja, Hans J M Swarts, Inge van der Stelt, Annemarie Oosting, Jaap Keijer, Evert M van Schothorst
SCOPE: Metabolic programming can occur not only in the perinatal period, but also post-weaning. This study aimed to assess whether fructose, in comparison to glucose, in the post-weaning diet programs body weight, adiposity, glucose tolerance, metabolic flexibility and health at adult age. METHODS AND RESULTS: Three-week-old male and female C57BL6/JRccHsd mice were given an intervention diet with 32 en% glucose or fructose for only three weeks. Next, all animals were switched to the same 40 en% high fat diet for nine weeks...
October 16, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/29034545/a-pilot-intervention-to-reduce-postpartum-weight-retention-and-central-adiposity-in-first-time-mothers-results-from-the-mums-online-online-lifestyle-nutrition-exercise-study
#17
P van der Pligt, K Ball, K D Hesketh, M Teychenne, D Crawford, P J Morgan, C E Collins, K J Campbell
BACKGROUND: Postpartum weight retention (PPWR) increases the risk for obesity and complications during subsequent pregnancies. Few interventions have been successful in limiting PPWR in mothers. The present study assessed the effectiveness of the mums OnLiNE (Online, Lifestyle, Nutrition & Exercise) intervention with respect to reducing PPWR and improving diet, physical activity and sedentary behaviour. METHODS: A subsample of first-time mothers enrolled in the Extended Melbourne Infant Feeding Activity and Nutrition Trial (InFANT Extend) completed the nonrandomised mums OnLiNE intervention...
October 16, 2017: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/29033931/plasmodium-berghei-nk65-in-combination-with-ifn-%C3%AE-induces-endothelial-glucocorticoid-resistance-via-sustained-activation-of-p38-and-jnk
#18
Karolina A Zielińska, Lode de Cauwer, Sofie Knoops, Kristof Van der Molen, Alexander Sneyers, Jonathan Thommis, J Brian De Souza, Ghislain Opdenakker, Karolien De Bosscher, Philippe E Van den Steen
Malaria-associated acute respiratory distress syndrome (MA-ARDS) is an often lethal complication of malaria. Currently, no adequate therapy for this syndrome exists. Although glucocorticoids (GCs) have been used to improve clinical outcome of ARDS, their therapeutic benefits remain unclear. We previously developed a mouse model of MA-ARDS, in which dexamethasone treatment revealed GC resistance. In the present study, we investigated GC sensitivity of mouse microvascular lung endothelial cells stimulated with interferon-γ (IFN-γ) and Plasmodium berghei NK65 (PbNK65)...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29033915/evaluation-of-the-swabbing-of-disposable-absorbent-incontinence-products-for-assessing-the-carriage-of-multiresistant-enterobacteriaceae-in-nursing-home-residents
#19
Alexis Naf, Marie Decalonne, Sandra Dos Santos, Laurent Mereghetti, Nathalie L van der Mee-Marquet
We compared the performance of incontinence product (IP) and rectal swabbing for the detection of multidrug-resistant Enterobacteriaceae (MDRE) carriage in a large multicenter study conducted in February 2017 among the residents of 23 French nursing homes. The study included 547 residents who habitually wore IP, 88 of whom were MDRE carriers (16.1%). Positive results were obtained for both rectal and IP swabs for 64 of these residents, for rectal swabs only for 22 and for IP swabs only for two of these patients...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29033875/-i-will-survive-a-construct-validation-study-on-the-measurement-of-sustainable-employability-using-different-age-conceptualizations
#20
Pascale M Le Blanc, Beatrice I J M Van der Heijden, Tinka Van Vuuren
Though the importance of sustainable employability throughout people's working life is undisputed, up till now only one attempt for a conceptual definition has been made (van der Klink et al., 2016). Following the suggestions to further refine and improve this definition recently put forward by Fleuren et al. (2016), we propose an approach to sustainable employability that is based on the Ability-Motivation-Opportunity (AMO) framework, and incorporates three indicators: the ability, the motivation, and the opportunity to continue working, respectively...
2017: Frontiers in Psychology
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